Description : Prothrombin time remains prolonged even after parenterals administration of vitamin K in (A) Haemolytic jaundice (B) Liver damage (C) Biliary obstruction (D) Steatorrhoea
Last Answer : Answer : B
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : Fecal urobilinogen is increased in (A) Hemolytic jaundice (B) Obstruction of biliary duct (C) Extrahepatic gall stones (D) Enlarged lymphnodes
Last Answer : Answer : A
Description : Fecal urobilinogen is decreased in (A) Obstruction of biliary duct (B) Hemolytic jaundice (C) Excess fat intake (D) Low fat intake
Description : Serum lipase is increased in (A) Acute parotitis (B) Acute pancreatitis (C) Infective hepatitis (D) Biliary obstruction
Description : The presence of bilirubin in the urine without urobilinogen suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Pernicious anemia (D) Damage to the hepatic parenchyma
Description : Serum alkaline phosphatase is greatly increased in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) None of these
Last Answer : Answer : C
Description : Fecal stercobilinogen is increased in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Viral hepatitis (D) Obstructive jaundice
Description : Serum LDL has been found to be increased in (A) Obstructive jaundice (B) Hepatic jaundice (C) Hemolytic jaundice (D) Malabsorption syndrome
Description : Lesch-Nyhan syndrome, the sex linked, recessive absence of HGPRTase, may lead to (A) Compulsive self destructive behaviour with elevated levels of urate in serum (B) Hypouricemia due to liver damage (C) Failure to thrive and megaloblastic anemia (D) Protein intolerance and hepatic encephalopathy
Description : Metabolic acidosis is caused in (A) Uncontrolled diabetes with ketosis (B) Pneumonia (C) Intestinal Obstruction (D) Hepatic coma
Description : A complete absence of fecal urobilinogen is strongly suggestive of (A) Obstruction of bile duct (B) Hemolytic jaundice (C) Intrahepatic cholestasis (D) Malignant obstructive disease
Last Answer : Answer : D
Description : Which of the following processes plays the major role in terminating the action of phenobarbitone: A. Biliary excretion B. Renal excretion C. Hepatic metabolism D. Redistribution
Last Answer : B. Renal excretion
Description : Which type of jaundice in adults is the result of increased destruction of red blood cells? a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot ... is the result of liver disease. d) Non-obstructive Non-obstructive jaundice occurs with hepatitis.
Last Answer : a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot excrete the bilirubin as quickly as it is formed.
Description : Bile pigments are not present in urine in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Rotor’s syndrome
Description : kernicterus can occur in (A) Haemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) All of these
Description : Immediate direct Vanden Bergh reaction indicates (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Megalobastic anemia
Description : A mixture of conjugated and unconjugated bilirubin is found in the circulation in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Post hepatic jaundice
Description : A jaundice in which serum alanine transaminase and alkaline phosphatase are normal is (A) Hepatic jaundice (B) Hemolytic jaundice (C) Parenchymatous jaundice (D) Obstructive Jaundice
Description : Excretion of conjugated bilirubin from liver cells into biliary canaliculi is defective in (A) Gilbert’s disease (B) Crigler-Najjar syndrome (C) Lucey-Driscoll syndrome (D) Rotor’s syndrome
Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs
Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy
Description : Interleukin-6 is recognized as the cytokine primarily responsible for the alteration in hepatic protein synthesis recognized as the acute phase response. Which of the following statement(s) is/are true ... physiologic role of acute phase proteins are to reduce the systemic effects of tissue damage
Last Answer : Answer: c, d IL-6 is now recognized at the cytokine primarily responsible for the alteration in hepatic synthesis recognized as the acute phase response. Glucocorticoid hormones augment ... that generally inhibit the tissue destruction that is associated with the local initiation of inflammation
Description : Which of the following statement(s) is/are true concerning metabolic derangements in sepsis and the systemic inflammatory response syndrome which may follow progressive shock? a. Alterations in glucose ... The serum aromatic amino acids fall rapidly as they are actively used in oxidative metabolism
Last Answer : Answer: b, c A broad spectrum of metabolic abnormalities become apparent in sepsis and the systemic inflammatory response syndrome following shock. Disruption of the normal cycles of carbohydrate, ... acetyl coenzyme A. This results in reduced serum level of leucine, isoleucine and valine
Description : Anion gap is increased in (A) Renal tubular acidosis (B) Metabolic acidosis resulting from diarrhoea (C) Metabolic acidosis resulting from intestinal obstruction (D) Diabetic ketoacidosis
Description : Metabolic alkalosis occurs (A) As consequence of high intestinal obstruction (B) In central nervous system disease (C) In diarrhoea (D) In colitis
Description : Which of the following terms refers to enlarged, red, and tender lymph nodes? a) Lymphadenitis Acute lymphadenitis is demonstrated by enlarged, red and tender lymph nodes. b) Lymphangitis ... refers to a condition in which chronic swelling of the extremity recedes only slightly with elevation.
Last Answer : a) Lymphadenitis Acute lymphadenitis is demonstrated by enlarged, red and tender lymph nodes.
Description : Oral neomycin is beneficial in hepatic coma because: A. In hepatic failure patients it is absorbed from the intestines B. It decreases ammonia production by gut bacteria C. It reacts chemically with ... gut to prevent its diffusion into blood D. It induces ammonia detoxifying enzymes in the liver
Last Answer : B. It decreases ammonia production by gut bacteria
Description : Which of the following concerning the conjugation of bilirubin is correct? 1) is catalysed by a glucuronyl transferase 2) occurs in the Kupfer cells of the liver 3) is increased by valproate 4) is inhibited by rifampicin 5) is impaired in Dubin-Johnson syndrome
Last Answer : Answers-1 b - Hepatocytes. c - Enzyme inhibitor. d - Enzyme inducer. e - Conjugation is OK but excretion from the hepatocyte into the bile is impaired. (Gilbert's syndrome ... bilirubinaemia. Dubin-Johnson syndrome - bilirubin can't Depart from the hepatocyte - conjugated bilirubinaemia.)
Description : Growth hormone causes hyperglycemia. It is a result of (A) Decreased peripheral utilization of glucose (B) Decreased hepatic production via gluconeogenesis (C) Increased glycolysis in muscle (D) Decrersed lipolysis
Description : Hepatic glycogenoloysis is increased by (A) Insulin (B) Glucagon (C) Epinephrine (D) Glucocorticoids ENZYMES 163
Description : Ketosis reflects (A) Increased hepatic glucose liberation (B) Increased fatty acid oxidation (C) Increased carbohydrate utilisation (D) Incresed gluconeogenesis
Description : In obstructive jaundice, faecal urobilinogen is (A) Absent (B) Decreased (C) Increased (D) Normal
Description : In hemolytic jaundice, bilirubin in urine is (A) Usually absent (B) Usually present (C) Increased very much (D) Very low
Description : In obstructive jaundice, urinary bilirubin is (A) Absent (B) Increased (C) Present (D) Present in small amount
Description : Bile pigments are absent and urobilinogen increased in urine in (A) Haemolytic jaundice (B) Hepatocellular jaundice (C) Obstructive jaundice (D) Rotor’s syndrome
Description : Increased serum ornithine carabamoyl transferase activity is diagnostic of (A) Myocardial infarction (B) Hemolytic jaundice (C) Bone disease (D) Acute viral hepatitis
Description : Hepatocellular jaundice as compared to pure obstructive type of jaundice is characterized by (A) Increased serum alkaline phosphate, LDH and ALT (B) Decreased serum alkaline phosphatase, LDH and ALT (C ... levels of LDH and ALT (D) Decreased serum alkaline phosphatase and increased serum LDH and ALT
Description : Increased urobilinogen in urine and absence of bilirubin in the urine suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Viral hepatitis (D) Toxic jaundice
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Description : An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis
Description : Kehr’s sign is a classical feature of Options: 1) Rupture of liver 2) Acute pancreatitis 3) Acute intestinal obstruction 4) Rupture of spleen
Last Answer : Correct Answer: 4) Rupture of spleen
Description : Which of the following features would be expected on lipid analysis in a 57 year old female with two year history of primary biliary cirrhosis? 1) A lipaemic appearance of the serum would be ... xanthomas 5) No evidence of a dyslipidaemia would be expected with this short a duration of disease
Last Answer : Answers-4 In prolonged cholestasis features include: increased serum cholesterol, a moderate increase in triglyceride, the serum is not lipaemic, and reduced HDL levels. Clinical features include: ... persisted for more than 3 months sometimes fat deposits may involve bone and peripheral nerves.
Description : When the clearance above the obstruction is equal to the radii of even Fresnel zone at the point of reflection the RSL A. remains the same B. is above threshold C. is decreased D. is increased
Last Answer : C. is decreased
Description : Which of the following statements about the presence of gallstones in diabetes patients is/are correct? A. Gallstones occur with the same frequency in diabetes patients as in the ... have prompt elective cholecystectomy, to avoid the complications of acute cholecystitis and gallbladder necrosis.
Last Answer : Answer: E DISCUSSION: Gallstones have been found to be very prevalent in patients with type II (non-insulin-dependent) diabetes mellitus, perhaps related to the dyslipoproteinemia in ... added mortality associated with it. There is no causal relationship between diabetes and pancreatic cancer
Description : Which of the following terms refers to lung tissue that has become more solid in nature due to a collapse of alveoli or infectious process? a) Consolidation Consolidation occurs during an ... chronic infection. d) Empyema Empyema refers to accumulation of purulent material in the pleural space.
Last Answer : a) Consolidation Consolidation occurs during an infectious process such as pneumonia.
Description : Select the correct statement . (a) Salivery glands situated just outside the buccal cavity. (b) Liver is the largest digestive gland. (c ) Hepatic duc
Last Answer : Select the correct statement . (a) Salivery glands situated just outside the buccal cavity. (b) Liver is the largest ... C. b,c & d D. a,b & c
Description : The blood vessel which carries oxygenated blood to the liver is – (1) Coronary Artery (2) PulmonawArtety (3) Carotid Artery (4) Hepatic Artery
Last Answer : (4) Hepatic Artery Explanation: In anatomy, the common hepatic artery is a short blood vessel that supplies oxygenated blood to the liver, pylorus (a part of the stomach), duodenum (a part of the small intestine) and pancreas.
Description : What is the name of vessel that delivers the nutrient rich blood from the stomach and small intestine to the liver? (1) left hepatic artery (2) Hepatic vein (3) Right hepatic artery (4) Hepatic portal vein
Last Answer : (4) Hepatic portal vein Explanation: The portal vein or hepatic portal vein is a blood vessel that carries blood from the gastrointestinal tract, gallbladder, pancreas and spleen to the liver.
Description : The circulatory route that runs from the digestive tract to the liver is called: B A. Cornnary circulation B. Hepatic portal circulation C. Pulmonary circulation D. Systemic circulation
Last Answer : Hepatic portal circulation