Hypercholesterolemia is found in (A) Xanthomatosis (B) Thyrotoxicosis (C) Hemolytic jaundice (D) Malabsorption syndrom

Hypercholesterolemia is found in (A) Xanthomatosis (B) Thyrotoxicosis (C) Hemolytic jaundice (D) Malabsorption syndrom
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Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Description : Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome

Last Answer : Answer : A

A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of (a) Agranulocytosis (b) Gallstones (c) Lactic acidosis (d) Myopathy (e) Thyrotoxicosis

Description : A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of (a) Agranulocytosis (b) Gallstones (c) Lactic acidosis (d) Myopathy (e) Thyrotoxicosis

Last Answer : Ans: D

Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome

Description : Hypocholesterolemia is found in (A) Thyrotoxicosis (B) Diabetes mellitus (C) Obstructive jaundice (D) Nephrotic syndrome

Last Answer : Answer : A

A mixture of conjugated and unconjugated bilirubin is found in the circulation in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Post hepatic jaundice

Description : A mixture of conjugated and unconjugated bilirubin is found in the circulation in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Post hepatic jaundice

Last Answer : Answer : B

In hemolytic jaundice, bilirubin in urine is (A) Usually absent (B) Usually present (C) Increased very much (D) Very low

Description : In hemolytic jaundice, bilirubin in urine is (A) Usually absent (B) Usually present (C) Increased very much (D) Very low

Last Answer : Answer : A

In hemolytic jaundice, the urinary bilirubin is (A) Normal (B) Absent (C) More than normal (D) Small amount is present

Description : In hemolytic jaundice, the urinary bilirubin is (A) Normal (B) Absent (C) More than normal (D) Small amount is present

Last Answer : Answer : C

Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis

Last Answer : Answer : D

The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma

Description : The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma

Last Answer : Answer : A

Immediate direct Vanden Bergh reaction indicates (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Megalobastic anemia

Description : Immediate direct Vanden Bergh reaction indicates (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Megalobastic anemia

Last Answer : Answer : B

A complete absence of fecal urobilinogen is strongly suggestive of (A) Obstruction of bile duct (B) Hemolytic jaundice (C) Intrahepatic cholestasis (D) Malignant obstructive disease

Description : A complete absence of fecal urobilinogen is strongly suggestive of (A) Obstruction of bile duct (B) Hemolytic jaundice (C) Intrahepatic cholestasis (D) Malignant obstructive disease

Last Answer : Answer : D

Fecal urobilinogen is decreased in (A) Obstruction of biliary duct (B) Hemolytic jaundice (C) Excess fat intake (D) Low fat intake

Description : Fecal urobilinogen is decreased in (A) Obstruction of biliary duct (B) Hemolytic jaundice (C) Excess fat intake (D) Low fat intake

Last Answer : Answer : A

Fecal urobilinogen is increased in (A) Hemolytic jaundice (B) Obstruction of biliary duct (C) Extrahepatic gall stones (D) Enlarged lymphnodes

Description : Fecal urobilinogen is increased in (A) Hemolytic jaundice (B) Obstruction of biliary duct (C) Extrahepatic gall stones (D) Enlarged lymphnodes

Last Answer : Answer : A

Fecal stercobilinogen is increased in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Viral hepatitis (D) Obstructive jaundice

Description : Fecal stercobilinogen is increased in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Viral hepatitis (D) Obstructive jaundice

Last Answer : Answer : B

A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice

Last Answer : Answer : B

Increased urobilinogen in urine and absence of bilirubin in the urine suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Viral hepatitis (D) Toxic jaundice

Description : Increased urobilinogen in urine and absence of bilirubin in the urine suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Viral hepatitis (D) Toxic jaundice

Last Answer : Answer : A

One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency

Last Answer : Answer : A

An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis

Description : An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis

Last Answer : Answer : A

Which type of jaundice in adults is the result of increased destruction of red blood cells? a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot excrete the bilirubin as quickly as it is formed.

Description : Which type of jaundice in adults is the result of increased destruction of red blood cells? a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot ... is the result of liver disease. d) Non-obstructive Non-obstructive jaundice occurs with hepatitis.

Last Answer : a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot excrete the bilirubin as quickly as it is formed.

The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Last Answer : Answer : D

What are the drugs available to treat hypercholesterolemia?

Description : What are the drugs available to treat hypercholesterolemia?

Last Answer : Bile acid binding recins, HMGCoA reductase inhibitors, fibrate derivatives, nicotinic acid.

Hypercholesterolemia is seen in what conditions?

Description : Hypercholesterolemia is seen in what conditions?

Last Answer : Diabetes mellitus, nephrotic syndrome, obstructive jaundice, hypothyroidism.

Serum inorganic phosphorous decreases in all the following conditions except (A) Hyperparathyroidism (B) Intestinal malabsorption (C) Osteomalacia (D) Chronic renal failure

Description : Serum inorganic phosphorous decreases in all the following conditions except (A) Hyperparathyroidism (B) Intestinal malabsorption (C) Osteomalacia (D) Chronic renal failure

Last Answer : Answer : D

Hypocalcaemia can occur in all the following except (A) Rickets (B) Osteomalacia (C) Hyperparathyroidism (D) Intestinal malabsorption

Description : Hypocalcaemia can occur in all the following except (A) Rickets (B) Osteomalacia (C) Hyperparathyroidism (D) Intestinal malabsorption

Last Answer : Answer : C

Deficiency of vitamin B12 can occur because of (A) Decreased intake of vitamin B12 (B) Atrophy of gastric mucosa (C) Intestinal malabsorption (D) All of these

Description : Deficiency of vitamin B12 can occur because of (A) Decreased intake of vitamin B12 (B) Atrophy of gastric mucosa (C) Intestinal malabsorption (D) All of these

Last Answer : Answer : D

Positive nitrogen balance is seen in (A) Starvation (B) Wasting diseases (C) Growing age (D) Intestinal malabsorption

Description : Positive nitrogen balance is seen in (A) Starvation (B) Wasting diseases (C) Growing age (D) Intestinal malabsorption

Last Answer : Answer : C

A decrease in serum sodium may occur in (A) Adrenocortical insufficiency (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Thyrotoxicosis

Description : A decrease in serum sodium may occur in (A) Adrenocortical insufficiency (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Thyrotoxicosis

Last Answer : Answer : A

BMR is increased in (A) Endemic goitre (B) Thyrotoxicosis (C) Myxoedema (D) Cretinism

Description : BMR is increased in (A) Endemic goitre (B) Thyrotoxicosis (C) Myxoedema (D) Cretinism

Last Answer : Answer : B

Mental retardation can occur in (A) Cretinism (B) Juvenile myxoedema (C) Myxoedema (D) Juvenile thyrotoxicosis

Description : Mental retardation can occur in (A) Cretinism (B) Juvenile myxoedema (C) Myxoedema (D) Juvenile thyrotoxicosis

Last Answer : Answer : A

Excessive secretion of ACTH causes (A) Cushing’s syndrome (B) Addison’s disease (C) Myxoedema (D) Thyrotoxicosis

Description : Excessive secretion of ACTH causes (A) Cushing’s syndrome (B) Addison’s disease (C) Myxoedema (D) Thyrotoxicosis

Last Answer : Answer : A

Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking

Description : Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking

Last Answer : C

Glucose tolerance is increased in (A) Diabetes mellitus (B) Adrenalectomy (C) Acromegaly (D) Thyrotoxicosis

Description : Glucose tolerance is increased in (A) Diabetes mellitus (B) Adrenalectomy (C) Acromegaly (D) Thyrotoxicosis

Last Answer : B

Serum cholesterol is decreased in (A) Endemic goitre (B) Thyrotoxicosis (C) Myxoedema (D) Cretinism

Description : Serum cholesterol is decreased in (A) Endemic goitre (B) Thyrotoxicosis (C) Myxoedema (D) Cretinism

Last Answer : B

Low uptake of 123I on the thyroid uptake scan would be an expected finding in: 1) A solitary toxic nodule 2) A multi-nodular toxic goitre 3) Amiodarone induced thyrotoxicosis type 1 4) DeQuervain's thyroiditis 5) Graves' thyrotoxicosis

Description : Low uptake of 123I on the thyroid uptake scan would be an expected finding in: 1) A solitary toxic nodule 2) A multi-nodular toxic goitre 3) Amiodarone induced thyrotoxicosis type 1 4) DeQuervain's thyroiditis 5) Graves' thyrotoxicosis

Last Answer : Answers-4 DeQuervain's thyroiditis is classically associated with low or absent 123I (the 131 radioactive isotope of iodine) uptake. The others will have high or normal uptake. In particular type ... may be distinguished from the thyroiditis of type 2 by the normal or high uptake scan.

Familial hypercholesterolemia?

Description : Familial hypercholesterolemia?

Last Answer : DefinitionFamilial hypercholesterolemia is a disorder of high LDL ("bad") cholesterol that is passed down through families, which means it is inherited. The condition begins at birth and can cause heart attacks ... LDL in the blood. High levels of LDL cholesterol make you more likely to have narro

Angiotensin II plays a key role in the following risk factor for ischaemic heart disease: A. Hypercholesterolemia B. Ventricular hypertrophy C. Carbohydrate intolerance D. Cardiac arrhythmia

Description : Angiotensin II plays a key role in the following risk factor for ischaemic heart disease: A. Hypercholesterolemia B. Ventricular hypertrophy C. Carbohydrate intolerance D. Cardiac arrhythmia

Last Answer : B. Ventricular hypertrophy

Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Description : Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders? (A) Serum AST (B) Serum ALT (C) Serum LDH (D) Serum γ-GT

Last Answer : Answer : D

Malabsorption?

Description : Malabsorption?

Last Answer : DefinitionMalabsorption is difficulty digesting or absorbing nutrients from food.Causes, incidence, and risk factorsMany diseases can cause malabsorption. Malabsorption is usually the inability ... obesity, partial or complete removal of the ileum)CholestasisChronic liver diseaseChronic pancreatiti

Celiac sprue is an example of which category of malabsorption? a) Mucosal disorders causing generalized malabsorption In addition to celiac sprue, regional enteritis and radiation enteritis are examples of mucosal disorders.

Description : Celiac sprue is an example of which category of malabsorption? a) Mucosal disorders causing generalized malabsorption In addition to celiac sprue, regional enteritis and radiation ... malabsorption Postoperative gastric or intestinal resection can result in development of malabsorption syndromes.

Last Answer : a) Mucosal disorders causing generalized malabsorption In addition to celiac sprue, regional enteritis and radiation enteritis are examples of mucosal disorders.

The presence of mucus and pus in the stools suggests a) Inflammatory colitis The presence of mucus and pus in the stools suggests inflammatory colitis or enteritis. b) Small bowel disease Watery stools are characteristic of small bowel disease. c) Disorders of the colon Loose, semisolid stools are associated more often with disorders of the colon. d) Intestinal malabsorption Voluminous, greasy stools suggest intestinal malabsorption.

Description : The presence of mucus and pus in the stools suggests a) Inflammatory colitis The presence of mucus and pus in the stools suggests inflammatory colitis or enteritis. b) Small bowel ... with disorders of the colon. d) Intestinal malabsorption Voluminous, greasy stools suggest intestinal malabsorption.

Last Answer : a) Inflammatory colitis The presence of mucus and pus in the stools suggests inflammatory colitis or enteritis.

Crohn’s disease is a condition of malabsorption caused by a) inflammation of all layers of intestinal mucosa. Crohn’s disease is also known as regional enteritis and can occur anywhere along the GI tract, but most commonly at the distal ileum and in the colon.

Description : Crohn's disease is a condition of malabsorption caused by a) inflammation of all layers of intestinal mucosa. Crohn's disease is also known as regional enteritis and can occur ... to lactose intolerance. d) gastric resection. Postoperative malabsorption occurs after gastric or intestinal resection.

Last Answer : a) inflammation of all layers of intestinal mucosa. Crohn’s disease is also known as regional enteritis and can occur anywhere along the GI tract, but most commonly at the distal ileum and in the colon.

Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase

Description : Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme: (A) 6-Phosphogluconate dehydrogenase (B) Glucose-6-phosphate dehydrogenase (C) Epimerase (D) Transketolase

Last Answer : Answer : B

Acute hemolytic anemia in person’s sensitive to the Fava beans is due to the deficiency of the enzyme: (A) Pyruvate dehydrogenase (B) G-6-PD (C) Aconitase (D) Transketolase

Description : Acute hemolytic anemia in person’s sensitive to the Fava beans is due to the deficiency of the enzyme: (A) Pyruvate dehydrogenase (B) G-6-PD (C) Aconitase (D) Transketolase

Last Answer : Answer : B

Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase

Description : Hemolytic anemia is caused by the deficiency of certain enzymes of the pentose phosphate pathway, the principal enzyme involved is (A) Glucose-6-phosphate dehydrogenase (B) Aldolase (C) Fructose 1, 6-bisphosphatase (D) Phosphohexose isomerase

Last Answer : Answer : A

Folate deficiency causes (A) Microcytic anemia (B) Hemolytic anemia (C) Iron deficiency anemia (D) Megaloblastic anemia

Description : Folate deficiency causes (A) Microcytic anemia (B) Hemolytic anemia (C) Iron deficiency anemia (D) Megaloblastic anemia

Last Answer : Answer : D

An important finding of Fabry’s disease is (A) Skin rash (B) Exophthalmos (C) Hemolytic anemia (D) Mental retardation

Description : An important finding of Fabry’s disease is (A) Skin rash (B) Exophthalmos (C) Hemolytic anemia (D) Mental retardation

Last Answer : Answer : A

The pH of gastric juice become low in (A) Hemolytic anemia (B) Pernicious anemia (C) Both (A) and (B) (D) None of these

Description : The pH of gastric juice become low in (A) Hemolytic anemia (B) Pernicious anemia (C) Both (A) and (B) (D) None of these

Last Answer : Answer : B

Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate

Last Answer : B

Acute hemolytic episode after administration of antimalarial drug is due to what?

Description : Acute hemolytic episode after administration of antimalarial drug is due to what?

Last Answer : Deficiency of glucose-6-phosphate dehydrogenase.

Digoxin given for cardiac failure is extremely valuable in patients of (a) Thyrotoxicosis (b) Beriberi (c) Cor pulmonale (d) Atrial fibrillation

Description : Digoxin given for cardiac failure is extremely valuable in patients of (a) Thyrotoxicosis (b) Beriberi (c) Cor pulmonale (d) Atrial fibrillation

Last Answer : Ans: D

Toxic agents present in food which interfere with thyroxine synthesis lead to the development of (a) toxic goitre (b) cretinism (c) simple goitre (d) thyrotoxicosis

Description : Toxic agents present in food which interfere with thyroxine synthesis lead to the development of (a) toxic goitre (b) cretinism (c) simple goitre (d) thyrotoxicosis

Last Answer : (c) simple goitre