The positive inotropic action of digoxin takes several
hours to develop because:
A. Binding of digoxin to Na+K+ATPase is slow
B. After Na+K+ATPase inhibition by digoxin,
Ca2+ loading of myocardial fibres occurs
progressively with each contraction
C. Digoxin inhibits Na+K+ATPase through modification of gene function which takes time
D. Both ‘A’ and ‘B’ are correc
hours to develop because:
A. Binding of digoxin to Na+K+ATPase is slow
B. After Na+K+ATPase inhibition by digoxin,
Ca2+ loading of myocardial fibres occurs
progressively with each contraction
C. Digoxin inhibits Na+K+ATPase through modification of gene function which takes time
D. Both ‘A’ and ‘B’ are correc