Description : Theophylline is believed to benefit asthma patients by exerting the following actions except: A. Bronchodilatation B. Augmentation of diaphragmatic contractility C. Reduced mediator release D. Inhibition of antigen: antibody reaction
Last Answer : D. Inhibition of antigen: antibody reaction
Description : Select the antiasthma drug which cannot be administered by inhalation: A. Theophylline B. Ipratropium bromide C. Budesonide D. Terbutaline
Last Answer : A. Theophylline
Description : Caffeine is more powerful than theophylline in exerting the following action: A. Bronchodilatation B. Cardiac stimulation C. Diuresis D. Augmentation of skeletal muscl contractility
Last Answer : D. Augmentation of skeletal muscl contractility
Description : In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s): A. Inhibits antigen-antibody reaction in the lungs B. Causes bronchodilatation C. Reduces bronchial hyperreactivity D. Both ‘B’ and ‘C’ are correct
Last Answer : B. Causes bronchodilatation
Description : Select the fluoroquinolone which has high oral bioavailability, longer elimination half-life and which does not inhibit metabolism of theophylline: A. Norfloxacin B. Pefloxacin C. Lomefloxacin D. Ciprofloxacin
Last Answer : C. Lomefloxacin
Description : The following drug displaces plasma protein bound phenytoin as well as decreases its metabolism: A. Carbamazepine B. Sodium valproate C. Cimetidine D. Chloramphenicol
Last Answer : B. Sodium valproate
Description : Inhaled beclomethasone dipropionate should be used only in: A. Acute attack of asthma B. Moderate to severe chronic asthma C. Status asthmaticus D. Asthma not responding to systemic corti- costeroids
Last Answer : B. Moderate to severe chronic asthma
Description : In patients of bronchial asthma inhaled corticosteroids achieve the following except: A. Reduce the need for bronchodilator medication B. Control an attack of refractory asthma C. Reduce bronchial hyperreactivity D. Reverse diminished responsiveness to sympathomimetic bronchodilators
Last Answer : B. Control an attack of refractory asthma
Description : Intranasal spray of budesonide is indicated in: A. Common cold B. Acute sinusitis C. Perennial vasomotor rhinitis D. Epistaxis
Last Answer : C. Perennial vasomotor rhinitis
Description : Systemic corticosteroids are indicated in the following conditions except: A. Mild episodic asthma B. Severe chronic asthma C. Status asthmaticus D. To prevent neonatal respiratory distress syndrome
Last Answer : A. Mild episodic asthma
Description : The most consistent, pronounced and sustained relief of symptoms in chronic bronchial asthma is afforded by: A. β2 sympathomimetics B. Anticholinergics C. Sodium cromoglycate D. Corticosteroids
Last Answer : D. Corticosteroids
Description : In comparison to inhaled β 2 adrenergic agonists, the inhaled anticholinergics: A. Are more effective in bronchial asthma B. Are better suited for control of an acute attack of asthma C. Produce slower response in bronchial asthma D. Produce little benefit in chronic obstructive lung disease
Last Answer : C. Produce slower response in bronchial asthma
Description : Montelukast produces the following action(s) in bronchial asthma patients: A. Bronchodilatation B. Suppression of bronchial hyperreactivity C. Stabilization of mast cells D. Both 'A' and 'B'
Last Answer : D. Both 'A' and 'B'
Description : Which of the following β 2 agonist bronchodilators is given by inhalation, and is suitable for both terminating asthma attacks as well as for twice daily prophylaxis: A. Terbutaline B. Bambuterol C. Salmeterol D. Formoterol
Last Answer : D. Formoterol
Description : Select the correct statement about salmeterol: A. It is a long acting selective β2 agonist bronchodilator B. It is a bronchodilator with anti-inflammatory property C. It is a β blocker that can be safely given to asthmatics D. It is an antihistaminic with mast cell stabilizing property
Last Answer : A. It is a long acting selective β2 agonist bronchodilator
Description : Inhaled salbutamol is useful in bronchial asthma for: A. Aborting/terminating asthma attacks B. Round the clock prophylaxis of asthma C. Status asthmaticus D. All of the above
Last Answer : A. Aborting/terminating asthma attacks
Description : Bronchodilators are useful in cough: A. Only when cough is nonproductive B. Only when cough is associated with thick sticky secretions C. Only when reflex bronchoconstriction is associated D. Irrespective of nature of cough or associated features
Last Answer : C. Only when reflex bronchoconstriction is associated
Description : Which of the following ingredients has neither specific antitussive nor expectorant nor bronchodilator action, but is commonly present in proprietary cough formulations: A. Ambroxol B. Chlorpheniramine C. Guaiphenesin D. Noscapine
Last Answer : B. Chlorpheniramine
Description : The following antitussive is present in opium but has no analgesic or addicting properties: A. Noscapine B. Codeine C. Pholcodeine D. Ethylmorphine
Last Answer : A. Noscapine
Description : Which of the following is not an antitussive: A. Oxeladin B. Clophedianol C. Dextropropoxyphene D. Dextromethorphan
Last Answer : C. Dextropropoxyphene
Description : Dextromethorphan is an: A. Analgesic B. Antitussive C. Expectorant D. Antihistaminic
Last Answer : B. Antitussive
Description : Antitussives act by: A. Liquifying bronchial secretions B. Raising the threshold of cough centre C. Reducing cough inducing impulses from the lungs D. Both ‘B’ and ‘C’ are correct
Last Answer : D. Both ‘B’ and ‘C’ are correct
Description : Mucokinetic is a drug which: A. Reduces airway mucus secretion B. Increases airway mucus secretion C. Makes respiratory secretions more watery D. Stimulates mucociliary activity of bronchial epithelium
Last Answer : C. Makes respiratory secretions more watery
Description : Codeine is used clinically as: A. Analgesic B. Antitussive C. Antidiarrhoeal D. All of the above
Last Answer : D. All of the above
Description : Bromhexine acts by: A. Inhibiting cough centre B. Irritating gastric mucosa and reflexly increasing bronchial secretion C. Depolymerizing mucopolysaccharides present in sputum. D. Desensitizing stretch receptors in the lungs
Last Answer : C. Depolymerizing mucopolysaccharides present in sputum.
Description : The following expectorant acts both directly on the airway mucosa as well as reflexly: A. Potassium iodide B. Guaiphenesin C. Terpin hydrate D. Bromhexine
Last Answer : A. Potassium iodide
Description : The characteristic feature of phenytoin pharmacokinetics is: A. High first pass metabolism B. Nonsaturation kinetics of metabolism C. Capacity limited metabolism saturating at higher therapeutic concentration range D. Extrahepatic metabolism
Last Answer : C. Capacity limited metabolism saturating at higher therapeutic concentration range
Description : The distinctive feature(s) of sparfloxacin compared to ciprofloxacin is/are: A. Enhanced activity against gram positive bacteria B. Lack of pharmacokinetic interaction with theophylline and warfarin C. Higher incidence of phototoxic reaction D. All of the above
Description : Rifampicin inhibits (A) Unwinding of DNA (B) Initiation of replication (C) Initiation of translation (D) Initiation of transcription
Last Answer : Answer : D
Description : The following drug can cause rickets in children by interfering with vitamin D action: A. Tetracycline B. Digoxin C. Phenytoin D. Ciprofloxacin
Last Answer : C. Phenytoin
Description : Relatively higher dose of theophylline is required to attain therapeutics plasma concentration in (a) Smokers (b) Congestive heart failure patients (c) Those receiving erythromycin (d) Those receiving cimetidine
Last Answer : Ans: A
Description : Relatively higher dose of theophylline is required to attain therapeutic plasma concentration in: A. Smokers B. Congestive heart failure patients C. Those receiving erythromycin D. Those receiving cimetidine
Last Answer : A. Smokers
Description : The following adverse effect(s) of phenytoin is/are related to high plasma drug concentration: A. Ataxia B. Hirsutism C. Gum hyperplasia D. All of the above
Last Answer : A. Ataxia
Description : he antiepileptic drug which suppresses maximal electroshock as well as kindled seizures, raises pentylenetetrazol threshold and is effective in both generalized tonic-clonic as well as absence seizures is: A. Phenytoin B. Carbamazepine C. Sodium valproate D. Ethosuximide
Last Answer : C. Sodium valproate
Description : When caring for a patient with an uncomplicated, mild urinary tract infection (UTI), the nurse knows that recent studies have shown which of the following drugs to be a good choice for ... to be significantly more effective than TMP-SMX in community-based patients and in nursing home residents.
Last Answer : a) Levofloxacin (Levaquin) Levofloxacin, a floroquinolone, is a good choice for short-course therapy of uncomplicated, mild to moderate UTI. Clinical trial data show high patient compliance with the 3-day regimen (95.6%) and a high eradication rate for all pathogens (96.4%).
Description : The drugs that form complexes with pyridoxal are (A) Isoniazid (B) Penicillamine (C) Rifampicin (D) Both (A) and (B)
Description : Which of the following antitubercular drugs is not hepatotoxic: A. Isoniazid B. Rifampicin C. Pyrazinamide D. Ethambutol
Last Answer : D. Ethambutol
Description : Which of the following drugs can precipitate hypoglycaemia if given to a diabetic controlled with a sulfonylurea drug: A. Phenobarbitone B. Chloramphenicol C. Rifampicin D. Oral contraceptive
Last Answer : . Chloramphenicol
Description : Ciprofloxacin inhibits the synthesis of (A) DNA in prokaryotes (B) DNA in prokaryotes and eukaryotes (C) RNA in prokaryotes (D) RNA in prokaryotes and eukaryotes
Last Answer : Answer : A
Description : Ciprofloxacin inhibits (A) DNA topisomerase II (B) DNA polymerase I (C) DNA polymerase III (D) DNA gyrase
Description : Ciprofloxacin inhibits the synthesis of (A) DNA (B) mRNA (C) tRNA (D) rRNA
Description : Select the drug that undergoes extensive first-pass metabolism in the liver: A. Phenobarbitone B. Propranolol C. Phenylbutazone D. Theophylline
Last Answer : B. Propranolol
Description : Allopurinol does not inhibit the metabolism of: A. 6-Mercaptopurine B. 6-Thioguanine C. Azathioprine D. Theophylline
Last Answer : B. 6-Thioguanine
Description : Choose the correct statement about theophylline: A. Its use in asthma has declined because of narrow safety margin B. Its dose needs to be reduced in smokers C. It acts by increasing the formation of cAMP D. Its plasma halflife is longer in children compared to that in adults
Last Answer : A. Its use in asthma has declined because of narrow safety margin
Description : The plasma protein bound fraction of a drug: A. Contributes to the response at the given moment B. Remains constant irrespective of the total drug concentration C. Remains constant irrespective of the disease state D. Is not available for metabolism unless actively extracted by the liver
Last Answer : D. Is not available for metabolism unless actively extracted by the liver
Description : Transdermal drug delivery systems offer the following advantages except: A. They produce high peak plasma concentration of the drug B. They produce smooth and nonfluctuating plasma concentration of the ... the achieved plasma drug concentration D. They avoid hepatic first-pass metabolism of the drug
Last Answer : A. They produce high peak plasma concentration of the drug
Last Answer : A