Sodium valproate has been shown to: A. Prolong neuronal Na+ channel inactivation B. Attenuate ‘T’ type Ca2+ current in neurones C. Inhibit degradation of GABA by GABA-transaminase D. All of the above

Sodium valproate has been shown to:
A. Prolong neuronal Na+ channel inactivation
B. Attenuate ‘T’ type Ca2+ current in neurones
C. Inhibit degradation of GABA by GABA-transaminase
D. All of the above
by

1 Answer

Answer :

D. All of the above
by

Related questions

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Last Answer : D. Prolongation of voltage sensitive neuronal Na+ channel inactivation

Select the correct statement about benzodiazepines (BZDs): A. All BZDs facilitate GABA mediated Cl¯ influx into neurones B. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant actions C. The BZD receptor is homogeneous at all neuronal sites D. The muscle relaxant action of BZDs is not blocked by flumazenil

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e primary mechanism by which general anaesthetics produce their action is: A. Affecting receptor operated ion channels in cerebral neurones B. Blocking voltage sensitive Na+ channels in neuronal membrane C. Depressing metabolic activity of cerebral neurones D. Blocking production of high energy phosphates in the brain

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The following is not true of local anaesthetics: A. The local anaesthetic is required in the unionized form for penetrating the neuronal membrane B. The local anaesthetic approaches its receptor only from the intraneuronal face of the Na+ channel C. The local anaesthetic binds to its receptor mainly when the Na+ channel is in the resting state D. The local anaesthetic combines with its receptor in the ionized cationic form

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hat is/are the consequence(s) of myocardial Na+ K+ ATPase inhibition by digoxin: A. Increased intracellular Na+ ion concentration B. Increased cytosolic Ca2+ ion concentration C. Increased intracellular K+ ion concentration D. Both ‘A’ and ‘B’ are correct

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The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is (a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane (b) They bind to 30S ribosomes and inhibit bacterial protein synthesis (c) They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria (d) They interfere with DNA mediated RNA synthesis in bacteria

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Last Answer : D. Both B and C are correct

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Which of the following statements is not true of zopiclone: A. It is a nonbenzodiazepine hypnotic with efficacy and safety similar to benzodiazepines B. It does not produce rebound sleep disturbances on discontinuation C. It does not act by potentiating GABA D. It is used to wean off insomniacs from regular benzodiazepine use

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