Description : Hinge region, the region of Ig molecule which is flexible and more exposed to enzymes is the (A) Region between first and second constant regions of H chain (domains CH1 and CH2) (B) Region between second and ... H chain (CH2 and CH3) (C) Variable regions of H chain (D) Variable regions of L chain
Last Answer : Answer : A
Description : The class specific function of the different immunoglobulin molecules is constituted by (A) Variable region of L chain (B) Constant region of H chain (C) Variable region of H chain (D) Constant region particularly CH2 and CH3 of H chain
Last Answer : Answer : D
Description : An antigen binding site on the IgG antibody is a combination of a. One variable region from a light chain and one from a heavy chain. b. Two variable regions from two light chains. c. Two ... from two heavy chains. d. One variable region from a constant region and one from a variable region.
Last Answer : a. One variable region from a light chain and one from a heavy chain.
Description : Recognition of antigen is the function of (A) Variable region of light chains (B) Variable regions of light and heavy chains (C) Constant region of heavy chains (D) Constant regions of light and heavy chains
Last Answer : Answer : B
Description : Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated? A- By rearrangements of the DNA encoding the variable regions of the heavy ... proteins can physically change their shape to bind different epitopes D- Both (a) and (b)
Last Answer : Both (a) and (b)
Description : The portion of the antigen molecule which is recognized by antibody is known as (A) Hapten (B) Epitope (C) Complement (D) Variable region
Description : The effector function of antibody is performed by (A) Variable region of light chains (B) Constant region of heavy chains (C) Variable regions of light and heavy chains (D) Constant regions of light and heavy chains
Description : An immunoglobulin molecule always contains (A) 1 κ and 3 λ type of chains (B) 2 κ and 2 λ type of chains (C) 3 κ and 1λ type of chains (D) 2 κ and 2 λ chains
Description : The variable region of heavy chains has (A) One hypervariable region (B) Two hypervariable regions (C) Three hypervariable regions (D) Four hypervariable regions
Description : The variable region of light chains has (A) One hypervariable region (B) Two hypervariable regions (C) Three hypervariable regions (D) Four hypervariable regions
Last Answer : Answer : C
Description : Which of the following statement(s) is/are true concerning the antibody response to an invading antigen? a. All antibodies are composed of one type of heavy and one type of light protein chain b. ... stimulus d. Immunoglobulins A, D, and E play an active role in the circulating humoral response
Last Answer : Answer: a Humoral defenses consist of antibody (immunoglobulin; Ig) and complement. All Ig classes (IgM, IgG, IgA, IgE, IgD) and IgG subclasses are composed of one type (M, G, A, E, D ... exist in smaller amounts in the circulation and do not appear to play a major role as host defense components
Description : Variable regions are present in (A) Immunoglobulins (B) α-Chains of T cell receptors (C) β-Chains of T cell receptors (D) All of these
Description : Bence-Jones protein is (A) An immunoglobulin (B) A dimer of heavy chains (C) A dimer of light chains (D) A dimer of one heavy and one light chains
Description : The minimum number of polypeptide chains in an immunoglobulin is (A) Two (B) Four (C) Five (D) Six
Description : Which of the following statements concerning abnormalities of the haemoglobin molecule is true? 1) Alpha thalassaemia is due to a deficiency of beta-chain production 2) HbS is caused by a ... is an adverse prognostic sign 5) oliguneoclitide probes may assist in the diagnosis of haemoglobinopathies
Last Answer : Answers-2 Alpha Thalassaemia is due to abnormalities of the alpha chain. Persistence of HbF has survival advnatages in severely affected subjects. C-alpha 16, beta 11. e-Hb electrophoresis(Dr Shu Ho)
Description : The variable region of light chains is the (A) N-terminal quarter (B) N-terminal half (C) C-terminal quarter (D) C-terminal half
Description : Which of the following is a pentameric immunoglobulin and is produced first in a primary response to an antigen
Last Answer : Which of the following is a pentameric immunoglobulin and is produced first in a primary response to an antigen A. `I_(g ... ` C. `I_(g)A` D. `I_(g)E`
Description : All immunoglobulins contain (A) 4 L chains (B) 4 H chains (C) 3 L chains (D) 2 L chains and 2 H chains
Description : Bence-Jones proteins possess all the following properties except (A) They are dimers of light chains (B) Their amino acids sequences are identical (C) Their N-terminal halves have variable amino acid sequences (D) Their C-terminal halves have constant amino acid sequences
Description : Following statements describe the characteristics of the enzyme restriction endonuclease. Identify the incorrect statement. (a) The enzyme recognises a specific palindromic nucleotide sequence in the DNA. (b) ... (d) The enzyme cuts the sugar-phosphate backbone at specific sites on each strand.
Last Answer : (c) The enzyme binds DNA at specific sites and cuts only one of the two strands.
Description : The variable region of light chain is the (A) N-terminal quarter (B) N-terminal half (C) C-terminal quarter (D) C-terminal half
Description : Erythromycin binds to 50 S ribosomal sub unit and (A) Inhibits binding of amino acyl tRNA (B) Inhibits Peptidyl transferase activity (C) Inhibits translocation (D) Causes premature chain termination
Description : eIF-4 B (A) Binds to 3’ chain initiation codon on mRNA (B) Binds to 3’ end of mRNA (C) Binds to 5’ end of mRNA (D) Unwinds mRNA near its 5’ end
Description : Antibodies contain two identical_____ chains, and two identical _____ chains. a. right, left b. constant, variable c. heavy, light d. Fab, Fc
Last Answer : c. heavy, light
Description : Antigens and haptens have the following similarity: (A) They have high molecular weights (B) They can elicit immune response by themselves (C) They can elicit an immune response only in association ... ) Once an immune response develops, free antigen and free hapten can be recognized by the antibody
Description : RNA polymerase holoenzyme binds to lac operon at the following site: (A) i gene (B) z gene (C) Operator locus (D) Promoter region
Description : All of the following statements about eukaryotic promoters are true except (A) They may be located upstream or down stream from the structural gene (B) They have two consensus sequences ( ... (D) Mutations in promoter region can decrease the efficiency of transcription of the structural gene
Description : Why is the halogenation of alkanes considered a chain reaction? (a) it occurs quickly. (b) it occurs without the generation of intermediates. (c) each step generates the reactive intermediate that causes the next step to occur. (d) the reaction allows long chains of halogenated alkanes to be formed
Last Answer : each step generates the reactive intermediate that causes the next step to occur
Description : The number of hypervariable region in H chain is (A) 1 (B) 2 (C) 3 (D) 4
Description : The number of hypervariable region in L chain is (A) 1 (B) 2 (C) 3 (D) 4
Description : A light chain gene is constructed from the following segments: (A) Variable and constant segments (B) Variable, joining and constant segments (C) Variable, diversity and constant segments (D) Variable, joining, diversity and constant segments
Description : Insulin is oxidized to separate the protein molecule into its constituent polypeptide chains without affecting the other part of the molecule by the use of (A) Performic acid (B) Oxalic acid (C) Citric acid (D) Malic acid
Description : Assertion : IgM is a type of immunoglobulin which cannot cross the placenta Reason : IgM is a pentamer immunoglobulin jointed by I-chain
Last Answer : Assertion : IgM is a type of immunoglobulin which cannot cross the placenta Reason : IgM is a ... D. If both the assertion and reason are false
Description : Which one of the following binds to specific nucleotide sequences that are upstream and most distant from the start site? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction
Description : Which one of the following binds to specific nucleotide sequences? (A) RNA polymerase (B) Repressor (C) Inducer (D) Restriction
Description : AUG, the only identified codon for methionine is important as (A) A releasing factor for peptide chains (B) A chain terminating codon (C) Recognition site on tRNA (D) A chain initiating codon
Description : Human growth hormone has (A) One polypeptide chain and one intra-chain disulphide bond (B) One polypeptide chain and two intra-chain disulphide bond (C) Two polypeptide chains joined by one disulphide bond (D) Two polypeptide chains joined by two disulphide bond
Description : In thalassemia, an amino acid is substituted in (A) Alpha chain (B) Beta chain (C) Alpha and beta chains (D) Any chain MINERAL METABOLISM 195
Description : Allosteric enzymes contain (A) Multiple subunits (B) Single chain (C) Two chains (D) Three chains
Description : The carbon chains of prostanoic acid are bonded at the middle of the chain by a (A) 5-membered ring (B) 6-membered ring (C) 8-membered ring (D) None of these
Description : IgG cleaved by papain into (A) Two light and two heavy chains (B) Two Fab and one Fc fragments (C) Two pairs of one light and one heavy chain each (D) One Fab and two Fc fragments
Description : A pre-stressed rectangular beam which carries two concentrated loads W at L/3 from either end, is provided with a bent tendon with tension P such that central one-third portion of the tendon remains parallel to the longitudinal axis, the maximum dip h is (A) WL/P (B) WL/2P (C) WL/3P (D) WL/4P
Last Answer : Answer: Option C
Description : Which of the following is exposed on the outer surface of a gram-negative bacterium?A- O-antigen of lipopolysaccharide (LPS) B- Polysaccharide portion of lipoteichoic acid (LTA) C- Braun lipoprotein D- .Electron transport system components
Last Answer : O-antigen of lipopolysaccharide (LPS)
Description : At the lowest energy level α-helix of polypeptide chain is stabilised (A) By hydrogen bonds formed between the H of peptide N and the carbonyl O of the residue (B) Disulphide bonds (C) Non polar bonds (D) Ester bonds
Description : In case of a simply supported rectangular beam of span L and loaded with a central load W, the length of elasto-plastic zone of the plastic hinge, is (A) L/2 (B) L/3 (C) L/4 (D) L/5
Last Answer : (B) L/3
Description : In case of a simply supported I-section beam of span L and loaded with a central load W, the length of elasto-plastic zone of the plastic hinge, is (A) L/2 (B) L/3 (C) L/4 (D) L/5
Last Answer : (D) L/5
Description : The number of types of H chains identified in human is (A) 2 (B) 3 (C) 4 (D) 5
Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.
Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.
Description : Adenine binds to which base in an RNA molecule?
Last Answer : ANSWER: URACIL
Description : The reduced levels of points, 30 metres apart along the longitudinal section of a road portion between chainages 5 and 9 are shown in the given figure. If there is a uniform up-gradient of the road 120 in 1, the chainage ... 15) chains (B) (6 + 12) chains (C) (6 + 18) chains (D) None of these
Last Answer : (B) (6 + 12) chains