Which of the following step of translation does not consume a high energy phosphate bond? (a) Peptidyl transferase reaction (b) Aminoacyl tRNA binding to A-site (c) Translocation (d) Amino acid activation

Which of the following step of translation does not
consume a high energy phosphate bond?
(a) Peptidyl transferase reaction
(b) Aminoacyl tRNA binding to A-site
(c) Translocation
(d) Amino acid activation
by

1 Answer

Answer :

(a) Peptidyl transferase reaction
by

Related questions

Which of the following step of translation does not consume a high energy phosphate bond? (a) Peptidyl transferase reaction (b) Aminoacyl tRNA binding to A-site (c) Translocation (d) Amino acid activation

Description : Which of the following step of translation does not consume a high energy phosphate bond? (a) Peptidyl transferase reaction (b) Aminoacyl tRNA binding to A-site (c) Translocation (d) Amino acid activation

Last Answer : (b) Aminoacyl tRNA binding to A-site

Erythromycin acts on ribosomes and inhibit (A) Formation of initiation complex (B) Binding of aminoacyl tRNA (C) Peptidyl transferase activity (D) Translocation

Description : Erythromycin acts on ribosomes and inhibit (A) Formation of initiation complex (B) Binding of aminoacyl tRNA (C) Peptidyl transferase activity (D) Translocation

Last Answer : Answer : D

Erythromycin binds to 50 S ribosomal sub unit and (A) Inhibits binding of amino acyl tRNA (B) Inhibits Peptidyl transferase activity (C) Inhibits translocation (D) Causes premature chain termination

Description : Erythromycin binds to 50 S ribosomal sub unit and (A) Inhibits binding of amino acyl tRNA (B) Inhibits Peptidyl transferase activity (C) Inhibits translocation (D) Causes premature chain termination

Last Answer : Answer : C

Which binding is inhibited by pactamycin? A- Aminoacyl-tRNA to the A-site of 30S subunit B- Initiator-tRNA to 30S/40S initiation complexes C- Peptidyl t-RNA to the 50S subunit D- Formation of peptide bond in P site

Description : Which binding is inhibited by pactamycin? A- Aminoacyl-tRNA to the A-site of 30S subunit B- Initiator-tRNA to 30S/40S initiation complexes C- Peptidyl t-RNA to the 50S subunit D- Formation of peptide bond in P site

Last Answer : Initiator-tRNA to 30S/40S initiation complexes

Translocation of the newly formed peptidyl tRNA at the A site into the empty P site involves (A) EF-II, GTP (B) EF-I, GTP (C) EF-I, GDP (D) Peptidyl transferase, GTP

Description : Translocation of the newly formed peptidyl tRNA at the A site into the empty P site involves (A) EF-II, GTP (B) EF-I, GTP (C) EF-I, GDP (D) Peptidyl transferase, GTP

Last Answer : Answer : A

The mechanism of antibacterial action of tetracycline involves (a) Binding to a component of the 50S ribosomal subunit (b) Inhibition of translocase activity (c) Blockade of binding of aminoacyl – tRNA to bacterial ribosomes (d) Selective inhibition of ribosomal peptidyl transferases (e) Inhibition of DNA–dependent RNA polymerase

Description : The mechanism of antibacterial action of tetracycline involves (a) Binding to a component of the 50S ribosomal subunit (b) Inhibition of translocase activity (c) Blockade of binding of ... (d) Selective inhibition of ribosomal peptidyl transferases (e) Inhibition of DNA-dependent RNA polymerase

Last Answer : Ans: C

The α-amino group of the new amino acyl tRNA in the A site carries out a nucleophilic attack on the esterified carboxyl group of the peptidyl tRNA occupying the P site. This reaction is catalysed by (A) DNA polymerase (B) RNA polymerase (C) Peptidyl transferase (D) DNA ligase

Description : The α-amino group of the new amino acyl tRNA in the A site carries out a nucleophilic attack on the esterified carboxyl group of the peptidyl tRNA occupying the P site. This reaction is catalysed by (A) DNA polymerase (B) RNA polymerase (C) Peptidyl transferase (D) DNA ligase

Last Answer : Answer : C

What is the action of tetracycline in prokaryotes? A- It blocks translocation reaction on ribosomes B- It blocks peptidyltransferase reaction on ribosomes C- It blocks the binding of amino-acyl tRNA to the A site of ribosomes D- Not known with certainity

Description : What is the action of tetracycline in prokaryotes? A- It blocks translocation reaction on ribosomes B- It blocks peptidyltransferase reaction on ribosomes C- It blocks the binding of amino-acyl tRNA to the A site of ribosomes D- Not known with certainity

Last Answer : It blocks the binding of amino-acyl tRNA to the A site of ribosomes

What is the action of tetracycline in prokaryotes? A- It blocks translocation reaction on ribosomes B- It blocks peptidyltransferase reaction on ribosomes C- It blocks the binding of amino-acyl tRNA to the A site of ribosomes D- Not known with certainity

Description : What is the action of tetracycline in prokaryotes? A- It blocks translocation reaction on ribosomes B- It blocks peptidyltransferase reaction on ribosomes C- It blocks the binding of amino-acyl tRNA to the A site of ribosomes D- Not known with certainity

Last Answer : It blocks the binding of amino-acyl tRNA to the A site of ribosomes

Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA

Description : Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA

Last Answer : Answer : A

Peptidyl transferase activity is present in (A) 40 S ribosomal subunit (B) 60 S ribosomal subunit (C) eEF-2 (D) Amino acyl tRNA

Description : Peptidyl transferase activity is present in (A) 40 S ribosomal subunit (B) 60 S ribosomal subunit (C) eEF-2 (D) Amino acyl tRNA

Last Answer : Answer : B

Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to 50S ribosome and blocking translocation of peptide chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

Description : Chloramphenicol inhibits bacterial protein synthesis by: A. Binding to 30S ribosome and inhibiting attachment of aminoacyl tRNA B. Binding to 50S ribosome and preventing peptide bond formation C. Binding to ... chain D. Binding to both 30S and 50S ribosome and inducing misreading of mRNA code

Last Answer : B. Binding to 50S ribosome and preventing peptide bond formation

Streptomycin prevents synthesis of polypeptide by (A) Inhibiting initiation process (B) Releasing premature polypeptide (C) Inhibiting peptidyl transferase activity (D) Inhibiting translocation

Description : Streptomycin prevents synthesis of polypeptide by (A) Inhibiting initiation process (B) Releasing premature polypeptide (C) Inhibiting peptidyl transferase activity (D) Inhibiting translocation

Last Answer : Answer : A

The nucleophilic attack on the esterified carboxyl group of the peptidyl-tRNA occupying the P site and the α-amino group of the new amino acyl tRNA, the number of ATP required by the amino acid on the charged tRNA is (A) Zero (B) One (C) Two (D) Four

Description : The nucleophilic attack on the esterified carboxyl group of the peptidyl-tRNA occupying the P site and the α-amino group of the new amino acyl tRNA, the number of ATP required by the amino acid on the charged tRNA is (A) Zero (B) One (C) Two (D) Four

Last Answer : Answer : A

Peptidyl transferase activity is located in (A) Elongation factor (B) A charged tRNA molecule (C) Ribosomal protein (D) A soluble cytosolic protein

Description : Peptidyl transferase activity is located in (A) Elongation factor (B) A charged tRNA molecule (C) Ribosomal protein (D) A soluble cytosolic protein

Last Answer : Answer : C

Which of the following statement(s) is/are true concerning translation of the mRNA message to protein synthesis? a. An adaptor molecule, tRNA, recognizes specific nucleic acid bases and unites them with specific amino acids b. Covalent attachment of tRNA to amino acids is energy dependent c. The formation of a peptide bond between the growing peptide chain and the free amino acid occurs in the free cytoplasm d. Complete protein synthesis takes hours

Description : Which of the following statement(s) is/are true concerning translation of the mRNA message to protein synthesis? a. An adaptor molecule, tRNA, recognizes specific nucleic acid bases and unites them ... and the free amino acid occurs in the free cytoplasm d. Complete protein synthesis takes hours

Last Answer : Answer: a, b The synthesis of protein involves conversion from a four-letter nucleotide language to one of 20 chemically distinct amino acids. This process is referred to as ... translation and be moving down the mRNA molecules simultaneously, thus increasing the rate of protein synthesis

How many high-energy phosphate bond equivalents are required for amino acid activation in protein synthesis? (A) One (B) Two (C) Three (D) Four

Description : How many high-energy phosphate bond equivalents are required for amino acid activation in protein synthesis? (A) One (B) Two (C) Three (D) Four

Last Answer : Answer : B

Tetracylin prevents synthesis of polypeptide by (A) Blocking mRNA formation from DNA (B) Releasing peptides from mRNA-tRNA complex (C) Competing with mRNA for ribosomal binding sites (D) Preventing binding of aminoacyl tRNA

Description : Tetracylin prevents synthesis of polypeptide by (A) Blocking mRNA formation from DNA (B) Releasing peptides from mRNA-tRNA complex (C) Competing with mRNA for ribosomal binding sites (D) Preventing binding of aminoacyl tRNA

Last Answer : Answer : D

In the process of activation of amino acids for protein synthesis, the number of high energy phosphate bond equivalent utilised is (A) 0 (B) 1 (C) 2 (D) 4

Description : In the process of activation of amino acids for protein synthesis, the number of high energy phosphate bond equivalent utilised is (A) 0 (B) 1 (C) 2 (D) 4

Last Answer : Answer : C

After formation of a peptide bond, mRNA is translocated along the ribosome by (A) eEF-1 and GTP (B) eEF-2 and GTP (C) Peptidyl transferase and GTP (D) Peptidyl transferase and ATP

Description : After formation of a peptide bond, mRNA is translocated along the ribosome by (A) eEF-1 and GTP (B) eEF-2 and GTP (C) Peptidyl transferase and GTP (D) Peptidyl transferase and ATP

Last Answer : Answer : B

The enzyme amino acyl tRNA synthetase is involved in (A) Dissociation of discharged tRNA from 80S ribosome (B) Charging of tRNA with specific amino acids (C) Termination of protein synthesis (D) Nucleophilic attack on esterified carboxyl group of peptidyl tRNA

Description : The enzyme amino acyl tRNA synthetase is involved in (A) Dissociation of discharged tRNA from 80S ribosome (B) Charging of tRNA with specific amino acids (C) Termination of protein synthesis (D) Nucleophilic attack on esterified carboxyl group of peptidyl tRNA

Last Answer : Answer : B

Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ribosome does not move along the mRNA and the peptide chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin

Description : Select the antibiotic which inhibits bacterial protein synthesis by interfering with translocation of elongating peptide chain from acceptor site back to the peptidyl site of the ribosome so that ... chain is prematurely terminated: A. Chloramphenicol B. Erythromycin C. Tetracycline D. Streptomycin

Last Answer : B. Erythromycin

Which of the following molecule catalyzes the transpeptidation reaction? A.RNA polymerase B.Peptidyl transferase C.DNA ligase D.DNA polymerase

Description : Which of the following molecule catalyzes the transpeptidation reaction? A.RNA polymerase B.Peptidyl transferase C.DNA ligase D.DNA polymerase

Last Answer : B.Peptidyl transferase

In the process of elongation of chain binding of amino acyl tRNA to the A site requires (A) A proper codon recognition (B) GTP (C) EF-II (D) GDP

Description : In the process of elongation of chain binding of amino acyl tRNA to the A site requires (A) A proper codon recognition (B) GTP (C) EF-II (D) GDP

Last Answer : Answer : A

During amino acid activation a(n) A-amino acid is bound to tRNA B- amino acid is bound to mRNA C-methyl group is attached to rRNA D-methyl group is attached to an amino acid

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Last Answer : amino acid is bound to tRNA

During amino acid activation a(n) A-amino acid is bound to tRNA B- amino acid is bound to mRNA C-methyl group is attached to rRNA D-methyl group is attached to an amino acid

Description : During amino acid activation a(n) A-amino acid is bound to tRNA B- amino acid is bound to mRNA C-methyl group is attached to rRNA D-methyl group is attached to an amino acid

Last Answer : amino acid is bound to tRNA

During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Description : During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Last Answer : (c) association of 30S mRNA with formyl-met- tRNA

.The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon

Description : .The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon

Last Answer : (d) recognition of an anti-codon.

.During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Description : .During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.

Last Answer : (c) association of 30S mRNA with formyl-met- tRNA

The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon.

Description : The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon.

Last Answer : c) aminoacylation of tRNA

Peptidyl transferase activity of 50 S ribosomal subunits is inhibited by (A) Rifampicin (B) Cycloheximide (C) Chloramphenicol (D) Erythromycin

Description : Peptidyl transferase activity of 50 S ribosomal subunits is inhibited by (A) Rifampicin (B) Cycloheximide (C) Chloramphenicol (D) Erythromycin

Last Answer : Answer : C

In prokaryotes, chloramphenicol (A) Causes premature release of the polypeptide chain (B) Causes misreading of the mRNA (C) Depolymerises DNA (D) Inhibits peptidyl transferase activity

Description : In prokaryotes, chloramphenicol (A) Causes premature release of the polypeptide chain (B) Causes misreading of the mRNA (C) Depolymerises DNA (D) Inhibits peptidyl transferase activity

Last Answer : Answer : A

Peptidyl transferase a) Is a 23s rRNA b) forms peptide bonds c) component of ribosome d) all the three

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What does the following equation denote? Amino acid + ATP `rarr` Aminoacyl AMP + PP

Description : What does the following equation denote? Amino acid + ATP `rarr` Aminoacyl AMP + PP

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The first amino acyl tRNA which initiates translation in prokaryotes is (A) Mehtionyl tRNA (B) Formylmethionyl tRNA (C) Tyrosinyl tRNA (D) Alanyl tRNA

Description : The first amino acyl tRNA which initiates translation in prokaryotes is (A) Mehtionyl tRNA (B) Formylmethionyl tRNA (C) Tyrosinyl tRNA (D) Alanyl tRNA

Last Answer : Answer : B

The first amino acyl tRNA which initiates translation in eukaryotes is (A) Mehtionyl tRNA (B) Formylmethionyl tRNA (C) Tyrosinyl tRNA (D) Alanyl tRNA

Description : The first amino acyl tRNA which initiates translation in eukaryotes is (A) Mehtionyl tRNA (B) Formylmethionyl tRNA (C) Tyrosinyl tRNA (D) Alanyl tRNA

Last Answer : Answer : A

What happens at the ribosome in the production of a protein? a. mRNA brings the codon b. tRNA brings the anticodon c. the amino acids are linked by polypeptide bonds d. translation e. all the above

Description : What happens at the ribosome in the production of a protein? a. mRNA brings the codon b. tRNA brings the anticodon c. the amino acids are linked by polypeptide bonds d. translation e. all the above

Last Answer : c. the amino acids are linked by polypeptide bonds

A characteristic of protein synthesis in both the archaea and eukarya is A.transcription and translation are coupled B.translation is inhibited by diphtheria toxin C.proteins are synthesized from D-, rather than L-, isomers of amino acids D.the initiator tRNA is charged with N-formyl- methionine

Description : A characteristic of protein synthesis in both the archaea and eukarya is A.transcription and translation are coupled B.translation is inhibited by diphtheria toxin C.proteins are synthesized from D-, ... L-, isomers of amino acids D.the initiator tRNA is charged with N-formyl- methionine

Last Answer : C.proteins are synthesized from

A characteristic of protein synthesis in both the archaea and eukarya is A- transcription and translation are coupled B- translation is inhibited by diphtheria toxin C- .proteins are synthesized from D-, rather than L-, isomers of amino acids D- the initiator tRNA is charged with N-formyl-methionine

Description : A characteristic of protein synthesis in both the archaea and eukarya is A- transcription and translation are coupled B- translation is inhibited by diphtheria toxin C- .proteins are synthesized from D-, rather than L-, isomers of amino acids D- the initiator tRNA is charged with N-formyl-methionine

Last Answer : .proteins are synthesized from D-, rather than L-, isomers of amino acids

eIF-1A and eIF-3 are required (A) For binding of amino acyl tRNA to 40 S ribosomal subunit (B) For binding of mRNA to 40 S ribosomal subunit (C) For binding of 60 S subunit to 40 S subunit (D) To prevent binding of 60 S subunit to 40 S subunit

Description : eIF-1A and eIF-3 are required (A) For binding of amino acyl tRNA to 40 S ribosomal subunit (B) For binding of mRNA to 40 S ribosomal subunit (C) For binding of 60 S subunit to 40 S subunit (D) To prevent binding of 60 S subunit to 40 S subunit

Last Answer : Answer : D

The last step in synthesis of peptidoglycan is A- attachment of a peptide to muramic acid B- attaching two amino acids to form a cross-link C- attachment of a portion of peptidoglycan to a membrane lipid D- binding of penicillin to a membrane protein

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Last Answer : attaching two amino acids to form a cross-link

The excess energy of reactants in a chemical reaction required to dissociate into products is termed as the __________ energy. (A) Activation (B) Potential (C) Binding (D) Threshold

Description : The excess energy of reactants in a chemical reaction required to dissociate into products is termed as the __________ energy. (A) Activation (B) Potential (C) Binding (D) Threshold

Last Answer : (A) Activation

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Last Answer : Answer : D

The catalytic power of enzymes is due to (a) the presence of amino acids in their structures (b) their high molecular weight (c) their ability to lower the activation energy of the reaction (d) their limited solubility in water and other solvents

Description : The catalytic power of enzymes is due to (a) the presence of amino acids in their structures (b) their high molecular weight (c) their ability to lower the activation energy of the reaction (d) their limited solubility in water and other solvents

Last Answer : Ans:(c)

Galactose 1-phosphate is converted to uridine diphosphate galactose, the reaction is catalysed by the enzyme: (A) Glactokinase (B) Galactose 1-phosphate uridyl transferase (C) Uridine diphospho galactose 4-epimerase (D) UDP glucose pyrophosphorylase

Description : Galactose 1-phosphate is converted to uridine diphosphate galactose, the reaction is catalysed by the enzyme: (A) Glactokinase (B) Galactose 1-phosphate uridyl transferase (C) Uridine diphospho galactose 4-epimerase (D) UDP glucose pyrophosphorylase

Last Answer : Answer : B

Pick out the wrong statement. (A) In a multistep reaction, the slowest step is the rate determining step (B) In general, the rate of a reaction becomes triple for every 10°C rise in temperature (C) Slow chemical reactions have generally high values of activation energy (D) Molecularity of a reaction cannot be zero but the order of a reaction can be zero

Description : Pick out the wrong statement. (A) In a multistep reaction, the slowest step is the rate determining step (B) In general, the rate of a reaction becomes triple for every 10°C rise in temperature (C ... energy (D) Molecularity of a reaction cannot be zero but the order of a reaction can be zero

Last Answer : (B) In general, the rate of a reaction becomes triple for every 10°C rise in temperature

All the following statements about charging of tRNA are correct except (A) It is catalysed by amino acyl tRNA synthetase (B) ATP is converted into ADP and Pi in this reaction (C) The enzyme recognizes the tRNA and the amino acid (D) There is a separate enzyme for each tRNA

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Last Answer : Answer : B

The process of transfer of genetic information from DNA to RNA/formation of RNA from DNA is (a) transversion (b) transcription (c) translation (d) translocation.

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Last Answer : (c) translation

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Last Answer : transcription

Pick out the correct statement. (A) A lower temperature favours the reaction of lower activation energy (B) The dispersion number for a reactor/vessel is uL/D (C) The rate controlling step in a reaction involving many steps is the fastest step (D) Pore volume and porosity of a catalyst is measured by Brunauer￾Emmett-Teller (BET) technique

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Last Answer : (A) A lower temperature favours the reaction of lower activation energy