Description : Active transport of a substance across biological membranes has the following characteristics except: A. It is specific B. It is pH dependent C. It is saturable D. It requires metabolic energy
Last Answer : B. It is pH dependent
Description : Majority of drugs cross biological membranes primarily by: A. Passive diffusion B. Facilitated diffusion C. Active transport D. Pinocytosis
Last Answer : A. Passive diffusion
Last Answer : C. Is affected by extent of ionization of drug molecules
Description : 3 Diffusion of drugs across cell membrane: A. Is dependent upon metabolic activity of the cell B. Is competitively inhibited by chemically related drugs C. Is affected by extent of ionization of drug molecules D. Exhibits saturation kinetics
Description : What is the energy source used in active transport through biological membranes ?
Last Answer : The energy necessary for active transport (against the concentration gradient of the transported substance) to occur comes from ATP molecules. The active transportation uses chemical energy from ATP.
Description : The most important factor which governs diffusion of drugs across capillaries other than those in the brain is: A. Blood flow through the capillary B. Lipid solubility of the drug C. pKa value of the drug D. pH of the medium
Last Answer : A. Blood flow through the capillary
Description : Which of the following is not a feature of active transport of solutes in plants ? (a) Occurs against concentration gradient (b) Non-selective (c) Occurs through membranes (d) Requires ATP
Last Answer : Non-selective
Description : Active and passive transports across cell membrane differ in (a) passive transport is nonselective (b) passive transport is along the concentration gradient while active transport is due to metabolic ... (d) passive transport is confined to anions while active transport is confined to cations.
Last Answer : (b) passive transport is along the concentration gradient while active transport is due to metabolic energy
Description : The following statement is true in relation to drug toxicity' and poisoning': A. The two terms are synonymous B. When a toxic effect requires specific treatment, it is called poisoning C. ... is called poisoning D. Toxicity is caused by drugs while poisoning is caused by other harmful chemicals
Last Answer : C. A toxic effect which endangers life by markedly affecting vital functions is called poisoning
Description : Explain active transport of substances across cell membranes. -Biology
Last Answer : answer:
Description : By which of the following can movement of materials across animal cell membranes be accomplished? I Active transport, II Diffusion, III Pinocytosis (A) I only (B) II only (C) I and II only (D) All I, II, and III
Last Answer : Will be only two.
Description : Glucose uptake by liver cells is (A) Energy-consuming (B) A saturable process (C) Insulin-dependent (D) Insulin-independent
Last Answer : D
Description : The following attribute of a drug tends to reduce its volume of distribution: A. High lipid solubility B. Low ionisation at physiological pH values C. High plasma protein binding D. High tissue binding
Last Answer : C. High plasma protein binding
Description : The pharmacokinetics of drugs in the neonate differs from that in adults, because their: A. Intestinal transit is fast B. Drug metabolizing enzymes are overactive C. Tubular transport mechanisms are not well developed D. Glomerular filtration rate is high
Last Answer : C. Tubular transport mechanisms are not well developed
Description : Induction of drug metabolizing enzymes involves: A. A conformational change in the enzyme protein to favour binding of substrate molecules B. Expression of enzyme molecules on the surface of ... C. Enhanced transport of substrate molecules into hepatocytes D. Increased synthesis of enzyme protein
Last Answer : D. Increased synthesis of enzyme protein
Description : The plasma half life of penicillin-G is longer in the new born because their: A. Plasma protein level is low B. Drug metabolizing enzymes are immature C. Glomerular filtration rate is low D. Tubular transport mechanisms are not well developed
Last Answer : D. Tubular transport mechanisms are not well developed
Description : A prodrug is: A. The prototype member of a class of drugs B. The oldest member of a class of drugs C. An inactive drug that is transformed in the body to an active metabolite D. A drug that is stored in body tissues and is then gradually released in the circulation
Last Answer : C. An inactive drug that is transformed in the body to an active metabolite
Description : Which are the molecules that make possible active transport through membranes ?
Last Answer : Active transport is made by specific membrane proteins. These proteins are called “pumps” because they “pump” the moving substance through the membrane using energy from ATP molecules.
Description : Which of the following statement(s) is/are true concerning water movement across cell membranes? a. Water moves only actively through cell membrane transport proteins b. For most cells of ... cells such as the glomerulus of the kidney actively transport water to maintain hydrostatic pressure
Last Answer : Answer: b, c The energetics of water transport across cell membranes is simplified by the fact that water moves only passively due to gradients of hydrostatic pressure or water ... water is distributed at equilibrium. Water distribution is determined entirely by solute to solute distribution
Description : Use of an emetic to remove the ingested poison is contraindicated in following poisonings except that by: A. Strychnine B. Caustic soda C. Ferrous sulfate D. Kerosene
Last Answer : C. Ferrous sulfate
Description : Drugs acting through receptors exhibit the following features except: A. Structural specificity B. High potency C. Competitive antagonism D. Dependence of action on lipophilicity
Last Answer : D. Dependence of action on lipophilicity
Description : Transdermal drug delivery systems offer the following advantages except: A. They produce high peak plasma concentration of the drug B. They produce smooth and nonfluctuating plasma concentration of the ... the achieved plasma drug concentration D. They avoid hepatic first-pass metabolism of the drug
Last Answer : A. They produce high peak plasma concentration of the drug
Description : To be used as a topically applied ocular beta blocker a drug should have the following properties except: A. Strong local anaesthetic activity B. High lipophilicity C. High ocular capture D. Low systemic activity
Last Answer : A. Strong local anaesthetic activity
Description : Actions of pilocarpine include the following except: A. Sweating B. Salivation C. Miosis D. Cycloplegia
Last Answer : D. Cycloplegia
Description : Cholinergic muscarinic receptor stimulation produces the following effects except: A. Sweating B. Rise in blood pressure C. Bradycardia D. Urination
Last Answer : B. Rise in blood pressure
Description : Drug metabolism can be induced by the following factors except: A. Cigarette smoking B. Acute alcohol ingestion C. Exposure to insecticides D. Consumption charcoal broiled meat
Last Answer : B. Acute alcohol ingestion
Description : The following statement is not true of log dose-response curve: A. It is almost linear except at the ends B. It is a rectangular hyperbola C. It facilitates comparison of different agonists D. It can help in discriminating between competitive and noncompetitive antagonists
Last Answer : B. It is a rectangular hyperbola
Description : All of the following subserve as intracellular second messengers in receptor mediated signal transduction except: A. Cyclic AMP B. Inositol trisphosphate C. Diacyl glycerols D. G proteins
Last Answer : D. G proteins
Last Answer : A
Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.
Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.
Description : What is true in relation to drug receptors: A. All drugs act through specific receptors B. All drug receptors are located on the surface of the target cells C. Agonists induce a conformational change in the receptor D. Partial agonists have low affinity for the receptor
Last Answer : C. Agonists induce a conformational change in the receptoR
Description : Which of the following adverse drug reactions is due to a specific genetic abnormality: A. Tetracycline induced sunburn like skin lesions B. Quinidine induced thrombocytopenia C. Metoclopramide induced muscle dystonia D. Primaquine induced massive haemolysis
Last Answer : D. Primaquine induced massive haemolysis
Last Answer : C. Agonists induce a conformational change in the receptor
Description : Which of the following features are present in blood chemistry in uncompensated metabolic alkalosis except? (A) Increased pH (B) Increased bicarbonate (C) Normal chloride (D) Normal pCO2
Last Answer : Answer : D
Description : The horizontal line which cuts across 'L1' shown in figure 'A' of the illustration indicates a/an ______________. EL-0091 A. iron core B. saturable core C. air gap D. capacitive coupling
Last Answer : Answer: B
Description : What are biological membranes? -Biology
Description : Which of the following features is predicted by the Nicolson–Singer fluid mosaic model of biological membranes? (A) Membrane lipids do not diffuse laterally (B) Membrane lipid is primarily in a monolayer form (C) Membrane lipids freely flip-flop (D) Membrane proteins may diffuse laterally
Description : The following is true of clarithromycin except: A. It produces less gastric irritation and pain than erythromycin B. It is the most active macrolide antibiotic against Helicobacter pylori ... terfenadine or cisapride to cause cardiac arrhythmias D. It exhibits dose dependent elimination kinetics
Last Answer : C. It does not interact with terfenadine or cisapride to cause cardiac arrhythmias
Description : All the following statements describing lipids are true except (A) They usually associate by covalent interactions (B) They are structurally components of membranes (C) They are an intracellular energy source (D) They are poorly soluble in H2O
Last Answer : Answer : A
Description : The process by which cell can take in fluid and molecules too large to be carried across the plasma membrane by active transport is called a. phagocytosis b. Pinocytosis c. absorption d. diffusion
Last Answer : Pinocytosis