Contrast and compare competitive inhibitors with noncompetitive inhibitors. Which can be overcome by the addition of more substrate?

1 Answer

Answer :

Competitive inhibitors reduce the productivity of enzymes by blocking substrates from entering active sites. This inhibition is what can be overcome by the addition of more substrate. Noncompetitive inhibitors, unlike competitive ones, don’t directly compete with substrate to bind to the enzyme at the active site. So active site will become less and less effective at helping convert substrate to product.

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