The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin

The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin
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Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of the following statement(s) is/are true concerning intracellular receptors? a. The messengers or hormones must by lipophilic b. These intracellular receptors generally regulate protein synthesis c. The intracellular receptors are located entirely in the nucleus of the cell d. A heat-shock protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor

Description : Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of ... protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor

Last Answer : Answer: a, d Although most hormone and other messenger receptors are extracellular, intracellular receptors have been identified. The hormone messengers involved for these receptors are primarily ... DNA-binding domain of the receptor. Activation involves the dissociation of the inhibitor protein

Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane

Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane

Last Answer : C) production of new proteins

Which statement is NOT true about steroid hormones? A) They include hormones such as estrogen. B) They do not bind to cell surface receptors. C) The hormone-receptor complex can enter the nucleus. D) The hormone-receptor complex can bind to chromatin. E) Steroid hormones act faster than non-steroid (peptide) hormones.

Description : Which statement is NOT true about steroid hormones? A) They include hormones such as estrogen. B) They do not bind to cell surface receptors. C) The hormone-receptor complex can enter the ... complex can bind to chromatin. E) Steroid hormones act faster than non-steroid (peptide) hormones.

Last Answer : E) Steroid hormones act faster than non-steroid (peptide) hormones.

Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the G-protein involve binding and hydrolysis of ATP c. The G protein receptor generates an intracellular messenger commonly through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors

Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C

With regard to membrane receptors for hormones: a. they are often glycoproteins b. they are important for hormones made up of steroid c. those for insulin exhibit an intrinsic protein kinase activity d. glucagon uses calcium as a second messenger

Description : With regard to membrane receptors for hormones: a. they are often glycoproteins b. they are important for hormones made up of steroid c. those for insulin exhibit an intrinsic protein kinase activity d. glucagon uses calcium as a second messenger

Last Answer : they are often glycoproteins

Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the cytoplasm. C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.

Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.

Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.

Which statement about hormone types is correct? A) Non-steroid hormones activate an enzyme cascade. B) Steroid hormones regulate the production of a particular protein. C) Non-steroid hormones are either amino acids, peptides, or proteins. D) Steroid hormones all have four carbon rings with different side chains. E) All of the choices are correct.

Description : Which statement about hormone types is correct? A) Non-steroid hormones activate an enzyme cascade. B) Steroid hormones regulate the production of a particular protein. C) Non-steroid hormones are ... all have four carbon rings with different side chains. E) All of the choices are correct.

Last Answer : E) All of the choices are correct.

Hormone receptors that stimulate cAMP production (A) are part of a complex of two proteins that transform the external signal into internal cAMP production (B) are proteins distinct and separate from those that catalyze the production of cAMP (C) cause release of the catalytic subunit upon binding of the hormone (D) are not very specific and bind a number of different hormones

Description : Hormone receptors that stimulate cAMP production (A) are part of a complex of two proteins that transform the external signal into internal cAMP production (B) are proteins distinct and separate from those ... binding of the hormone (D) are not very specific and bind a number of different hormones

Last Answer : Answer : B

Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s) is/are true concerning these messengers? a. Paracrine regulation involves a messenger which is produced and acts systemically b. The extracellular signal or stimulus is received by a receptor on or in the target cell c. Neurocrine regulation depends on a physical connection between the neuron and the target cell d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane

Description : Cell regulation can be thought of as the effector side of cell communication. Most commonly cell regulation occurs by means of extracellular chemical messengers. Which of the following statement(s ... d. Most hormones, local mediators, and neurotransmitters readily cross the cell plasma membrane

Last Answer : Answer: b, c Depending on how the extracellular messenger arrives, cell regulation can be classified as paracrine, endocrine, or neurocrine. In paracrine regulation, a chemical messenger ... , local mediators, and neurotransmitters are water-soluble and cannot readily cross the plasma membrane

β-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol

Description : β-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol

Last Answer : Answer : C

α-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol

Description : α-Subunits of insulin receptor are present (A) Outside the cell membrane (B) In the cell membrane (C) Across the cell membrane (D) In the cytosol

Last Answer : Answer : A

All the following statements about TSH are true except (A) It is a tropic hormone (B) It acts on para-follicular cells of thyroid glands (C) Its receptors are membrane-bound (D) Its second messenger is cyclic AMP

Description : All the following statements about TSH are true except (A) It is a tropic hormone (B) It acts on para-follicular cells of thyroid glands (C) Its receptors are membrane-bound (D) Its second messenger is cyclic AMP

Last Answer : Answer : B

`Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Description : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Last Answer : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as

Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B-Hormone-receptor Complex; C-Protein (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP (c) A-Steroid Hormone; B-Receptor; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex

Description : Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B- ... ; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex

Last Answer : (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP

How does steroid hormone influence the cellular activities? (a) Using aquaporin channels ‘as second messenger’ (b) Changing the permeability of the cell membrane (c) Binding to DNA and forming a gene-hormone complex (d) Activating cyclic AMP located on the cell membrane

Description : How does steroid hormone influence the cellular activities? (a) Using aquaporin channels ‘as second messenger’ (b) Changing the permeability of the cell membrane (c) Binding to DNA and forming a gene-hormone complex (d) Activating cyclic AMP located on the cell membrane

Last Answer : (c) Binding to DNA and forming a gene-hormone complex

Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY

Description : Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY

Last Answer : Answer : B

All the following statements about steroid hormones are true except (A) They are hydrophobic (B) They require carriers to transport them in circulation (C) Their receptors are intracellular (D) They require cyclic AMP as second messenger

Description : All the following statements about steroid hormones are true except (A) They are hydrophobic (B) They require carriers to transport them in circulation (C) Their receptors are intracellular (D) They require cyclic AMP as second messenger

Last Answer : Answer : D

Which statement is NOT true about non-steroid (peptide) hormones? A) They are derived from peptides, proteins, polypeptides, and derivatives of amino acids. B) They bind to receptors on the cell surface. C) They form cyclic AMP inside the cell. D) They create an enzyme cascade effect. E) They enter the cell in order to have an effect.

Description : Which statement is NOT true about non-steroid (peptide) hormones? A) They are derived from peptides, proteins, polypeptides, and derivatives of amino acids. B) They bind to receptors on the cell surface. ... They create an enzyme cascade effect. E) They enter the cell in order to have an effect.

Last Answer : E) They enter the cell in order to have an effect.

G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins

Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins

Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor

Down regulation is (A) Increased destruction of a hormone (B) Feed back inhibition of hormone secretion (C) Decreased concentration of a hormone in blood (D) Decrease in number of receptors for a hormone

Description : Down regulation is (A) Increased destruction of a hormone (B) Feed back inhibition of hormone secretion (C) Decreased concentration of a hormone in blood (D) Decrease in number of receptors for a hormone

Last Answer : Answer : D

Receptors for thyroid hormones are present (A) On the cell membrane (B) Across the cell membrane (C) Inside the cells (D) In association with G-proteins

Description : Receptors for thyroid hormones are present (A) On the cell membrane (B) Across the cell membrane (C) Inside the cells (D) In association with G-proteins

Last Answer : Answer : C

After entering cytosol, free fatty acids are bound to (A) Albumin (B) Globulin (C) Z-protein (D) None of these

Description : After entering cytosol, free fatty acids are bound to (A) Albumin (B) Globulin (C) Z-protein (D) None of these

Last Answer : Answer : C

Clonal selection includes a. Antigen-receptor binding on B cells. b. Antibody secretion recognizing same epitope as on B cell receptors. c. Differentiation of B cells into plasma cells and memory cells. d. All the above (A—C) are correct.

Description : Clonal selection includes a. Antigen-receptor binding on B cells. b. Antibody secretion recognizing same epitope as on B cell receptors. c. Differentiation of B cells into plasma cells and memory cells. d. All the above (A—C) are correct.

Last Answer : d. All the above (A—C) are correct.

All the following statements about hormones are true except (A) All of them require specific carriers in plasma (B) All of them require specific receptors in target cells (C) Some of them are subject to feedback regulation (D) Some of them increase the transcription of certain genes

Description : All the following statements about hormones are true except (A) All of them require specific carriers in plasma (B) All of them require specific receptors in target cells (C) Some of them are subject to feedback regulation (D) Some of them increase the transcription of certain genes

Last Answer : Answer : A

Steroid hormones are synthesized from (A) Adenine (B) Protein (C) Vitamin (D) Cholesterol

Description : Steroid hormones are synthesized from (A) Adenine (B) Protein (C) Vitamin (D) Cholesterol

Last Answer : Answer : D

Binding of growth hormone to its receptor results in increased transcription of (A) c-fos gene (B) c-myc gene (C) p-53 gene (D) None of these

Description : Binding of growth hormone to its receptor results in increased transcription of (A) c-fos gene (B) c-myc gene (C) p-53 gene (D) None of these

Last Answer : Answer : A

Binding of growth hormone to its receptor results in phosphorylation of (A) JAK-2 (B) Growth hormone receptor (C) STATs (D) All of these

Description : Binding of growth hormone to its receptor results in phosphorylation of (A) JAK-2 (B) Growth hormone receptor (C) STATs (D) All of these

Last Answer : Answer : D

Binding of acetylcholine to its receptors increases the permeability of cell membrane to (A) Ca++ (B) Na+ (C) K+ (D) Na+ and K+

Description : Binding of acetylcholine to its receptors increases the permeability of cell membrane to (A) Ca++ (B) Na+ (C) K+ (D) Na+ and K+

Last Answer : Answer : D

Binding of gamma-aminobutyric acid to its receptors in brain increases the permeability of cell membrane to (A) Cl– (B) Na+ (C) K+ (D) Ca++

Description : Binding of gamma-aminobutyric acid to its receptors in brain increases the permeability of cell membrane to (A) Cl– (B) Na+ (C) K+ (D) Ca++

Last Answer : Answer : A

SRP receptors involved in protein export are present on (A) Ribosomes (B) Endoplasmic reticulum (C) Golgi appartus (D) Cell membrane

Description : SRP receptors involved in protein export are present on (A) Ribosomes (B) Endoplasmic reticulum (C) Golgi appartus (D) Cell membrane

Last Answer : Answer : B

Hormone receptors possess all the following properties except (A) All of them are proteins (B) They possess a recognition domain (C) They bind hormones with a high degree of specificity (D) Number of receptors in a target cell is constant

Description : Hormone receptors possess all the following properties except (A) All of them are proteins (B) They possess a recognition domain (C) They bind hormones with a high degree of specificity (D) Number of receptors in a target cell is constant

Last Answer : Answer : D

Retinol and Retinol binding protein are bound with this protein: (A) Albumin (B) Prealbumin (C) α-globulin (D) β-globulin

Description : Retinol and Retinol binding protein are bound with this protein: (A) Albumin (B) Prealbumin (C) α-globulin (D) β-globulin

Last Answer : Answer : B

Retinol and retinol –binding protein (RBP) bound with this protein: (A) Albumin (B) Prealbumin (C) α2-globulin (D) β-globulin

Description : Retinol and retinol –binding protein (RBP) bound with this protein: (A) Albumin (B) Prealbumin (C) α2-globulin (D) β-globulin

Last Answer : Answer : B

Retinol is transported in blood bound to (A) Aporetinol binding protein (B) α2-Globulin (C) β-Globulin (D) Albumin

Description : Retinol is transported in blood bound to (A) Aporetinol binding protein (B) α2-Globulin (C) β-Globulin (D) Albumin

Last Answer : Answer : A

Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Description : Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Last Answer : C. Tyrosine protein kinase receptors

Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Description : Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of: A. G-protein coupled receptors B. Intrinsic ion channel containing receptors C. Tyrosine protein kinase receptors D. Receptors regulating gene expression

Last Answer : C. Tyrosine protein kinase receptors

Steroid hormones easily pass through plasma membrane by simple diffusions because by

Description : Steroid hormones easily pass through plasma membrane by simple diffusions because by

Last Answer : Steroid hormones easily pass through plasma membrane by simple diffusions because by A. Are lipid- ... through pores D. Contains carbon and hydrogen

Which of the following statement is correct about membrane cholesterol? (A) The hydroxyl group is located near the centre of the lipid layer (B) Most of the cholesterol is in the form of a cholesterol ester (C) The steroid nucleus form forms a rigid, planar structure (D) The hydrocarbon chain of cholesterol projects into the extracellular fluid

Description : Which of the following statement is correct about membrane cholesterol? (A) The hydroxyl group is located near the centre of the lipid layer (B) Most of the cholesterol is in the form ... forms a rigid, planar structure (D) The hydrocarbon chain of cholesterol projects into the extracellular fluid

Last Answer : C

Binding of thyroxine to its receptors (A) Activates Adenylate cyclase (B) Activates guanylate cyclase (C) Activates a stimulatory G-protein (D) Increases transcription

Description : Binding of thyroxine to its receptors (A) Activates Adenylate cyclase (B) Activates guanylate cyclase (C) Activates a stimulatory G-protein (D) Increases transcription

Last Answer : Answer : D

Which of the following is NOT correct about hormones? A) Hormones are generally found across the animal kingdom. B) Hormones may be used at a distance from where the hormone is made. C) Hormones have a slower effect than that mediated by the nervous system. D) Hormones bind to receptor sites at a target cell. E) Hormones are directed to the target organ and avoid contact with non-target cells.

Description : Which of the following is NOT correct about hormones? A) Hormones are generally found across the animal kingdom. B) Hormones may be used at a distance from where the hormone is made. C) ... target cell. E) Hormones are directed to the target organ and avoid contact with non-target cells.

Last Answer : E) Hormones are directed to the target organ and avoid contact with non-target cells.

The followings are steroid hormones: a. corticotrophic hormone (ACTH) b. aldosterone c. thyroxine d. growth hormone

Description : The followings are steroid hormones: a. corticotrophic hormone (ACTH) b. aldosterone c. thyroxine d. growth hormone

Last Answer : aldosterone

Protein bound iodine is _________ bound to protein. (A) Iodine (B) Thyroid hormones (C) Thyroxine (D) Tri iodo thyronine

Description : Protein bound iodine is _________ bound to protein. (A) Iodine (B) Thyroid hormones (C) Thyroxine (D) Tri iodo thyronine

Last Answer : Answer : B

All the following statements about ACTH are true except (A) It is a tropic hormone (B) Its target cells are located in adrenal cortex (C) Its receptors are located in the cell membrane (D) Its second messenger is inositol triphosphate

Description : All the following statements about ACTH are true except (A) It is a tropic hormone (B) Its target cells are located in adrenal cortex (C) Its receptors are located in the cell membrane (D) Its second messenger is inositol triphosphate

Last Answer : Answer : D

Which of the following ribosomes are engaged in protein synthesis in animal cell? (a) Ribosomes which occur on nuclear membrane and ER (b) Ribosomes of only cytosol (c) Ribosomes of only nucleolus and cytosol (d) Ribosomes of only mitochondria and cytosol

Description : Which of the following ribosomes are engaged in protein synthesis in animal cell? (a) Ribosomes which occur on nuclear membrane and ER (b) Ribosomes of only cytosol (c) Ribosomes of only nucleolus and cytosol (d) Ribosomes of only mitochondria and cytosol

Last Answer : (a) poleward movement

Which of the following receptors does not span the cell membrane 7 times a. β-Adrenergic receptor b. Rhodopsin c. 5-HTic receptor d. Mineralocorticoid receptor

Description : Which of the following receptors does not span the cell membrane 7 times a. β-Adrenergic receptor b. Rhodopsin c. 5-HTic receptor d. Mineralocorticoid receptor

Last Answer : Mineralocorticoid receptor

Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor

Description : Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor

Last Answer : Answer : A

What is correct to say about the hormone action in humans? (a) Glucagon is secreted by β-cells of islets of Langerhans and stimulates glycogenolysis. (b) Secretion of thymosins is stimulated with aging. (c) In females, FSH first binds with specific receptors on ovarian cell membrane. (d) FSH stimulates the secretion of estrogen and progesterone.

Description : What is correct to say about the hormone action in humans? (a) Glucagon is secreted by β-cells of islets of Langerhans and stimulates glycogenolysis. (b) Secretion of thymosins is stimulated ... receptors on ovarian cell membrane. (d) FSH stimulates the secretion of estrogen and progesterone.

Last Answer : (c) In females, FSH first binds with specific receptors on ovarian cell membrane.

What is correct to say about the hormone action in humans ? (1) FSH stimulates the secretion of estrogen and progesterone (2) Glucagon is secreted by -cells of Islets of Langerhans and stimulates glycogenolysis (3) Secretion of thymosins is stimulated with aging (4) If females, FSH first binds with specific receptors on ovarian cell membrane

Description : What is correct to say about the hormone action in humans ? (1) FSH stimulates the secretion of estrogen and progesterone (2) Glucagon is secreted by -cells of Islets of Langerhans and ... stimulated with aging (4) If females, FSH first binds with specific receptors on ovarian cell membrane

Last Answer : (4) If females, FSH first binds with specific receptors on ovarian cell membrane

According to which theory is the given statement correct ? Statement. B and T cells having receptors for self antigens, undergo programmed cell death

Description : According to which theory is the given statement correct ? Statement. B and T cells having receptors for self antigens, undergo programmed cell death

Last Answer : According to which theory is the given statement correct ? Statement. B and T cells having ... C. Wear and tear throry D. Immunological theory

Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus)?(a) Insulin, glucagon (b) Thyroxine, insulin (c) Somatostatin, oxytocin (d) Cortisol, testosterone

Description : Which one of the following pairs of hormones are the examples of those that can easily pass through the cell membrane of the target cell and bind to a receptor inside it (mostly in the nucleus)? (a) Insulin, glucagon (b) Thyroxine, insulin (c) Somatostatin, oxytocin (d) Cortisol, testosterone

Last Answer : (d) Cortisol, testosterone