Description : Her’s disease is characterized by deficiency of (A) Muscle phosphorylase (B) Liver phosphorylase (C) Debranching enzyme (D) Glycogen synthase
Last Answer : Answer : B
Description : Cori disease (Limit dextrinosis) is caused due to absence of (A) Branching enzyme (B) Debranching enzyme (C) Glycogen synthase (D) Phosphorylase
Description : Cyclic AMP binds to (A) Catalytic subunits of protein kinase (B) Regulatory subunits of protein kinase (C) Catalytic subunits of phosphorylase kinase (D) Regulatory subunits of phosphorylase kinase
Description : Insulin increases the activity of (A) Pyruvate kinase (B) Phosphorylase (C) Triacylglycerol kinase (D) Fructose 2, 6-bisphosphatase
Last Answer : Answer : A
Description : A molecule of phosphorylase kinase is made up of (A) 4 subunits (B) 8 subunits (C) 12 subunits (D) 16 subunits
Last Answer : Answer : D
Description : Pyruvate kinase requires ______ ions for maximum activity. (A) Na+ (B) K+ (C) Ca2+ (D) Mg2+
Last Answer : B
Description : Insulin decreases the activity of (A) cAMP dependent protein kinase (B) HMG CoA-reductas (C) Phosphodiesterase (D) Acetyl CoA-carboxylase
Description : Adipose tissue lacks (A) Hormone-sensitive lipase (B) Glycerol kinase (C) cAMP-dependent protein kinase (D) Glycerol-3-phosphate dehydrogenase
Description : After the action of phosphorylase, glycogen is converted into (A) Amylopectin (B) dextrin (C) Amylose (D) Maltose
Description : Glycogen phosphorylase liberates the following from glycogen (A) Glucose (B) Glucose-6-phosphate (C) Glucose-1-phosphate (D) Maltose
Last Answer : Answer : C
Description : Pyridoxal phosphate is a coenzyme for (A) Glycogen synthetase (B) Phosphorylase (C) Both (A) and (B) (D) None of these
Description : Glycogen while being acted upon by active phosphorylase is converted first to (A) Glucose (B) Glucose 1-phosphate and Glycogen with 1 carbon less (C) Glucose-6-phosphate and Glycogen with 1 carbon less (D) 6-Phosphogluconic acid
Last Answer : C
Description : Glycogen is converted to glucose-1- phosphate by (A) UDPG transferase (B) Branching enzyme (C) Phosphorylase (D) Phosphatase
Description : What will activate glycogen phosphorylase?
Last Answer : Epinephrine, glucagon, cyclic AMP.
Description : Pompe ’s d isease is caused due to deficiency of (A) Lysosomal α-1→4 and 1→6-glucosidase (B) Glucose-6-phosphatase (C) Glycogen synthase (D) Phosphofructokinase
Description : The hormone activating the glycogen synthase activity is (A) Insulin (B) Glucagon (C) Epinephrine (D) ACTH
Description : Action of glycogen synthase is inhibited by (A) Insulin (B) Glucose (C) Mg2+ (D) Cyclic AMP
Description : Allosteric activator of glycogen synthase is (A) Glucose (B) Glucose-6-Phosphate (C) UTP (D) Glucose-1-phosphate
Description : In glycogenesis a branch point in the molecule is established by the enzyme (A) Amylo[1→ 4][1→ 6] transglucosidase (B) α [1→ 4] α [1→ 4] Glucan transferase (C) Amylo [1→ 6] glucosidase (D) Glycogen synthase
Description : A regulator of the enzyme Glycogen synthase is (A) Citric acid (B) 2, 3 bisphosphoglycerate (C) Pyruvate (D) GTP
Description : One of the following statement is correct: (A) Glycogen synthase ‘a’ is the phosphorylated (B) cAMP converts glycogen synthase b to ‘a’ (C) Insulin converts glycogen synthase b to a (D) UDP glucose molecules interact and grow into a Glycogen tree
Description : The activity of cyclin-dependent kinases (CDks) rises and falls. Why?
Last Answer : •The activity of cyclins and Cdks fluctuates during the cell cycle, molecularly, it either receives a message to go ahead or not to go ahead.
Description : Multiple checkpoints in the eukaryotic cell cycle ensure that division occurs only after sufficient growth and faithful DNA replication, and only when favorable conditions exist. Of the many proteins involved in ... CDKs) are among the most important. How do CDKs function to control the cell cycle?
Last Answer : CDKs phosphorylate various protein substrates that are required for cell cycle progression. Some of the important substrate proteins that CDKs phosphorylate include condensin proteins, which are essential ... which form a stabilizing network under the nuclear membrane that assembles during mitosis.
Description : The region of DNA known as TATA BOX is the site for binding of (A) DNA polymerase (B) DNA topoisomerase (C) DNA dependent RNA polymerase (D) Polynucleotide phosphorylase
Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase
Last Answer : (B) Phosphorylase
Description : In conversion of lactic acid to glucose, three reactions of glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase
Description : Which of the following enzymes incorporates inorganic phosphate into the substrate? (A) Phosphoglycerate kinase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Enolase
Description : The glycerol for fatty acid esterification in adipocytes is (A) For the most part, derived from glucose (B) Obtained primarily from phosphorylation of glycerol by glycerol kinase (C) Formed from gluconeogenesis (D) Formed from glycogenolysis ENZYMES 153
Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase
Description : Which of the following enzymes in Glycolytic pathway is inhibited by fluoride? (A) Glyceraldehyde-3-p dehydrogenase (B) Phosphoglycerate kinase (C) Pyruvate kinase (D) Enolase
Last Answer : D
Description : In conversion of Lactic acid to Glucose, three reactions of Glycolytic pathway are circumvented, which of the following enzymes do not participate? (A) Pyruvate Carboxylase (B) Phosphoenol pyruvate carboxy kinase (C) Pyruvate kinase (D) Glucose-6-phosphatase
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : Which metal is required for the action of Kinases?
Last Answer : Magnesium.
Description : In fatty acids synthase of both bacteria and mammals, ACP (acyl carrier protein) contain the vitamin: (A) Thiamin (B) Pyridoxine (C) Riboflavin (D) Pantothenic acid
Description : The protein, which is in fact a multifunctional enzyme complex in higher organism is (A) Acetyl transacylase (B) Malonyl transacylase (C) 3-Hydroxy acyl-ACP dehyratase (D) Fatty acid synthase
Description : The following is true of loperamide except: A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action B. It acts on the opioid receptors in the gut C. It increases ... of the intestines D. It inhibits intestinal secretion by binding to calmodulin in the mucosal cells
Last Answer : A. It is absorbed from intestines and exerts centrally mediated antidiarrhoeal action
Description : Activated phospholipase C acts on (A) Phosphatidyl inositol-4, 5-biphosphate (B) Inositol-1, 4, 5-triphosphate (C) Protein kinase C (D) Pl-3 kinase
Description : The protein IRS-1 is phosphorylated by (A) Protein kinase A (B) Protein kinase C (C) Tyrosine kinase activity of insulin receptor (D) Tyrosine kinase activity of IGF-1 receptor
Description : Vasoconstrictor effect of ADH is mediated by (A) cAMP (B) cGMP (C) Protein kinase C (D) Angiotensin II
Description : All the following statements about epidermal growth factor are true except (A) It is a protein (B) It possess quaternary structure (C) Its receptor is made up of a single polypeptide chain (D) Its receptor possesses tyrosine kinase domain
Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate
Description : Covalent modification of an enzyme generally requires a (A) Hormone (B) cAMP (C) Protein kinase (D) All of these
Description : The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes ... peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria
Last Answer : Ans: B
Description : The most important mechanism by which tetracycline antibiotics exert antimicrobial action is: A. They chelate Ca2+ ions and alter permeability of bacterial cell membrane B. They bind to 30S ribosomes ... peptide chain in the bacteria D. They interfere with DNA mediated RNA synthesis in bacteria
Last Answer : B. They bind to 30S ribosomes and inhibit bacterial protein synthesis
Description : The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly ... of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger
Last Answer : Answer: a, b The prototypic intracellular messenger is cAMP. To function as a mediator, the concentration of cAMP must change rapidly. In resting cells, cAMP is continuously being degraded by ... produce cGMP. Intracellular calcium ions also serve as second messengers in a large number of cells
Description : Insulin increases (A) Protein synthesis (B) Fatty acid synthesis (C) Glycogen synthesis (D) All of these
Description : Acyl carrier protein is involved in the synthesis of (A) protein (B) glycogen (C) fatty acid outside the mitochondria (D) fatty acid in the mitochondria
Description : Glycogenin is (A) Uncoupler of oxidative phosphorylation (B) Polymer of glycogen molecules (C) Protein primer for glycogen synthesis (D) Intermediate in glycogen breakdown
Description : Oxidation of which substance in the body yields the most calories (A) Glucose (B) Glycogen (C) Protein (D) Lipids