Isoxsuprine increases limb blood flow in normal individuals, but is of limited efficacy in Buerger’s disease,
because in this disease:
A. Vasodilator β adrenoceptors are deficient
B. There is loss of sympathetic innervation
C. Blood flow to the affected limb is reduced by
organic obstruction
D. The drug is not delivered to the affected site
because in this disease:
A. Vasodilator β adrenoceptors are deficient
B. There is loss of sympathetic innervation
C. Blood flow to the affected limb is reduced by
organic obstruction
D. The drug is not delivered to the affected site