The common features of introns include all the following except (A) The base sequence begins with GU (B) The base sequence ends with AG (C) The terminal AG sequence is preceded by a purine rich tract of ten nucleotides (D) An adenosine residue in branch site participates in splicing

The common features of introns include all the following except (A) The base sequence begins with GU (B) The base sequence ends with AG (C) The terminal AG sequence is preceded by a purine rich tract of ten nucleotides (D) An adenosine residue in branch site participates in splicing
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Answer :  C
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True statements about the nucleic acid include: a. contains purine and pyrimidine which are bound together by covalent bonds b. there is always an equal concentration of purine and pyrimidine c. in RNA, thymine is replaced by uracil d. introns is more common than exons on the DNA e. the histones mark the excision site

Description : True statements about the nucleic acid include: a. contains purine and pyrimidine which are bound together by covalent bonds b. there is always an equal concentration of purine and pyrimidine c. in RNA, ... d. introns is more common than exons on the DNA e. the histones mark the excision site

Last Answer : there is always an equal concentration of purine and pyrimidine

In the regulation of genes: a. more than 90% of the base sequences in human DNA have not known function b. extrons are the part of the gene that code for amino acids found in the final proteins. c. introns usually begins with the nucleotide sequence GT d. all above

Description : In the regulation of genes: a. more than 90% of the base sequences in human DNA have not known function b. extrons are the part of the gene that code for amino acids found in the final proteins. c. introns usually begins with the nucleotide sequence GT d. all above

Last Answer : all above

Post-transcriptional modification of hnRNA involves all of the following except (A) Addition of 7-methylguanosine triphosphate cap (B) Addition of polyadenylate tail (C) Insertion of nucleotides (D) Deletion of introns

Description : Post-transcriptional modification of hnRNA involves all of the following except (A) Addition of 7-methylguanosine triphosphate cap (B) Addition of polyadenylate tail (C) Insertion of nucleotides (D) Deletion of introns

Last Answer : Answer : C

In the pathway of de novo synthesis of purine nucleotides, all the following are allosteric enzymes except (A) PRPP glutamyl amido transferase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) Adenylosuccinase

Description : In the pathway of de novo synthesis of purine nucleotides, all the following are allosteric enzymes except (A) PRPP glutamyl amido transferase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) Adenylosuccinase

Last Answer : Answer : D

The enzyme common to catabolism of all the purines is (A) Adenosine deaminase (B) Purine nucleoside phosphorylase (C) Guanase (D) None of these

Description : The enzyme common to catabolism of all the purines is (A) Adenosine deaminase (B) Purine nucleoside phosphorylase (C) Guanase (D) None of these

Last Answer : Answer : B

The normal function of restriction endonucleases is to (A) Excise introns from hrRNA (B) Polymerize nucleotides to form RNA (C) Remove primer from okazaki fragments (D) Protect bacteria from foreign DNA

Description : The normal function of restriction endonucleases is to (A) Excise introns from hrRNA (B) Polymerize nucleotides to form RNA (C) Remove primer from okazaki fragments (D) Protect bacteria from foreign DNA

Last Answer : Answer : D

Removal of introns and joining of exons in a defined order during transcription is called (a) looping (b) inducing (c) slicing (d) splicing

Description : Removal of introns and joining of exons in a defined order during transcription is called (a) looping (b) inducing (c) slicing (d) splicing

Last Answer : (a) looping

Removal of introns and joining of exons in a defined order during transcription is called (a) looping (b) inducing (c) slicing (d) splicing

Description : Removal of introns and joining of exons in a defined order during transcription is called (a) looping (b) inducing (c) slicing (d) splicing

Last Answer : d) splicing.

What is true about ribosomes? (a) The prokaryotic ribosomes are 80S, where “S” stands for sedimentation coefficient. (b) These are composed of ribonucleic acid and proteins. (c) These are found only in eukaryotic cells. (d) These are self-splicing introns of some RNAs

Description : What is true about ribosomes? (a) The prokaryotic ribosomes are 80S, where “S” stands for sedimentation coefficient. (b) These are composed of ribonucleic acid and proteins. (c) These are found only in eukaryotic cells. (d) These are self-splicing introns of some RNAs

Last Answer : (b) These are composed of ribonucleic acid and proteins.

What is true about ribosomes ? (1) These are self - splicing introns of some RNAs (2) The prokaryotic ribosomes are 80S, where “S” stands for sedimentation coefficient (3) These are composed of ribonucleic acid and proteins (4) These are found only in eukaryotic cells

Description : What is true about ribosomes ? (1) These are self - splicing introns of some RNAs (2) The prokaryotic ribosomes are 80S, where “S” stands for sedimentation coefficient (3) These are composed of ribonucleic acid and proteins (4) These are found only in eukaryotic cells

Last Answer : (3) These are composed of ribonucleic acid and proteins

Mammals other than higher primates do not suffer from gout because they (A) Lack xanthine oxidase (B) Lack adenosine deaminase (C) Lack purine nucleoside phosphorylase (D) Possess uricase

Description : Mammals other than higher primates do not suffer from gout because they (A) Lack xanthine oxidase (B) Lack adenosine deaminase (C) Lack purine nucleoside phosphorylase (D) Possess uricase

Last Answer : Answer : D

Salvage of purine bases is regulated by (A) Adenosine phosphoribosyl transferase (B) Hypoxanthine guanine phosphoribosyl transferase (C) Availability of PRPP (D) None of these

Description : Salvage of purine bases is regulated by (A) Adenosine phosphoribosyl transferase (B) Hypoxanthine guanine phosphoribosyl transferase (C) Availability of PRPP (D) None of these

Last Answer : Answer : C

In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Description : In inherited deficiency of hypoxanthine guanine phosphoribosyl transferase (A) De novo synthesis of purine nucleotides is decreased (B) Salvage of purines is decreased (C) Salvage of purines is increased (D) Synthesis of uric acid is decreased

Last Answer : Answer : B

The available PRPP is used preferentially for (A) De novo synthesis of purine nucleotides (B) De novo synthesis of pyrimidine nucleotides (C) Salvage of purine bases (D) Salvage of pyrimidine bases

Description : The available PRPP is used preferentially for (A) De novo synthesis of purine nucleotides (B) De novo synthesis of pyrimidine nucleotides (C) Salvage of purine bases (D) Salvage of pyrimidine bases

Last Answer : Answer : C

5-Phosphoribosyl-1-pyrophosphate is required for the synthesis of (A) Purine nucleotides (B) Pyrimidine nucleotides (C) Both (A) and (B) (D) None of these

Description : 5-Phosphoribosyl-1-pyrophosphate is required for the synthesis of (A) Purine nucleotides (B) Pyrimidine nucleotides (C) Both (A) and (B) (D) None of these

Last Answer : Answer : C

For de novo synthesis of purine nucleotides, aspartate provides (A) Nitrogen 1 (B) Nitrogen 3 (C) Nitrogen 7 (D) Nitrogen 9

Description : For de novo synthesis of purine nucleotides, aspartate provides (A) Nitrogen 1 (B) Nitrogen 3 (C) Nitrogen 7 (D) Nitrogen 9

Last Answer : Answer : A

For de novo synthesis of purine nucleotides, glycine provides (A) One nitrogen atom (B) One nitrogen and one carbon atom (C) Two carbon atoms (D) One nitrogen and two carbon atoms

Description : For de novo synthesis of purine nucleotides, glycine provides (A) One nitrogen atom (B) One nitrogen and one carbon atom (C) Two carbon atoms (D) One nitrogen and two carbon atoms

Last Answer : Answer : D

The nitrogen atoms for de novo synthesis of purine nucleotides are provided by (A) Aspartate and glutamate (B) Aspartate and glycine (C) Aspartate, glutamine and glycine (D) Aspartate, glutamate and glycine

Description : The nitrogen atoms for de novo synthesis of purine nucleotides are provided by (A) Aspartate and glutamate (B) Aspartate and glycine (C) Aspartate, glutamine and glycine (D) Aspartate, glutamate and glycine

Last Answer : Answer : C

In the biosynthesis of purine nucleotides the AMP feed back regulates (A) Adenylosuccinase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) HGPR Tase

Description : In the biosynthesis of purine nucleotides the AMP feed back regulates (A) Adenylosuccinase (B) Adenylosuccinate synthetase (C) IMP dehydrogenase (D) HGPR Tase

Last Answer : Answer : B

An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase

Description : An enzyme which acts as allosteric regulator and sensitive to both phosphate concentration and to the purine nucleotides is (A) PRPP synthetase (B) PRPP glutamyl midotransferase (C) HGPR Tase (D) Formyl transferase

Last Answer : Answer : A

Ultraviolet light can damage a DNA strand causing (A) Two adjacent purine residue to form a covalently bounded dimer (B) Two adjacent pyrimidine residues to form covalently bonded dimer (C) Disruption of phosphodiesterase linkage (D) Disruption of non-covalent linkage

Description : Ultraviolet light can damage a DNA strand causing (A) Two adjacent purine residue to form a covalently bounded dimer (B) Two adjacent pyrimidine residues to form covalently bonded dimer (C) Disruption of phosphodiesterase linkage (D) Disruption of non-covalent linkage

Last Answer : Answer : B

Although each specific tRNA differs from the others in its sequence of nucleotides, all tRNA molecules contain a base paired stem that terminates in the sequence CCA at (A) 3′ Termini (B)5′ Termini (C) Anticodon arm (D) 53 ′′ -Termini

Description : Although each specific tRNA differs from the others in its sequence of nucleotides, all tRNA molecules contain a base paired stem that terminates in the sequence CCA at (A) 3′ Termini (B)5′ Termini (C) Anticodon arm (D) 53 ′′ -Termini

Last Answer : Answer : A

Restriction endonucleases are enzymes which (a) make cuts at specific positions within the DNA molecule (b) recognize a specific nucleotide sequence for binding of DNA ligase (c) restrict the action of the enzyme DNA polymerase (d) remove nucleotides from the ends of the DNA molecule

Description : Restriction endonucleases are enzymes which (a) make cuts at specific positions within the DNA molecule (b) recognize a specific nucleotide sequence for binding of DNA ligase (c) restrict the action of the enzyme DNA polymerase (d) remove nucleotides from the ends of the DNA molecule

Last Answer : (a) make cuts at specific positions within the DNA molecule

The distinctive features of azithromycin include the following except: A. Efficacy against organisms which have developed resistance to erythromycin B. Marked tissue distribution and intracellular penetration C. Long terminal elimination half-life D. Low propensity to drug interactions due to inhibition of cytochrome P450 enzymes

Description : The distinctive features of azithromycin include the following except: A. Efficacy against organisms which have developed resistance to erythromycin B. Marked tissue distribution and intracellular penetration ... D. Low propensity to drug interactions due to inhibition of cytochrome P450 enzymes

Last Answer : A. Efficacy against organisms which have developed resistance to erythromycin

In DNA sequencing, the primer A.specifies where the sequence ends B.specifies where the sequence begins C.both (a) and (b) D.generates variety of different sized fragments

Description : In DNA sequencing, the primer A.specifies where the sequence ends B.specifies where the sequence begins C.both (a) and (b) D.generates variety of different sized fragments

Last Answer : B.specifies where the sequence begins

Actions of adenosine include the following except: A. Depression of A-V node B. Coronary vasodilatation C. Bronchodilatation D. Fall in BP

Description : Actions of adenosine include the following except: A. Depression of A-V node B. Coronary vasodilatation C. Bronchodilatation D. Fall in BP

Last Answer : C. Bronchodilatation

n the DNA molecule, (a) the proportion of adenine in relation to thymine varies with the organism (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → 5′ (c) the total amount of purine nucleotides and pyrimidine nucleotides is not always equal (d) there are two strands which run parallel in the 5′ → 3′ direction.

Description : n the DNA molecule, (a) the proportion of adenine in relation to thymine varies with the organism (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → ... is not always equal (d) there are two strands which run parallel in the 5′ → 3′ direction.

Last Answer : (b) there are two strands which run anti- parallel-one in 5′ → 3′ direction and other in 3′ → 5′

Which of the statements give below is correct with respect to frameshift mutation a) a single nucleotide base change, insertion, or deletion of the genetic material b) Glutamine is replaced by valine c) Sickle cell anemia is an example d) insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.

Description : Which of the statements give below is correct with respect to frameshift mutation a) a single nucleotide base change, insertion, or deletion of the genetic material b) Glutamine is replaced by valine c) ... or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.

Last Answer : d) insertions or deletions of a number of nucleotides in a DNA sequence that is not divisible by three.

Terminal transferase (A) Removes nucleotides from 3’ end (B) Adds nucleotides at 3’ end (C) Removes nucleotides from 3’end (D) Adds nucleotides at 3’end

Description : Terminal transferase (A) Removes nucleotides from 3’ end (B) Adds nucleotides at 3’ end (C) Removes nucleotides from 3’end (D) Adds nucleotides at 3’end

Last Answer : Answer : B

The amino terminal of all polypeptide chain at the time of synthesis in E. coli is tagged to the amino acid residue: (A) Methionine (B) Serine (C) N-formyl methinine(D) N-formal serine

Description : The amino terminal of all polypeptide chain at the time of synthesis in E. coli is tagged to the amino acid residue: (A) Methionine (B) Serine (C) N-formyl methinine(D) N-formal serine

Last Answer : Answer : C

The correct statement concerning RNA and DNA polymerases is (A) RNA polymerase use nucleoside diphosphates (B) RNA polymerase require primers and add bases at 5’ end of the growing polynucleotide chain (C) DNA polymerases can add nucleotides at both ends of the chain (D) All RNA and DNA polymerases can add nucleotides only at the 3’ end of the growing polynucleotide chain

Description : The correct statement concerning RNA and DNA polymerases is (A) RNA polymerase use nucleoside diphosphates (B) RNA polymerase require primers and add bases at 5' end of the growing polynucleotide ... and DNA polymerases can add nucleotides only at the 3' end of the growing polynucleotide chain

Last Answer : Answer : D

The correct sequence of the reactions of catabolism of adenosine to uric acid is (A) Adenosine→hypoxanthine→xanthine→uric acid (B) Adenosine→xanthine→inosine→uric acid (C) Adenosine→inosine→hypoxanthine→ xanthine uric acid (D) Adenosine→xanthine→inosine→hypoxanthine uric acid

Description : The correct sequence of the reactions of catabolism of adenosine to uric acid is (A) Adenosine→hypoxanthine→xanthine→uric acid (B) Adenosine→xanthine→inosine→uric acid (C) Adenosine→inosine→hypoxanthine→ xanthine uric acid (D) Adenosine→xanthine→inosine→hypoxanthine uric acid

Last Answer : Answer : C

All of the following statements about post-transcriptional processing of tRNA are true except (A) Introns of some tRNA precursors are removed (B) CCA is added at 3′ end (C) 7-Methylguanosine triphosphate cap is added at 5′ end (D) Some bases are methylated

Description : All of the following statements about post-transcriptional processing of tRNA are true except (A) Introns of some tRNA precursors are removed (B) CCA is added at 3′ end (C) 7-Methylguanosine triphosphate cap is added at 5′ end (D) Some bases are methylated

Last Answer : Answer : C

I-cell disease results from absence of the following from lysosomal enzymes: (A) Signal sequence (B) Mannose-6-phosphate (C) Sialic acid (D) A serine residue

Description : I-cell disease results from absence of the following from lysosomal enzymes: (A) Signal sequence (B) Mannose-6-phosphate (C) Sialic acid (D) A serine residue

Last Answer : Answer : D

How many 8’s are there in the following sequence which are preceded by 5 but not immediately followed by 3? 5 8 3 7 5 8 6 3 8 5 4 5 8 4 7 6 5 5 8 3 5 8 7 5 8 2 8 5 (A) 4 (B) 5 (C) 7 (D) 3

Description : How many 8’s are there in the following sequence which are preceded by 5 but not immediately followed by 3?  5 8 3 7 5 8 6 3 8 5 4 5 8 4 7 6 5 5 8 3 5 8 7 5 8 2 8 5 (A) 4 (B) 5 (C) 7 (D) 3

Last Answer : Answer: A

A substance which participates readily in both acid-base and oxidation-reduction reactions is:

Description : A substance which participates readily in both acid-base and oxidation-reduction reactions is:

Last Answer : A substance which participates readily in both acid-base and oxidation-reduction reactions is: A. `Na_(2) CO_(3)` B ... KMnO_(4)` D. `H_(2)C_(2)O_(4)`

Cistron is a) The coding sequence of DNA b) The functional unit of DNA molecule that codes for a particular gene product c) Intervening non coding sequence of DNA d) The sequences which are removed during RNA splicing.

Description : Cistron is a) The coding sequence of DNA b) The functional unit of DNA molecule that codes for a particular gene product c) Intervening non coding sequence of DNA d) The sequences which are removed during RNA splicing.

Last Answer : b) The functional unit of DNA molecule that codes for a particular gene product c) Intervening non coding sequence of DNA

All following are naturally occurring nucleotides except (A) Cyclic AMP (B) ATP (C) DNA (D) Inosine monophosphate

Description : All following are naturally occurring nucleotides except (A) Cyclic AMP (B) ATP (C) DNA (D) Inosine monophosphate

Last Answer : Answer : C

All of the following occur in orotic aciduria except (A) Increased synthesis of pyrimidine nucleotides (B) Increased excretion of orotic acid in urine (C) Decreased synthesis of cytidine triphosphate (D) Retardation of growth

Description : All of the following occur in orotic aciduria except (A) Increased synthesis of pyrimidine nucleotides (B) Increased excretion of orotic acid in urine (C) Decreased synthesis of cytidine triphosphate (D) Retardation of growth

Last Answer : Answer : A

All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Dihydro-orotase (D) Dihydro-orotate dehydrogenase

Description : All the enzymes required for de novo synthesis of pyrimidine nucleotides are cytosolic except (A) Carbamoyl phosphate synthetase (B) Aspartate transcarbamoylase (C) Dihydro-orotase (D) Dihydro-orotate dehydrogenase

Last Answer : Answer : D

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequenceof a gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... sequenceof a gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequence of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction fragment length polymorphism (RFLP) is usually formed in coding sequence of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Description : Which of the following statement is correct? A- The size and sequence of introns can be deduced from the cDNA sequence B- .Restriction endonuclease can cleave ss and dsDNA both C- Restriction ... of a Gene D- Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

Last Answer : Amino acid sequence of a protein can be deduced from corresponding cDNA nucleotide

The proteins destined to be transported out of the cell have all the following features except (A) They possess a signal sequence (B) Ribosomes synthesizing them are bound to endoplasmic reticulum (C) After synthesis, they are delivered into Golgi apparatus (D) They are tagged with ubiquitin

Description : The proteins destined to be transported out of the cell have all the following features except (A) They possess a signal sequence (B) Ribosomes synthesizing them are bound to endoplasmic reticulum (C) After synthesis, they are delivered into Golgi apparatus (D) They are tagged with ubiquitin

Last Answer : Answer : D

Intestinal nucleosidases act on nucleosides and produce (A) Purine base only (B) Phosphate only (C) Sugar only (D) Purine or pyrimidine bases and sugars

Description : Intestinal nucleosidases act on nucleosides and produce (A) Purine base only (B) Phosphate only (C) Sugar only (D) Purine or pyrimidine bases and sugars

Last Answer : Answer : D

A nucleotide consists of (A) A nitrogenous base like choline (B) Purine + pyrimidine base + sugar + phosphorous (C) Purine or pyrimidine base + sugar (D) Purine or pyrimidine base + phosphorous

Description : A nucleotide consists of (A) A nitrogenous base like choline (B) Purine + pyrimidine base + sugar + phosphorous (C) Purine or pyrimidine base + sugar (D) Purine or pyrimidine base + phosphorous

Last Answer : Answer : B

A nucleoside consists of (A) Nitrogenous base (B) Purine or pyrimidine base + sugar (C) Purine or pyrimidine base + phosphorous (D) Purine + pyrimidine base + sugar + phosphorous

Description : A nucleoside consists of (A) Nitrogenous base (B) Purine or pyrimidine base + sugar (C) Purine or pyrimidine base + phosphorous (D) Purine + pyrimidine base + sugar + phosphorous

Last Answer : Answer : B

Thiamine is (A) Water-soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Description : Thiamine is (A) Water-soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Last Answer : Answer : D

Thymine is (A) Water soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Description : Thymine is (A) Water soluble vitamin (B) Fat soluble vitamin (C) Purine base (D) Pyrimidine base

Last Answer : Answer : D

Folic acid or folate consists of the (A) Base pteridine, p-amino benzoic acid and asparate (B) Base purine, p-amino benzoic acid and glutamate (C) Base pteridine, p-amino benzoic acid and glutamate (D) Base purine, p-hydroxy benzoic acid and glutamate

Description : Folic acid or folate consists of the (A) Base pteridine, p-amino benzoic acid and asparate (B) Base purine, p-amino benzoic acid and glutamate (C) Base pteridine, p-amino benzoic acid and glutamate (D) Base purine, p-hydroxy benzoic acid and glutamate

Last Answer : Answer : C