DefinitionA polyp biopsyis a diagnostic procedure that takes a sample of or removes polyps (abnormal growths) for examination.Alternative NamesPolyp biopsyHow the test is performedPolyps are outgrowths of tissue that may be attached by a stalk-like structure (a pedicle). They are commonly found in organs with many blood vessels, such as the uterus, colon, and nose. Some polyps are cancerous (malignant) and likely to spread, while others are noncancerous (benign).How a polyp biopsy is taken depends on the location:EGD(esophagogastroduodenoscopy) or other endoscopy is used for the throat, stomach, and small bowel.Colonoscopy or flexible sigmoidoscopy explores the large bowel.Colposcopy-directed biopsy examines the vagina and cervix.For areas of the body that are visible, a topical anesthetic