For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD

For reduction enzyme HMG-CoA reductase requires cofactor: (A) NADPH (B) NADP (C) NAD (D) FAD
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Retinol and retinal are interconverted requiring dehydrogenase or reductase in the presence of (A) NAD or NADP (B) NADH + H+ (C) NADPH (D) FAD

Description : Retinol and retinal are interconverted requiring dehydrogenase or reductase in the presence of (A) NAD or NADP (B) NADH + H+ (C) NADPH (D) FAD

Last Answer : Answer : A

Synthesis of sphingosine requires the cofactor (A) NAD (B) NADP (C) NADPH+ (D) ATP

Description : Synthesis of sphingosine requires the cofactor (A) NAD (B) NADP (C) NADPH+ (D) ATP

Last Answer : Answer : C

A cofactor in the conversion of dihydroorotate to orotic acid, catalysed by the enzyme dihydroorotate dehydrogenase is (A) FAD (B) FMN (C) NAD (D) NADP

Description : A cofactor in the conversion of dihydroorotate to orotic acid, catalysed by the enzyme dihydroorotate dehydrogenase is (A) FAD (B) FMN (C) NAD (D) NADP

Last Answer : Answer : C

Mitochondrial α-ketoglutarate dehydrogenase complex requires all the following to function except (A) CoA (B) FAD (C) NAD+ (D) NADP+

Description : Mitochondrial α-ketoglutarate dehydrogenase complex requires all the following to function except (A) CoA (B) FAD (C) NAD+ (D) NADP+

Last Answer : Answer : D

β-Oxidation of fatty acids requires all the following coenzymes except (A) CoA (B) FAD (C) NAD (D) NADP

Description : β-Oxidation of fatty acids requires all the following coenzymes except (A) CoA (B) FAD (C) NAD (D) NADP

Last Answer : Answer : D

Group transferring Co-enzyme is (A) CoA (B) NAD+ (C) NADP+ (D) FAD+

Description : Group transferring Co-enzyme is (A) CoA (B) NAD+ (C) NADP+ (D) FAD+

Last Answer : Answer : A

Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+

Description : Fatty acids are activated to acyl CoA by the enzyme thiokinase: (A) NAD+ (B) NADP+ (C) CoA (D) FAD+

Last Answer : Answer : C

Retinal is reduced to retinol by retinene reductase in presence of the coenzyme (A) NAD+ (B) NADP+ (C) NADH + H+ (D) NADPH + H+

Description : Retinal is reduced to retinol by retinene reductase in presence of the coenzyme (A) NAD+ (B) NADP+ (C) NADH + H+ (D) NADPH + H+

Last Answer : Answer : C

Isocitrate dehydrogenase can use __________ as a cofactor. (A) NAD+ only (B) NADP+ only (C) NAD+ or NADP+ (D) FMN and FAD

Description : Isocitrate dehydrogenase can use __________ as a cofactor. (A) NAD+ only (B) NADP+ only (C) NAD+ or NADP+ (D) FMN and FAD

Last Answer : Answer : C

Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilising (A) NADPH + H+ (B) FAD (C) NAD (D) NADH + H+

Description : Retinal is reduced to retinol in intestinal mucosa by a specific retinaldehyde reductase utilising (A) NADPH + H+ (B) FAD (C) NAD (D) NADH + H+

Last Answer : Answer : A

A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP

Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP

Last Answer : Answer : A

The cofactor or its derivative required for the conversion of acetyl CoA to malonylCoA is (A) FAD (B) ACP (C) NAD+ (D) Biotin

Description : The cofactor or its derivative required for the conversion of acetyl CoA to malonylCoA is (A) FAD (B) ACP (C) NAD+ (D) Biotin

Last Answer : Answer : D

Pantothenic acid acts on (A) NADP (B) NADPH (C) FAD (D) CoA

Description : Pantothenic acid acts on (A) NADP (B) NADPH (C) FAD (D) CoA

Last Answer : Answer : B

The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is (A) FAD (B) FMN (C) NAD (D) NADP

Description : The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is (A) FAD (B) FMN (C) NAD (D) NADP

Last Answer : Answer : C

In β-oxidation, the coenzyme for acyl-CoA dehydrogenase is (A) FMN (B) NAD (C) NADP (D) FAD

Description : In β-oxidation, the coenzyme for acyl-CoA dehydrogenase is (A) FMN (B) NAD (C) NADP (D) FAD

Last Answer : Answer : D

An examp le of group transferr ing coenzyme is (A) NAD+ (B) NADP+ (C) FAD (D) CoA

Description : An examp le of group transferr ing coenzyme is (A) NAD+ (B) NADP+ (C) FAD (D) CoA

Last Answer : Answer : D

Carboxylation of acetyl—CoA to malonyl — CoA takes place in presence of (A) FAD+ (B) Biotin (C) NAD+ (D) NADP+

Description : Carboxylation of acetyl—CoA to malonyl — CoA takes place in presence of (A) FAD+ (B) Biotin (C) NAD+ (D) NADP+

Last Answer : Answer : C

Acyl-CoA dehydrogenase converts Acyl CoA to α-β unsaturated acyl-CoA in presence of the coenzyme: (A) NAD+ (B) NADP+ (C) ATP (D) FAD

Description : Acyl-CoA dehydrogenase converts Acyl CoA to α-β unsaturated acyl-CoA in presence of the coenzyme: (A) NAD+ (B) NADP+ (C) ATP (D) FAD

Last Answer : Answer : D

HMG-CoA is converted to mevalonate by reduction catalysed by (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Mevalonate kinase (D) Thiolase

Description : HMG-CoA is converted to mevalonate by reduction catalysed by (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Mevalonate kinase (D) Thiolase

Last Answer : Answer : B

Conversion of all-trans-retinal into alltrans-retinol requires (A) NAD (B) NADH (C) NADP (D) NADPH

Description : Conversion of all-trans-retinal into alltrans-retinol requires (A) NAD (B) NADH (C) NADP (D) NADPH

Last Answer : Answer : D

In the biosynthesis of cholesterol, the rate limiting enzyme is (A) Mevalonate kinase (B) HMG-CoA synthetase (C) HMG-CoA reductase (D) Cis-prenyl transferase

Description : In the biosynthesis of cholesterol, the rate limiting enzyme is (A) Mevalonate kinase (B) HMG-CoA synthetase (C) HMG-CoA reductase (D) Cis-prenyl transferase

Last Answer : Answer : C

An enzyme required for the synthesis of ketone bodies as well as cholesterol is (A) Acetyl CoA carboxylase (B) HMG CoA synthetase (C) HMG CoA reductase (D) HMG CoA lyase

Description : An enzyme required for the synthesis of ketone bodies as well as cholesterol is (A) Acetyl CoA carboxylase (B) HMG CoA synthetase (C) HMG CoA reductase (D) HMG CoA lyase

Last Answer : Answer : B

DNA ligase of E. coli requires which of the following co-factors? (A) FAD (B) NAD+ (C) NADP+ (D) NADH

Description : DNA ligase of E. coli requires which of the following co-factors? (A) FAD (B) NAD+ (C) NADP+ (D) NADH

Last Answer : Answer : B

Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only

Description : Decarboxylation of α-keto acids requires (A) Thiamine pyrophosphate, FAD, NAD+ (B) Flavin mononucleotide (C) NADP+ (D) NAD+ only

Last Answer : Answer : A

UDP glucose is converted to UDP glucurronate, a reaction catalysed by UDP glucose dehydrogenase requires (A) NAD+ (B) FAD (C) NADP (D) FMN

Description : UDP glucose is converted to UDP glucurronate, a reaction catalysed by UDP glucose dehydrogenase requires (A) NAD+ (B) FAD (C) NADP (D) FMN

Last Answer : Answer : A

Reduction of ribonucleotide diphosphates (NDPs) to their corresponding deoxy ribonucleotide diphosphates (dNDPs) involves (A) FMN (B) FAD (C) NAD (D) NADPH

Description : Reduction of ribonucleotide diphosphates (NDPs) to their corresponding deoxy ribonucleotide diphosphates (dNDPs) involves (A) FMN (B) FAD (C) NAD (D) NADPH

Last Answer : Answer : D

A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is (A) Fluvastatin (B) Cerivastatin (C) Lovastatin (D) Somatostatin

Description : A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is (A) Fluvastatin (B) Cerivastatin (C) Lovastatin (D) Somatostatin

Last Answer : (C) Lovastatin

In the biosynthesis of heme, condensation between succinyl CoA and glycine requires (A) NAD+ (B) FAD (C) NADH + H+ (D) B6-phosphate

Description : In the biosynthesis of heme, condensation between succinyl CoA and glycine requires (A) NAD+ (B) FAD (C) NADH + H+ (D) B6-phosphate

Last Answer : Answer : D

Thyroproxidase requires hydrogen peroxide as oxidizing agent. The H2O2 is produced by (A) FADH2 dependent enzyme (B) NADH dependent enzyme (C) NADP dependent enzyme (D) NADPH dependent enzyme

Description : Thyroproxidase requires hydrogen peroxide as oxidizing agent. The H2O2 is produced by (A) FADH2 dependent enzyme (B) NADH dependent enzyme (C) NADP dependent enzyme (D) NADPH dependent enzyme

Last Answer : Answer : D

HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids

Description : HMG-CoA reductase activity is increased by administration of the hormone: (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids

Last Answer : Answer : A

The activity of HMG-CoA reductase is inhibited by (A) A fungal inhibitor mevastatin (B) Probucol (C) Nicotinic acid (D) Clofibrate

Description : The activity of HMG-CoA reductase is inhibited by (A) A fungal inhibitor mevastatin (B) Probucol (C) Nicotinic acid (D) Clofibrate

Last Answer : Answer : A

Cholesterol by a feed back mechanism inhibits the activity of (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Thilase (D) Mevalonate kinase

Description : Cholesterol by a feed back mechanism inhibits the activity of (A) HMG-CoA synthetase (B) HMG-CoA reductase (C) Thilase (D) Mevalonate kinase

Last Answer : Answer : B

The rage limiting step cholesterol biosynthesis is (A) Squalene synthetase (B) Mevalonate kinase (C) HMG CoA synthetase (D) HMG CoA reductase

Description : The rage limiting step cholesterol biosynthesis is (A) Squalene synthetase (B) Mevalonate kinase (C) HMG CoA synthetase (D) HMG CoA reductase

Last Answer : Answer : D

Lovastatin is a (A) Competitive inhibitor of acetyl CoA carboxylase (B) Competitive inhibitor of HMG CoA synthetase (C) Non-competitive inhibitor of HMG CoA reductase (D) Competitive inhibitor of HMG CoA reductase

Description : Lovastatin is a (A) Competitive inhibitor of acetyl CoA carboxylase (B) Competitive inhibitor of HMG CoA synthetase (C) Non-competitive inhibitor of HMG CoA reductase (D) Competitive inhibitor of HMG CoA reductase

Last Answer : Answer : D

How do NADP+ and NADPH differ from NAD+ and NADH?

Description : How do NADP+ and NADPH differ from NAD+ and NADH?

Last Answer : These pairs of molecules are identical except for the presence of a phosphate group at the 2′ position on the ribose moiety. This is not a high-energy phosphate but rather a molecular tag that ... of fuels, while simultaneously the NADPH to NADP+ ratio can be very high, facilitating biosynthesis.  

NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae

Description : NAD is required as a coenzyme for (A) Malate dehydrogenase (B) Succinate dehydrogenase (C) Glucose-6-phosphate dehydrogenase (D) HMG CoA reductae

Last Answer : Answer : A

For synthesis of sphingosine, all the following coenzymes are required except (A) Pyridoxal phosphate (B) NADPH (C) FAD (D) NAD

Description : For synthesis of sphingosine, all the following coenzymes are required except (A) Pyridoxal phosphate (B) NADPH (C) FAD (D) NAD

Last Answer : Answer : D

The prosthetic group of aerobic dehydrogenases is (A) NAD (B) NADP (C) FAD (D) Pantothenic acid

Description : The prosthetic group of aerobic dehydrogenases is (A) NAD (B) NADP (C) FAD (D) Pantothenic acid

Last Answer : Answer : C

All the isoenzymes function with the coenzyme: (A) NADP+ (B) FAD (C) Lipoate (D) NAD+

Description : All the isoenzymes function with the coenzyme: (A) NADP+ (B) FAD (C) Lipoate (D) NAD+

Last Answer : Answer : D

Dehydrogenases utilize, as coenzymes, all of the following except (A) NAD+ (B) NADP+ (C) FAD (D) FH4

Description : Dehydrogenases utilize, as coenzymes, all of the following except (A) NAD+ (B) NADP+ (C) FAD (D) FH4

Last Answer : Answer : D

The hydrogen acceptor used in pentose phosphate pathway is (A) NAD (B) NADP (C) FAD (D) FMN

Description : The hydrogen acceptor used in pentose phosphate pathway is (A) NAD (B) NADP (C) FAD (D) FMN

Last Answer : Answer : B

In β−oxidation of fatty acids which of the following are utilized as co-enzymes? (A) NAD+ and NADP+ (B) FAD H2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+

Description : In β−oxidation of fatty acids which of the following are utilized as co-enzymes? (A) NAD+ and NADP+ (B) FAD H2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+

Last Answer : Answer : D

In β-Oxidation of fatty acids, which of the following are utilized as coenzymes? (A) NAD+ and NADP+ (B) FADH2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+

Description : In β-Oxidation of fatty acids, which of the following are utilized as coenzymes? (A) NAD+ and NADP+ (B) FADH2 and NADH + H+ (C) FAD and FMN (D) FAD and NAD+

Last Answer : Answer : D

Dehydrogenases involved in HMP shunt are specific for (A) NADP+ (B) NAD+ (C) FAD (D) FMN

Description : Dehydrogenases involved in HMP shunt are specific for (A) NADP+ (B) NAD+ (C) FAD (D) FMN

Last Answer : A

Dehydrogenase enzymes of the hexose monophosphate shunt are (A) NAD+ specific (B) NADP+ specific (C) FAD specific (D) FMN specific

Description : Dehydrogenase enzymes of the hexose monophosphate shunt are (A) NAD+ specific (B) NADP+ specific (C) FAD specific (D) FMN specific

Last Answer : B

UDPG is oxidized to UDP glucuronic acid by UDP dehydrogenase in presence of (A) FAD+ (B) NAD+ (C) NADP+ (D) ADP+

Description : UDPG is oxidized to UDP glucuronic acid by UDP dehydrogenase in presence of (A) FAD+ (B) NAD+ (C) NADP+ (D) ADP+

Last Answer : B

Select the first line hypolipidemic drug/drugs for treating hypertriglyceridemia in a subject with normal cholesterol level: A. Fibrates B. HMG-CoA reductase inhibitors C. Nicotinic acid D. Both 'A' and 'C' are correc

Description : Select the first line hypolipidemic drug/drugs for treating hypertriglyceridemia in a subject with normal cholesterol level: A. Fibrates B. HMG-CoA reductase inhibitors C. Nicotinic acid D. Both 'A' and 'C' are correc

Last Answer : D. Both 'A' and 'C' are correct

Select the most appropriate hypolipidemic drug for a patient with raised LDL-cholesterol level but normal triglyceride level: A. A HMG-CoA reductase inhibitor B. A fibric acid derivative C. Gugulipid D. Nicotinic acid

Description : Select the most appropriate hypolipidemic drug for a patient with raised LDL-cholesterol level but normal triglyceride level: A. A HMG-CoA reductase inhibitor B. A fibric acid derivative C. Gugulipid D. Nicotinic acid

Last Answer : A. A HMG-CoA reductase inhibitor

Choose the most potent and most efficacious LDLcholesterol lowering HMG-CoA reductase inhibitor: A. Lovastatin B. Simvastatin C. Pravastatin D. Atorvastatin

Description : Choose the most potent and most efficacious LDLcholesterol lowering HMG-CoA reductase inhibitor: A. Lovastatin B. Simvastatin C. Pravastatin D. Atorvastatin

Last Answer : D. Atorvastatin

A pathway that requires NADPH as a cofactor is (A) Extramitochondrial folic acid synthesis (B) Ketone body formation (C) Glycogenesis (D) Gluconeogenesis

Description : A pathway that requires NADPH as a cofactor is (A) Extramitochondrial folic acid synthesis (B) Ketone body formation (C) Glycogenesis (D) Gluconeogenesis

Last Answer : Answer : A