Description : The most important preformed mediator of allergic reactions is/are a. Prostaglandin b. Interleukin c. Histamine d. Leukotrienes
Last Answer : c. Histamine
Description : Tachyphylaxis to many actions on repeated injection is a feature of the following autacoid: A. Histamine B. 5-Hydroxytryptamine C. Bradykinin D. Prostaglandin E2
Last Answer : B. 5-Hydroxytryptamine
Description : Lipo-oxygenase is required for the synthesis of (A) Prostaglandins (B) Leukotrienes (C) Thromboxanes (D) All of these
Last Answer : Answer : B
Description : Slow reacting Substance of Anaphylaxis is a mixture of (A) Prostaglandins (B) Prostacyclins (C) Thromboxanes (D) Leukotrienes
Last Answer : Answer : D
Description : Anti-inflammatory corticosteroids inhibit the synthesis of (A) Leukotrienes (B) Prostaglandins (C) Thromboxanes (D) All of these
Description : Eicosanoids mediate inflammation in a variety of ways. Of the following statements, which are true with regard to this? a. Eicosanoids are stored in cytoplasmic granules ... include vasodilatation, vasoconstriction, increased vascular permeability and both chemotaxis and chemoattractant inhibition
Last Answer : Answer: b, d The eicosanoids are derived from arachidonic acid (eicosatetraenoic acid) and consist of prostaglandins, thromboxanes, leukotrienes and lipoxins. The eicosanoids are not ... nervous system d. Mononuclear phagocytes release a variety of proinflammatory cytokines and growth factors
Description : Cyclooxygenase-1 and –2 are responsible for (a) The synthesis of prostaglandins from arachidonate (b) The synthesis of leukotrienes from arachidonate (c) The conversion of ATP to cAMP (d) The metabolic degradation of cAMP (e) The conversion of GTP to cGMP
Last Answer : Ans: A
Description : Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in inflammatory processes are produced from arachidonic acid by (a) ... 2 (c) Glutathione - S - transferase (d) Lipoxygenase (e) Phospholipase A2
Last Answer : Ans: B
Description : Explain in brief about leukotrienes and prostaglandins Leukotrienes and prostaglandins are formed only when the mast cell undergo degranulation and enzymatic break down of phospholipids in the plasma membrane ?
Last Answer : The effects produced by them are more pronounced and long lasting than histamine. Leukotrienes mediate mucous production and bronchoconstriction. Prostaglandin D2 causes bronchoconstriction.
Description : Select the nonapeptide which can be generated from plasma globulin by snake venom enzymes, causes fall in BP and intense pain when applied to blister base: A. Kallidin B. Bradykinin C. Angiotensin II D. Angiotensin III
Last Answer : B. Bradykinin
Description : Bradykinin and angiotensin II have the following feature common to both: A. They both cause fall in BP B. They both are degraded by Kininase II C. Their precursor proteins are plasma α2 globulins D. They both release aldosterone from adrenal cortex
Last Answer : C. Their precursor proteins are plasma α2 globulins
Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action
Last Answer : C. It is less liable to cause abrupt first dose hypotension
Description : Captopril pretreatment: A. Inhibits the pressor action of angiotensin I B. Inhibits the pressor action of angiotensin II C. Potentiates the depressor action of bradykinin D. Both ‘A’ and ‘C’ are correct
Last Answer : D. Both ‘A’ and ‘C’ are correct
Description : Ventricular remodeling after myocardial infarction involves the mediation of: A. Angiotensin II B. Prostaglandin C. Bradykinin D. Thromboxane A2
Last Answer : A. Angiotensin II
Description : Angiotensin II plays a key role in the following risk factor for ischaemic heart disease: A. Hypercholesterolemia B. Ventricular hypertrophy C. Carbohydrate intolerance D. Cardiac arrhythmia
Last Answer : B. Ventricular hypertrophy
Description : Angiotensin III is equipotent to angiotensin II in: A. Releasing aldosterone from adrenal cortex B. Promoting Na+ and water reabsorption by direct intrarenal action C. Causing vasoconstriction D. Contracting intestinal smooth muscle
Last Answer : A. Releasing aldosterone from adrenal cortex
Description : Angiotensin II causes rise in blood pressure by: A. Direct vasoconstriction B. Releasing adrenaline from adrenal medulla C. Increasing central sympathetic tone D. All of the above
Last Answer : D. All of the above
Description : Under physiological conditions the rate limiting enzyme in the generation of angiotensin II is: A. Renin B. Angiotensin converting enzyme C. Aminopeptidase D. Angiotensinase
Last Answer : A. Renin
Description : Choose the correct statement about cysteinyl leukotrienes (LT-C4/D4): A. They produce long lasting bronchoconstriction B. They produce sustained rise in blood pressure C. They are responsible ... and sequestrating neutrophils at the site of inflammation D. Their production is inhibited by rofecoxib
Last Answer : A. They produce long lasting bronchoconstriction
Description : Angiotensin converting enzyme inhibitors are contraindicated in: A. High renin hypertensives B. Diabetics C. Congestive heart failure patients D. Pregnant women
Last Answer : D. Pregnant women
Description : The following type of vasodilator is not beneficial in CHF due to systolic dysfunction: A. Calcium channel blocker B. Angiotensin converting enzyme inhibitor C. Nitrate D. Hydralazine
Last Answer : A. Calcium channel blocker
Description : Choose the drug that selectively blocks AT1 subtype of angiotensin receptors: A. Ramipril B. Lovastatin C. Candesartan D. Sumatriptan
Last Answer : C. Candesartan
Description : Clinically, the angiotensin antagonists share the following features of angiotensin converting enzyme inhibitors except: A. Antihypertensive efficacy B. Potential to reverse left ventricular hypertrophy ... of effect on carbohydrate tolerance D. Potential to induce cough in susceptible individuals
Last Answer : D. Potential to induce cough in susceptible individuals
Description : Which of the following statements most closely describes the current status of angiotensin converting enzyme inhibitors in congestive heart failure: A. They are the first choice drugs unless contraindicated B. ... substitute for digitalis D. They are to be used as adjuncts only in resistant cases
Last Answer : D. They are to be used as adjuncts only in resistant cases
Description : Angiotensin converting enzyme inhibitors afford maximum protection against progression of heart failure when used: A. At the higher therapeutic dose range over long term B. At the maximum tolerated dose only till ... restored C. At low doses over long term D. At low doses along with diuretics/digoxi
Last Answer : A. At the higher therapeutic dose range over long term
Description : Angiotensin converting enzyme inhibitors reduce the following haemodynamic parameters in congestive heart failure except: A. Systemic vascular resistance B. Right atrial pressure C. Cardiac output D. Heart rate × pressure product
Last Answer : C. Cardiac output
Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance
Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs
Description : Potentiation of bradykinin appears to play a role in the following effects of angiotensin converting enzyme inhibitors except: A. Fall in BP in the short term B. Fall in BP in the long term C. Cough in susceptible individuals D. Angioedema in susceptible individuals
Last Answer : B. Fall in BP in the long term
Description : The following is a pressor peptide that can be generated both in circulation as well as locally in certain tissues: A. Bradykinin B. Angiotensin C. Kallidin D. Plasmin
Last Answer : B. Angiotensin
Description : Select the receptor that is located intracellularly: A. Opioid μ receptor B. Steroid receptor C. Prostaglandin receptor D. Angiotensin receptor
Last Answer : B. Steroid receptor
Description : The primary mechanism by which prostaglandins promote ulcer healing is: A. Inhibition of gastric acid secretion B. Augmentation of bicarbonate buffered mucus layer covering gastroduodenal mucosa C. Increased bicarbonate secretion in gastric juice D. Increased turnover of gastric mucosal cell
Last Answer : B. Augmentation of bicarbonate buffered mucus layer covering gastroduodenal mucosa
Description : The following class of gastric antisecretory drug also reduce gastric motility and have primary effect on juice volume, with less marked effect on acid and pepsin A. Histamine H2 blockers B. Anticholinergics C. Proton pump inhibitors D. Prostaglandins
Last Answer : B. Anticholinergics
Description : Actions of oxytocin include the following except: A. Vasoconstriction B. Increased water reabsorption in renal collecting ducts C. Contraction of mammary myoepithelium D. Release of prostaglandins from endometrium
Last Answer : A. Vasoconstriction
Description : Montelukast blocks the action of the following autacoid: A. Prostacyclin B. Platelet activating factor C. Leukotriene B4 D. Leukotriene C4/D4
Last Answer : D. Leukotriene C4/D4
Description : Dysmenorrhoea is often associated with excess production of the following autacoid by the endometrium: A. Bradykinin B. Prostaglandin C. Platelet activating factor D. 5-Hydroxytryptamine
Last Answer : B. Prostaglandin
Description : Autacoids differ from hormones in that (a) Autacoids are involved only in the causation of pathological states (b) Autacoids do not have a specific cell/ tissue of origin (c) Autacoids generally act locally at the site of generation and release (d) Both (b) and (c)
Last Answer : Ans: D
Description : Prostaglandin is; B A. Neurotransmitter B. Autacoids C. Endocrine hormone D. Steroid hormone
Last Answer : Autacoids
Description : Autacoids differ from hormones in that: A. Autacoids are involved only in the causation of pathological states B. Autacoids do not have a specific cell/tissue of origin C. Autacoids generally act locally at the site of generation and release D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Green-water in a preformed pond?
Last Answer : Buy some fish that eat algae. I don’t know what kind, but I’m sure they’re out there! XP
Description : In the book of John what was the first miracle Jesus preformed?
Last Answer : At John 2:3-10 it tells us that Jesus was at a wedding and wasable to turn water into wine. Truly we can see the power that hehas on a small scale. Imagine what he will do in the near futurewhen ... forth as a Warrior King as brought out in Rev.19:11-16 and cleanses the earth of all wickedness...
Description : What where some of the miracles that saint rose preformed?
Last Answer : What is the answer ?
Description : Is visiting a university to have your dental work preformed cheaper then visiting a dentist?
Last Answer : Usually it is cheaper because you are going to students of the school, not a certified dentist. The students are overseen by a dentist but you are very much a practice person for the students.
Description : How is cardiopulmonary resuscitation preformed?
Last Answer : You can take a CPR course to get certified in cardiopulmonart resusciation either in person or online. http://www.mayoclinic.com/health/first-aid-cpr/FA00061 tells you the basics of CPR but the best way to make sure you're doing it right is to get certified.
Description : Preformed Vitamin A is supplied by (A) Milk, fat and liver (B) All yellow vegetables (C) All yellow fruits (D) Leafy green vegetables CHAPTER 5 CHAPTER 5 VITAMINS
Last Answer : Answer : A
Description : Following is an example of preformed and not lipid derived mast cell mediator of inflammatory process (a) LTC4 (b) PGD2 (c) PAF (d) Histamine
Description : All of the following are true regarding platelet-activating factor (PAF) EXCEPT: C A. Induces platelet aggregation B. Stimulates platelet secretion C. It is a preformed molecule present in various cells D. None of these
Last Answer : It is a preformed molecule present in various cells
Description : Antivenom injection contains preformed antibodies while polio drops that are administered into the body contain (a) gamma globulin (b) attenuated pathogens (c) activated pathogens (d) harvested antibodies
Last Answer : (b) attenuated pathogens
Description : Loading is with the task of storage management of operating system and mostly preformed after assembly: a. Bound b. Expanded c. Overlaps d. All of these
Last Answer : a. Bound
Description : Assertion `:-` Angiotensin II, activates the adrenall cortex to release aldosterone. Reason `:-` Aldosterone causes reabsorption of `Na^(o+)` and wate
Last Answer : Assertion `:-` Angiotensin II, activates the adrenall cortex to release aldosterone. Reason `:-` ... D. If both Assertion & Reason are false.