Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride

Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride
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An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C) A low blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Description : An inherited or acquired renal tubular defect in the reabsorption of phosphate (Vit D resistant ricket) is characterized with (A) Normal serum Phosphate (B) High serum phosphate (C ... blood phosphorous with elevated alkaline Phosphate (D) A high blood phosphorous with decreased alkaline phosphatase

Last Answer : Answer : C

The most important effect of aldosterone is to (A) Increase the rate of tubular reabsorption of sodium (B) Decrease the rate of tubular reabsorption of potassium (C) Decrease the reabsorption of chloride (D) Decrease the renal reabsorption of sodium

Description : The most important effect of aldosterone is to (A) Increase the rate of tubular reabsorption of sodium (B) Decrease the rate of tubular reabsorption of potassium (C) Decrease the reabsorption of chloride (D) Decrease the renal reabsorption of sodium

Last Answer : Answer : A

An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Description : An important finding in glycinuria is (A) Excess excretion of oxalate in the urine (B) Deficiency of enzyme glycinase (C) Significantly increased serum glycine level (D) Defect in renal tubular reabsorption of glycine

Last Answer : Answer : D

Mineralocorticoids increase the tubular reabsorption of (A) Sodium and calcium (B) Sodium and potassium (C) Sodium and chloride (D) Potassium and chloride 224 MCQs IN BIOCHEMISTRY

Description : Mineralocorticoids increase the tubular reabsorption of (A) Sodium and calcium (B) Sodium and potassium (C) Sodium and chloride (D) Potassium and chloride 224 MCQs IN BIOCHEMISTRY

Last Answer : Answer : C

Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis

Description : Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis

Last Answer : Answer : A

Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Description : Para-amino hippurate excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal plasma flow

Last Answer : Answer : D

Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Description : Phenolsulphonephthalein excretion test is an indicator of (A) Glomerular filtration (B) Tubular secretion (C) Tubular reabsorption (D) Renal blood low

Last Answer : Answer : D

Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Description : Inulin clearance is a measure of (A) Glomerular filtration rate (B) Tubular secretion flow (C) Tubular reabsorption rate (D) Renal plasma flow

Last Answer : Answer : B

Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells

Description : Renal glycosuria occurs due to (A) Increased filtration of glucose in glomeruli (B) Increased secretion of glucose by renal tubular cells (C) Decreased reabsorption of glucose by renal tubular cells (D) Increased conversion of glycogen into glucose in tubular cells

Last Answer : Answer : D

PTH causes all of the following except (A) Increased intestinal absorption of calcium (B) Increased intestinal absorption of phosphate (C) Increased tubular reabsorption of calcium (D) Increased tubular reabsorption of phosphate

Description : PTH causes all of the following except (A) Increased intestinal absorption of calcium (B) Increased intestinal absorption of phosphate (C) Increased tubular reabsorption of calcium (D) Increased tubular reabsorption of phosphate

Last Answer : Answer : D

Tubular reabsorption of calcium is increased by (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Calcitriol (D) All of these

Description : Tubular reabsorption of calcium is increased by (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Calcitriol (D) All of these

Last Answer : Answer : C

All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased

Description : All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased

Last Answer : Answer : D

The maximal renal tubular reabsorptive capacity for calcium (Tmca) in mg/min is about (A) 1.5 ± 0.1 (B) 4.99 ± 0.21 (C) 5.5 ± 1.2 (D) 10.2 ± 2.2

Description : The maximal renal tubular reabsorptive capacity for calcium (Tmca) in mg/min is about (A) 1.5 ± 0.1 (B) 4.99 ± 0.21 (C) 5.5 ± 1.2 (D) 10.2 ± 2.2

Last Answer : Answer : B

The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure

Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure

Last Answer : Answer : A

Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in an autosomal dominant manner 4) can be reduced with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure

Description : Which of the following is associated with Hyperuricaemia? 1) is usually due to an excess purine consumption 2) occurs in association with acute lymphoblastic leukaemia 3) in primary gout is inherited in ... with low dose aspirin therapy 5) can be treated with uricosuric drugs even in renal failure

Last Answer : Answers-2 Hyperuricaemia may be due to increased purine intake, urate production or reduced urate clearance, and is most commonly due to the latter. Therefore it can occur in association with enhanced ... . Many of the uricosuric drugs may be detrimental in renal failure and may not be effective.

Furosemide inhibits reabsorption of sodium and chloride in (A) Proximal convoluted tubules (B) Loop of Henle (C) Distal convoluted tubules (D) Collecting ducts

Description : Furosemide inhibits reabsorption of sodium and chloride in (A) Proximal convoluted tubules (B) Loop of Henle (C) Distal convoluted tubules (D) Collecting ducts

Last Answer : Answer : B

Mineralocorticoids increase the tubular secretion of (A) Sodium (B) Potassium (C) Chloride (D) Bicarbonate

Description : Mineralocorticoids increase the tubular secretion of (A) Sodium (B) Potassium (C) Chloride (D) Bicarbonate

Last Answer : Answer : B

The following are true about aldosterone: a. it is secreted by the adrenal medulla b. its secretion is stimulated by decreased blood volume c. it stimulates active reabsorption of sodium in the distal renal tubules. d. it causes increased secretion of potassium by the distal renal tubules.

Description : The following are true about aldosterone: a. it is secreted by the adrenal medulla b. its secretion is stimulated by decreased blood volume c. it stimulates active reabsorption of sodium in the distal renal tubules. d. it causes increased secretion of potassium by the distal renal tubules.

Last Answer : it causes increased secretion of potassium by the distal renal tubules.

Obligatory reabsorption of water (A) Is about 50% of the total tubular reabsorption of water (B) Is increased by antidiuretic hormone (C) Occurs in distal convoluted tubules (D) Is secondary to reabsorption of solutes

Description : Obligatory reabsorption of water (A) Is about 50% of the total tubular reabsorption of water (B) Is increased by antidiuretic hormone (C) Occurs in distal convoluted tubules (D) Is secondary to reabsorption of solutes

Last Answer : Answer : D

Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose

Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose

Last Answer : Answer : C

Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension or circulatolry collapse (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia

Description : Acute renal failure (ARF) may be caused by all of the following except (a) Acute tubular necrosis (ATN) due to drug therapy (e.g., aminoglycosides, contrast media) (b) Severe hypotension ... (c) Decreased cardiac output, as from congestive heart failure (d) Hemolysis, myoglobinuria (e) Hyperkalemia

Last Answer : Ans: E

Anion gap is increased in (A) Renal tubular acidosis (B) Metabolic acidosis resulting from diarrhoea (C) Metabolic acidosis resulting from intestinal obstruction (D) Diabetic ketoacidosis

Description : Anion gap is increased in (A) Renal tubular acidosis (B) Metabolic acidosis resulting from diarrhoea (C) Metabolic acidosis resulting from intestinal obstruction (D) Diabetic ketoacidosis

Last Answer : Answer : B

Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells

Description : Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells

Last Answer : Answer : D

Target tissue of insulin is (A) Red blood cells (B) Renal tubular cells (C) GI tract epithelial cells (D) Liver

Description : Target tissue of insulin is (A) Red blood cells (B) Renal tubular cells (C) GI tract epithelial cells (D) Liver

Last Answer : Answer : D

The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate

Description : The Tm for PAH i.e the maximal secretory capacity of the tubule for PAH can be used to gavge the (A) Extent of tubular damage FATS AND FATTY ACID METABOLISM 81 (B) Impairment of the capacity of the tubule to perform osmotic work (C) Impairment of renal plasma flow (D) Glomerular filtration rate

Last Answer : Answer : A

Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Description : Creatinine EDTA clearance is a test to measure (A) Renal plasma flow (B) Filtration fraction (C) Glomerular filtration rate (D) Tubular function

Last Answer : Answer : C

Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Description : Measurement of insulin clearance test is a measure of (A) Glomerular filtration rate (B) Filtration factor (C) Renal plasma flow (D) Tubular secretory mass

Last Answer : Answer : A

Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Description : Urea clearance test is used to determine the (A) Glomerular filtration rate (B) Renal plasma flow (C) Ability of kidney to concentrate the urine (D) Measurement of tubular mass

Last Answer : Answer : A

An early feature of renal disease is (A) Impairment of the capacity of the tubule to perform osmotic work (B) Decrease in maximal tubular excretory capacity (C) Decrease in filtration factor (D) Decrease in renal plasma flow

Description : An early feature of renal disease is (A) Impairment of the capacity of the tubule to perform osmotic work (B) Decrease in maximal tubular excretory capacity (C) Decrease in filtration factor (D) Decrease in renal plasma flow

Last Answer : A

Which of the following may be responsible for a hypokalaemic hypertension 1) Non-classical congenital adrenal hyperplasia 2) Barter's syndrome 3) Diabetic nephropathy 4) Liddle's syndrome 5) Type IV renal tubular acidosis

Description : Which of the following may be responsible for a hypokalaemic hypertension 1) Non-classical congenital adrenal hyperplasia 2) Barter's syndrome 3) Diabetic nephropathy 4) Liddle's syndrome 5) Type IV renal tubular acidosis

Last Answer : Answers-4 Liddle's syndrome is typically asscoiated with hypokalaemic hypertension and low renin and aldosterone concentrations - the so called pseudo-hyperaldosteronism. Barter's syndrome is associated ... , which may also be produced with diabetic nephropathy. Hence hyperkalaemia is more typical.

Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ammonium 4) is lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting

Description : Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ... lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting

Last Answer : Answers-2 c - excretion of ammonium occurs when an acid urine is produced but the pH of urine is of course determined by the concentration of H+ ions d-unable to lower the pH to ... and distal nephron and this perpetuates the metabolic alkalosis until the fluid balance is restored with IV fluids.

During dehydration what is the substance that is usually lost by the body? (1) Sugar (2) Sodium chloride (3) Calcium phosphate (4) Potassium chloride

Description : During dehydration what is the substance that is usually lost by the body? (1) Sugar (2) Sodium chloride (3) Calcium phosphate (4) Potassium chloride

Last Answer : (2) Sodium chloride Explanation: Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the formula NaC1, representing equal proportions of sodium and ... . It is used as a carrier for other ingredients, dehydrating agent, enzyme inhibitor and tenderizer.

During dehydration what is the substance that is usually lost by the body ? (1) Sugar (2) Sodium chloride (3) Calcium phosphate (4) Potassium chloride

Description : During dehydration what is the substance that is usually lost by the body ? (1) Sugar (2) Sodium chloride (3) Calcium phosphate (4) Potassium chloride

Last Answer : Sodium chloride

Thiazide diuretics enhance K+ elimination in urine primarily by: A. Inhibiting proximal tubular K+ reabsorption B. Inhibiting Na+ K+-2Cl– cotransport in the ascending limb of loop of Henle C. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K+ D. Potentiating the action of aldosterone

Description : Thiazide diuretics enhance K+ elimination in urine primarily by: A. Inhibiting proximal tubular K+ reabsorption B. Inhibiting Na+ K+-2Cl- cotransport in the ascending limb of loop of Henle C ... in the distal tubular fluid to exchange with interstitial K+ D. Potentiating the action of aldosterone

Last Answer : C. Increasing the availability of Na+ in the distal tubular fluid to exchange with interstitial K

In studies of the human body, which of the following terms is used to describe the first step in the production of urine? Is it: a) tubular secretion b) tubular reabsorption c) glomerular filtration d) none of these

Description : In studies of the human body, which of the following terms is used to describe the first step in the production of urine? Is it: a) tubular secretion b) tubular reabsorption c) glomerular filtration d) none of these

Last Answer : ANSWER: C -- GLOMERULAR FILTRATION

Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury

Description : Impaired galactose tolerance test suggests (A) Defect in glucose utilisation (B) Liver cell injury (C) Renal defect (D) Muscle injury

Last Answer : Answer : B

Serum inorganic phosphorous decreases in all the following conditions except (A) Hyperparathyroidism (B) Intestinal malabsorption (C) Osteomalacia (D) Chronic renal failure

Description : Serum inorganic phosphorous decreases in all the following conditions except (A) Hyperparathyroidism (B) Intestinal malabsorption (C) Osteomalacia (D) Chronic renal failure

Last Answer : Answer : D

Serum inorganic phosphorous rises in all the following conditions except (A) Hypoparathyroidism (B) Hypervitaminosis D (C) Chronic renal failure (D) After a carbohydrate-rich meal MINERAL METABOLISM 197

Description : Serum inorganic phosphorous rises in all the following conditions except (A) Hypoparathyroidism (B) Hypervitaminosis D (C) Chronic renal failure (D) After a carbohydrate-rich meal MINERAL METABOLISM 197

Last Answer : Answer : D

Ricket is caused due to the deficiency of which vitamin?

Description : Ricket is caused due to the deficiency of which vitamin?

Last Answer : Vitamin-D

The three elements most needed in common fertilisers are : (1) Sulphur, Phosphorous and Sodium (2) Nitrogen, Potassium and Phosphorous (3) Phosphorous, Sodium and Nitrogen (4) Calcium, Phosphorous and Potassium

Description : The three elements most needed in common fertilisers are : (1) Sulphur, Phosphorous and Sodium (2) Nitrogen, Potassium and Phosphorous (3) Phosphorous, Sodium and Nitrogen (4) Calcium, Phosphorous and Potassium

Last Answer : Nitrogen, Potassium and Phosphorous

Mineralcorticoids regulate the metabolism of all of the following except (A) Sodium (B) Potassium (C) Calcium (D) Chloride

Description : Mineralcorticoids regulate the metabolism of all of the following except (A) Sodium (B) Potassium (C) Calcium (D) Chloride

Last Answer : Answer : C

Vasopressin (ADH) (A) Enhance facultative reabsorption of water (B) Decreases reabsorption of water (C) Increases excretion of calcium (D) Decreases excretion of calcium

Description : Vasopressin (ADH) (A) Enhance facultative reabsorption of water (B) Decreases reabsorption of water (C) Increases excretion of calcium (D) Decreases excretion of calcium

Last Answer : Answer : A

In ricket, the product of Ca x p (in mg/ 100 ml) in serum is below (A) 30 (B) 50 (C) 70 (D) 100

Description : In ricket, the product of Ca x p (in mg/ 100 ml) in serum is below (A) 30 (B) 50 (C) 70 (D) 100

Last Answer : Answer : A

A deficiency of vitamin B12 causes (A) Beri-Beri (B) Scurvy (C) Perniciuos anemia (D) Ricket

Description : A deficiency of vitamin B12 causes (A) Beri-Beri (B) Scurvy (C) Perniciuos anemia (D) Ricket

Last Answer : Answer : C

The Vitamin B1 deficiency causes (A) Ricket (B) Nyctalopia (C) Beriberi (D) Pellagra

Description : The Vitamin B1 deficiency causes (A) Ricket (B) Nyctalopia (C) Beriberi (D) Pellagra

Last Answer : Answer : C

Deficiency of vitamin D causes (A) Ricket and osteomalacia (B) Tuberculosis of bone (C) Hypthyroidism (D) Skin cancer

Description : Deficiency of vitamin D causes (A) Ricket and osteomalacia (B) Tuberculosis of bone (C) Hypthyroidism (D) Skin cancer

Last Answer : Answer : A

Which of the following would help in prevention of diuresis? (a) More water reabsorption due to undersecretion of ADH. (b) Reabsorption of Na+ and water from renal tubules due to aldosterone. (c) Atrial natriuretic factor causes vasoconstriction. (d) Decrease in secretion of renin by JG cells. (NEE

Description : Which of the following would help in prevention of diuresis? (a) More water reabsorption due to undersecretion of ADH. (b) Reabsorption of Na+ and water from renal tubules due to ... Atrial natriuretic factor causes vasoconstriction. (d) Decrease in secretion of renin by JG cells. (NEE

Last Answer : (b) Reabsorption of Na+ and water from renal tubules due to aldosterone.

Which one of the following correctly explains the function of a specific part of the human nephron? (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the Bowman’s capsule (b) Henle’s loop : most reabsorption of the major substances from the glomerular filtrate (c) Distal convoluted tubule : reabsorption of K+ ions into the surrounding blood capillaries (d) Afferent arteriole : carries the blood away from the glomerulus towards renal vein.

Description : Which one of the following correctly explains the function of a specific part of the human nephron? (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the ... blood capillaries (d) Afferent arteriole : carries the blood away from the glomerulus towards renal vein.

Last Answer : (a) Podocytes : create minute spaces (slit pores) for the filtration of blood into the Bowman’s capsule

The following is true of mannitol except: A. It inhibits solute reabsorption in the thick ascending limb of loop of Henle B. It is contraindicated in patients with increased intracranial tension C. It is contraindicated in acute left ventricular failure D. It is not used to treat cardiac or hepatic or renal edema

Description : The following is true of mannitol except: A. It inhibits solute reabsorption in the thick ascending limb of loop of Henle B. It is contraindicated in patients with increased intracranial tension C. It ... acute left ventricular failure D. It is not used to treat cardiac or hepatic or renal edema

Last Answer : B. It is contraindicated in patients with increased intracranial tension

Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above

Description : Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by: A. Inducing synthesis of Na+K+ATPase B. Inducing synthesis of amiloride sensitive Na+ channels C. Translocating Na+ channels from cytosolic site to luminal membrane D. All of the above

Last Answer : D. All of the above