Description : The beta lactam antibiotics include the following: A. Cephalosporins B. Monobactams C. Carbapenems D. All of the above
Last Answer : D. All of the above
Description : Antibacterial agents can be classified with regard to their structure, mechanism of action, and activity pattern against various types of bacterial pathogens. Which of the following ... are both bacteriostatic d. Sulfonamides and trimethoprim act synergistically to inhibit purine synthesis
Last Answer : Answer: a, b, d Penicillins, cephalosporins, and monobactams possess a b-lactam ring of some type and act to bind bacterial division plate proteins, thus inhibiting cell wall ... act in different mechanisms to inhibit protein synthesis, therefore two agents in combination act synergistically
Description : Drug destroying type of bacterial resistance is important for the following antibiotics except: A. Cephalosporins B. Tetracyclines C. Chloramphenicol D. Aminoglycosides
Last Answer : B. Tetracyclines
Description : The sulfonamides interfere with bacterial metabolism by a. blocking cell wall synthesis. b. disrupting folic acid metabolism. c. reacting with bacterial cell membranes. d. inhibiting DNA replication.
Last Answer : b. disrupting folic acid metabolism.
Description : Antibiotics inhibiting nucleic acid synthesis include a. Rifampin and quinolones. b. Aminoglycosides and tetracyclines. c. Lincosamides and streptogramins. d. Macrolides and ami noglycosides.
Last Answer : a. Rifampin and quinolones.
Description : Two drugs that affect cell wall synthesis are a. Erythromycin and penicillin. b. Vancomycin and cephalosporin. c. Tetracycline and polymyxin b. d. Chloramphenicol and streptomycin.
Last Answer : a. Erythromycin and penicillin.
Description : Isoniazid has a very narrow drug spectrum as the active form of the drug specifically interferes with cell wall synthesis in _____ by inhibiting the production of mycolic acid in the cell wall. a. Staphylococcus b. Streptococcus c. Enterococcus d. Mycobacterium
Last Answer : d. Mycobacterium
Description : Tetracyclines interfere with a. Translation. b. Transcription. c. Dna Replication. d. Membrane Function.
Last Answer : a. Translation.
Description : Antifungal drugs, such as_ __, inhibit proper formation of a. Miconazole; A Plasma Membrane b. Griseofulvin; Dna c. Ketoconazole; A Cell Wall d. Tiucytosine; A Rnicrotubule
Last Answer : d. Tiucytosine; A Rnicrotubule
Description : Vancomycin inhibits _____________ synthesis. a. protein b. DNA c. bacterial cell wall d. RNA
Last Answer : c. bacterial cell wall
Description : Trimethoprim and sulfamethoxazole are examples of synthesis. a. Sulfonamides; PABA b. Penicillins; Cell Wall c. Sulfonamides; Folic Acid d. Macrolides; Protein
Last Answer : c. Sulfonamides; Folic Acid
Description : . All of the following antiprotozoal drugs have been used to treat malaria except: a. Melarsoprol. b. Quinine. c. Mefloquine. d. Chloroquine.
Last Answer : a. Melarsoprol.
Description : Tetracyclines are still the first choice drugs for the following disease. (a) Granuloma linguinale (b) Chancroid (c) Syphilis (d) Gonorrhoea in patients allergic to penicillin
Last Answer : Ans: A
Description : Stevens Johnson sjmdrome is the most common adverse effect associated with one of the following category of drugs : (A) Sulphonamides (B) Macrolides (C) Penicillins (D) Tetracyclines
Last Answer : (A) Sulphonamides
Description : ]Tetracyclines are still the first choice drugs for the following disease: A. Granuloma inguinale B. Chancroid C. Syphilis D. Gonorrhoea in patients allergic to penicillin
Last Answer : A. Granuloma inguinale
Description : Interaction between the following pair of drugs can be avoided by making suitable adjustments: A. Levodopa and metoclopramide B. Furosemide and indomethacin C. Tetracyclines and ferrous sulfate D. Clonidine and chlorpromazine
Last Answer : C. Tetracyclines and ferrous sulfate
Description : The following statement is not correct for uremic patients: A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened B. Pethidine can cause seizures C. Diazepam produces exaggerated CNS depression D. Tetracyclines further raise blood urea level
Last Answer : A. Attainment of steady-state plasma concentration of drugs eliminated through the kidney is hastened
Description : Select the class of antibiotics which act by interfering with bacterial protein synthesis, but are bactericidal: A. Tetracyclines B. Aminoglycosides C. Macrolides D. Lincosamides
Last Answer : B. Aminoglycosides
Description : Olanzapine has the following features except: A. It is an antipsychotic drug with weak D2 receptor blocking action B. It has potent 5-HT2 blocking and antimuscarinic actions C. It lowers seizure threshold D. It produces prominent extrapyramidal side effects
Last Answer : D. It produces prominent extrapyramidal side effect
Description : Desensitization therapy can involve a. The use of blocking antibodies. b. Injections of small amounts of allergen. c. Allergen injections of several months. d. All the above (A—C) are correct.
Last Answer : d. All the above (A—C) are correct.
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because (a) It is completely absorbed in the small intestines so that drug concentration in the colonic ... (d) It is a potent tetracycline and inhibits the superinfection causing microbes as well
Description : Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because: A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents ... the microbes of the normal gut flora D. It is a potent tetracycline and inhibits
Last Answer : A. It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low
Description : Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of ... protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor
Last Answer : Answer: a, d Although most hormone and other messenger receptors are extracellular, intracellular receptors have been identified. The hormone messengers involved for these receptors are primarily ... DNA-binding domain of the receptor. Activation involves the dissociation of the inhibitor protein
Description : Regarding the antibacterial action of gentamicin, which one of the following statements is most accurate? (a) Efficacy is directly proportionate to the time that the plasma level of the drug is ... an inhibitor of cell wall synthesis (e) The antibacterial action of gentamicin is time - dependent
Last Answer : Ans: C
Description : Where does protein synthesis take place in all cells? a. mitochondria b. cell membranes c. ribosomes d. Golgi apparatus
Last Answer : c. ribosomes
Description : The use of prophylactic antibiotics has become commonplace. Which of the following statement(s) is/are true concerning the prophylactic use of antibiotics? a. The appropriate use of prophylactic ... d. The topical use of antimicrobial agents is of no advantage in the prophylactic setting
Last Answer : Answer: a Intravenous administration of an antibiotic is clearly indicated for patients undergoing clean contaminated operations. These antibiotics should be administered prior to surgery ... of antimicrobial agents is equivalent to the administration of intravenous antimicrobial agent antibiotics
Description : The third generation cephalosporins differ from the first generation cephalosporins in that they are: A. More active against gram positive cocci B. More active against gram negative enterobacteriaceae C. Nonimmunogenic D. Not excreted by tubular secretion
Last Answer : B. More active against gram negative enterobacteriaceae
Description : Nonsteroidal antiinflammatory drugs reduce the diuretic action of furosemide by: A. Preventing prostaglandin mediated intrarenal haemodynamic actions B. Blocking the action in ascending limb of loop ... C. Enhancing salt and water reabsorption in distal tubule D. Increasing aldosterone secretion
Last Answer : A. Preventing prostaglandin mediated intrarenal haemodynamic actions
Description : Choose the correct statement about long acting calcium channel blocking drugs as antihypertensives: A. They are the most effective drugs in suppressing hypertensive left ventricular hypertrophy B. They ... more than β blockers D. They have no beneficial effect in hypertensive/diabetic nephropath
Last Answer : B. They are as effective as diuretics or β blockers in reducing cardiovascular/total mortality
Description : Compared to other antipsychotic drugs, the distinctive feature of penfluridol is: A. Very long duration of action B. Weak dopamine D2 blocking activity C. Lack of extrapyramidal side effects D. Additional 5-HT2 receptor blocking activity
Last Answer : A. Very long duration of action
Description : Neuromuscular blocking drugs do not produce central actions because: A. They do not cross the blood-brain barrier B. Nicotinic receptors are not present in the brain C. They are sequestrated in the periphery by tight binding to the skeletal muscles D. They do not ionise at the brain pH
Last Answer : A. They do not cross the blood-brain barrier
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve
Last Answer : C. Do not block any effect of injected adrenaline
Description : Ganglion blocking drugs are no longer used in therapeutics because: A. They have few and weak pharmacological actions B. They produce many side effects C. They are inactive by oral route D. They have short duration of action
Last Answer : A. They have potent antiovulatory action of their own
Description : Adrenergic neurone blocking drugs: A. Block the action of adrenaline on neuronal α2 adrenoceptors B. Block both α and β adrenoceptor mediated effects of injected adrenaline C. Do not block any effect of injected adrenaline D. Do not block the effects of sympathetic nerve stimulation
Last Answer : B. They produce many side effects
Description : Bacillus subtilis makes a good "bacterial factory" in genetic engineering because _____. a. it normally retains the products it makes b. it is not a human pathogen c. contains endotoxins in it's cell wall d. traditionally ferments sugars
Last Answer : b. it is not a human pathogen
Description : Which one of the following is NOT true of exotoxins? a. They are proteins. b. They are part of cell wall structure. c. They are released from live bacterial cells. d. They trigger antibody production.
Last Answer : d. They trigger antibody production.
Description : Which one of the following is true of the hypha? a. It is the morphological unit of the fungus. b. It is visible without a microscope. c. It lacks a cell wall. d. None of the above (A-C) is true.
Last Answer : a. It is the morphological unit of the fungus.
Description : Which of the following characteristics would not be used to classify viruses? A.Type of cell wall structure B.Type of nucleic acid C.Presence of an envelope D.Symmetry
Last Answer : A.Type of cell wall structure
Description : Which of the following statements is not true regarding Mycobacterium tuberculosis and/or the disease it causes? A.The pathogen contains mycolic acid in its cell wall B.The pathogen can live inside macrophages C.Antibodies to the pathogen are protective D.None of these
Last Answer : C.Antibodies to the pathogen are protective
Description : The cell wall of A.gram-positive bacteria are thicker than gram-negative bacteria B.gram-negative bacteria are thicker than gram-positive bacteria C.both have same thickness but composition is different D.none of these
Last Answer : A.gram-positive bacteria are thicker than gram-negative bacteria
Description : Which of the following is not true for prokaryotic organism? A.Nucleus is not bounded by nuclear membrane B.Chromosomes does not contain histones C.80S ribosomes are distributed in cytoplasm D.Cell wall contains peptidoglycan as one of the major component
Last Answer : C.80S ribosomes are distributed in cytoplasm
Description : Cell wall protein of Streptococcus pyogenescrossreactswith human A- synovial fluid B- cardiac valves C- myocardium D- vascular intima
Last Answer : myocardium
Description : Which of the following is true about cell wall of gram-positive bacteria? A- It consists of multiple layers B- It is thicker than that associated with gram-negative bacteria C- It contains teichoic acids D- D.All of these
Last Answer : D.All of these
Description : Cyanobacteria have A-a gram-positive cell wall B- a gram-negative cell wall C- Neither (a) nor (b) D-No cell wall
Last Answer : a gram-negative cell wall
Description : The cell wall of A- gram-positive bacteria are thicker than gram-negative bacteria B- gram-negative bacteria are thicker than gram-positive bacteria C- both have same thickness but composition is different D- none of these
Last Answer : gram-positive bacteria are thicker than gram-negative bacteria
Description : Which of the following is true about cell wall of gram-positive bacteria? A-It consists of multiple layers B- It is thicker than that associated with gram-negative bacteria C- It contains teichoic acids D- All of these
Last Answer : All of these