Choose the most suitable antihypertensive drug for a
45-year-old male company executive who has a
travelling job. His blood pressure is 160/100 mm Hg,
and he is a diabetic controlled with glibenclamide
5 mg twice a day:
A. Propranolol
B. Enalapril
C. Clonidine
D. Hydrochlorothiazide (p. 504)
Note: In this patient the other drugs are not
suitable for the following reasons:
Propranolol: Can vitiate diabetes control and
prolong hypoglycaemia if it occurs. Also it is
more likely to impair work capacity and sexual
function.
Clonidine: This patient with a travelling job is
likely to miss some doses → rebound hypertension.
Hydrochlorothiazide: May worsen diabetes;
more likely to produce weakness, fatigue and
impotenc
45-year-old male company executive who has a
travelling job. His blood pressure is 160/100 mm Hg,
and he is a diabetic controlled with glibenclamide
5 mg twice a day:
A. Propranolol
B. Enalapril
C. Clonidine
D. Hydrochlorothiazide (p. 504)
Note: In this patient the other drugs are not
suitable for the following reasons:
Propranolol: Can vitiate diabetes control and
prolong hypoglycaemia if it occurs. Also it is
more likely to impair work capacity and sexual
function.
Clonidine: This patient with a travelling job is
likely to miss some doses → rebound hypertension.
Hydrochlorothiazide: May worsen diabetes;
more likely to produce weakness, fatigue and
impotenc