Description : Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a ... is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies
Last Answer : Answers-2 Alpha Thalassaemia is due to abnormalities of the alpha chain. Persistence of HbF has survival advnatages in severely affected subjects. C-alpha 16, beta 11. e-Hb electrophoresis(Dr Shu Ho)
Description : Abnormal chain of amino acids in sickle cell anaemia is (A) Alpha chain (B) Beta chain (C) Delta chain (D) Gama chain
Last Answer : Answer : B
Description : Abnormal chain of amino acids in sickle cells anaemia is (A) Alpha chain (B) Beta chain (C) Gama chain (D) Delta chain
Description : Typically proteins do not work in their simple amino acid chain structure but instead fold and form shapes that help in their function. Which of the structures is described as being in alpha helices and beta sheets?
Last Answer : Secondary Protein Structure
Description : If the amino group and a carboxylic group of the amino acid are attached to same carbon atom, the amino acid is called as (A) Alpha (B) Beta (C) Gamma (D) Epsilon
Last Answer : Answer : A
Description : If the amino group and a carboxylic group of the amino acid are attached to same carbon atom, the amino acid is called (A) Alpha (B) Beta (C) Gamma (D) Delta
Description : Sickle cell anemia is caused a) When valine is replaced by glutamic acid in beta polypeptide chain b) When glutamic acid is replaced by valine in beta polypeptide chain c) When ... valine in alpha polypeptide chain d) When valine is replaced by glutamic acid in alpha polypeptide chain
Last Answer : b) When glutamic acid is replaced by valine in beta polypeptide chain
Description : Sulphur is made available to the body by the amino acids: (A) Cystine and methionine (B) Taurine and alanine (C) Proline and hydroxyproline (D) Arginine and lysine MINERAL METABOLISM 191
Description : Sickle cell anaemia induce to (a) change of amino acid in a-chain of haemoglobin (b) change of amino acid in b-chain of haemoglobin (c) change of amino acid in both a and b chains of haemoglobin (d) change of amino acid either a or b chains of haemoglobin.
Last Answer : (b) change of amino acid in b-chain of haemoglobin
Description : The primary structure of a protein refers to : (a) whether the protein is fibrous or globular (b) the amino acid sequence in the polypeptide chain (c) the orientation of the amino acid side chains in space (d) the presence or absence of an α-helix
Last Answer : the amino acid sequence in the polypeptide chain
Description : If the reducing equivalents enter from NAD in the respiratory chain, the phsphate/oxygen (P:O) is (A) 1 (B) 2 (C) 3 (D) 4 MINERAL METABOLISM 183
Last Answer : Answer : C
Description : Maple syrup urine diseases is an inborn error of metabolism of (A) Sulphur-containing amino acids (B) Aromatic amino acids (C) Branched chain amino acids (D) Dicarboxylic amino acids
Description : With regard to insulin: a. it is a 51 amino acid peptide b. it is formed by removal of C-chain from proinsulin c. it is produced by the alpha cells of the pancreas d. it alters the rate of enzyme synthesis
Last Answer : it alters the rate of enzyme synthesis
Description : Which of the following is the quaternary structure of proteins concerned with? (a) sequence of amino acids in the peptide chain (b) description of the way the peptide chains are arranged with ... (c) location of the disulfide bridges in the peptide chain (d) conformation of the protein backbone
Last Answer : description of the way the peptide chains are arranged with respect to each other
Description : Nonsense codons bring about (A) Amino acid activation (B) Initiation of protein synthesis (C) Termination of protein synthesis (D) Elongation of polypeptide chains
Description : Bence-Jones proteins possess all the following properties except (A) They are dimers of light chains (B) Their amino acids sequences are identical (C) Their N-terminal halves have variable amino acid sequences (D) Their C-terminal halves have constant amino acid sequences
Description : The carbon chains of prostanoic acid are bonded at the middle of the chain by a (A) 5-membered ring (B) 6-membered ring (C) 8-membered ring (D) None of these
Description : Constant segment genes of heavy chains are present in a cluster in which the first gene on side is (A) Alpha (B) Gamma (C) Delta (D) None of these
Last Answer : Answer : D
Description : Heavy chains in IgD are of following type: (A) Alpha (B) Gamma (C) Delta (D) Epsilon
Description : Light chains of immunoglobulins are of following types: (A) Alpha and kappa (B) Alpha and gamma (C) Lambda and delta(D) Kappa and lambda
Description : Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement. (a) Both are due to a quantitative defect in globin chain synthesis. (b ... problem of globin molecules. (d) Both are due to a qualitative defect in globin chain synthesis.
Last Answer : (b) Thalassemia is due to less synthesis of globin molecules
Description : Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement : (1) Both are due to a quantitative defect in globin chain synthesis (2 ... problem of globin molecules (4) Both are due to a qualitative defect in globin chain synthesis
Last Answer : (2) Thalassemia is due to less synthesis of globin molecules
Description : The end product of amino acid nitrogen metabolism in uricotelic organisms (reptiles and birds) is (A) Bilirubin (B) Urea (C) Uric acid (D) Biliverdin
Description : In human and other ureotelic organisms, the end product of amino acid nitrogen metabolism: (A) Bile acids (B) Ketone bodies (C) Urea (D) Barium sulphate
Description : An example of α-amino acid not present in proteins but essential in mammalian metabolism is (A) 3-Amino 3-hydroxypropanoic acid (B) 2-Amino 3-hydroxybutanoic acid (C) 2-Amino 4-mercaptobutanoic acid (D) 2-Amino 3-mercaptopropanoic acid
Description : An example of -amino acid not present in proteins but essential in mammalian metabolism is (A) 3-Amino 3-hydroxypropanoic acid (B) 2-Amino 3-hydroxybutanoic acid (C) 2-Amino 4-mercaptobutanoic acid (D) 2-Amino 3-mercaptopropanoic acid
Last Answer : (C) 2-Amino 4-mercaptobutanoic acid
Description : Refsum’s disease results from a defect in the following pathway except (A) Alpha-oxidation of fatty acids (B) Beta-oxidation of fatty acids (C) Gamma-oxidation of fatty acids (D) Omega-oxidation of fatty acids
Description : How alpha and beta forms of sugars are produced?
Last Answer : These are anomers. The difference lies in the spatial configuration with reference to the first carbon atom in aldoses and second carbon atom in ketoses.
Description : Side chains of all following amino acids contain aromatic rings except (A) Phenyl alanine (B) Alanine (C) Tyrosine (D) Tryptophan
Description : Side chains of all amino acids contain aromatic rings except (A) Pheynl alanine (B) Alanine (C) Tyrosine (D) Tryptophan
Description : The true statement about solutions of amino acids at physiological pH is (A) All amino acids contain both positive and negative charges (B) All amino acids contain positively charged side chains ... amino acids contain only positive charge (D) All amino acids contain negatively charged side chains
Description : Give examples of amino acids with hydropho- bic side chains.
Last Answer : Valine, leucine, isoleucine.
Description : The true statement about solutions of amino acids at physiological pH is (A) All amino acids contain both positive and negative charges (B) All amino acids contain positively charged side chains ... amino acids contain only positive Charge (D) All amino acids contain negatively charged side chains
Last Answer : (A) All amino acids contain both positive and negative charges
Description : AUG, the only identified codon for methionine is important as (A) A releasing factor for peptide chains (B) A chain terminating codon (C) Recognition site on tRNA (D) A chain initiating codon
Description : Human growth hormone has (A) One polypeptide chain and one intra-chain disulphide bond (B) One polypeptide chain and two intra-chain disulphide bond (C) Two polypeptide chains joined by one disulphide bond (D) Two polypeptide chains joined by two disulphide bond
Description : The portion of the immunoglobulin molecule that binds the specific antigen is formed by (A) Variable regions of H and L chains (B) Constant region of H chain (C) Constant region of L chain (D) Hinge region
Description : Allosteric enzymes contain (A) Multiple subunits (B) Single chain (C) Two chains (D) Three chains
Description : IgG cleaved by papain into (A) Two light and two heavy chains (B) Two Fab and one Fc fragments (C) Two pairs of one light and one heavy chain each (D) One Fab and two Fc fragments
Description : Transferrin is a type of (A) Albumin (B) α-globulin (C) β1 globulin (D) γ-globulin MINERAL METABOLISM 203
Description : Respiratory quotient of an average mixed diet is about (A) 0.65 (B) 0.7 (C) 0.75 (D) 0.85 MINERAL METABOLISM 201
Description : The total amount of iodine in the body of an average adult is (A) 10–15 mg (B) 20–25 mg (C) 45–50 mg (D) 75–100 mg MINERAL METABOLISM 199
Description : Serum inorganic phosphorous rises in all the following conditions except (A) Hypoparathyroidism (B) Hypervitaminosis D (C) Chronic renal failure (D) After a carbohydrate-rich meal MINERAL METABOLISM 197
Description : Biological value of soyabean protein is (A) 86 (B) 71 (C) 64 (D) 54 MINERAL METABOLISM 193
Description : The amount of copper in the human body is (A) 50–80 mg (B) 100–150 mg (C) 400–500 mg (D) 500–1000 mg MINERAL METABOLISM 189
Description : The immunoglobulin having highest molecular weight is (A) Ig G (B) Ig M (C) Ig E (D) Ig A MINERAL METABOLISM 187
Description : The probable cause of porphyria cutanea tarda is deficiency of (A) Uroporphyrinogen oxidase (B) Coproporphyrinogen oxidase (C) Protoporphyrinogen oxidase (D) Uroporphyrinogen I synthase MINERAL METABOLISM 185
Description : Assertion `:` Most of the human haemoglobin in our body has `2 alph` and `2 beta` polypeptide chains. Reason `:` Haemoglobin is a conjugate protein an
Last Answer : Assertion `:` Most of the human haemoglobin in our body has `2 alph` and `2 beta` polypeptide ... False. D. If both Assertion & Reason are false.
Description : In E. coli the chain initiating amino acid in protein synthesis is (A) N-formyl methionine(B) Methionine (C) Serine (D) Cysteine
Description : Maple syrup urine disease results from absence or serve deficiency of (A) Homogentisate oxidase (B) Phenylalanine hydroxylase (C) Branched chain amino acid transaminase (D) None of these
Description : The amino terminal of all polypeptide chain at the time of synthesis in E. coli is tagged to the amino acid residue: (A) Methionine (B) Serine (C) N-formyl methinine(D) N-formal serine