If a fibrinolytic drug is used for treatment of acute myocardial infarction, the adverse drug effect that is most likely to occur is (a) Acute renal failure (b) Development of antiplatelet antibodies (c) Encephalitis secondary to liver dysfunction (d) Hemorrhagic stroke (e) Neutropenia

1 Answer

Answer :

Ans: D

Related questions

Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/ ... (a) Sublingual (b) Oral (c) Intravenous bolus injection (d) Slow intravenous infusion

Last Answer : Ans: D

Description : Lidocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because (a) It has a rapidly developing and titratable antiarrhythmic action (b) It casues ... efficacy in atrial as well as ventricular arrhythmias (d) Both (a) and (b)

Last Answer : Ans: D

Description : Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension ... (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia

Last Answer : Ans: E

Description : What drug is used to prevent embolism in the lung and during myocardial infarction? (a) Alteplase (b) Human growth hormone (c) Granulocyte–macrophage colony – stimulating factor (GM–CSF) (d) EPOGEN (EPO) (e) None of the above

Last Answer : Ans: A

Description : Vasodilators are used to treat: A. Acute heart failure attending myocardial infarction B. Chronic heart failure due to diastolic dysfunction C. Chronic heart failure due to both systolic as well as diastolic dysfunction D. All of the above

Last Answer : D. All of the above

Description : Higher incidence of myocardial infarction and increased mortality has been noted with the use of the following antihypertensive drug (a) Nifedipine (b) Verapamil (c) Diltiazem (d) Lisinopril

Last Answer : Ans: A

Description : Indications for the use of antiplatelet drugs include the following except: A. Secondary prophylaxis of myocardial infarction B. Unstable angina pectoris C. Disseminated intravascular coagulation D. Stroke prevention in patients with transient ischaemic attacks

Last Answer : C. Disseminated intravascular coagulation

Description : When digoxin is used in a patient with congestive heart failure (CHF), it works by exerting a positive effect on (a) Stroke volume (b) Total peripheral resistance (c) Heart rate (d) Blood pressure (e) Venous return

Last Answer : Ans: A

Description : Thrombolytic therapy is indicated in the following conditions except: A. Acute myocardial infarction B. Stroke due to cerebral thrombosis C. Deep vein thrombosis D. Large pulmonary embolism

Last Answer : B. Stroke due to cerebral thrombosis

Description : Low dose subcutaneous heparin therapy is indicated for: A. Prevention of leg vein thrombosis in elderly patients undergoing abdominal surgery B. Ischaemic stroke C. Patients undergoing neurosurgery D. Prevention of extention of coronary artery thrombus in acute myocardial infarction

Last Answer : A. Prevention of leg vein thrombosis in eld

Description : In post-myocardial infarction and other high cardiovascular risk subjects but without hypertension or heart failure, prolonged ACE inhibitor medication has been found to: A. Increase the chances of sudden cardiac death ... Lower the risk of developing heart failure and diabetes D. Both B and C'

Last Answer : D. Both ‘B‘ and ‘C

Description : A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route ... suitable: A. Sublingual B. Oral C. Intravenous bolus injection D. Slow intravenous infusion

Last Answer : D. Slow intravenous infusion

Description : Streptokinase is a substance used in the treatment of acute myocardial infarction. How does this substance act?

Last Answer : Substances known as fibrinolytics, like streptokinase and urokinase, can destroy thrombi (clots formed inside blood vessels, capillaries or within the heart chambers) and are used in the treatment ... comes after the bacteria that produce it, the streptococci. Learn the Concept of Homeostasis Here

Description : A patient has developed a sever chest pain and difficulties in breathing while in the dental chair. Your initial response is: a. Administer glycerine trinitrate and monitor patient in upright ... required until confirmed as MI by ECG d. Patient has myocardial infarction as confirmed by ECG

Last Answer : a. Administer glycerine trinitrate and monitor patient in upright position.

Description : A patient has developed a sever chest pain and difficulties in breathing while in the dental chair. Your initial response is: A. Administer glycerine trinitrate and monitor patient in upright ... required until confirmed as MI by ECG D. Patient has myocardial infarction as confirmed by ECG

Last Answer : A. Administer glycerine trinitrate and monitor patient in upright position

Description : In case of acute pain of angina pectoris the most effective treatment would be to administer (a) Mannitol hexanitrate (b) Erythrityl tetranitrate (c) Sodium nitrate (d) Pentaerythritol tetranitrate (e) Nitroglycerin

Last Answer : Ans: E

Description : The following drug is used to reduce the frequency of angina pectoris as well as to terminate an acute attack (a) Digoxin (b) Furosemide (c) Enalapril (d) Amrinone

Last Answer : Ans: A

Description : Myocardial oxygen demand is increased by all of the following factors except (a) Exercise (b) Smoking (c) Cold temperatures (d) Isoproterenol (e) Propranolol

Last Answer : Ans: E

Description : Which of the following cyclotron produced radiopharmaceuticals is used for assessing regional myocardial perfusion as part of an exercise stress test? (a) Thallous chloride 201TI USP (b) Sodium iodide 123I (c) Gallium citrate 67Ga USP (d) Indium 111In pentetate (e) Cobalt 57Co cyanocobalamin

Last Answer : Ans: A

Description : Which of the following statements about septic shock are true? A. A circulating myocardial depressant factor may account for the cardiac dysfunction sometimes seen with shock due to sepsis or ... animal studies that demonstrate a significant improvement in survival with the use of such agents.

Last Answer : Answer: AB DISCUSSION: Shock due to sepsis or SIRS frequently manifests as a hyperdynamic cardiovascular response, consisting of an elevated CI and a decreased SVR or SVRI. Occasionally, ... been encouraging thus far in human clinical trials, despite the promising results from many animal studies

Description : Which of the following is the drug of choice for management of cardiac arrhythmias that occur in digitalis toxicity? (a) Amiodarone (b) Lidocaine (c) Propranolol (d) Sotalol (e) Prazosin

Last Answer : Ans: B

Description : Therapeutic dose of digoxin in a normal individual has the following effects, except (a) Increase in the speed of myocardial contractility (b) No significant change in cardiac output (c) Relaxation of peripheral vascular bed (d) Increase in the force of myocardial contractility

Last Answer : Ans: C

Description : Potential adverse effects associated with aspirin include all of the following except (a) Gastrointestinal ulceration (b) Renal dysfunction (c) Enhanced methotrexate toxicity (d) Cardiac arrhythmias (e) Hypersensitivity asthma

Last Answer : Ans: E

Description :  Prostaglandins play pathophysiological role in the following except: A. Patency of ductus arteriosus B. Regulation of renal tubular salt absorption C. Ventricular remodeling after myocardial infarction D. Initiation of labour

Last Answer : C. Ventricular remodeling after myocardial infarction 

Description : On which day following acute myocardial infarction the estimation of serum AST will be of greatest significance? (A) First day (B) Second day (C) Third day (D) Fourth day

Last Answer : Answer : B

Description : On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value? (A) Serum AST (B) Serum CK (C) Serum ALT (D) Serum LDH

Last Answer : Answer : D

Description : The slow moving fraction of LDH is typically increased in pancreas with (A) Cerebrovascular accidents (B) Acute myocardial infarction (C) Acute pancreatitis (D) Acute viral hepatits

Last Answer : Answer : D

Description : On the third day of onset of acute myocardial infarction the enzyme elevated is (A) Serum AST (B) Serum CK (C) Serum LDH (D) Serum ALT

Last Answer : Answer : C

Description : Serum gamma glutamyl transpeptidase is raised in (A) Haemolytic jaundice (B) Myocardial infarction (C) Alcoholic hepatitis (D) Acute cholecystitis

Last Answer : Answer : C

Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Last Answer : Answer : D

Description : The preferred route of administration of streptokinase in acute myocardial infarction is: A. Intravenous B. Subcutaneous C. Intracoronary

Last Answer : A. Intravenous

Description : Thrombolytic therapy instituted within 3-6 hours of onset of acute myocardial infarction affords the following benefit(s): A. Reduces mortality B. Reduces area of myocardial necrosis C. Preserves ventricular function D. All of the above

Last Answer : D. All of the above

Description : A patient of acute myocardial infarction has been brought to the ICU. What is the time lapse since symptom onset beyond which you will not consider instituting thrombolytic therapy: A. 3 hours B. 6 hours C. 16 hours D. 24 hours

Last Answer : C. 16 hours

Description : Use of anticoagulants in acute myocardial infarction affords the following benefit(s): A. Reduces short-term mortality B. Prevents thrombus extension and subsequent attack C. Prevents venous thromboembolism D. All of the above

Last Answer : C. Prevents venous thromboembolism

Description : Lignocaine is the preferred antiarrhythmic for emergency control of cardiac arrhythmias following acute myocardial infarction because: A. It has a rapidly developing and titratable antiarrhythmic action B. It causes ... atrial as well as ventricular arrhythmias D. Both A' and B' are correct

Last Answer : D. Both ‘A’ and ‘B’ are correct

Description : A hypertensive patient has been using nifedipine for some time without untoward effects. If he experiences a rapidly developing enhancement of the antihypertensive effect of the drug, it is probably due to ... ) Grapefruit juice (d) Induction of drug metabolism (e) Over - the - counter decongestants

Last Answer : Ans: C

Description : When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance

Last Answer : Ans: A

Description : Which of the following antianginal drugs is most likely to produce tachycardia as a side effect ? (a) Amlodipine (b) Nifedipine (c) Diltiazem (d) Verapamil

Last Answer : Ans: B

Description : The agent given sublingually in an acute attack of angina pectoris is (a) Glyceryl trinitrate (b) Amyl nitrite (c) Erythrital tetranitrate (d) Pentaerythritol tetranitrate

Last Answer : Ans: A

Description : Which of the following drugs is a class III antiarrhythmic agent that is effective in the acute management of atrial fibrillation or atrial flutter of recent onset ? (a) Bretylium (b) Lbutilide (c) Metoprolol (d) Disopyramide

Last Answer : Ans: B

Description : Which of the following statement(s) is/are true concerning the diagnosis and management of hypovolemic shock? a. A fall in hematocrit or hemoglobin always accompanies hemorrhagic shock b. The ... d. Complications are less frequent after treatment of hemorrhagic shock than septic or traumatic shock

Last Answer : Answer: d Hypovolemic shock is readily diagnosed when there is an obvious source of volume loss and overt signs of hemodynamic instability and increased adrenergic output are present. ... response systems and consequences of their disseminated, indiscriminate cellular injury can be quite profound

Description : Which of the following statement(s) is/are true concerning the effects of MOFS? a. Pulmonary dysfunction tends to arise early and may resolve within 7 to 10 days b. Unless the precipitating ... infection, most commonly pulmonary, is a common complication providing a second hit to the patient

Last Answer : Answer: a, b, d Pulmonary dysfunction typically arises early in the development of systemic inflammation and may represent mild relatively localized acute lung injury or it may be a prelude ... is marked by progressive rise in serum bilirubin levels after a latent period of several days

Description : Essential amino acids have been advocated as standard therapy for renal failure. Which of the following statements are true? A. Increased survival from acute renal failure has been reported ... BUN and creatinine to the same degree as solutions containing excessive nonessential amino acids.

Last Answer : Answer: BC DISCUSSION: Essential amino acids and hypertonic dextrose, as opposed to hypertonic dextrose alone, was reported by Abel and co-workers to be associated with a decreased mortality rate ... renal failure have not been carried out in sufficient numbers to yield answers to this question

Description : Which of the following is not likely to be the cause of failure of antimicrobial therapy of an acute infection: A. Improper selection of drug and dose B. Acquisition of resistance during treatment C. Failure to drain the pus D. Uncontrolled diabetes mellitus

Last Answer : B. Acquisition of resistance during treatment

Description : The main advantage of ketorolac over aspirin is that ketorolac (a) Can be combined more safely with an opioid such as codeine (b) Can be obtained as an over-the-counter agent (c) Does not ... (e) Is less likely to cause acute renal failure in patients with some preexisting degree of renal impairment

Last Answer : Ans: D

Description : Creatine phosphokinase isoenzyme is a marker for (A) Kidney disease (B) Liver disease (C) Myocardial infarction (D) None of these

Last Answer : Answer : C

Description : Serum AST activity is not characteristically elevated as the result of (A) Myocardial infarction (B) Passive congestion of liver (C) Muscular dystrophies (D) Peptic ulcer

Last Answer : Answer : D

Description : LDH1 and LDH2 are elevated in (A) Myocardial infarction (B) Liver disease (C) Kidney disease (D) Brain disease

Last Answer : Answer : A