Description : Over the centuries, the palace, devastated by earthquakes and fires, almost disappeared (,) and what remained of it, .... Over the centuries, the palace almost disappeared, devastated by earthquakes and ... problematic comma is in parentheses and I think it should only be there in the second case)
Last Answer : Somehow no one is involved, so ... The comma belongs in both cases because: PS This is a consequential ratio, - due to earthquakes and fires, "..and what's left of it". (From the original palace today a ruin, ruins, just the rest of the magnificent building, etc.)