Description : Select the most appropriate drug for regular prophylactic therapy in a 10 year old child who suffers from exercise induced asthma: A. Oral salbutamol B. Oral theophylline C. Inhaled sodium cromoglycate D. Inhaled salmeterol
Last Answer : C. Inhaled sodium cromoglycate
Description : Which of the following drugs is neither bronchodilator nor anti-inflammatory, but has antihistaminic and mast cell stabilizing activity ? (a) Sodium cromoglycate (b) Ketotifen (c) Beclomethasone dipropionate (d) Mepyramine maleate
Last Answer : Ans: B
Description : 6 A patient of chronic bronchial asthma was maintained on oral prednisolone 20 mg/day for 3 months. It was decided to switch him over to inhaled beclomethasone dipropionate 200 μg 4 times a day. What should ... week and then tapered D. Its dose should be doubled for one week and then tapered (p. 2
Last Answer : C. It should be given at the same dose for one week and then tapered
Description : In the emergency department, the preferred first-line therapy for asthma exacerbation is (a) Theophylline (b) A ß-agonist (c) A corticosteroid (d) Cromolyn sodium (e) An antihistamine
Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s). (a) Inhibits antigen-antibody reaction in the lungs (b) Causes bronchodilatation (c) Reduces bronchial hyperreactivity (d) Both (b) and (c)
Description : Select the drug that is neither bronchodilator nor antiinflammatory, but has antihistaminic and mast cell stabilizing activity: A. Sodium cromoglycate B. Ketotifen C. Beclomethasone dipropionate D. Chlorpheniramine
Last Answer : B. Ketotifen
Description : Inhaled beclomethasone dipropionate should be used only in: A. Acute attack of asthma B. Moderate to severe chronic asthma C. Status asthmaticus D. Asthma not responding to systemic corti- costeroids
Last Answer : B. Moderate to severe chronic asthma
Description : All the following are employed in inhalation therapy of asthma except (a) Beclomethasone (b) Budesonide (c) Dexamethasone (d) Triamcinolone
Last Answer : Ans: C
Description : The most consistent, pronounced and sustained relief of symptoms in chronic bronchial asthma is afforded by (a) ß2 sympathomimetics (b) Anticholinergics (c) Sodium cromoglycate (d) Corticosteroids
Last Answer : Ans: D
Description : A drug administered by inhalation of powder as a prophylactic for asthma is (a) Ephedrine (b) Disodium cromolyn (c) Isoproterenol (d) Ocytriphylline (e) Epinephrine
Description : Budesonide is a (a) Nonsteroidal anti-inflammatory drug (b) High ceiling diuretic (c) Inhaled corticosteroid for asthma (d) Contraceptive
Description : To be a useful inhaled glucocorticoid the drug should have (a) High oral bioavailability (b) Low oral bioavailability (c) Additional bronchodilator activity (d) Prodrug character
Description : In the emergency department, the preferred first-line therapy for asthma exacerbation is (a) Theophyline (b) A ß-agonist (c) A corticosteroid (d) Cromolyn sodium (e) An antihistamine
Description : One of the most common side effect of inhaled beclomethasone dipropionate is: A. Pneumonia B. Oropharyngeal candidiasis C. Atrophic rhinitis D. Pituitary-adrenal suppression
Last Answer : B. Oropharyngeal candidiasis
Description : Which xanthine derivative has no function in asthma ? (a) Theophylline (b) Pentoxyphyllin (c) Enprofylin (d) None of the above
Description : In patients of bronchial asthma inhaled corticosteroids achieve the following except (a) Reduce the need for bronchodilator medication (b) Control an attack of refractory asthma (c) Reduce bronchial hyperreactivity (d) Reverse diminished responsiveness to sympathomimetic bronchodilators
Description : The National Institutes of Health (NIH) guidelines for the treatment of asthma recommended institution of routine inhaled corticosteroids when patients are classified as having greater than or equal to which ... (a) Mild intermittent (b) Mild persistent (c) Moderate persistent (d) Severe persistent
Description : If therapy with multiple drugs causes induction of drug metabolism in your asthma patient, it will (a) Result in increased smooth endoplasmic reticulum (b) Result in increased rough endoplasmic reticulum ... soluble cytoplasmic fraction (d) Require 3-4 months to reach completion (e) Be irreversible
Last Answer : Ans: A
Description : The antiasthma drug which cannot be administered by inhalation is (a) Theophylline (b) Ipratropium bromide (c) Budesonide (d) Terbutaline
Description : The following antiasthma drug is not a bronchodilator: A. Ipratropium bromide B. Theophylline C. Formoterol D. Sodium cromoglycate
Last Answer : D. Sodium cromoglycate
Description : Which of the following is a direct bronchodilator that is most often used in asthma by the oral route? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Which of the following tests is used at home to assess therapy and determine if a patient with asthma should seek emergency care? (a) Forced expiratory volume in one second (FEV1) (b) Forced vital capacity ... ) Total lung capacity (TLC) (d) Peak expiratory flow rate (PEFR) (e) Residual volume (RV)
Description : The primary goals of asthma therapy include all of the following except (a) maintain normal activity levels (b) maintain control of symptoms (c) avoid adverse effects of asthma medications (d) prevent acute exacerbations and chronic symptoms (e) prevent destruction of lung tissue
Last Answer : Ans: E
Description : Bronchodilators are useful in cough (a) Only when cough is non-productive (b) Only when cough is associated with thick sticky secretions (c) Only when reflex bronchoconstriction is associated (d) ... Rise in blood pressure (b) Muscle tremor (c) Hyperglycaemia (d) Central nervous system stimulation
Description : A drug useful in the treatment of asthma but lacking bronchodilator action, is (a) Cromolyn (b) Ephedrine (c) Isoproterenol (d) Metaproterenol (e) Metoprolol
Description : Relatively higher dose of theophylline is required to attain therapeutics plasma concentration in (a) Smokers (b) Congestive heart failure patients (c) Those receiving erythromycin (d) Those receiving cimetidine
Description : Caffeine is more powerful than theophylline in exerting the following action (a) Bronchodilatation (b) Cardiac stimulation (c) Diuresis (d) Augmentation of skeletal muscle contractility
Description : Which of the following is a prophylactic agent that appears to stabilize mast cells? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : Inhaled salbutamol is useful in bronchial asthma for: A. Aborting/terminating asthma attacks B. Round the clock prophylaxis of asthma C. Status asthmaticus D. All of the above
Last Answer : A. Aborting/terminating asthma attacks
Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s): A. Inhibits antigen-antibody reaction in the lungs B. Causes bronchodilatation C. Reduces bronchial hyperreactivity D. Both ‘B’ and ‘C’ are correct
Last Answer : B. Causes bronchodilatation
Description : The most important receptor involved in cytotoxic drug induced vomiting is (a) Histamine H1 receptor (b) Serotonin 5-HT3 receptor (c) Dopamine D2 receptor (d) Opioid µ receptor
Description : Which of the following drugs is administered by intranasal spray/application for systemic action: A. Phenylephrine B. Desmopressin C. Azelastine D. Beclomethasone dipropionate
Last Answer : B. Desmopressin
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial or viral pneumonia (b) Hypersensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : The symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cell (e) Decreased prostaglandin production
Description : Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in ... ) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin
Description : Which of the following is a very longacting ß2 – selective agonist that is used for asthma prophylaxis? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Salmeterol
Description : Acute exacerbations of asthma can be triggered by all of the following except (a) Bacterial of viral pneumonia (b) Hypertsensitivity reaction to penicillin (c) Discontinuation of asthma medication (d) Hot, dry weather (e) Stressful emotional events
Description : In an asthma patient treated with systemic corticosteroids, bronchodilator drugs (a) Are not needed (b) Are contraindicated (c) May be used on ‘as and when required’ basis (d) Are ineffective
Description : H1 antihistaminics are beneficial in (a) All types of allergic disorders (b) Certain type I allergic reactions only (c) Anaphylactic shock(d) Bronchial asthma
Description : Isoxuprine is used to treat (a) Asthma (b) Severe hypotension (c) Nasal congestion (d) Premature labor (e) Hypertension
Description : Which of the following may precipitate an asthma attack? (a) Respiratory acidosis (b) Viran and bacterial infections (c) Respiratory alkalosis (d) Cranberry jiuce (e) Chocolate or Coca Cola
Description : Which of the following agents and dosage regimens is the best choice of treatment for an asthma patient with rheumatoid arthritis who is considered sensitive to aspirin (experiences bronchospasm with use)? ... once a week (d) Azathioprine, 75 mg daily (e) Cyclophosphamide, 100 mg daily
Description : The Symptoms of allergen-mediated asthma result from which of the following? (a) Increased release of mediators from mast cells (b) Increased adrenergic responsiveness of the airways (c) ... bronchial tissue (d) Decreased calcium influx into the mast cells (e) Decreased prostaglandin production
Description : Which of the following terms best describes the antagonism of leukotriene's bronchoconstrictor effect (mediated at leukotriene receptors) by terbutaline (acting a adrenoceptors) in a patient with ... ) Partial agonist (c) Physiologic antagonist (d) Chemical antagonist (e) Noncompetitive antagonist
Description : Which of the following is a nonselective but very potent and efficacious bonchodilator that is not active by the oral route? (a) Aminophyline (b) Cromolyn (c) Epinephrine (d) Ipratropium (e) Metaproterenol
Description : A patient of chronic bronchial asthma maintained on oral prednisolone 20 mg daily and inhaled salbutamol as required develops chest infection. Which of the following measures is recommended: A. ... mg/day C. No change/increase in prednisolone dose D. Substitute prednisolone with inhaled budesonid
Last Answer : C. No change/increase in prednisolone dose
Description : The most consistent, pronounced and sustained relief of symptoms in chronic bronchial asthma is afforded by: A. β2 sympathomimetics B. Anticholinergics C. Sodium cromoglycate D. Corticosteroids
Last Answer : D. Corticosteroids
Description : Sodium cromoglycate has a role in the treatment of the following conditions except: A. Chronic bronchial asthma B. Chronic urticaria C. Chronic allergic rhinitis D. Chronic allergic conjunctivitis
Last Answer : B. Chronic urticaria