Six months after beginning atorvastatin, the patient’s total and LDL cholesterol concentrations remained above normal and he continued to have anginal attacks despite good adherence to his antianginal medications. His physician decided for niacin. The major recognized mechanism of action of niacin is (a) Decreased lipid synthesis in adipose tissue (b) Decreased oxidation of lipids in endothelial cells (c) Decreased secretion of VLDL by the liver (d) Increased endocytosis of HDL by the liver (e) Increased lipid hydrolysis by lipoprotein lipase

Six months after beginning atorvastatin, the patient’s total and LDL cholesterol concentrations remained above normal and he continued to have anginal attacks despite good adherence to his antianginal medications. His physician decided for niacin. The major recognized mechanism of action of niacin is (a) Decreased lipid synthesis in adipose tissue (b) Decreased oxidation of lipids in endothelial cells (c) Decreased secretion of VLDL by the liver (d) Increased endocytosis of HDL by the liver (e) Increased lipid hydrolysis by lipoprotein lipase
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With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.

With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the formation of red blood cell membranes. 3) Chylomicrons are synthesized in the liver. 4) HDL is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.

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Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.

Increased serum levels of which of the following may be associated with a decreased risk of atherosclerosis? (a) Very low-density lipoproteins (VLDL) (b) Low-density lipoproteins (LDL) (c) Intermediate – density lipoproteins (IDL) (d) High-density lipoproteins (HDL) (e) Cholesterol

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After being counseled about lifestyle and dietary changes, the patient was started on atorvastatin. During his treatment with atorvastatin, it is important to routinely monitor serum concentrations of (a) Blood urea nitrogen (BUN) (b) Alanine and aspartate aminotransferase (c) Platelets (d) Red blood cells (e) Uric acid

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Which of the following antianginal drugs is most likely to produce tachycardia as a side effect ? (a) Amlodipine (b) Nifedipine (c) Diltiazem (d) Verapamil

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In patients with chronic granulomatous disease which of the following agents increases the synthesis of tumor necrosis factor, leading to activation of phagocytosis? (a) Aldesleukin (b) Cyclosporine (c) Filgrastim (d) Infliximab (e) Interferon gamma

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Nascent HDL of intestinal origin acquires Apo C and Apo E from (A) Chylomicrons (B) VLDL (C) LDL (D) HDL of the hepatic origin

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Nascent chylomicron receives apolipoproteins C and E from (A) VLDL remnant (B) VLDL (C) LDL (D) HDL

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Fatty acids are a major energy source for the body. Which of the following statement(s) is/are true concerning the use of fatty acids as an energy source? a. Fatty acids are stored in adipocytes as triglycerides b. Hormone-sensitive lipase is present only in adipose tissue c. Fatty acids are released into the circulation traveling freely in plasma d. Approximately 25% of total nonprotein caloric needs supplied via total parenteral nutrition should be in the form of fat

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The following is true of simvastatin except: A. It is more potent than lovastatin B. At the highest recommended dose, it causes greater LDL-cholesterol lowering than lovastatin C. It does not undergo first pass metabolism in liver D. It can raise HDL-cholesterol level when the same is low at base line

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Last Answer : Answer : B

Increase in blood of this class of lipoproteins is beneficial to ward off coronary heart disease: (A) HDL (B) LDL (C) VLDL (D) IDL

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Last Answer : Answer : A

VLDL remnant may be converted into (A) VLDL (B) LDL (C) HDL (D) Chylomicrons

Description : VLDL remnant may be converted into (A) VLDL (B) LDL (C) HDL (D) Chylomicrons

Last Answer : Answer : C

Elevated plasma level of the following projects against atherosclerosis: (A) Chylomicrons (B) VLDL (C) HDL (D) LDL

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Last Answer : Answer : C

The highest phospholipids content is found in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

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Apolipoprotein B-48 is present in (A) Chylomicrons (B) VLDL (C) LDL (D) HDL

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Last Answer : Answer : A

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