Description : Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase
Last Answer : Answer : B
Description : Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase
Last Answer : Answer : A
Description : Which one of the following statements concerning glucose-6-phosphate dehydrogenase deficiency is correct? (A) Young R.B.Cs, particularly reticulocytes, contain the highest enzyme activity cells show less enzyme ... PD gene (D) G-6-PD deficiency is precipitated by ingestion of drugs such as aspirin
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Last Answer : B
Description : Of the following hemolytic anemias, which is categorized as inherited? a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia. b ... is an acquired anemia. d) Hypersplenism Hypersplenism results in an acquired hemolytic anemia.
Last Answer : a) Sickle cell anemia Glucose 6-phosphate dehydrogenase deficiency is an inherited abnormality resulting in hemolytic anemia.
Description : The “Primaquin sensitivity types of haemolytic anaemia has been found to relate to reduced R.B.C activity of which enzyme? (A) Pyruvate kinase deficiency (B) Glucose-6-phosphatase deficiency (C) Glucose-6-p dehydrogenase deficiency (D) Hexokinase deficiency
Last Answer : C
Description : Which of the following enzyme is not involved in HMP shunt? (A) Glyceraldehyde-3-p dehydrogenase (B) Glucose-6-p-dehydrogenase (C) Transketolase (D) Phosphogluconate dehydrogenase
Last Answer : A
Description : Dietary deficiency of thiamin inhibits the activity of the enzyme: (A) Pyruvate kinase (B) Pyruvate dehydrogenase (C) Phosphofructokinase (D) Enolase
Description : The rate of citric acid cycle is controlled by the allosteric enzyme: (A) Aconitase (B) Fumarase (C) Fumarase (D) Malate dehydrogenase
Last Answer : Answer : C
Description : In TCA cycle, oxalosuccinate is converted to α-ketoglutarate by the enzyme: (A) Fumarase (B) Isocitrate dehydrogenase (C) Aconitase (D) Succinase
Description : An allosteric enzyme responsible for controlling the rate of T.C.A cycle is (A) Malate dehydrogenase (B) Isocitrate dehydrogenase (C) Fumarase (D) Aconitase
Description : Folate deficiency causes (A) Microcytic anemia (B) Hemolytic anemia (C) Iron deficiency anemia (D) Megaloblastic anemia
Last Answer : Answer : D
Description : In the TCA cycle, at which of the following enzyme-catalyzed steps, incorporation of elements of water into an intermediate of the cycle takes place : (A) Citrate synthase (B) Aconitase (C) Maleate dehydrogenase (D) Succinyl Co-A synthase
Last Answer : (C) Maleate dehydrogenase
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Last Answer : (D) Megaloblastic anemia
Description : In citric acid cycle, GDP is phosphorylated by (A) Succinate dehydrogenase (B) Aconitase (C) Succinate thiokinase (D) Fumarse
Description : Fluoride inhibits ______ and arrests glycolysis. (A) Glyceraldehyde-3-phosphate dehydrogenase (B) Aconitase (C) Enolose (D) Succinate dehydrogenase
Description : Substrate level phosphorylation in TCA cycle is in step: (A) Isocitrate dehydrogenase (B) Malate dehydrogenase (C) Aconitase (D) Succinate thiokinase
Last Answer : D
Description : A mitochondrial marker enzyme is (A) Aldolase (B) Amylase (C) Succinic dehydrogenase (D) Pyruvate dehydrogenase ENZYMES 175
Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase
Description : In glycolytic pathway, iodacetate inhibits the activity of the enzyme: (A) Phosphotriose isomerase (B) Glyceraldehyde-3-phosphate dehydrogenase (C) Pyruvate kinase (D) Phosphofructokinase
Description : NADPH is produced when this enzyme acts (A) Pyruvate dehydrogenase (B) Malic enzyme (C) Succinate dehydrogenase (D) Malate dehydrogenase
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Description : In pentose phosphate pathway, D-ribulose5-phosphate is converted to D-ribose-5- phosphate by the enzyme: (A) Fumarase (B) Ketoisomerase (C) G-6-PD (D) Epimerase
Description : do Fava beans need to be staked
Last Answer : Need Answer
Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase
Description : Albinism is due to deficiency of the enzyme: (A) Phenylalanine hydroxylase (B) Tyrosinase (C) p-Hydroxyphenylpyruvic acid oxidase (D) Tyrosine dehydrogenase
Description : In acute pancreatitis, the enzyme raised in first five days is (A) Serum amylase (B) Serum lactic dehydrogenase (C) Urinary lipase (D) Urinary amylase
Description : The enzyme of the glycolic pathway, sensitive to inhibiton by fluoride ions is (A) Hexokinase (B) Aldolase (C) Enolase (D) Pyruvate kinase
Description : Acute hemolytic episode after administration of antimalarial drug is due to what?
Last Answer : Deficiency of glucose-6-phosphate dehydrogenase.
Description : An enzyme of pyrimidine nucleotide biosynthesis sensitive to allosteric regulation is (A) Aspartate transcarbamoylase (B) Dihydroorotase (C) Dihydroorotate dehydrogenase (D) Orotidylic acid decarboxylase
Description : The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma
Description : Immediate direct Vanden Bergh reaction indicates (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Megalobastic anemia
Description : An important finding of Fabry’s disease is (A) Skin rash (B) Exophthalmos (C) Hemolytic anemia (D) Mental retardation
Description : The pH of gastric juice become low in (A) Hemolytic anemia (B) Pernicious anemia (C) Both (A) and (B) (D) None of these
Description : Use of the following antimalarial drug carries high risk of adverse effect in subjects with G-6-PD deficiency: A. Pyrimethamine B. Artemisinin C. Primaquine D. Mefloquine
Last Answer : C. Primaquine
Description : Transketolase activity is affected in (A) Bitoin deficiency (B) Pyridoxine deficiency (C) PABA deficiency (D) Thiamine deficiency
Description : Transketolase activity is affected in (A) Biotin deficiency (B) Pyridoxine deficiency (C) PABA deficiency (D) Thiamine deficiency
Description : Transketolase activity is decreased in the deficiency what?
Last Answer : Thiamine pyrophosphate (TPP).
Description : Orotic aciduria type II reflects the deficiency of the enzyme: (A) Orotate phosphoribosyl transferase (B) Orotidylate decarboxylase (C) Dihydroorotase (D) Dihydroorotate dehydrogenase
Description : The transketolase enzyme in the pentose phosphate pathway requires the B vitamin. (A) Pantothenic acid (B) Thiamin (C) Riboflavin (D) Nicotinic acid
Description : What is the clinical significance of transketolase enzyme?
Last Answer : The transketolase reaction is measured in RBCs as an index of the thiamine status of an individual.
Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis
Description : A specific BRCA1 cancer-predisposing gene mutation seems to occur more frequently among women of which descent? a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of ... of treatment for tuberculosis) are at significantly increased risk for developing isoniazid-induced hepatitis.
Last Answer : a) Ashkanazi Jewish Expression of the BRCA1 gene is an example of inheritance in the development of breast cancer.
Description : Hemolytic anemia?
Last Answer : DefinitionHemolytic anemiais a condition in which there are not enough red blood cells in the blood, due to the premature destruction of red blood cells. There are a number of specific types of hemolytic ... cells. The defect may be in the red blood cell itself (intrinsic factors), or outside the
Description : Immune hemolytic anemia?
Last Answer : DefinitionImmune hemolytic anemia is a condition in which there is a reduced blood cell count due to the premature destruction of red blood cells by the immune system.Alternative NamesAnemia - immune ... to certain infectionsIf the cause of antibody formation is a disease or medication, it is refe
Description : Erythroblastosis fetalis and neonatal hemolytic anemia are caused by a maternal immune response to which fetal blood group antigen: A A. Rh B. P C. MN D. None of these
Last Answer : Rh
Description : Pyruvate dehydrogenase contains all except (A) Biotin (B) NAD (C) FAD (D) CoA
Description : Pyruvate dehydrogenase is a/an (A) Isomerase (B) Lyase (C) Ligase (D) Oxido reductase
Description : Thiamine is essential for (A) Pyruvate dehydrogenase (B) Isocitrate dehydrogenase (C) Succinate dehydrogenase (D) Acetyl CoA synthetase ENZYMES 165