Description : The actions of platelet activating factor include the following except: A. Increased capillary permeability B. Bronchodilatation C. Vasodilatation D. Erosion of gastric mucosa
Last Answer : B. Bronchodilatation
Description : Actions of bradykinin include the following except: A. Fall in blood pressure B. Cardiac depression C. Increase in capillary permeability D. Bronchoconstriction
Last Answer : B. Cardiac depression
Description : Morphine affords symptomatic relief of dyspnoea in acute left ventricular failure by the following mechanisms except: A. Bronchodilatation B. Depression of respiratory centre C. Reduction in cardiac preload D. Shift of blood from pulmonary to systemic circuit
Last Answer : A. Bronchodilatation
Description : Advantages of selective serotonin reuptake inhibitors (SSRIs) include the following except: A. No interference with ejaculation and orgasm B. Minimal sedative action C. Unlikely to cause fall in BP D. Lack of seizure precipitating potential
Last Answer : A. No interference with ejaculation and orgasm
Description : Actions of thyroxine include the following except: A. Induction of negative nitrogen balance B. Reduction in plasma cholesterol level C. Fall in plasma free fatty acid level D. Rise in blood sugar leve
Last Answer : C. Fall in plasma free fatty acid level
Description : 17.5 Actions of thyroxine include the following except: A. Induction of negative nitrogen balance B. Reduction in plasma cholesterol level C. Fall in plasma free fatty acid level D. Rise in blood sugar level
Last Answer : D. Rise in blood sugar level
Description : The principles of antihypertensive drug usage enunciated in JNC VI and WHO-ISH guidelines include the following except: A. Therapy for grade I and II hypertension should be initiated with a single drug ... initially fails to lower BP, it should be replaced by a drug/combination from another class
Last Answer : C. All subjects with BP higher than 140/90 mmHg should be put on antihypertensive medication immediately
Description : Potentiation of bradykinin appears to play a role in the following effects of angiotensin converting enzyme inhibitors except: A. Fall in BP in the short term B. Fall in BP in the long term C. Cough in susceptible individuals D. Angioedema in susceptible individuals
Last Answer : B. Fall in BP in the long term
Description : The following action of digoxin is responsible for beneficial effect in auricular fibrillation: A. Increased myocardial contractility B. Suppression of SA node C. Depression of A-V conduction D. Enhanced Purkinje fibre automaticity
Last Answer : C. Depression of A-V conduction
Description : All of the following contribute to the antihypertensive action of propranolol except: A. Direct vasodilatation B. Decreased renin release from kidney C. Adaptation of blood vessels to reduced cardiac output D. Less noradrenaline release from sympathetic nerve endings
Last Answer : A. Direct vasodilatation
Description : Actions of angiotensin II include: a. increases the release of aldosterone b. reduces renin release from the kidney c. vasodilatation d. promotes microalbuminuria
Last Answer : promotes microalbuminuria
Description : Theophylline is believed to benefit asthma patients by exerting the following actions except: A. Bronchodilatation B. Augmentation of diaphragmatic contractility C. Reduced mediator release D. Inhibition of antigen: antibody reaction
Last Answer : D. Inhibition of antigen: antibody reaction
Description : Regular low-to-moderate alcohol consumption is associated with: A. Lower incidence of coronary artery disease B. Myocardial depression C. Physical dependence D. Wernicke's encephalopathy
Last Answer : A. Lower incidence of coronary artery disease
Description : Actions of morphine include the following except: A. Vagal stimulation B. Miosis C. Antiemetic D. Postural hypotensio
Last Answer : C. Antiemetic
Description : Actions of chlorpromazine include the following except: A. Indifference to external stimuli B. Postural hypotension C. Hypoprolactinemia D. Hypothermia in cold surroundings
Last Answer : C. Hypoprolactinemia
Description : Actions of oxytocin include the following except: A. Vasoconstriction B. Increased water reabsorption in renal collecting ducts C. Contraction of mammary myoepithelium D. Release of prostaglandins from endometrium
Last Answer : A. Vasoconstriction
Description : Actions of progesterone include the following except: A. Rise in body temperature B. Endometrial proliferation C. Proliferation of acini in mammary gland D. Suppression of cell mediated immunity
Last Answer : B. Endometrial proliferatio
Description : 16.3 Actions of growth hormone include the following except: A. Increased protein synthesis B. Increased fat utilization C. Increased carbohydrate utilization D. Glucose intolerance
Last Answer : C. Increased carbohydrate utilization
Description : At therapeutic doses, actions of amphetamine include the following except: A. Prolongation of attention span B. Wakefulness C. Lowering of seizure threshold D. Delaying fatigue
Last Answer : C. Lowering of seizure threshold
Description : The metabolic actions of adrenaline include the following except: A. Glycogenolysis in liver and muscle B. Inhibition of neoglucogenesis in liver C. Lipolysis in adipose tissue D. Release of potassium from liver followed by its uptake
Last Answer : B. Inhibition of neoglucogenesis in liver
Description : Features of µ (Mu) opioid receptor include the following except: A. Acts by inhibiting cAMP formation B. Mediates miotic action C. Mediates low ceiling respiratory depression D. Mediates high ceiling supraspinal analgesia
Last Answer : C. Mediates low ceiling respiratory depression
Description : Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients ... 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil
Last Answer : A. It does not produce any side effect
Description : Morphine induced fall in blood pressure involves the following factors except: A. Direct cardiac depression B. Direct reduction of vascular tone C. Vasomotor centre depression D. Histamine release
Last Answer : A. Direct cardiac depression
Description : Use of sublingual/oral nifedipine soft geletine capsule for rapid BP lowering in hypertensive urgency has been discarded because of: A. Delayed onset of action B. Inability to control the rate and extent of fall in BP C. Reports of adverse/fatal outcome D. Both 'B' and 'C'
Last Answer : D. Both 'B' and 'C'
Description : Select the nonapeptide which can be generated from plasma globulin by snake venom enzymes, causes fall in BP and intense pain when applied to blister base: A. Kallidin B. Bradykinin C. Angiotensin II D. Angiotensin III
Last Answer : B. Bradykinin
Description : Bradykinin and angiotensin II have the following feature common to both: A. They both cause fall in BP B. They both are degraded by Kininase II C. Their precursor proteins are plasma α2 globulins D. They both release aldosterone from adrenal cortex
Last Answer : C. Their precursor proteins are plasma α2 globulins
Description : The following local anaesthetic raises BP instead of tending to cause a fall: A. Cocaine B. Dibucaine C. Lignocaine D. Procaine
Last Answer : A. Cocaine
Description : Phentolamine test is considered positive for pheochromocytoma if there is a: A. Rise in BP by more than 35 mm Hg systolic and 25 mm Hg diastolic B. Rise in systolic but fall in diastolic BP C. Fall in both ... 20 mm Hg D. Fall in BP by more than 35 mm Hg systolic and more than 25 mm Hg diastolic
Last Answer : D. Fall in BP by more than 35 mm Hg systolic and more than 25 mm Hg diastolic
Description : The typical response to intravenous injection of 5-HT in an anaesthetised animal is: A. Rise in BP B. Fall in BP C. Rise followed by brief fall in BP D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Last Answer : D. Transient fall, followed by brief rise, followed by prolonged fall in BP
Description : Ticlopidine is recommended for the following except: A. To reduce neurological sequelae of stroke B. Transient ischaemic attacks C. To prevent occlusion of coronary artery bypass graft D. Intermittent claudication
Last Answer : A. To reduce neurological sequelae of stroke
Description : 5-HT appears to play a role in the following except: A. Regulation of normal BP B. Regulation of intestinal peristalsis C. Haemostasis D. Causation of migraine
Last Answer : A. Regulation of normal BP
Description : Pancuronium differs from tubocurarine in that: A. It is a depolarizing blocker B. Its action is not reversed by neostigmine C. It can cause rise in BP on rapid I.V. injection D. It causes marked histamine release
Last Answer : C. It can cause rise in BP on rapid I.V. injection
Description : Digitalis slows the heart in congestive heart failure by: A. Increasing vagal tone B. Decreasing sympathetic overactivity C. Direct depression of sinoatrial node D. All of the above
Last Answer : D. All of the above
Description : Intravenous furosemide promptly mitigates dyspnoea in acute left ventricular failure by: A. Producing bronchodilatation B. Causing rapid diuresis and reducing circulating blood volume C. Increasing venous capacitance and reducing cardiac preload. D. Stimulating left ventricular contractility
Last Answer : C. Increasing venous capacitance and reducing cardiac preload.
Description : Choose the correct statement(s) about ipratropium bromide: A. It preferentially dilates peripheral bronchioles B. It produces additional bronchodilatation when added to nebulized salbutamol C. As metered dose inhaler it is used for terminating asthma attacks D. Both 'B' and 'C'
Last Answer : B. It produces additional bronchodilatation when added to nebulized salbutamol
Description : Propranolol does not block the following action of adrenaline: A. Bronchodilatation B. Lipolysis C. Muscle tremor D. Mydriasis
Last Answer : D. Mydriasis
Description : What is true of nicotinic acid as well as nicotinamide: A. Both possess vitamin B3 activity B. Both cause cutaneous vasodilatation C. Both lower plasma triglyceride and VLDL levels D. Both cause hyperglycaemia after prolonged medication
Last Answer : A. Both possess vitamin B3 activity
Description : The antidotal effect of sodium nitrite in cyanide poisoning is dependent upon: A. Chemical combination of sodium nitrite with cyanide B. Vasodilatation caused by sodium nitrite C. ... haemoglobin to methaemoglobin by sodium nitrite D. Facilitation of cyanocobalamine formation by sodium nitrite
Last Answer : C. Conversion of haemoglobin to methaemoglobin by sodium nitrite
Description : The following kinin action is mediated primarily by the kinin B1 receptor: A. Intestinal contraction B. Bronchoconstriction C. EDRF release and vasodilatation D. Production of Interleukin, TNFα and other inflammatory mediators
Last Answer : . Production of Interleukin, TNFα and other inflammatory mediators
Description : Actions of prostaglandin E2 include the following except: A. Fall in blood pressure B. Bronchoconstriction C. Uterine contraction D. Inhibition of gastric acid secretion
Last Answer : B. Bronchoconstriction
Description : The common features of introns include all the following except (A) The base sequence begins with GU (B) The base sequence ends with AG (C) The terminal AG sequence is preceded by a purine rich tract of ten nucleotides (D) An adenosine residue in branch site participates in splicing
Last Answer : Answer : C
Description : Digitalis induced increase in refractory period of myocardial fibres is most consistent and pronounced in the: A. Atria B. Ventricles C. A-V node D. Purkinje fibres
Last Answer : C. A-V node
Description : Symptoms of circulatory systemic overload during excessive IV fluids include all except A) Oliguria B) Increased BP C) Anxiety D) Pulmonary edema
Last Answer : Ans: A
Description : Metoclopramide has the following actions except: A. Increases lower esophageal sphincter tone B. Increases tone of pyloric sphincter C. Increases gastric peristalsis D. Increases intestinal peristalsis
Last Answer : B. Increases tone of pyloric sphincter
Description : Imipramine produces the following actions except: A. Euphoria B. Dryness of mouth C. Tachycardia D. Lowering of seizure threshold
Last Answer : A. Euphoria