Description : Majority of drugs cross biological membranes primarily by: A. Passive diffusion B. Facilitated diffusion C. Active transport D. Pinocytosis
Last Answer : A. Passive diffusion
Description : Active transport of a substance across biological membranes has the following characteristics except: A. It is specific B. It is pH dependent C. It is saturable D. It requires metabolic energy
Last Answer : B. It is pH dependent
Description : By which of the following can movement of materials across animal cell membranes be accomplished? I Active transport, II Diffusion, III Pinocytosis (A) I only (B) II only (C) I and II only (D) All I, II, and III
Last Answer : Will be only two.
Description : The absorption of intact protein from the gut in the foetal and newborn animals takes place by (A) Pinocytosis (B) Passive diffusion (C) Simple diffusion (D) Active transport
Last Answer : A
Description : Weakly acidic drugs: A. Are bound primarily to α1 acid glycoprotein in plasma B. Are excreted faster in alkaline urine C. Are highly ionized in the gastric juice D. Do not cross blood-brain barrier
Last Answer : B. Are excreted faster in alkaline urine
Description : 04. The main mechanism of most drugs absorption in GI tract is: a) Active transport (carrier-mediated diffusion) b) Filtration (aqueous diffusion) c) Endocytosis and exocytosis d) Passive diffusion (lipid diffusion)
Last Answer : PHARMACOKINETICS
Description : The exchange of material takes place (A) Only by diffusion (B) Only by active transport (C) Only by pinocytosis (D) All of these
Last Answer : D
Description : The process by which cell can take in fluid and molecules too large to be carried across the plasma membrane by active transport is called a. phagocytosis b. Pinocytosis c. absorption d. diffusion
Last Answer : Pinocytosis
Last Answer : (D) All of these
Description : The most important factor which governs diffusion of drugs across capillaries other than those in the brain is: A. Blood flow through the capillary B. Lipid solubility of the drug C. pKa value of the drug D. pH of the medium
Last Answer : A. Blood flow through the capillary
Description : 3 Diffusion of drugs across cell membrane: A. Is dependent upon metabolic activity of the cell B. Is competitively inhibited by chemically related drugs C. Is affected by extent of ionization of drug molecules D. Exhibits saturation kinetics
Last Answer : C. Is affected by extent of ionization of drug molecules
Description : Drugs which undergo high degree of first-pass metabolism in liver: A. Have low oral bioavailability B. Are excreted primarily in bile C. Are contraindicated in liver disease D. Exhibit zero order kinetics of elimination
Last Answer : A. Have low oral bioavailability
Description : Biotransformation of drugs is primarily directed to: A. Activate the drug B. Inactivate the drug C. Convert lipid soluble drugs into nonlipid soluble metabolites D. Convert nonlipid soluble drugs into lipid soluble metabolites
Last Answer : C. Convert lipid soluble drugs into nonlipid soluble metabolites
Description : How is facilitated diffusion similar to active transport How is it different?
Last Answer : Need answer
Description : Fatty acids can be transported into and out of cell membrane by (A) Active transport (B) Facilitated transport (C) Diffusion (D) Osmosis
Last Answer : B
Description : What do facilitated diffusion and active transport have in common ?
Last Answer : What are the differences between them? Facilitated diffusion can be confused with active transport because in both processes there is participation of membrane proteins. In active transport however the ... it does not require energy. Cell Membrane Review - Image Diversity: active transport
Description : The primary force moving water molecules from the blood plasma to the interstitial fluid is a. active transport b. cotransport with H+ c. facilitated diffusion d. cotransport with Na+ e. filtration
Last Answer : filtration
Description : Sugars depend on which mechanism to enter the cell a. facilitated diffusion b. active transport c. both d. none of them
Last Answer : facilitated diffusion
Description : Which transmembrane movement involves carriers? a. facilitated diffusion b. active transport c. both d. none of them
Last Answer : both
Description : Fructose is absorbed into the blood through mucosa cells of intestine by the process called (a) active transport (b) facilitated transport (c) simple diffusion (d) co-transport mechanism.
Last Answer : (b) facilitated transport
Description : The movement of glucose into a cell occurs by a. Facilitated diffusion. b. Active transport. c. Simple diffusion. d. Phospholipid exchange.
Last Answer : b. Active transport.
Description : Substances insoluble in a membrane are carried across the membrane with the concentration gradient by means of a carrier molecule in a process known as: a) osmosis. b) diffusion. c) active transport. d) facilitated diffusion.
Last Answer : ANSWER: D -- FACILITATED DIFFUSION.
Description : What is the energy source used in active transport through biological membranes ?
Last Answer : The energy necessary for active transport (against the concentration gradient of the transported substance) to occur comes from ATP molecules. The active transportation uses chemical energy from ATP.
Description : The pharmacokinetics of drugs in the neonate differs from that in adults, because their: A. Intestinal transit is fast B. Drug metabolizing enzymes are overactive C. Tubular transport mechanisms are not well developed D. Glomerular filtration rate is high
Last Answer : C. Tubular transport mechanisms are not well developed
Description : A prodrug is: A. The prototype member of a class of drugs B. The oldest member of a class of drugs C. An inactive drug that is transformed in the body to an active metabolite D. A drug that is stored in body tissues and is then gradually released in the circulation
Last Answer : C. An inactive drug that is transformed in the body to an active metabolite
Description : If the effect of combination of two drugs is equal to the sum of their individual effects, the two drugs are exhibiting: A. Potentiation B. Synergism C. Cross tolerance D. Antagonism
Last Answer : B. Synergism
Description : Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include (a) Aqueous diffusion (b) Aqueous hydrolysis (c) Lipid diffusion (d) Pinocytosis or endocytosis (e) Special carrier transport
Last Answer : Ans: E
Description : Glucose is taken back from glomerular filtrate through (a) active transport (b) passive transport (c) osmosis (d) diffusion
Last Answer : (a) active transport
Description : The exchange of gases in the alveoli of the lungs takes place by (a) passive transport (b) active transport (c) osmosis (d) simple diffusion.
Last Answer : d) simple diffusion.
Description : Sodium ions are "pumped" from a region of lower concentration to a region of higher concentration in the nerve cells of humans. This process is an example of (A) Diffusion (B) Passive transport (C) Osmosis (D) Active transport
Last Answer : (D) Active transport
Description : 05. What kind of substances can’t permeate membranes by passive diffusion? a) Lipid-soluble b) Non-ionized substances c) Hydrophobic substances d) Hydrophilic substances 06. A hydrophilic medicinal agent
Last Answer : d) Hydrophilic substances
Description : 07. What is implied by «active transport»? a) Transport of drugs trough a membrane by means of diffusion b) Transport without energy consumption c) Engulf of drug by a cell membrane with a new vesicle formation
Last Answer : d) Transport against concentration gradient
Description : Which of the following features is predicted by the Nicolson–Singer fluid mosaic model of biological membranes? (A) Membrane lipids do not diffuse laterally (B) Membrane lipid is primarily in a monolayer form (C) Membrane lipids freely flip-flop (D) Membrane proteins may diffuse laterally
Last Answer : Answer : D
Description : Without saturation of transport proteins and under same concentration gradient how can the speed of simple diffusion be compared to the speed of facilitated diffusion ?
Last Answer : The action of facilitator proteins in facilitated diffusion makes this type of diffusion faster than simple diffusion under equal concentration gradients of the moved substance.
Description : Thyroid gland takes up circulating iodine (A) By simple diffusion (B) By facilitated diffusion (C) By active uptake (D) In exchange for chloride
Last Answer : Answer : C
Description : Intestinal absorption of calcium occurs by (A) Active takeup (B) Simple diffusion (C) Facilitated diffusion (D) Endocytosis
Last Answer : Answer : A
Description : The mechanism by which neostigmine improves contraction of myasthenic muscle involves: A. Repetitive binding of the acetylcholine molecules to the same receptors at the muscle endplate B. Diffusion of ... Activation of motor end-plate receptors by neostigmine molecules themselves D. All of the above
Last Answer : D. All of the above
Description : The anticholinesterase action of edrophonium is short lasting because termination of its action depends on: A. Dissociation and diffusion of the drug from the enzyme B. Hydrolysis of the drug by the enzyme C. Synthesis of fresh enzyme molecules D. A combination of the above three processes
Last Answer : A. Dissociation and diffusion of the drug from the enzyme
Description : The most vulnerable period of pregnancy for the causation of foetal malformations due to drugs is: A. 18-55 days of gestation B. 56-84 days of gestation C. Second trimester D. 36 weeks onwards
Last Answer : A. 18-55 days of gestation
Description : The following statement is true in relation to drug toxicity' and poisoning': A. The two terms are synonymous B. When a toxic effect requires specific treatment, it is called poisoning C. ... is called poisoning D. Toxicity is caused by drugs while poisoning is caused by other harmful chemicals
Last Answer : C. A toxic effect which endangers life by markedly affecting vital functions is called poisoning
Description : In congestive heart failure patients: A. Volume of distribution of all drugs is increased B. Hepatic clearance of drugs is unaffected C. Orally administered diuretics may not be effective, but the same may work parenterally D. Inotropic action of digoxin is attenuated
Last Answer : C. Orally administered diuretics may not be effective, but the same may work parenterally
Description : The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level
Last Answer : A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened