Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ammonium 4) is lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting

Which of the following concerning the pH of urine is correct? 1) is a useful indicator of the acid/base balance of the blood 2) rises on a vegetarian diet 3) is determined by the concentration of ammonium 4) is lower than 5.5 in renal tubular acidosis 5) would be above 7.0 after prolonged and severe vomiting
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Answers-2 c - excretion of ammonium occurs when an acid urine is produced but the pH of urine is of course determined by the concentration of H+ ions d-unable to lower the pH to less than 5.5 in RTA e- This would be expected in an attempt to compensate for the loss of acid however when there is extracellular fluid depletion the retention of sodium takes priority. Instead of bicarbonate being excreted it is reabsorbed in the proximal and distal nephron and this perpetuates the metabolic alkalosis until the fluid balance is restored with IV fluids.
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A young child presents with respiratory distress, worsening over 2 days. Blood gases show a pH of 7.25, a PCO2 of 7.5kPa, a PO2 of 8.5kPa, and a base excess of -4. Which of the following interpretations is correct? 1) Results are consistent with bronchopulmonary dysplasia. 2) Blood gases suggest type 1 respiratory failure. 3) Immediate intubation is required. 4) Results are consistent with late severe asthma. 5) Bicarbonate may be necessary to correct the acidosis.

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All the following statements about renal tubular acidosis are correct except (A) Renal tubules may be unable to reabsorb bicarbonate (B) Renal tubules may be unable to secrete hydrogen ions (C) Plasma chloride is elevated (D) Anion gap is decreased

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Which of the following may be responsible for a hypokalaemic hypertension 1) Non-classical congenital adrenal hyperplasia 2) Barter's syndrome 3) Diabetic nephropathy 4) Liddle's syndrome 5) Type IV renal tubular acidosis

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Anion gap is increased in (A) Renal tubular acidosis (B) Metabolic acidosis resulting from diarrhoea (C) Metabolic acidosis resulting from intestinal obstruction (D) Diabetic ketoacidosis

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Which of the following is true concerning a 68 year old male with type 2 diabetes diagnosed with type IV renal tubal acidosis? 1) Aminoaciduria would be expected. 2) Fludrocortisone treatment is effective 3) Increased Glomerular filtration rate is expected. 4) Increased urinary bicarbonate would be expected. 5) Normal renal handling of K+ and H+

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Metabolic alkalosis can occur in (A) Severe diarrhoea (B) Renal failure (C) Recurrent vomiting (D) Excessive use of carbonic anhydrase inhibitors

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Tubular secretion helps to maintain a proper acid-base balance by removing one of the following from blood

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Description : Tubular secretion helps to maintain a proper acid-base balance by removing one of the following from blood

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he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect C. It can inhibit insulin release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori

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Which one of the following statements concerning glutamine is correct? (A) Contains three tetratable groups (B) Is classified as an acidic amino acid (C) Contains an amide group (D) Migrates to the cathode during electrophoresis at pH 7.0

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All the following changes in blood chemistry can occur in severe diarrhoea except (A) Decreased pH (B) Decreased bicarbonate (C) Increased pCO2 (D) Increased chloride WATER AND ELECTROLYTE BALANCE 287

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Target tissue of insulin is (A) Red blood cells (B) Renal tubular cells (C) GI tract epithelial cells (D) Liver

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A 59-year-old trauma patient has suffered multiple septic complications including severe pneumonia, intraabdominal abscess, and major wound infection. He has now developed signs of multisystem organ failure. Which of the following statement(s) is/are true concerning necessary changes to be made in his nutritional management? a. Carbohydrate load should be reduced in the face of respiratory failure b. In patients with renal failure, protein intake should be diminished c. During hemodialysis protein intake should be limited to the same extent d. In patients with hepatic failure, carbohydrate load should be increased

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Which of the following statements are true of a patient with hyperglycemia and hyponatremia? A. The sodium concentration must be corrected by 5 mEq. per 100 mg. per 100 ml. elevation in blood glucose. B. With normal renal function, this patient is likely to be volume overloaded. C. Proper fluid therapy would be unlikely to include potassium administration. D. Insulin administration will increase the potassium content of cells. E. Early in treatment adequate urine output is a reliable measure of adequate volume resuscitation.

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The maximal renal tubular reabsorptive capacity for calcium (Tmca) in mg/min is about (A) 1.5 ± 0.1 (B) 4.99 ± 0.21 (C) 5.5 ± 1.2 (D) 10.2 ± 2.2

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All the following features are found in blood chemistry in uncompensated lactic acidosis except (A) pH is decreased (B) Bicarbonate is decreased (C) pCO2 is normal (D) Anion gap is normal

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If a drug is excreted in urine at the rate of 10 mg/hr at a steady-state plasma concentration of 5 mg/L, then its renal clearance is: A. 0.5 L/hr B. 2.0 L/hr C. 5.0 L/hr D. 20 L/hr

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If a drug is excreted in urine at the rate of 10 mg/hr at a steady-state plasma concentration of 5 mg/L, then its renal clearance is: A. 0.5 L/hr B. 2.0 L/hr C. 5.0 L/hr D. 20 L/hr

Description : If a drug is excreted in urine at the rate of 10 mg/hr at a steady-state plasma concentration of 5 mg/L, then its renal clearance is: A. 0.5 L/hr B. 2.0 L/hr C. 5.0 L/hr D. 20 L/hr

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During deficiency of thiamine the concentration of the following compound rises in blood and intracellular fluid: (A) Glycogen (B) Sugar (C) Amino acids (D) Pyruvic acid

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Description : In severe acidosis, the output of urea is (A) Decreased (B) Slightly increased (C) Highly increased (D) Moderately increased

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Inborn errors of urea cycle can cause all the following except (A) Vomiting (B) Ataxia (C) Renal failure (D) Mental retardation

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Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride

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Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells

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Last Answer : Answer : A

Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis

Description : Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis

Last Answer : Answer : A