Pyruvate kinase requires ______ ions for maximum activity. (A) Na+ (B) K+ (C) Ca2+ (D) Mg2+

Pyruvate kinase requires ______ ions for maximum activity. (A) Na+ (B) K+ (C) Ca2+ (D) Mg2+
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What is the principal cation of intracellular fluid? (A) K+ (B) Na+ (C) Ca2+ (D) Mg2+

Description : What is the principal cation of intracellular fluid? (A) K+ (B) Na+ (C) Ca2+ (D) Mg2+

Last Answer : Answer : A

The exchangeable sodium ratio (ESR) can be calculated as ESR = Exchangeable (C2+ + Mg2+)/Exchangeable Na+ ESR = Exchangeable Na+ / ESR = Exchangeable Na+ / Exchangeable (Ca2+ + K+) ESR = Exchangeable Na+ / Exchangeable (Ca2+ + Mg2+)

Description : The exchangeable sodium ratio (ESR) can be calculated as ESR = Exchangeable (C2+ + Mg2+)/Exchangeable Na+ ESR = Exchangeable Na+ / ESR = Exchangeable Na+ / Exchangeable (Ca2+ + K+) ESR = Exchangeable Na+ / Exchangeable (Ca2+ + Mg2+)

Last Answer : ESR = Exchangeable Na+ / Exchangeable (Ca2+ + Mg2+)

Most bacteria do not require the ion a. Mg2+ b. Ca2+ c. Na+ d. Fe+2

Description : Most bacteria do not require the ion a. Mg2+ b. Ca2+ c. Na+ d. Fe+2

Last Answer : Ans: C

Sodium adsorption ratio (SAR) can be calculated by using of formula (a) SAR = Na+ / (b) SAR = Na+ / (c) SAR = Ca2+ + Mg2+ / (d) SAR = Na+ /

Description : Sodium adsorption ratio (SAR) can be calculated by using of formula (a) SAR = Na+ / (b) SAR = Na+ / (c) SAR = Ca2+ + Mg2+ / (d) SAR = Na+ /

Last Answer : (b) SAR = Na+ /

The enzyme of the glycolic pathway, sensitive to inhibiton by fluoride ions is (A) Hexokinase (B) Aldolase (C) Enolase (D) Pyruvate kinase

Description : The enzyme of the glycolic pathway, sensitive to inhibiton by fluoride ions is (A) Hexokinase (B) Aldolase (C) Enolase (D) Pyruvate kinase

Last Answer : Answer : C

Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in which Na+ and glucose are co-transported (C) Pyruvate kinase catalyses an irreversible reaction (D) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte

Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte

Last Answer : C

The principal cation of extra cellular fluid: (A) K+ (B) Na+ (C) H+ (D) Ca2+

Description : The principal cation of extra cellular fluid: (A) K+ (B) Na+ (C) H+ (D) Ca2+

Last Answer : Answer : B

Insulin increases the activity of (A) Pyruvate kinase (B) Phosphorylase (C) Triacylglycerol kinase (D) Fructose 2, 6-bisphosphatase

Description : Insulin increases the activity of (A) Pyruvate kinase (B) Phosphorylase (C) Triacylglycerol kinase (D) Fructose 2, 6-bisphosphatase

Last Answer : Answer : A

Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase

Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase

Last Answer : Answer : B

Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase

Description : Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase

Last Answer : Answer : B

In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase

Last Answer : Answer : B

The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency

Last Answer : C

One of the following enzymes does not change glycogen synthase a to b. (A) Glycogen synthase kinases 3, 4, 5 (B) Ca2+ calmodulin phosphorylase kinase (C) Ca2+ calmodulin dependent protein kinase (D) Glycogen phosphorylase a

Description : One of the following enzymes does not change glycogen synthase a to b. (A) Glycogen synthase kinases 3, 4, 5 (B) Ca2+ calmodulin phosphorylase kinase (C) Ca2+ calmodulin dependent protein kinase (D) Glycogen phosphorylase a

Last Answer : D

The positive inotropic action of digoxin takes several hours to develop because: A. Binding of digoxin to Na+K+ATPase is slow B. After Na+K+ATPase inhibition by digoxin, Ca2+ loading of myocardial fibres occurs progressively with each contraction C. Digoxin inhibits Na+K+ATPase through modification of gene function which takes time D. Both ‘A’ and ‘B’ are correc

Description : The positive inotropic action of digoxin takes several hours to develop because: A. Binding of digoxin to Na+K+ATPase is slow B. After Na+K+ATPase inhibition by digoxin, Ca2+ loading of myocardial ... +ATPase through modification of gene function which takes time D. Both A' and B' are correc

Last Answer : D. Both ‘A’ and ‘B’ are correct

hat is/are the consequence(s) of myocardial Na+ K+ ATPase inhibition by digoxin: A. Increased intracellular Na+ ion concentration B. Increased cytosolic Ca2+ ion concentration C. Increased intracellular K+ ion concentration D. Both ‘A’ and ‘B’ are correct

Description : hat is/are the consequence(s) of myocardial Na+ K+ ATPase inhibition by digoxin: A. Increased intracellular Na+ ion concentration B. Increased cytosolic Ca2+ ion concentration C. Increased intracellular K+ ion concentration D. Both ‘A’ and ‘B’ are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Insulin increases the permeability of glucose across the plasma membrane of muscle cells by (A) Acting on adenylate cycle (B) By loosening the integrity of the membrane (C) Through Ca2+ ions (D) By membrane cruting the hexose carries of intracellular organelles and making them fuse with the plasma membrane

Description : Insulin increases the permeability of glucose across the plasma membrane of muscle cells by (A) Acting on adenylate cycle (B) By loosening the integrity of the membrane (C) Through Ca2 ... membrane cruting the hexose carries of intracellular organelles and making them fuse with the plasma membrane

Last Answer : Answer : D

Adenylate cyclase is activated by (A) Insulin (B) Glucagon (C) Prostaglandin E1 (D) Ca2+ ions

Description : Adenylate cyclase is activated by (A) Insulin (B) Glucagon (C) Prostaglandin E1 (D) Ca2+ ions

Last Answer : Answer : B

In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : Answer : B

A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase

Description : A gluconeogenic enzyme among the following is (A) Phosphofructokinase (B) Pyruvate kinase (C) Phosphoenol pyruvate carboxykinase (D) Glucokinase

Last Answer : Answer : C

Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase

Description : Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase

Last Answer : Answer : A

An enzyme involved in gluconeogenesis is (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Hexokinase (D) Phosphohexose isomerase

Description : An enzyme involved in gluconeogenesis is (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Hexokinase (D) Phosphohexose isomerase

Last Answer : Answer : B

Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase

Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase

Last Answer : Answer : D

In the glycolytic pathway, enolpyruvate is converted to ketopyruvate by (A) Pyruvate kinase (B) Phosphoenolpyruvate (C) Pyruvate dehydrogenase (D) Spontaneously

Description : In the glycolytic pathway, enolpyruvate is converted to ketopyruvate by (A) Pyruvate kinase (B) Phosphoenolpyruvate (C) Pyruvate dehydrogenase (D) Spontaneously

Last Answer : Answer : D

Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Last Answer : B

The glycolysis is regulated by (A) Hexokinase (B) Phosphofructokinase (C) Pyruvate kinase (D) All of these

Description : The glycolysis is regulated by (A) Hexokinase (B) Phosphofructokinase (C) Pyruvate kinase (D) All of these

Last Answer : D

Which of the following enzymes in Glycolytic pathway is inhibited by fluoride? (A) Glyceraldehyde-3-p dehydrogenase (B) Phosphoglycerate kinase (C) Pyruvate kinase (D) Enolase

Description : Which of the following enzymes in Glycolytic pathway is inhibited by fluoride? (A) Glyceraldehyde-3-p dehydrogenase (B) Phosphoglycerate kinase (C) Pyruvate kinase (D) Enolase

Last Answer : D

In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Description : In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase

Last Answer : C

ATP is ‘wasted’ in Rapoport-Lueberring cycle in RBCs as otherwise it will inhibit (A) Phosphoglucomutase (B) Phosphohexo isomerase (C) Phosphofructo kinase (D) Phosphoenol pyruvate carboxy kinase

Description : ATP is ‘wasted’ in Rapoport-Lueberring cycle in RBCs as otherwise it will inhibit (A) Phosphoglucomutase (B) Phosphohexo isomerase (C) Phosphofructo kinase (D) Phosphoenol pyruvate carboxy kinase

Last Answer : C

Which one of the following is a rate limiting enzyme of gluconeogenesis? (A) Hexokinase (B) Phsophofructokinase (C) Pyruvate carboxylase (D) Pyruvate kinase

Description : Which one of the following is a rate limiting enzyme of gluconeogenesis? (A) Hexokinase (B) Phsophofructokinase (C) Pyruvate carboxylase (D) Pyruvate kinase

Last Answer : C

The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatose (D) Glycerokinase

Description : The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatose (D) Glycerokinase

Last Answer : A

The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Description : The following is an enzyme required for glycolysis: (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Glucose-6-phosphatase (D) Glycerokinase

Last Answer : A

What is pyruvate kinase?

Description : What is pyruvate kinase? 

Last Answer : It catalyses the reaction, phospho enol pyruvate to pyruvate.

If there is one million Mg2+ ions in MgCl2, how many chloride ions are there? (1) Two million (2) One million (3) Half a million (4) Ten million

Description : If there is one million Mg2+ ions in MgCl2, how many chloride ions are there? (1) Two million (2) One million (3) Half a million (4) Ten million

Last Answer : (1) Two million

If Mg Cl2 contains one Millions of Mg2+ Ions, then how many Chloride Ions are present in it?

Description : If Mg Cl2 contains one Millions of Mg2+ Ions, then how many Chloride Ions are present in it?

Last Answer : Two million

Catalytic activity of salivary amylase requires the presence of (A) Chloride ions (B) Bromide ions (C) Iodide ions (D) All of these

Description : Catalytic activity of salivary amylase requires the presence of (A) Chloride ions (B) Bromide ions (C) Iodide ions (D) All of these

Last Answer : A

Na+/K+-ATPase along with ATP requires (A) Ca (B) Mn (C) Mg (D) Cl

Description : Na+/K+-ATPase along with ATP requires (A) Ca (B) Mn (C) Mg (D) Cl

Last Answer : Answer : C

The enzyme carbamoyl phosphate synthetase requires (A) Mg++ (B) Ca++ (C) Na+ (D) K+

Description : The enzyme carbamoyl phosphate synthetase requires (A) Mg++ (B) Ca++ (C) Na+ (D) K+

Last Answer : Answer : A

The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes and inhibit bacterial protein synthesis (c) They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

Description : The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes ... peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

Last Answer : Ans: B

Ions moving towards the cathode during electrolysis of an aqueous solution of Ca(OH)2 are (a) OH (b) H+ (c) Ca2+ (d) 02

Description : Ions moving towards the cathode during electrolysis of an aqueous solution of Ca(OH)2 are (a) OH (b) H+ (c) Ca2+ (d) 02

Last Answer : Ans:(a)

The most important mechanism by which tetracycline antibiotics exert antimicrobial action is: A. They chelate Ca2+ ions and alter permeability of bacterial cell membrane B. They bind to 30S ribosomes and inhibit bacterial protein synthesis C. They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria D. They interfere with DNA mediated RNA synthesis in bacteria

Description : The most important mechanism by which tetracycline antibiotics exert antimicrobial action is: A. They chelate Ca2+ ions and alter permeability of bacterial cell membrane B. They bind to 30S ribosomes ... peptide chain in the bacteria D. They interfere with DNA mediated RNA synthesis in bacteria

Last Answer : B. They bind to 30S ribosomes and inhibit bacterial protein synthesis

Sodium valproate has been shown to: A. Prolong neuronal Na+ channel inactivation B. Attenuate ‘T’ type Ca2+ current in neurones C. Inhibit degradation of GABA by GABA-transaminase D. All of the above

Description : Sodium valproate has been shown to: A. Prolong neuronal Na+ channel inactivation B. Attenuate ‘T’ type Ca2+ current in neurones C. Inhibit degradation of GABA by GABA-transaminase D. All of the above

Last Answer : D. All of the above

The most probable mechanism of anticonvulsant action of phenytoin is: A. Facilitation of GABAergic inhibitory transmission B. Hyperpolarization of neurones C. Interaction with Ca2+ channels to promote Ca2+ influx D. Prolongation of voltage sensitive neuronal Na+ channel inactivation

Description : The most probable mechanism of anticonvulsant action of phenytoin is: A. Facilitation of GABAergic inhibitory transmission B. Hyperpolarization of neurones C. Interaction with Ca2+ channels to promote Ca2+ influx D. Prolongation of voltage sensitive neuronal Na+ channel inactivation

Last Answer : D. Prolongation of voltage sensitive neuronal Na+ channel inactivation

Which of the following is strongly-acidic cation? a.Ba2+ b. Ca2+ c.Ti4+ d. Na+

Description : Which of the following is strongly-acidic cation? a.Ba2+ b. Ca2+ c.Ti4+ d. Na+

Last Answer : c.Ti4+

Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Description : Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Last Answer : C. Blocking Na+ channels

Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Description : Tetrodotoxin blocks nerve impulse/junctional transmission by: A. Anticholinergic action B. Depleting acetylcholine C. Blocking Na+ channels D. Blocking Ca2+ channels

Last Answer : C. Blocking Na+ channels

For the activity of amylase which of the following is required as co-factor? (A) HCO3 (B) Na+ (C) K+ (D) Cl

Description : For the activity of amylase which of the following is required as co-factor? (A) HCO3 (B) Na+ (C) K+ (D) Cl

Last Answer : Answer : D

Covalent modification of an enzyme generally requires a (A) Hormone (B) cAMP (C) Protein kinase (D) All of these

Description : Covalent modification of an enzyme generally requires a (A) Hormone (B) cAMP (C) Protein kinase (D) All of these

Last Answer : Answer : D

Pyruvate kinase deficiency?

Description : Pyruvate kinase deficiency?

Last Answer : DefinitionPyruvate kinase deficiency is an inherited lack of the enzyme pyruvate kinase, which is used by red blood cells. Without this enzyme, red blood cells break down too easily, resulting in ... However, certain populations, such as the Amish, are somewhat more likely to develop the conditi

There are two properties of the cell necessary to maintain nonequilibrium cellular composition; the first is selectivity and the second is energy conversion. Which of the following statement(s) is/are true concerning energy converting transport? a. The site of energy conversion and transport in the plasma membrane involves the phospholipid component b. The Na+-K++-ATPase derives energy from hydrolysis of extracellular ATP c. In some systems, energy inherent in the transmembrane ion gradient can be used to drive transport of a second species d. Examples of species transported via secondary active transport include hydrogen ions, calcium, amino acids and glucose

Description : There are two properties of the cell necessary to maintain nonequilibrium cellular composition; the first is selectivity and the second is energy conversion. Which of the following statement(s ... transported via secondary active transport include hydrogen ions, calcium, amino acids and glucose

Last Answer : Answer: c, d The selectivity of the plasma membrane, although impressive, cannot account for the nonequilibrium composition of living cells. A cell can be maintained in a nonequilibrium state only by ... to drive the transport of a second species such as protons, calcium, amino acids, or glucose