Description : All the following statements about TSH are true except (A) It is a tropic hormone (B) It acts on para-follicular cells of thyroid glands (C) Its receptors are membrane-bound (D) Its second messenger is cyclic AMP
Last Answer : Answer : B
Description : Cyclic AMP acts as the second messenger for all of the following except (A) Oxytocin (B) TSH (C) ACTH (D) FSH 216 MCQs IN BIOCHEMISTRY
Last Answer : Answer : A
Description : The second messenger for many hormones is (A) ATP (B) cyclic AMP (C) cGMP (D) UTP HORMONE METABOLISM 227
Description : The second messenger for glucocorticoids is (A) Cyclic AMP (B) Cyclic GMP (C) Inositol triphosphate (D) No second messenger is required
Last Answer : Answer : D
Description : Second messenger for glucagons is (A) Cyclic AMP (B) Diacylglycerol (C) Cyclic GMP (D) Inositol triphosphate
Description : The second messenger for PTH is (A) Cyclic AMP (B) Cyclic GMP (C) Diacylglycerol (D) Inositol triphosphate
Description : All the following statements about steroid hormones are true except (A) They are hydrophobic (B) They require carriers to transport them in circulation (C) Their receptors are intracellular (D) They require cyclic AMP as second messenger
Description : Cyclic GMP acts as the second messenger for (A) Nerve growth factor (B) Atrial natriuretic factor (C) Epinephrine (D) Norepinephrine
Description : Identify A, B and C in the diagramatic representation of the mechanism of hormone action. B A Response 1 C Physiological Responses Select the correct option from the following. (a) A-Steroid Hormone; B- ... ; C - Second Messenger (d) A-Protein Hormone; B-Cyclic AMP; C-Hormone-receptor Complex
Last Answer : (b) A-Protein Hormone; B-Receptor; C-Cyclic AMP
Description : How does steroid hormone influence the cellular activities? (a) Using aquaporin channels ‘as second messenger’ (b) Changing the permeability of the cell membrane (c) Binding to DNA and forming a gene-hormone complex (d) Activating cyclic AMP located on the cell membrane
Last Answer : (c) Binding to DNA and forming a gene-hormone complex
Description : Which does NOT occur in a cell stimulated by a steroid hormone? A) The steroid hormone enters the cell by crossing the plasma membrane. B) The hormone binds to a receptor molecule in the ... activates certain genes. E) DNA is transcribed, mRNA is translated, and the result is protein synthesis.
Last Answer : C) The second messenger cyclic AMP is stimulated by the hormone-receptor complex. D) The hormone-receptor complex binds the chromatin and activates certain genes.
Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane
Last Answer : C) production of new proteins
Description : The best understood intracellular messenger is cyclic AMP (cAMP). Which of the following statement(s) concerning this intracellular messenger is/are correct? a. Intracellular cyclic AMP is constantly ... of adenylate cyclase d. cAMP is the only cyclic nucleotide active as an intracellular messenger
Last Answer : Answer: a, b The prototypic intracellular messenger is cAMP. To function as a mediator, the concentration of cAMP must change rapidly. In resting cells, cAMP is continuously being degraded by ... produce cGMP. Intracellular calcium ions also serve as second messengers in a large number of cells
Description : All the following hormones use cAMP as a second messenger except (A) Estrogen (B) FSH (C) Luteinizing (D) Glucagon
Description : Which ONE of the following is true concerning Antidiuretic hormone(ADH)? 1) Carbamazepine potentiates it's release 2) Ethanol potentiates it's release 3) It circulates in the blood bound to neurohypophysin 4) It is a cyclic octapeptide 5) It is synthesised in the posterior pituitary
Last Answer : Answers-1 ADH is a nonapeptide manufactured in the paraventricular and supra-optic nuclei of the hypothalamus and released from the posterior pituitary. It acts on the collecting ducts improving ... agents such as thiazides and SSRIs may potentiate its release. Ethanol usually inhibits release.
Description : The following are true about parathyroid hormone a. it is an 84 amino acid peptide hormone b. it increases calcium absorption from the gastrointestinal tract c. it acts on a cell surface receptor that increases intracellular cyclic AMP d. all above
Last Answer : all above
Description : With regard to membrane receptors for hormones: a. they are often glycoproteins b. they are important for hormones made up of steroid c. those for insulin exhibit an intrinsic protein kinase activity d. glucagon uses calcium as a second messenger
Last Answer : they are often glycoproteins
Description : Given below is an incomplete table on hormones, their source glands and one major effect of each human body. Identify the option representing correct grouping of hormone its gland and ... hormone (b) Placenta Insulin Vasopressin (c) Ovary Insulin Calcitonin (d) Placenta Glucagon Calcitonin
Last Answer : (a) Ovary Glucagon Growth hormone
Description : Which of the following pairs of hormones are not antagonistic (having opposite effects) to each other? (a) Aldosterone Atrial Natriuretic Factor (b) Relaxin Inhibin (c) Parathormone Calcitonin (d) Insulin Glucagon
Last Answer : (b) Relaxin Inhibin
Description : A 55-year-old male undergoes a total abdominal colectomy. Which of the following statement(s) is/are true concerning the hormonal response to the surgical procedure? a. Adrenocorticotropic ... in serum insulin and a fall in glucagon accelerate hepatic glucose production and maintain gluconeogenesis
Last Answer : Answer: a, c One of the earliest consequence of a surgical procedure is the rise in levels of circulating cortisol that occur in response to a sudden outpouring of ACTH ... hepatic glucose production, and, with other hormones (epinephrine and glucocorticoids), gluconeogenesis is maintained
Description : Dipalmitoyl lecithin acts as (A) Platelet activating factor (B) Second messenger for hormones (C) Lung surfactant (D) Anti-ketogenic compound
Last Answer : Answer : C
Description : All of the following subserve as intracellular second messengers in receptor mediated signal transduction except: A. Cyclic AMP B. Inositol trisphosphate C. Diacyl glycerols D. G proteins
Last Answer : D. G proteins
Description : Enhanced facultative reabsorption of water by Vasopressin is mediated by (A) Cyclic AMP (B) Ca++ (C) Cyclic GMP (D) Mg++
Description : All following are naturally occurring nucleotides except (A) Cyclic AMP (B) ATP (C) DNA (D) Inosine monophosphate
Description : Cyclic AMP can be formed from (A) AMP (B) ADP (C) ATP (D) All of these
Description : ADP ribosylation is the mode of action of (A) Cholera toxin (B) Acetyl choline (C) Muscerinic receptors (D) Cyclic AMP
Description : Protein kinase C is activated by (A) Cyclic AMP (B) Cyclic GMP (C) Diacyl glycerol (D) Inositol triphosphate
Description : ACTH induces rise in (A) Cyclic AMP (B) Cyclic GMP (C) Calcium (D) Magnesium
Description : Cyclic AMP binds to (A) Catalytic subunits of protein kinase (B) Regulatory subunits of protein kinase (C) Catalytic subunits of phosphorylase kinase (D) Regulatory subunits of phosphorylase kinase
Description : Action of glycogen synthase is inhibited by (A) Insulin (B) Glucose (C) Mg2+ (D) Cyclic AMP
Description : Cyclic AMP is formed from ATP by the enzyme adenylate cyclase which is activated by the hormone: (A) Insulin (B) Epinephrine (C) Testosterone (D) Progesterone
Last Answer : B
Description : Glycogen synthetase activity is depressed by (A) Glucose (B) Insulin (C) Cyclic AMP (D) Fructokinase
Last Answer : C
Description : It is unique that the following single antidiabetogenic hormone effectively counter acts the several diabetogenic hormones: (A) Glucagon (B) Glucocorticoids (C) Insulin (D) Growth hormone
Description : What is ADH acts on
Last Answer : ADH acts on A. Collecting tubule of kidney B. Loop of Henle C. Collecting ducts of tests D. None of the above
Description : Atropine is contraindicated in (a) Cyclic AMP (b) Inositol trisphosphate (c) Diacyl glycerols (d) G protein
Last Answer : Ans: D
Description : Organic nitrates relax vascular smooth muscle by (a) Increasing intracellular cyclic AMP (b) Increasing intracellular cyclic GMP (c) Decreasing intracellular cyclic AMP (d) Both (b) and (c)
Last Answer : Ans: B
Description : Which of the following does not act interacellularly to produce physiologic effects a. Triiodothyronine b. Inositol triphosphate c. Aldosterone d. Cyclic AMP e. Doapamine
Last Answer : Doapamine
Description : Which statement is NOT true about non-steroid (peptide) hormones? A) They are derived from peptides, proteins, polypeptides, and derivatives of amino acids. B) They bind to receptors on the cell surface. ... They create an enzyme cascade effect. E) They enter the cell in order to have an effect.
Last Answer : E) They enter the cell in order to have an effect.
Description : Cyclic nucleotides exert the following action on salt transport across intestinal mucosal cells: A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 - secretion B. Cyclic AMP enhances but cyclic GMP ... Cl- reabsorption D. Both cyclic AMP and cyclic GMP enhance Na+ and Cl- reabsorption
Last Answer : A. Both cyclic AMP and cyclic GMP enhance Cland HCO3 – secreti
Description : The following drug increases cyclic-AMP in platelets and inhibits their aggregation without altering levels of thromboxane A2 or prostacyclin: A. Aspirin B. Sulfinpyrazone C. Dipyridamole D. Abciximab
Last Answer : C. Dipyridamole
Description : Aspirin prolongs bleeding time by inhibiting the synthesis of: A. Clotting factors in liver B. Prostacyclin in vascular endothelium C. Cyclic AMP in platelets D. Thromboxane A2 in platelets
Last Answer : D. Thromboxane A2 in platelets
Description : Organic nitrates relax vascular smooth muscle by: A. Increasing intracellular cyclic GMP B. Increasing intracellular cyclic AMP C. Decreasing intracellular cyclic AMP D. Both ‘A’ and ‘C’ are correct
Last Answer : A. Increasing intracellular cyclic GMP
Description : 6.4 Several actions of growth hormone are exerted through the elaboration of: A. Cyclic AMP B. Cyclic GMP C. Somatostatin D. Insulin like growth factor-1
Last Answer : D. Insulin like growth factor-1
Description : The receptor transduction mechanism with the fastest time-course of response effectuation is: A. Adenylyl cyclase-cyclic AMP pathway B. Phospholipase C-IP3: DAG pathway C. Intrinsic ion channel operation D. Protein synthesis modulation
Last Answer : C. Intrinsic ion channel operation
Description : The secondary messenger which show antagonistic effect to c-AMP in heart muscle is
Last Answer : The secondary messenger which show antagonistic effect to c-AMP in heart muscle is A. `Ca^(2+)` B. Inositol triphosphate `(IP_3)` C. DAG D. c-GMP
Description : Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and utilisation. (a) Insulin (b) Glucagon (c) Secretin (d) Gastrin
Last Answer : (a) Insulin
Description : Select the correct statement. (a) Glucocorticoids stimulate gluconeogenesis. (b) Glucagon is associated with hypoglycemia. (c) Insulin acts on pancreatic cells and adipocytes. (d) Insulin is associated with hyperglycemia
Last Answer : (a) Glucocorticoids stimulate gluconeogenesis.
Description : Hormonal stimulation of the formation of the second messenger inositol 1,4,5 triphosphate (IP3) quickly leads to the release of which other intracellular messenger? (A) cAMP (B) Prostaglandin (C) Calcinon (D) Leukotriene
Description : One of the following is not used as a second messenger by hormones: (A) mRNA (B) cAMP (C) Calcium ions (D) Myoinisotol 1, 4, 5 triphosphate