Explain in brief about leukotrienes and prostaglandins Leukotrienes and prostaglandins are formed only when the mast cell undergo degranulation and enzymatic break down of phospholipids in the plasma membrane ?

Question

Explain in brief about leukotrienes and prostaglandins Leukotrienes and prostaglandins are formed only when the mast cell undergo degranulation and enzymatic break down of phospholipids in the plasma membrane ?

asked Jan 6, 2022 by anonymous

1 Answer

Answer :

The effects produced by them are more pronounced and long lasting than histamine. Leukotrienes mediate mucous production and bronchoconstriction. Prostaglandin D2 causes bronchoconstriction.

answered Jan 6, 2022 by anonymous
selected Jan 6, 2022

Related questions

Explain in brief about histamine It is formed by the decarboxylation of amino acid histidine ?

Description : Explain in brief about histamine It is formed by the decarboxylation of amino acid histidine ?

Last Answer : It accounts for 10% of granule weight. This histamine binds to specific receptors on various target cells.

Allergy is immediate hypersensitivity mediated by _____and mast cell degranulation a) IgG b) IgE c) IgM d) IgA e) IgD

Description : Allergy is immediate hypersensitivity mediated by _____and mast cell degranulation a) IgG b) IgE c) IgM d) IgA e) IgD

Last Answer : Ans: B

Eicosanoids mediate inflammation in a variety of ways. Of the following statements, which are true with regard to this? a. Eicosanoids are stored in cytoplasmic granules for release after receptor mediated signaling b. Eicosanoids include prostaglandins, thromboxanes, leukotrienes and lipoxins c. Eicosanoids generally have a plasma half-life measured in hours d. Physiologic responses to eicosanoids include vasodilatation, vasoconstriction, increased vascular permeability and both chemotaxis and chemoattractant inhibition

Description : Eicosanoids mediate inflammation in a variety of ways. Of the following statements, which are true with regard to this? a. Eicosanoids are stored in cytoplasmic granules ... include vasodilatation, vasoconstriction, increased vascular permeability and both chemotaxis and chemoattractant inhibition

Last Answer : Answer: b, d The eicosanoids are derived from arachidonic acid (eicosatetraenoic acid) and consist of prostaglandins, thromboxanes, leukotrienes and lipoxins. The eicosanoids are not ... nervous system d. Mononuclear phagocytes release a variety of proinflammatory cytokines and growth factors

What is the reaction-taking place when H2 receptor binds to mast cells and basophils ?

Description : What is the reaction-taking place when H2 receptor binds to mast cells and basophils ?

Last Answer : When H2 binds to mast cells and basophils it suppresses degranulation.

Explain in brief about cytokines Cytokines activate inflammatory cells such as neutrophils and eosnophils ?

Description : Explain in brief about cytokines Cytokines activate inflammatory cells such as neutrophils and eosnophils ?

Last Answer : IL-5 is important in activation of eosnophils, IL-4 increases IgE production by B-cells. IL-4, Il-5, IL-6, TNF-a has been secreted by human mast cells.

How is the concentration of drugs in human plasma defined ?

Description : How is the concentration of drugs in human plasma defined ?

Last Answer : Some drugs bind extensively to plasma proteins (Warfarin binds 99%) whereas others have virtually no binding. Extraction depends on the type of drug - there are different standard techniques for acidic, ... but such controls are again specific for each drug and use specific marker compounds.

Which of the following statement(s) is/are true concerning cellular ion channels? a. Ion channels are transmembrane proteins that form pores that can conduct ions across the plasma membrane b. Ion channels are formed by membrane-spanning peptides that are arranged so that polar moieties line a central core c. Ion channel proteins undergo conformational changes between open states and closed states d. Ion channels can be blocked

Description : Which of the following statement(s) is/are true concerning cellular ion channels? a. Ion channels are transmembrane proteins that form pores that can conduct ions across the plasma membrane b. ... undergo conformational changes between open states and closed states d. Ion channels can be blocked

Last Answer : Answer: a, b, c, d Ion channels are transmembrane proteins that form pores that can conduct ions across the plasma membrane. Ion channels are formed by membrane-spanning peptides that are arranged ... be blocked by ions or organic compounds that enter the channel, bind there, and occlude the pore

Lipo-oxygenase is required for the synthesis of (A) Prostaglandins (B) Leukotrienes (C) Thromboxanes (D) All of these

Description : Lipo-oxygenase is required for the synthesis of (A) Prostaglandins (B) Leukotrienes (C) Thromboxanes (D) All of these

Last Answer : Answer : B

Slow reacting Substance of Anaphylaxis is a mixture of (A) Prostaglandins (B) Prostacyclins (C) Thromboxanes (D) Leukotrienes

Description : Slow reacting Substance of Anaphylaxis is a mixture of (A) Prostaglandins (B) Prostacyclins (C) Thromboxanes (D) Leukotrienes

Last Answer : Answer : D

Anti-inflammatory corticosteroids inhibit the synthesis of (A) Leukotrienes (B) Prostaglandins (C) Thromboxanes (D) All of these

Description : Anti-inflammatory corticosteroids inhibit the synthesis of (A) Leukotrienes (B) Prostaglandins (C) Thromboxanes (D) All of these

Last Answer : Answer : D

Cyclooxygenase-1 and –2 are responsible for (a) The synthesis of prostaglandins from arachidonate (b) The synthesis of leukotrienes from arachidonate (c) The conversion of ATP to cAMP (d) The metabolic degradation of cAMP (e) The conversion of GTP to cGMP

Description : Cyclooxygenase-1 and –2 are responsible for (a) The synthesis of prostaglandins from arachidonate (b) The synthesis of leukotrienes from arachidonate (c) The conversion of ATP to cAMP (d) The metabolic degradation of cAMP (e) The conversion of GTP to cGMP

Last Answer : Ans: A

Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) Cyclooxygenase 1 (b) Cyclooxygenase 2 (c) Glutathione – S – transferase (d) Lipoxygenase (e) Phospholipase A2

Description : Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) ... 2 (c) Glutathione - S - transferase (d) Lipoxygenase (e) Phospholipase A2

Last Answer : Ans: B

There are no preformed stores of the following autacoid/autacoids: A. Prostaglandins B. Leukotrienes C. Angiotensin II D. All of the above

Description : There are no preformed stores of the following autacoid/autacoids: A. Prostaglandins B. Leukotrienes C. Angiotensin II D. All of the above

Last Answer : D. All of the above

According to fluid mosaic model, plasma membrane is composed of (a) phospholipids and oligosaccharides (b) phospholipids and hemicellulose (c) phospholipids and integral proteins (d) phospholipids, extrinsic proteins and intrinsic proteins.

Description : According to fluid mosaic model, plasma membrane is composed of (a) phospholipids and oligosaccharides (b) phospholipids and hemicellulose (c) phospholipids and integral proteins (d) phospholipids, extrinsic proteins and intrinsic proteins.

Last Answer : (d) phospholipids, extrinsic proteins and intrinsic proteins.

In fluid mosaic model of plasma membrane (a) upper layer is non-polar and hydrophilic (b) upper layer is polar and hydrophobic (c) phospholipids form a bimolecular layer in middle part (d) proteins form a middle layer.

Description : In fluid mosaic model of plasma membrane (a) upper layer is non-polar and hydrophilic (b) upper layer is polar and hydrophobic (c) phospholipids form a bimolecular layer in middle part (d) proteins form a middle layer.

Last Answer : (c) phospholipids form a bimolecular layer in middle part

The plasma membrane consists mainly of (a) phospholipids embedded in a protein bilayer (b) proteins embedded in a phospholipid bilayer (c) proteins embedded in a polymer of glucose molecules (d) proteins embedded in a carbohydrate bilayer

Description : The plasma membrane consists mainly of (a) phospholipids embedded in a protein bilayer (b) proteins embedded in a phospholipid bilayer (c) proteins embedded in a polymer of glucose molecules (d) proteins embedded in a carbohydrate bilayer

Last Answer : (b) proteins embedded in a phospholipid bilayer

The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin

Description : The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin

Last Answer : Answer : D

How the phospholipids are arranged in the cell membrane?

Description : How the phospholipids are arranged in the cell membrane?

Last Answer : Two layers of phospholipids are arranged as a bilayer that formsthe basis of cell membrane structure. One layer has its hydrophilicheads neighbouring the surroundings whereas the other has ... the cytoplasm. The hydropholic fattyacid tails of both layers of phospholipid point towards thecentre.

Phospholipids are important cell membrane components since (A) They have glycerol (B) Form bilayers in water (C) Have polar and non-polar portions (D) Combine covalently with proteins

Description : Phospholipids are important cell membrane components since (A) They have glycerol (B) Form bilayers in water (C) Have polar and non-polar portions (D) Combine covalently with proteins

Last Answer : Answer : C

Phospholipids are important cell membrane components because (A) They have glycerol (B) They can form bilayers in water (C) They have both polar and non polar potions (D) They combine covalently with proteins

Description : Phospholipids are important cell membrane components because (A) They have glycerol (B) They can form bilayers in water (C) They have both polar and non polar potions (D) They combine covalently with proteins

Last Answer : Answer : C

The importance of phospholipids as constituent of cell membrane is because they possess (A) Fatty acids (B) Both polar and nonpolar groups (C) Glycerol (D) Phosphoric acid

Description : The importance of phospholipids as constituent of cell membrane is because they possess (A) Fatty acids (B) Both polar and nonpolar groups (C) Glycerol (D) Phosphoric acid

Last Answer : Answer : B

Which one of the following is not a constituent of cell membrane? (a) Glycolipids (b) Proline (c) Phospholipids (d) Cholesterol

Description : Which one of the following is not a constituent of cell membrane? (a) Glycolipids (b) Proline (c) Phospholipids (d) Cholesterol

Last Answer : (b) Proline

Between the layers of phospholipids in a cell membrane, there is an area that is: a) hydrophobic (pron: high-dro-fo-bick) b) hydrophillic (pron: high-dro-fill-ick) c) hygroscopic (pron: high-grow-scop-ick) d) hygrolipic (pron: high-grow-lip-ick)

Description : Between the layers of phospholipids in a cell membrane, there is an area that is: a) hydrophobic (pron: high-dro-fo-bick) b) hydrophillic (pron: high-dro-fill-ick) c) hygroscopic (pron: high-grow-scop-ick) d) hygrolipic (pron: high-grow-lip-ick)

Last Answer : ANSWER: A -- HYDROPHOBIC

What is an agretope ?

Description : What is an agretope ?

Last Answer : The region of an antigenic peptide, which binds to MCH molecule, is known as agretope.

What is agglutination ?

Description : What is agglutination ?

Last Answer : Clumping of particles or cells is called agglutination.

What is an agglutinin ?

Description : What is an agglutinin ?

Last Answer : A substance can mediate clumping of the cells or particles.

What is adoptive transfer ?

Description : What is adoptive transfer ?

Last Answer : The ability to participate in the immune response by the process of transplantation of cells is adoptive transfer.

What is an abzyme ?

Description : What is an abzyme ?

Last Answer : It is a monoclonal antibody, which has catalytic activity.

How viral load can be measured ?

Description : How viral load can be measured ?

Last Answer : Viral load is measured by PCR based techniques.

What is the first overt indication of AIDS ?

Description : What is the first overt indication of AIDS ?

Last Answer : The first overt indication of AIDS may be infection with the fungus Candida albicans, which causes sores in the mouth and in women vulvovaginal yeast infection is formed that will not respond to the treatment given.

What does HAART do ?

Description : What does HAART do ?

Last Answer : HAART will lower the viral load and improves the health of the patients who are suffering with AIDS.

What is the current treatment given to AIDS ?

Description : What is the current treatment given to AIDS ?

Last Answer : Current treatment given to AIDS is HAART (highly active anti retroviral therapy).It is a combination therapy.

What are major successful vaccines ?

Description : What are major successful vaccines ?

Last Answer : Major successful vaccines are live attenuated and heat killed vaccines.

What do most vaccines function as ?

Description : What do most vaccines function as ?

Last Answer : Most of the vaccines prevent disease but not infection.

What does myeloid immunodeficiency cause ?

Description : What does myeloid immunodeficiency cause ?

Last Answer : Myeloid immunodeficiency causes phagocytic function, which is impaired. Those who are affected with this will suffer with increase in susceptibility to bacterial infection.

What does immunodeficiency results ?

Description : What does immunodeficiency results ?

Last Answer : Immunodeficiency results in failure of one or more components of immune system.

What does HIV results ?

Description : What does HIV results ?

Last Answer : HIV results in impairment of immune function by depletion oh CD4+ T cells.

What is the treatment for HIV ?

Description : What is the treatment for HIV ?

Last Answer : Anti-retroviral drugs are given. They lower the viral load and gives relief from infection, but it is not permanent it is temporary relief i.e. it cannot cure.

How HIV infection is mainly spread ?

Description : How HIV infection is mainly spread ?

Last Answer : It is mainly spread by sexual contact, blood transfers and from HIV infected mother to child.

What is a provirus ?

Description : What is a provirus ?

Last Answer : It is the DNA representing, the genome of virus that has been integrated into the DNA of the host.

What is a retrovirus ?

Description : What is a retrovirus ?

Last Answer : It is a class of viruses having RNA genome and reverse transcriptase enzyme within virus cuspid.

How AIDS is caused ?

Description : How AIDS is caused ?

Last Answer : It is caused by the infection of HIV 1 i.e. human immunodeficiency virus.

What is the full form of AIDS ?

Description : What is the full form of AIDS ?

Last Answer : Full form of AIDS is acquired Immunodeficiency syndrome.

Why purified macromolecules are used as vaccines ?

Description : Why purified macromolecules are used as vaccines ?

Last Answer : To avoid the risk associated with attenuated and killed whole organism vaccines. 80.Name some purified macromolecules derived from pathogens. They are capsular polysaccharides, inactivated exotoxins and recombinant microbial antigens.

What is a toxoid ?

Description : What is a toxoid ?

Last Answer : Inactivating the toxin with formaldehyde is toxoid.

Normally at what age vaccination of children begins ?

Description : Normally at what age vaccination of children begins ?

Last Answer : Vaccination of children begins at the age of 2 months.

How is active immunity acquired ?

Description : How is active immunity acquired ?

Last Answer : Active immunity is acquired through vaccines, attenuated organisms, toxoid, natural infection, cloned microbial antigens, etc.

How passive immunity is acquired ?

Description : How passive immunity is acquired ?

Last Answer : Passive immunity is acquired through natural maternal antibodies, antitoxin, and immunoglobulin.