Description : Which of the following statements about Menke’s disease are true. (A) It is an inherited disorder of copper metabolism (B) It occurs only in males (C) Plasma copper is increased in it (D) Hair becomes steely and kinky in it
Last Answer : Answer : C
Description : Ceruloplasmin is absent in (A) Cirrhosis of liver (B) Wilson’s disease (C) Menke’s disease (D) Copper deficiency
Last Answer : Answer : B
Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease
Description : In Wilson’s disease (A) Copper fails to be excreted in the bile (B) Copper level in plasma is decreased (C) Ceruloplasmin level is increased (D) Intestinal absorption of copper is decreased
Last Answer : Answer : A
Description : What is ceruloplasmin? (A) Plasma protein (B) Stored form of copper (C) Both A and B (D) None of these
Description : Menke’s disease is due to an abnormality in the metabolism of (A) Iron (B) Manganese (C) Magnesium (D) Copper
Last Answer : Answer : D
Description : Lesch-Nyhan syndrome, the sex linked, recessive absence of HGPRTase, may lead to (A) Compulsive self destructive behaviour with elevated levels of urate in serum (B) Hypouricemia due to liver damage (C) Failure to thrive and megaloblastic anemia (D) Protein intolerance and hepatic encephalopathy
Description : In hepatic diseases (A) Both the bound iron and total iron binding capacity of the plasma may be low (B) Both the bound iron and total iron binding capacity of the plasma may be high (C) Only bound iron may be high (D) Only the total iron binding capacity may be high
Description : Gout is characterized by increased plasma levels of (A) Urea (B) Uric acid (C) Creatine (D) Creatinine
Description : Zinc deficiency occurs commonly in (A) Acrodermatitis enteropathica (B) Wilson’s disease (C) Xeroderma pigmentosum (D) Menke’s disease
Description : Abnormal collagen structure is seen in all of the following except (A) I-cell disease (B) Osteogenesis imperfecta (C) Menke’s disease (D) Ehlers-Danlos sydrome
Description : Ceruloplasmin oxidizes (A) Copper (B) Iron (C) Both (A) and (B) (D) None of these
Description : Essential fructosuria is characterized by the lack of the hepatic enzyme: (A) Phosphohexose isomerase (B) Aldalose A (C) Aldolase B (D) Fructokinase
Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it
Description : All of the following are true of Wilson’s disease except (A) Low total plasma Cu (B) Elevated urinary copper (C) Arthritis (D) Aminoaciduria
Description : Transdermal drug delivery systems offer the following advantages except: A. They produce high peak plasma concentration of the drug B. They produce smooth and nonfluctuating plasma concentration of the ... the achieved plasma drug concentration D. They avoid hepatic first-pass metabolism of the drug
Last Answer : A. They produce high peak plasma concentration of the drug
Last Answer : A
Description : Choose the correct statement about topical NSAID preparations: A. They produce high drug levels in the blood by avoiding hepatic first pass metabolism B. They produce high drug levels in ... a strong placebo effect D. Interindividual variability in clinical response to these preparations is minimal
Last Answer : C. They elicit symptomatic relief in soft tissue rheumatism mainly by a strong placebo effect
Description : Why are grey/white hairs all "kinky"?
Last Answer : Here ya go.
Description : What are good kinky dares?
Last Answer : Need answer
Description : Ceruloplasmin shows the activity (A) As ferroxidase (B) As reductase (C) As ligase (D) As transferase
Description : The normal serum concentration of ceruloplasmin in mg/100 ml varies between (A) 5–10 (B) 10–20 (C) 25–43 (D) 50–100
Description : Iron is a component of (A) Hemoglobin (B) Ceruloplasmin (C) Transferase (D) Transaminase
Description : Proteins that carries Iron into different tissues is (A) Ceruloplasmin (B) Trans cortin (C) Mucoproteins (D) Glycoproteins
Description : Activity of ceruloplasmin shown in vitro: (A) Reductase (B) Hydrolase (C) Ligase (D) Oxidase
Description : A/G ratio is (A) Strength of proteins (B) ratio of serum proteins (C) ratio of ceruloplasmin (D) None of these
Description : Ceruloplasmin is (A) α1-globulin (B) α2-globulin (C) β-globulin (D) None of these
Description : An example of metalloprotein is (A) Casein (B) Ceruloplasmin (C) Gelatin (D) Salmine
Description : A number of changes in trace mineral metabolism are noted during sepsis. Which of the following change(s) may be observed in a septic or trauma patient? a. Plasma iron levels are noted to ... are noted to decrease c. Plasma serum zinc levels may decrease d. Administration of iron is appropriate
Last Answer : Answer: a, c Changes in the balance of magnesium, inorganic phosphate, zinc, and potassium generally follow alterations in nitrogen balance. Although the iron-binding capacity of transferrin ... concentrations can be ascribed almost entirely to the levels of the ceruloplasmin produced by the liver
Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT
Description : In case of wilson’s disease, the features include all of the following except (A) Progressive hepatic cirrhosis (B) Keyser Fleisher ring (C) Aminoaciduria (D) Urinary excretion of Cu is decreased
Description : The active transport system for hepatic uptake of bilirubin is congenitally defective in (A) Gilbert’s disease (B) Crigler-Najjar syndrome (C) Rotor’s syndrome (D) Dubin-Johnson syndrome
Description : . Sickle-cell anaemia is (a) caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin (b) caused by a change in a single base pair of DNA (c) characterized by elongated sickle like RBCs with a nucleus (d) an autosomal linked dominant trait.
Last Answer : (b) caused by a change in a single base pair of DNA
Description : Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose ... The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism
Last Answer : Answer: b, c A broad spectrum of metabolic abnormalities become apparent in sepsis and the systemic inflammatory response syndrome following shock. Disruption of the normal cycles of carbohydrate, ... acetyl coenzyme A. This results in reduced serum level of leucine, isoleucine and valine
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : Plasma non-functional enzymes are (A) totally absent (B) low concentration in plastic (C) important for diagnosis of several disease (D) All of these
Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase
Description : Regarding the antibacterial action of gentamicin, which one of the following statements is most accurate? (a) Efficacy is directly proportionate to the time that the plasma level of the drug is ... an inhibitor of cell wall synthesis (e) The antibacterial action of gentamicin is time - dependent
Last Answer : Ans: C
Description : Pentosuria is a rare hereditary disease is characterized by increased urinary excretion of (A) L-xylulose (B) Xylitol (C) Xylulose 5-phosphate (D) Ribose 5-phosphate
Description : Tarui disease is characterized by the deficiency of the enzyme: (A) Liver phosphorylase (B) Muscle phosphorylase (C) Muscle and erythrocyte phosphofructokinase (D) Lysosomal acid maltase
Description : Her’s disease is characterized by deficiency of (A) Muscle phosphorylase (B) Liver phosphorylase (C) Debranching enzyme (D) Glycogen synthase
Description : Von Gierke’s disease is characterized by the deficiency of (A) Glucose-6-phosphatase (B) α -1→ 4 Glucosidase (C) 1→ 6 Glucosidase (D) Liver phosphorylase
Description : Which of the following condition is characterized by ketonuria but without glycosuria? (A) Diabetes mellitus (B) Diabetes insipidus (C) Prolonged starvation (D) Addison’s disease
Description : Early granulation tissue is BEST characterized by the presence of: C A. Plasma cells and macrophages B. T lymphocytes and eosinophils C. Capillary buds and fibroblasts D. None of these
Last Answer : Capillary buds and fibroblast
Description : Ceruloplasmin?
Last Answer : DefinitionCeruloplasmin is a copper-containing protein. This article discusses the test to measure the level of the protein in the clear liquid part of the blood (serum).How the test is performedBlood is ... the needle is removed, and the puncture site is covered to stop any bleeding.In infants or
Description : Are activity levels and sleep requirements linked?
Last Answer : For me, personally, the level of physical exertion affects the quality of my sleep, not the quantity. Most nights I get around 7 hours. If I have had a high exertion day, my sleep is much deeper, I barely ... a sedentary day, my sleep is very light, I toss and turn, and I don't feel as well rested.
Description : Which of the following statement(s) is/are true concerning hemophilia A? a. Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII b. A positive family history for ... platelet aggregation d. Spontaneous bleeding is unusual with factor VIII levels greater than 10% of normal
Last Answer : Answer: a, d Hemophilia A is inherited as a sex-linked recessive deficiency of factor VIII although 0% of cases are secondary to spontaneous mutation. The incidence of this abnormality is ... factor levels as low as 1% have been noted and patients are at risk for spontaneous bleeding
Description : The normal range of plasma copper is (A) 25–50 µg/dl (B) 50–100 µg/dl (C) 100–200 µg/dl (D) 200–400 µg/dl
Description : Renal glycosuria is characterized by (A) Hyperglycemia (B) Hyperglycemia with glycosuria (C) Normal blood glucose level with glycosuria (D) Hyperglycemia with ketosis
Description : Dip stick used for measuring the level of petro fuels (e.g. petrol, diesel, fuel oil etc.) in the storage tank is usually made of (A) Brass (B) Copper (C) High carbon steel (D) Aluminium
Last Answer : (A) Brass