Familial hypercholesterolemia?

Familial hypercholesterolemia?
by

1 Answer

Answer :

DefinitionFamilial hypercholesterolemia is a disorder of high LDL ("bad") cholesterol that is passed down through families, which means it is inherited. The condition begins at birth and can cause heart attacks at an early age.See also:Familial combined hyperlipidemiaFamilial hypertriglyceridemiaFamilial dysbetalipoproteinemiaAlternative NamesType II hyperlipoproteinemia; Hypercholesterolemic xanthomatosis; Low density lipoprotein receptor mutationCauses, incidence, and risk factorsFamilial hypercholesterolemia is a genetic disorder caused by a defect on chromosome 19.The defect makes the body unable to remove low density lipoprotein (LDL, or "bad") cholesterol from the blood. This results in high levels of LDL in the blood. High levels of LDL cholesterol make you more likely to have narro
by
selected by

Related questions

The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Description : The primary biochemical lesion in homozygote with familial hypercholesterolemia (type IIa) is (A) Loss of feed back inhibition of HMG reductase (B) Loss of apolipoprotein B (C) Increased production of LDL from VLDL (D) Functional deficiency of plasma membrane receptors for LDL

Last Answer : Answer : D

Hypercholesterolemia is found in (A) Xanthomatosis (B) Thyrotoxicosis (C) Hemolytic jaundice (D) Malabsorption syndrom

Description : Hypercholesterolemia is found in (A) Xanthomatosis (B) Thyrotoxicosis (C) Hemolytic jaundice (D) Malabsorption syndrom

Last Answer : Answer : A

A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of (a) Agranulocytosis (b) Gallstones (c) Lactic acidosis (d) Myopathy (e) Thyrotoxicosis

Description : A 54-year-old woman with severe hypercholesterolemia is to be treated with a combination of niacin and atorvastatin. With this drug combination, it is important that the patient be monitored closely for signs of (a) Agranulocytosis (b) Gallstones (c) Lactic acidosis (d) Myopathy (e) Thyrotoxicosis

Last Answer : Ans: D

What are the drugs available to treat hypercholesterolemia?

Description : What are the drugs available to treat hypercholesterolemia?

Last Answer : Bile acid binding recins, HMGCoA reductase inhibitors, fibrate derivatives, nicotinic acid.

Hypercholesterolemia is seen in what conditions?

Description : Hypercholesterolemia is seen in what conditions?

Last Answer : Diabetes mellitus, nephrotic syndrome, obstructive jaundice, hypothyroidism.

Angiotensin II plays a key role in the following risk factor for ischaemic heart disease: A. Hypercholesterolemia B. Ventricular hypertrophy C. Carbohydrate intolerance D. Cardiac arrhythmia

Description : Angiotensin II plays a key role in the following risk factor for ischaemic heart disease: A. Hypercholesterolemia B. Ventricular hypertrophy C. Carbohydrate intolerance D. Cardiac arrhythmia

Last Answer : B. Ventricular hypertrophy

Did death sever familial ties for the Chinese?

Description : Did death sever familial ties for the Chinese?

Last Answer : What is the answer ?

Transient familial hyperbilirubinemia?

Description : Transient familial hyperbilirubinemia?

Last Answer : DefinitionTransient familial hyperbilirubinemia is a metabolic disorder that is passed down through families. Babies with this disorder are born with severe jaundice.Alternative NamesLucey-Driscol ... can identify the severity of the jaundice.TreatmentPhototherapywith blue light is used to

Familial dysbetalipoproteinemia?

Description : Familial dysbetalipoproteinemia?

Last Answer : DefinitionFamilial dysbetalipoproteinemia is a disorder passed down through families in which there are high amounts of cholesterol and triglycerides in the blood.Alternative NamesType III hyperlipoproteinemia; Deficient or ... may not be seen until age 20 or older.Yellow deposits of fatty ma

Familial hypertriglyceridemia?

Description : Familial hypertriglyceridemia?

Last Answer : DefinitionFamilial hypertriglyceridemia is a common disorder passed down through families in which the level of triglycerides (a type of fat) in a person's blood are higher than ... Familial hypertriglyceridemia does not usually become noticeable until puberty or early adulthood. Obesity, hyper

Serum potassium level decreases in (A) Familial periodic paralysis (B) Addison’s disease (C) Renal failure (D) All of these

Description : Serum potassium level decreases in (A) Familial periodic paralysis (B) Addison’s disease (C) Renal failure (D) All of these

Last Answer : Answer : A

Familial hypertriaacylglycerolemia is associated with (A) Over production of VLDL (B) Increased LDL concentration (C) Increased HDL concentration (D) Slow clearance of chylomicrons

Description : Familial hypertriaacylglycerolemia is associated with (A) Over production of VLDL (B) Increased LDL concentration (C) Increased HDL concentration (D) Slow clearance of chylomicrons

Last Answer : Answer : A

Propranolol is useful in all of the following except (a) Angina (b) Familial tremor (c) Hypertension (d) Idiopathic hypertrophic subaortic cardiomyopathy (e) Partial atrioverntricular heart block

Description : Propranolol is useful in all of the following except (a) Angina (b) Familial tremor (c) Hypertension (d) Idiopathic hypertrophic subaortic cardiomyopathy (e) Partial atrioverntricular heart block

Last Answer : Ans: E

Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Description : Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Last Answer : Answers-1 Familial hypercholesterolaemia is an autosomal dominant condition manifest by increased LDL concentrations (not chylomicrons) due to constitutional abnormalities and reduced numbers of ... are characteristic and the condition is associated with a premature cardiovascular mortality.

Which of the following suggests a diagnosis of familial combined hyperlipidaemia (FCHL) rather than heterozygous familial hypercholesterolaemia (FH)? 1) Tendon xanthomas 2) Presence of glucose intolerance 3) Strong family history of premature coronary artery disease 4) Presence of arcus senilus 5) Absence of hyperuricaemia

Description : Which of the following suggests a diagnosis of familial combined hyperlipidaemia (FCHL) rather than heterozygous familial hypercholesterolaemia (FH)? 1) Tendon xanthomas 2) Presence of glucose ... premature coronary artery disease 4) Presence of arcus senilus 5) Absence of hyperuricaemia

Last Answer : Answers-2 The genetic dislipidaemias occur in one third of patients who have suffered from their first myocardial infarction below the age of 50 years in men. The commonest is familial combined ... xanthomata and arcus cornea are rarely present in children, but are very important signs to identify.

Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia

Description : Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia

Last Answer : Answers-5 Lipoprotein lipase deficiency is autosomal recessive and associated with increased chylomicrons and marked hypertriglyceridaemia.

Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Description : Which of the following is a characteristic feature of familial hypercholesterolaemia? 1) Autosomal dominant inheritance 2) elevated chylomicrons 3) hypertriglyceridaemia 4) increased expression of LDL receptors 5) Palmar xanthomas

Last Answer : Answers-1 Familial hypercholesterolaemia is an autosomal dominant condition manifest by increased LDL concentrations (not chylomicrons) due to constitutional abnormalities and reduced numbers of ... are characteristic and the condition is associated with a premature cardiovascular mortality.

Which of the following characteristics are risk factors for colorectal cancer? a) Familial polyposis Family history of colon cancer or familial polyposis is a risk factor for colorectal cancer.

Description : Which of the following characteristics are risk factors for colorectal cancer? a) Familial polyposis Family history of colon cancer or familial polyposis is a risk factor for colorectal cancer. b) Age ... of skin cancer History of skin cancer is not a recognized risk factor for colorectal cancer.

Last Answer : a) Familial polyposis Family history of colon cancer or familial polyposis is a risk factor for colorectal cancer.

Which hypolipidemic drug has been used to control and prevent pancreatitis in familial hypertriglyceridemia: A. Lovastatin B. Nicotinic acid C. Cholestyramine D. Clofibrate

Description : Which hypolipidemic drug has been used to control and prevent pancreatitis in familial hypertriglyceridemia: A. Lovastatin B. Nicotinic acid C. Cholestyramine D. Clofibrate

Last Answer : B. Nicotinic acid

It is popularly said that any two students are not alike. The meaning of this phrase is Options: A) The students differ in their physical make-up B) The students differ in their mental make-up C) The students differ in their familial and social status D) All the above statements are correct

Description : It is popularly said that any two students are not alike. The meaning of this phrase is Options: A) The students differ in their physical make-up B) The students differ in their mental make-up C) The students differ in their familial and social status D) All the above statements are correct

Last Answer : D) All the above statements are correct