Do you believe in a human soul/spirit as a separate entity from the brain?

Do you believe in a human soul/spirit as a separate entity from the brain?
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Changes to the physical makeup of the brain can also alter your personality in a very drastic way. There was this case of this one man, who was a violent thug. Then he had a stroke and it basically turned him into a polite, tame, docile kitten. That is clear cut evidence that the “soul” is in no way separate from the brain.
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