Adrenergic β 1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity

Adrenergic
β 1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity
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Answer :

C. Withdrawal is less likely to exacerbate angina pectoris
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Adrenergic β1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity

Description : Adrenergic β1 selective blockers offer the following advantages except: A. Lower propensity to cause bronchospasm B. Less prone to produce cold hands and feet as side effect C. Withdrawal is less likely to exacerbate angina pectoris D. Less liable to impair exercise capacity

Last Answer : C. Withdrawal is less likely to exacerbate angina pectoris

β-adrenergic blockers are indicated in the following conditions except: A. Hypertrophic cardiomyopathy B. Congestive heart failure C. Vasospastic angina pectoris D. Dissecting aortic aneurysm

Description : β-adrenergic blockers are indicated in the following conditions except: A. Hypertrophic cardiomyopathy B. Congestive heart failure C. Vasospastic angina pectoris D. Dissecting aortic aneurysm

Last Answer : C. Vasospastic angina pectoris

β -adrenergic blockers are indicated in the following conditions except: A. Hypertrophic cardiomyopathy B. Congestive heart failure C. Vasospastic angina pectoris D. Dissecting aortic aneurysm

Description : β -adrenergic blockers are indicated in the following conditions except: A. Hypertrophic cardiomyopathy B. Congestive heart failure C. Vasospastic angina pectoris D. Dissecting aortic aneurysm

Last Answer : C. Vasospastic angina pectoris

Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris, because: A. They antagonise each other’s side effects B. Nitrates primarily reduce preload while calcium channel blockers primarily reduce after-load C. Nitrates increase coronary flow while calcium channel blockers reduce ca

Description : Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris, because: A. They antagonise each other's side effects B. Nitrates primarily ... primarily reduce after-load C. Nitrates increase coronary flow while calcium channel blockers reduce ca

Last Answer : B. Nitrates primarily reduce preload while calcium channel blockers primarily reduce after-load

n the treatment of hypertension the beta adrenergic blockers have the following advantage: A. They have minimal effect on work capacity, sleep quality and libido B. They do not cause postural hypotension C. Used alone, they have high ceiling antihypertensive efficacy D. They can be used in combination with any other antihypertensive drug

Description : n the treatment of hypertension the beta adrenergic blockers have the following advantage: A. They have minimal effect on work capacity, sleep quality and libido B. They do not cause ... high ceiling antihypertensive efficacy D. They can be used in combination with any other antihypertensive drug

Last Answer : B. They do not cause postural hypotension

The basis for use of β-adrenergic blockers in congestive heart failure (CHF) is: A. They exert positive inotropic effect in CHF B. They counteract deleterious effect of sympathetic overactivity on the myocardium C. They exert antiischaemic effect on the heart D. They prevent cardiac arrhythmias

Description : The basis for use of β-adrenergic blockers in congestive heart failure (CHF) is: A. They exert positive inotropic effect in CHF B. They counteract deleterious effect of sympathetic overactivity on the myocardium C. They exert antiischaemic effect on the heart D. They prevent cardiac arrhythmias

Last Answer : B. They counteract deleterious effect of sympathetic overactivity on the myocardium

The basis for use of β -adrenergic blockers in congestive heart failure (CHF) is: A. They exert positive inotropic effect in CHF B. They counteract deleterious effect of sympathetic overactivity on the myocardium C. They exert antiischaemic effect on the heart D. They prevent cardiac arrhythmias

Description : The basis for use of β -adrenergic blockers in congestive heart failure (CHF) is: A. They exert positive inotropic effect in CHF B. They counteract deleterious effect of sympathetic overactivity on the myocardium C. They exert antiischaemic effect on the heart D. They prevent cardiac arrhythmias

Last Answer : B. They counteract deleterious effect of sympathetic overactivity on the myocardium

The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation

Description : The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation

Last Answer : B. Bradycardia

Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris because (a) They antagonize each other’s side effects (b) Nitrates primarily reduce preload while calcium channel blockers primarily reduce after load (c) Nitrates increase coronary flow while calcium (d) Both (b) and (c)

Description : Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris because (a) They antagonize each other's side effects (b) Nitrates primarily reduce preload while calcium ... load (c) Nitrates increase coronary flow while calcium (d) Both (b) and (c)

Last Answer : Ans: B

Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Description : Enalapril differs from captopril in that: A. It blocks angiotensin II receptors B. It does not produce cough as a side effect C. It is less liable to cause abrupt first dose hypotension D. It has a shorter duration of action

Last Answer : C. It is less liable to cause abrupt first dose hypotension

Low dose therapy with the following category of antihypertensive drugs has been found to be more advantageous in the long-term than high dose therapy with the same drugs: A. β adrenergic blockers B. α1 adrenergic blockers C. Central sympatholytics D. Diuretics

Description : Low dose therapy with the following category of antihypertensive drugs has been found to be more advantageous in the long-term than high dose therapy with the same drugs: A. β adrenergic blockers B. α1 adrenergic blockers C. Central sympatholytics D. Diuretics

Last Answer : D. Diuretics

In patients of congestive heart failure, β-adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct

Description : In patients of congestive heart failure, β-adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct

Last Answer : D. Both B and C are correct

Currently, the first choice drug for open angle glaucoma is: A. Miotic eye drops B. Ocular α2 adrenergic agonists C. Ocular prostaglandin analogues D. Ocular β adrenergic blockers

Description : Currently, the first choice drug for open angle glaucoma is: A. Miotic eye drops B. Ocular α2 adrenergic agonists C. Ocular prostaglandin analogues D. Ocular β adrenergic blockers

Last Answer : D. Ocular β adrenergic blockers

In patients of congestive heart failure, β -adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct

Description : In patients of congestive heart failure, β -adrenergic blockers: A. Are absolutely contraindicated B. Can prolong survival C. Can improve haemodynamics after compensation has been restored D. Both B and C are correct

Last Answer : D. Both B and C are correct

Indications for the use of antiplatelet drugs include the following except: A. Secondary prophylaxis of myocardial infarction B. Unstable angina pectoris C. Disseminated intravascular coagulation D. Stroke prevention in patients with transient ischaemic attacks

Description : Indications for the use of antiplatelet drugs include the following except: A. Secondary prophylaxis of myocardial infarction B. Unstable angina pectoris C. Disseminated intravascular coagulation D. Stroke prevention in patients with transient ischaemic attacks

Last Answer : C. Disseminated intravascular coagulation

Complications of over treatment with thyroxine include the following except: A. Auricular fibrillation B. Angina pectoris C. Congestive heart failure D. Acceleration of atherosclerosis

Description : Complications of over treatment with thyroxine include the following except: A. Auricular fibrillation B. Angina pectoris C. Congestive heart failure D. Acceleration of atherosclerosis

Last Answer : D. Acceleration of atherosclerosis

17.6 Complications of over treatment with thyroxine include the following except: A. Auricular fibrillation B. Angina pectoris C. Congestive heart failure D. Acceleration of atherosclerosis

Description : 17.6 Complications of over treatment with thyroxine include the following except: A. Auricular fibrillation B. Angina pectoris C. Congestive heart failure D. Acceleration of atherosclerosis

Last Answer : D. Acceleration of atherosclerosis

The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is: A. Increase in total coronary blood flow B. Redistribution of coronary blood flow C. Reduction of cardiac preload D. Reduction of cardiac afterload

Description : The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is: A. Increase in total coronary blood flow B. Redistribution of coronary blood flow C. Reduction of cardiac preload D. Reduction of cardiac afterload

Last Answer : C. Reduction of cardiac preload

Which of the following is not the basis for subclassifying β adrenergic receptors into β1 and β2 : A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location

Description : Which of the following is not the basis for subclassifying β adrenergic receptors into β1 and β2 : A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location

Last Answer : C. Transducer pathway of response effectuation

Which of the following is not the basis for subclassifying β adrenergic receptors into β 1 and β 2: A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location

Description : Which of the following is not the basis for subclassifying β adrenergic receptors into β 1 and β 2: A. Selectivity of agonists B. Selectivity of antagonists C. Transducer pathway of response effectuation D. Organ selective location

Last Answer : C. Transducer pathway of response effectuation

he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect C. It can inhibit insulin release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori

Description : he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to ... release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori

Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect

Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients with low blood pressure C. Its action lasts less than 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil

Description : Use of adenosine for terminating an episode of paroxysmal supraventricular tachycardia has the following advantages except: A. It does not produce any side effect B. It can be given to patients ... 1 min after bolus intravenous injection D. It is effective in patients not responding to verapamil

Last Answer : A. It does not produce any side effect

Beneficial effects of β-adrenoceptor blockers in CHF include the following except: A. Antagonism of ventricular wall stress enhancing action of sympathetic overactivity B. Antagonism of vasoconstriction due to sympathetic overactivity C. Prevention of pathological remodeling of ventricular myocardium D. Prevention of dangerous cardiac arrhythmias

Description : Beneficial effects of β-adrenoceptor blockers in CHF include the following except: A. Antagonism of ventricular wall stress enhancing action of sympathetic overactivity B. Antagonism ... Prevention of pathological remodeling of ventricular myocardium D. Prevention of dangerous cardiac arrhythmias

Last Answer : B. Antagonism of vasoconstriction due to sympathetic overactivity

A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but blood sugar level and lipid profile were normal. Select the most suitable antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

Description : A 40-year-old politician suffered from attacks of chest pain diagnosed as angina pectoris. He had a tense personality, resting heart rate was 96/min, blood pressure 170/104 mm Hg, but ... antihypertensive for initial therapy in his case: A. Nifedipine B. Hydrochlorothiazide C. Atenolol D. Methyldopa

Last Answer : C. Atenolol

Propranolol should not be prescribed for a patient of angina pectoris who is already receiving: A. Nifedipine B. Felodipine C. Verapamil D. Isosorbide mononitrate

Description : Propranolol should not be prescribed for a patient of angina pectoris who is already receiving: A. Nifedipine B. Felodipine C. Verapamil D. Isosorbide mononitrate

Last Answer : C. Verapami

A patient suffers from episodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from: A. Angina pectoris B. Biliary colic C. Esophageal spasm D. Any of the abov

Description : A patient suffers from episodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from: A. Angina pectoris B. Biliary colic C. Esophageal spasm D. Any of the abov

Last Answer : D. Any of the abov

Choose the correct statement about the action of nitrates on coronary vessels: A. They mitigate angina pectoris by increasing total coronary flow B. They preferentially dilate conducting arteries without affecting resistance arterioles C. They preferentially dilate autoregulatory arterioles without affecting the larger arteries D. They increase subepicardial blood flow without affecting subendocardial blood flow

Description : Choose the correct statement about the action of nitrates on coronary vessels: A. They mitigate angina pectoris by increasing total coronary flow B. They preferentially dilate conducting ... the larger arteries D. They increase subepicardial blood flow without affecting subendocardial blood flow

Last Answer : B. They preferentially dilate conducting arteries without affecting resistance arterioles

The following drug is used to reduce the frequency of angina pectoris as well as to terminate an acute attack: A. Isosorbide dinitrate B. Pentaerythritol tetranitrate C. Diltiazem D. Dipyridamole

Description : The following drug is used to reduce the frequency of angina pectoris as well as to terminate an acute attack: A. Isosorbide dinitrate B. Pentaerythritol tetranitrate C. Diltiazem D. Dipyridamole

Last Answer : A. Isosorbide dinitrate

Digoxin is contraindicated in: A. Angina pectoris patients B. Ventricular tachycardia C. Hypertensive patients D. Complete heart-block

Description : Digoxin is contraindicated in: A. Angina pectoris patients B. Ventricular tachycardia C. Hypertensive patients D. Complete heart-block

Last Answer : B. Ventricular tachycardia

The calcium channel blocker used for prophylaxis of migraine but not for angina pectoris is: A. Verapamil B. Diltiazem C. Flunarizine D. Amlodipine

Description : The calcium channel blocker used for prophylaxis of migraine but not for angina pectoris is: A. Verapamil B. Diltiazem C. Flunarizine D. Amlodipine

Last Answer : C. Flunarizine

The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide

Description : The following antiepileptic drug is most likely to impair learning and memory, and produce behavioral abnormalities in children: A. Valproic acid B. Phenobarbitone C. Phenytoin D. Ethosuximide

Last Answer : B. Phenobarbitone

Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs C. They do not worsen blood lipid profile D. They do not impair work performance

Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance

Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs

Methyldopa differs from clonidine in the following respect: A. It is less likely to cause rebound hypertension on sudden discontinuation B. It does not reduce plasma renin activity C. It has a central as well as peripheral site of antihypertensive action D. It does not produce central side effect

Description : Methyldopa differs from clonidine in the following respect: A. It is less likely to cause rebound hypertension on sudden discontinuation B. It does not reduce plasma renin activity C. It has a central as well as peripheral site of antihypertensive action D. It does not produce central side effect

Last Answer : A. It is less likely to cause rebound hypertension on sudden discontinuation

Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality C. They compromise quality of life more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath

Description : Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They ... more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath

Last Answer : B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality

The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation

Description : The nonselective α adrenergic blockers produce the following actions except: A. Postural hypotension B. Bradycardia C. Miosis D. Inhibition of ejaculation

Last Answer : B. Bradycardia

The following is true of propafenone except: A. It is a weak Na+ channel blocker B. It markedly delays recovery of myocardial Na+ channels C. It has additional β-adrenergic blocking property D. It slows anterograde as well as retrograde conduction in the WPW bypass tract

Description : The following is true of propafenone except: A. It is a weak Na+ channel blocker B. It markedly delays recovery of myocardial Na+ channels C. It has additional β-adrenergic blocking property D. It slows anterograde as well as retrograde conduction in the WPW bypass tract

Last Answer : A. It is a weak Na+ channel blocker

Insulin release from pancreatic β cells is augmented by the following except: A. Ketone bodies B. Glucagon C. Vagal stimulation D. Alfa adrenergic agonists

Description : Insulin release from pancreatic β cells is augmented by the following except: A. Ketone bodies B. Glucagon C. Vagal stimulation D. Alfa adrenergic agonists

Last Answer : D. Alfa adrenergic agonist

The monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance

Description : The monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance

Last Answer : B. They cause less hypoglycaemic reactions

he monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance

Description : he monocomponent insulin preparations differ from the conventional preparations in the following respects except: A. They are less allergenic B. They cause less hypoglycaemic reactions C. They cause less lipodystrophy D. They are less liable to induce insulin resistance

Last Answer : B. They cause less hypoglycaemic reactions

Advantages of selective serotonin reuptake inhibitors (SSRIs) include the following except: A. No interference with ejaculation and orgasm B. Minimal sedative action C. Unlikely to cause fall in BP D. Lack of seizure precipitating potential

Description : Advantages of selective serotonin reuptake inhibitors (SSRIs) include the following except: A. No interference with ejaculation and orgasm B. Minimal sedative action C. Unlikely to cause fall in BP D. Lack of seizure precipitating potential

Last Answer : A. No interference with ejaculation and orgasm

The following is true of bupropion except: A. It inhibits dopamine reuptake along with inhibiting noradrenaline reuptake B. It produces sedation as a side effect C. It is being used as an aid for smoking cessation D. It is likely to produce seizures in overdose

Description : The following is true of bupropion except: A. It inhibits dopamine reuptake along with inhibiting noradrenaline reuptake B. It produces sedation as a side effect C. It is being used as an aid for smoking cessation D. It is likely to produce seizures in overdose

Last Answer : B. It produces sedation as a side effect

Which racial difference in response to drugs has been mentioned incorrectly below: A. Africans require higher concentration of atropine to dilate pupils B. Black races are more responsive to antihypertensive action of beta blockers C. Japanese are more prone to develop SMON due to halogenated hydroxyquinolines D. Chloramphenicol induced aplastic anaemia is rare among Indians

Description : Which racial difference in response to drugs has been mentioned incorrectly below: A. Africans require higher concentration of atropine to dilate pupils B. Black races are more responsive ... SMON due to halogenated hydroxyquinolines D. Chloramphenicol induced aplastic anaemia is rare among Indians

Last Answer : B. Black races are more responsive to antihypertensive action of beta blockers

Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve

Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve

Last Answer : C. Do not block any effect of injected adrenaline

Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation

Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation

Last Answer : C. Do not block any effect of injected adrenaline

Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Last Answer : C. It does not concurrently enhance noradrenaline release

Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Description : Prazosin is an effective antihypertensive while nonselective α adrenergic blockers are not because: A. It is the only orally active α blocker B. It improves plasma lipid profile C. It does not concurrently enhance noradrenaline release D. It improves urine flow in males with prostatic hypertrophy

Last Answer : C. It does not concurrently enhance noradrenaline release

In hyperthyroidism, β adrenergic blockers are used: A. To induce euthyroid state B. As definitive therapy C. For rapid control of certain symptoms while awaiting response to carbimazole D. To reduce basal metabolic rate

Description : Select the β-adrenergic blocker that has additional α1 blocking, vasodilator and antioxidant properties: A. Carvedilol B. Celiprolol C. Acebutolol D. Metoprolol

Last Answer : C. Acebutolol

In a patient of myocardial infarction, β adrenergic blockers are used with the following aim/aims: A. To reduce the incidence of reinfarction B. To prevent cardiac arrhythmias C. To limit size of the infarct D. All of the above

Description : In a patient of myocardial infarction, β adrenergic blockers are used with the following aim/aims: A. To reduce the incidence of reinfarction B. To prevent cardiac arrhythmias C. To limit size of the infarct D. All of the above

Last Answer : D. All of the above