The therapeutic effect of sulfasalazine in ulcerative
colitis is exerted by:
A. Inhibitory action of the unabsorbed drug on
the abnormal colonic flora
B. Breakdown of the drug in colon to release
5-aminosalicylic acid which suppresses
inflammation locally
C. Release of sulfapyridine having antibacterial
property
D. Systemic immunomodulatory action of the
drug
colitis is exerted by:
A. Inhibitory action of the unabsorbed drug on
the abnormal colonic flora
B. Breakdown of the drug in colon to release
5-aminosalicylic acid which suppresses
inflammation locally
C. Release of sulfapyridine having antibacterial
property
D. Systemic immunomodulatory action of the
drug