The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is: A. Increase in total coronary blood flow B. Redistribution of coronary blood flow C. Reduction of cardiac preload D. Reduction of cardiac afterload

Question

The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is: A. Increase in total coronary blood flow B. Redistribution of coronary blood flow C. Reduction of cardiac preload D. Reduction of cardiac afterload

The primary mechanism of beneficial effect of glyceryl
trinitrate in classical angina pectoris is:
A. Increase in total coronary blood flow
B. Redistribution of coronary blood flow
C. Reduction of cardiac preload
D. Reduction of cardiac afterload

asked Jul 23, 2021 by anonymous

1 Answer

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The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is (a) Increase in total coronary blood flow (b) Redistribution of coronary blood flow (c) Reduction of cardiac preload (d) Reduction of cardiac after load

Description : The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is (a) Increase in total coronary blood flow (b) Redistribution of coronary blood flow (c) Reduction of cardiac preload (d) Reduction of cardiac after load

Last Answer : Ans: C

Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris, because: A. They antagonise each other’s side effects B. Nitrates primarily reduce preload while calcium channel blockers primarily reduce after-load C. Nitrates increase coronary flow while calcium channel blockers reduce ca

Description : Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris, because: A. They antagonise each other's side effects B. Nitrates primarily ... primarily reduce after-load C. Nitrates increase coronary flow while calcium channel blockers reduce ca

Last Answer : B. Nitrates primarily reduce preload while calcium channel blockers primarily reduce after-load

A patient suffers from episodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from: A. Angina pectoris B. Biliary colic C. Esophageal spasm D. Any of the abov

Description : A patient suffers from episodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from: A. Angina pectoris B. Biliary colic C. Esophageal spasm D. Any of the abov

Last Answer : D. Any of the abov

Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris because (a) They antagonize each other’s side effects (b) Nitrates primarily reduce preload while calcium channel blockers primarily reduce after load (c) Nitrates increase coronary flow while calcium (d) Both (b) and (c)

Description : Though nitrates and calcium channel blockers are both vasodilators, they are used concurrently in angina pectoris because (a) They antagonize each other's side effects (b) Nitrates primarily reduce preload while calcium ... load (c) Nitrates increase coronary flow while calcium (d) Both (b) and (c)

Last Answer : Ans: B

Choose the correct statement about the action of nitrates on coronary vessels: A. They mitigate angina pectoris by increasing total coronary flow B. They preferentially dilate conducting arteries without affecting resistance arterioles C. They preferentially dilate autoregulatory arterioles without affecting the larger arteries D. They increase subepicardial blood flow without affecting subendocardial blood flow

Description : Choose the correct statement about the action of nitrates on coronary vessels: A. They mitigate angina pectoris by increasing total coronary flow B. They preferentially dilate conducting ... the larger arteries D. They increase subepicardial blood flow without affecting subendocardial blood flow

Last Answer : B. They preferentially dilate conducting arteries without affecting resistance arterioles

Major beneficial effect of nitrates in classical angina is due to (a) Dilation of veins more than arteries (b) Increase in total coronary blood flow (c) An increase in the end diastolic size of the heart (d) An increase in the heart rate

Description : Major beneficial effect of nitrates in classical angina is due to (a) Dilation of veins more than arteries (b) Increase in total coronary blood flow (c) An increase in the end diastolic size of the heart (d) An increase in the heart rate

Last Answer : Ans: A

Blood flow in the following vascular bed generally decreases under the influence of glyceryl trinitrate: A. Coronary B. Cutaneous C. Renal D. Cranial

Description : Blood flow in the following vascular bed generally decreases under the influence of glyceryl trinitrate: A. Coronary B. Cutaneous C. Renal D. Cranial

Last Answer : C. Renal

A drug which preferentially dilates autoregulatory coronary arterioles with little effect on large conducting vessels is likely to: A. Evoke coronary steal phenomenon B. Mitigate classical angina but not variant angina C. Decrease total coronary blood flow in healthy subjects D. Avert ECG changes of ischaemia

Description : A drug which preferentially dilates autoregulatory coronary arterioles with little effect on large conducting vessels is likely to: A. Evoke coronary steal phenomenon B. Mitigate classical angina but not ... . Decrease total coronary blood flow in healthy subjects D. Avert ECG changes of ischaemia

Last Answer : A. Evoke coronary steal phenomenon

The agent given sublingually in an acute attack of angina pectoris is (a) Glyceryl trinitrate (b) Amyl nitrite (c) Erythrital tetranitrate (d) Pentaerythritol tetranitrate

Description : The agent given sublingually in an acute attack of angina pectoris is (a) Glyceryl trinitrate (b) Amyl nitrite (c) Erythrital tetranitrate (d) Pentaerythritol tetranitrate

Last Answer : Ans: A

A patient suffers from spisodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from (a) Angina pectoris (b) Biliary colic (c) Esophageal spasm (d) All of the above

Description : A patient suffers from spisodic pain diffusely localized over the chest and upper abdomen, which is relieved by sublingual glyceryl trinitrate. He could be suffering from (a) Angina pectoris (b) Biliary colic (c) Esophageal spasm (d) All of the above

Last Answer : Ans: D

Choose the correct statement about the action of nitrates on coronary vessels (a) They mitigate angina pectoris by increasing total coronary flow (b) They preferentially dilate conducting arteries without affecting resistance arterioles (c) They preferentially dilate autoregulatory arterioles without affecting the larger arteries (d) They increase subepicardial blood flow without affecting subendocardial blood flow

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Last Answer : Ans: B

‘Coronary steal phenomenon’ has been noted most frequently with: A. Glyceryl trinitrate B. Dipyridamole C. Propranolol D. Diltiazem

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Last Answer : B. Dipyridamole

Which vasodilator is most suitable for a patient of CHF who is symptomatic even at rest and has a central venous pressure of 25 mm Hg and cardiac index 1.8 L/min/m2 : A. Glyceryl trinitrate B. Enalapril C. Hydralazine D. Nifedipine

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Last Answer : B. Enalapril

Which of the following terms describes the amount of blood ejected per heartbeat? a) Stroke volume Stroke volume is determined by preload, afterload, and contractility. b) Cardiac output Cardiac output is the amount of blood pumped by each ventricle during a given period and is computed by multiplying the stroke volume of the heart by the heart rate. c) Ejection fraction Ejection Fraction is the percentage of the end-diastolic volume that is ejected with each stroke, measured at 42–50% in the normal heart. d) Afterload Afterload is defined as the pressure that the ventricular myocardium must overcome to eject blood during systole and is one of the determinants of stroke volume.

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Last Answer : a) Stroke volume Stroke volume is determined by preload, afterload, and contractility.

Which of the following vasoactive drugs used in treating shock results in reduced preload and afterload, reducing oxygen demand of the heart? a) Nitroprusside (Nipride) A disadvantage of nitroprusside is that it causes hypotension. b) Dopamine (Intropin) Dopamine improves contractility, increases stroke volume, and increases cardiac output. c) Epinephrine (adrenaline) Epinephrine improves contractility, increases stroke volume, and increases cardiac output. d) Methoxamine (Vasoxyl) Methoxamine increases blood pressure by vasoconstriction.

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Vasoactive drugs which cause the arteries and veins to dilate, thereby shunting much of the intravascular volume to the periphery and causing a reduction in preload and afterload include agents such as a) Sodium nitroprusside (Nipride) Sodium nitroprusside is used in the treatment of cardiogenic shock. b) Norepinephrine (Levophed) Norepinephrine (Levophed) is a vasopressor that is used to promote perfusion to the heart and brain. c) Dopamine (Inotropin) Dopamine (Inotropin) tends to increase the workload of the heart by increasing oxygen demand; thus, it is not administered early in the treatment of cardiogenic shock. d) Furosemide (Lasix) Furosemide (Lasix) is a loop diuretic that reduces intravascular fluid volume.

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Morphine affords symptomatic relief of dyspnoea in acute left ventricular failure by the following mechanisms except: A. Bronchodilatation B. Depression of respiratory centre C. Reduction in cardiac preload D. Shift of blood from pulmonary to systemic circuit

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Last Answer : A. Bronchodilatation

‘Coronary steal phenomenon’ has been noted most frequently with (a) Glyceryl trinitrate (b) Dipyridamole (c) Propranolol (d) Diltiazem

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Last Answer : Ans: B

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Last Answer : C. Withdrawal is less likely to exacerbate angina pectoris

The most likely mechanism of antihypertensive action of thiazide diuretics in the long-term is: A. Reduction of circulating blood volume B. Reduction in cardiac output C. Decreased sympathetic tone D. Reduction in total peripheral vascular resistance and improved compliance of resistance vessels

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Last Answer : D. Reduction in total peripheral vascular resistance and improved compliance of resistance vessels

The following procedure for rapid lowering of BP in hypertensive urgency/emergency has been abandoned: A. Sublingual/oral nifedipine B. Intravenous glyceryl trinitrate infusion C. Intravenous sodium nitroprusside infusion D. Intravenous esmolol injection

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Last Answer : A. Sublingual/oral nifedipine

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Description : Tolerance does not develop to the vasodilator action of sodium nitroprusside while it develops to glyceryl trinitrate because: A. Intact sod. nitroprusside molecule acts like nitric oxide B. Enzymes which ... a long duration of action D. Sod. nitroprusside has additional K+ channel opening action

Last Answer : B. Enzymes which generate nitric oxide from nitroprusside are different

Select the vasodilator that is administered only by slow intravenous infusion and dilates both resistance as well as capacitance vessels: A. Minoxidil B. Diazoxide C. Sodium nitroprusside D. Glyceryl trinitrate

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A patient of acute myocardial infarction being treated in intensive care unit developed left ventricular failure with raised central venous pressure. It was decided to use glyceryl trinitrate. Which route/method of administration would be most suitable: A. Sublingual B. Oral C. Intravenous bolus injection D. Slow intravenous infusion

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Select the organic nitrate which undergoes minimal first-pass metabolism in the liver: A. Glyceryl trinitrate B. Isosorbide dinitrate C. Isosorbide mononitrate D. Erythrityl tetranitrate

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he following is true of nifedipine except: A. It can aggravate urine voiding difficulty in elderly males with prostatic hypertrophy B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect C. It can inhibit insulin release from pancreas D. At high doses it can paradoxically increase the frequency of angina pectori

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Last Answer : B. It promotes Na+ retention by a renal tubular action to cause ankle oedema as side effect

Morphine induced fall in blood pressure involves the following factors except: A. Direct cardiac depression B. Direct reduction of vascular tone C. Vasomotor centre depression D. Histamine release

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anonymous · Answer 1 · 2021-07-23T23:58:04+0000

Answer :

C. Reduction of cardiac preload

answered Jul 23, 2021 by anonymous

The primary mechanism of beneficial effect of glyceryl trinitrate in classical angina pectoris is: A. Increase in total coronary blood flow B. Redistribution of coronary blood flow C. Reduction of cardiac preload D. Reduction of cardiac afterload

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