Pharmaceutical medicines are usually a doctor's first choice to treat ulcerative colitis. They are effective at controlling inflammation of the intestines while promoting the healing of damaged tissues. Some drugs can even promote remission of the disease. Particular treatments vary by severity of the disorder in a particular person.Mild to moderate ulcerative colitisMild to moderate ulcerative colitis is effectively managed with aminosalicylates, such as sulfasalazine or mesalamine. They relieve inflammation with few side effects. For those with mild conditions, the disorder often goes into remission and stays inactive. If symptoms continue past the first few weeks of treatment, corticosteroids are used in combination with aminosalicylates. These stronger drugs provide even more relief from inflammation, but are not recommended for long periods of use.Mild to moderate ulcerative colitis is effectively managed with a class of drugs called aminosalicylates that work to relieve intestinal inflammation and produce the least amount of side effects. Severe ulcerative colitisWhen aminosalicylates are not strong enough, other drugs and combinations are used to treat the most severe forms of ulcerative colitis. Since inflammation is much more intense, drugs that suppress the immune system as a whole are employed. They suppress immune response by reducing white blood cell counts or interfering with proteins responsible for inflammation. These drugs have more potent side effects and can make the patient susceptible to infection and sickness. Newer drugs on the market include azathioprine, cyclosporine and infliximab. In addition, intravenous corticosteroids are used in combination with immuno-supressors.Since the primary symptom of ulcerative colitis is inflammation of the intestines, almost every drug to treat it is aimed at reducing or interfering with the body's immune responses. All of these drugs have side effects, but they are generally mild. Each of these currently accepted treatments have a proven record of safety and efficacy. Before making decisions about which treatment is best for you or your loved one, speak thoroughly with a physician.