Description : Acyl carrier protein is involved in the synthesis of (A) protein (B) glycogen (C) fatty acid outside the mitochondria (D) fatty acid in the mitochondria
Last Answer : Answer : C
Description : Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) ... result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin
Description : Insulin decreases the synthesis of (A) Hexokinase (B) Glucokinase (C) PEP carboxykinase (D) Glycogen synthetase
Description : Insulin regulates fatty acid synthesis by (A) Dephosphorylating of acetyl CoA carboxylase (B) Activating phosphorylase (C) Inhibiting malonyl CoA formation (D) Controlling carnitine-Acyl CoA transferase activity
Last Answer : Answer : A
Description : What is the action of insulin on fatty acid synthesis?
Last Answer : Insulin favours lipogenesis.
Description : Glycogenin is (A) Uncoupler of oxidative phosphorylation (B) Polymer of glycogen molecules (C) Protein primer for glycogen synthesis (D) Intermediate in glycogen breakdown
Last Answer : C
Description : All the following statements about acetyl CoA carboxylase are true except (A) It is required for de novo synthesis of fatty acids (B) It is required for mitochondrial elongation of fatty acids ( ... for microsomal elongation of fatty acids (D) Insulin converts its inactive form into its active form
Last Answer : Answer : B
Description : De novo synthesis and oxidation of fatty acids differ in the following respect: (A) Synthesis occurs in cytosol and oxidation in mitochondria (B) Synthesis is decreased and oxidation increased by ... synthesis and FAD in oxidation (D) Malonyl CoA is formed during oxidation but not during synthesis
Description : Action of Insulin does not include the following: A. Facilitation of glucose transport into cells B. Facilitation of glycogen synthesis by liver C. Facilitation of neoglucogenesis by liver D. Inhibition of lipolysis in adipose tissue
Last Answer : . Facilitation of neoglucogenesis by liver
Description : Epinephrine increases the concentration of free fatty acids in plasma by increasing (A) Extramitochondrial fatty acid synthesis (B) Mitochondrial fatty acid chain elongation (C) Microsomal fatty acid chain elongation (D) Lipolysis in adipose tissue
Last Answer : Answer : D
Description : Select the correct matching in the following pairs. (a) Rough ER – Synthesis of glycogen (b) Rough ER – Oxidation of fatty acids (c) Smooth ER – Oxidation of phospholipids (d) Smooth ER – Synthesis of lipids
Last Answer : (d) Smooth ER – Synthesis of lipids
Description : Insulin: a. is secreted as a pro-insulin b. increases protein synthesis c. is required for glucose uptake in all tissues d. is a steroid hormone
Last Answer : is secreted as a pro-insulin
Description : Which of the following represents the action of insulin? (a) Increases blood glucose level by stimulating glucagon production. (b) Decreases blood glucose levels by forming glycogen. (c) ... promoting cellular uptake of glucose. (d) Increases blood glucose levels by hydrolysis of glycogen.
Last Answer : (b) Decreases blood glucose levels by forming glycogen
Description : Uridine diphosphate glucose (UDPG) is (A) Required for metabolism of galactose (B) Required for synthesis of glucuronic acid (C) A substrate for glycogen synthetase (D) All of the above
Last Answer : D
Description : Adrenaline: a. is synthesized by demethylation of noradrenaline b. increases coronary blood flow c. increases free fatty acids in the blood d. mobilizes glycogen stores from the liver
Last Answer : increases coronary blood flow
Description : Action of insulin on lipid metabolism is (A) It increases lipolysis and increases triglyceride synthesis (B) It decreases lipolysis and increases triglyceride synthesis (C) It decreases ... and decreases triglyceride synthesis (D) It increases synthesis of triglyceride and increased ketogenesis
Description : The effects of glucocorticoid hormones include: a. increase hepatic glycogen synthesis b. decrease glucose uptake by the adipose tissue c. decrease hepatic gluconeogesis d. increase protein synthesis in the skeletal muscles
Last Answer : . increase hepatic glycogen synthesis
Description : Rough endoplasmic reticulum is involved in the synthesis of a. glycogen b. protein c. steroids d. lipids
Last Answer : protein
Description : Insulin has no effect on the activity of the enzyme: (A) Glycogen synthetase (B) Fructokinase (C) Pyruvate kinase (D) Pyruvate dehydrogenase
Description : The hormone activating the glycogen synthase activity is (A) Insulin (B) Glucagon (C) Epinephrine (D) ACTH
Description : Action of glycogen synthase is inhibited by (A) Insulin (B) Glucose (C) Mg2+ (D) Cyclic AMP
Description : One of the following statement is correct: (A) Glycogen synthase ‘a’ is the phosphorylated (B) cAMP converts glycogen synthase b to ‘a’ (C) Insulin converts glycogen synthase b to a (D) UDP glucose molecules interact and grow into a Glycogen tree
Description : Glycogen synthetase activity is depressed by (A) Glucose (B) Insulin (C) Cyclic AMP (D) Fructokinase
Description : The desaturation and chain elongation system of polyunsaturated fatty acid are enhanced by (A) Insulin (B) Glucagon (C) Epinephrine (D) Thyroxine
Description : Complete hydrolysis of proteins produces : (a) Ammonia and carbon dioxide (b) Urea and uric acid (c) A mixture of amino acids (d) Glycogen and a fatty acid
Last Answer : A mixture of amino acids
Description : In the synthesis of glycogen from glucose the reversible step is (A) Glucose → glucose 6-phosphate (B) Glucose 6-phosphate → glucose 1-phosphate (C) Glucose 1-phosphate → UDP glucose (D) UDP glucose → glycogen
Description : In the glycogen synthesis, which is the active glucose derivative?
Last Answer : UDP-glucose.
Description : The enzyme regulating extramitochondrial fatty acid synthesis is (A) Thioesterase (B) Acetyl CoA carboxylase (C) Acyl transferase (D) Multi-enzyme complex
Description : A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is (A) Biotin (B) FMN (C) NAD (D) NADP
Description : Vitamin K is a cofactor for (A) Gamma carboxylation of glutamic acid residue (B) β-Oxidation of fatty acid (C) Formation of γ-amino butyrate (D) Synthesis of tryptophan
Description : Intermediate in the denovo synthesis of triacyl glycerols include all the following except (A) Fatty acyl CoA (B) CDP diacyl glycerol (C) Glycerol-3-phosphate (D) Lysophosphatidic acid
Description : Acetyl CoA required for extra mitochondrial fatty acid synthesis is produced by (A) Pyruvate dehydrogenase complex (B) Citrate lyase (C) Thiolase (D) Carnitine-acyl transferase
Description : All statements regarding 3-OH-3 methyl glutaryl CoA are true except (A) It is formed in the cytoplasm (B) Required in ketogenesis (C) Involved in synthesis of Fatty acid (D) An intermediate in cholesterol biosynthesis
Description : Which of the following cofactors or their derivatives must be present for the conversion of acetyl CoA to malonyl CoA extramitochondrial fatty acid synthesis? (A) Biotin (B) FAD (C) FMN (D) ACP
Description : A pathway that requires NADPH as a cofactor is (A) Fatty acid oxidation (B) Extra mitochondrial denovo fatty acid synthesis (C) Ketone bodies formation (D) Glycogenesis
Description : Fatty acid synthesis takes place in the presence of the coenzyme: (A) NAD+ (B) Reduced NAD (C) NADP+ (D) Reduced NADP
Description : For extramitochondrial fatty acid synthesis, acetyl CoA may be obtained from (A) Citrate (B) Isocitrate (C) Oxaloacetate (D) Succinate
Description : NADPH required for fatty acid synthesis can come from (A) Hexose monophosphate shunt (B) Oxidative decarboxylation of malate (C) Extramitochondrial oxidation of isocitrate (D) All of these
Description : One functional sub-unit of multi-enzyme complex for de novo synthesis of fatty acids contains (A) One —SH group (B) Two —SH groups (C) Three —SH groups (D) Four —SH groups FATS AND FATTY ACID METABOLISM 87
Description : Acetyl CoA carboxylase regulates fatty acid synthesis by which of the following mechanism? (A) Allosteric regulation (B) Covalent modification (C) Induction and repression (D) All of these
Description : De novo synthesis of fatty acids requires all of the following except (A) Biotin (B) NADH (C) Panthothenic acid (D) ATP
Description : Which of the following is required as a reductant in fatty acid synthesis? (A) NADH (B) NADPH (C) FADH2 (D) FMNH2
Description : Deficiency of biotin results in decrease in (A) Amino acid synthesis (B) Lipid synthesis (C) Kidney (D) Fatty acid synthesis
Description : For synthesis of prostaglandins, the essential fatty acids give rise to a fatty acid containing (A) 12 carbon atoms (B) 16 carbon atoms (C) 20 carbon atoms (D) 24 carbon atoms
Description : Acetyl CoA is not used for the synthesis of (A) Fatty acid (B) Cholesterol (C) Pyruvic acid (D) Citric acid
Description : How is fatty acid synthesis regulated?
Last Answer : Key enzyme, acetyl CoA carboxylase, is stimulated by citrate and inhibited by palmitoyl CoA.
Description : What are the sources of NADPH for fatty acid synthesis?
Last Answer : Glucose-6-phosphate dehydrogenase, malic enzyme, cytoplasmic malate dehydrogenase.
Description : What are the steps in which NADPH is used in fatty acid synthesis?
Last Answer : Step 4 (Keto acyl reductase) and Step 6 (Enoyl reductase).
Description : Acetyl CoA from mitochondria is transferred to cytoplasm for the de novo synthesis of fatty acid, by which enzyme?
Last Answer : ATP citrate lyase.
Description : What is the rate limiting enzyme of de novo synthesis of fatty acid?
Last Answer : Acetyl CoA carboxylase.