Description : The first amino acyl tRNA which initiates translation in prokaryotes is (A) Mehtionyl tRNA (B) Formylmethionyl tRNA (C) Tyrosinyl tRNA (D) Alanyl tRNA
Last Answer : Answer : B
Description : All of the following statements about puromycin are true except (A) It is an alanyl tRNA analogue (B) It causes premature termination of protein synthesis (C) It inhibits protein synthesis in prokaryotes (D) It inhibits protein synthesis in eukaryotes
Last Answer : Answer : A
Description : The first amino acyl tRNA approaches 40 S ribosomal subunit in association with (A) eIF-1A and GTP (B) eIF-2 and GTP (C) eIF-2C and GTP (D) eIF-3 and GTP
Description : The antibiotic which has a structure similar to the amino acyl end of tRNA tyrosine is (A) Actinomycin d (B) Streptomycin (C) Puromycin (D) Mitomycin c
Last Answer : Answer : C
Description : Erythromycin binds to 50 S ribosomal sub unit and (A) Inhibits binding of amino acyl tRNA (B) Inhibits Peptidyl transferase activity (C) Inhibits translocation (D) Causes premature chain termination
Description : Peptidyl transferase activity is present in (A) 40 S ribosomal subunit (B) 60 S ribosomal subunit (C) eEF-2 (D) Amino acyl tRNA
Description : eIF-1A and eIF-3 are required (A) For binding of amino acyl tRNA to 40 S ribosomal subunit (B) For binding of mRNA to 40 S ribosomal subunit (C) For binding of 60 S subunit to 40 S subunit (D) To prevent binding of 60 S subunit to 40 S subunit
Last Answer : Answer : D
Description : Eukaryotic initiation factors 4A, 4B and 4F bind to (A) 40 S ribosomal subunit (B) 60 S ribosomal subunit (C) mRNA (D) Amino acyl tRNA
Description : All the following statements about charging of tRNA are correct except (A) It is catalysed by amino acyl tRNA synthetase (B) ATP is converted into ADP and Pi in this reaction (C) The enzyme recognizes the tRNA and the amino acid (D) There is a separate enzyme for each tRNA
Description : The nucleophilic attack on the esterified carboxyl group of the peptidyl-tRNA occupying the P site and the α-amino group of the new amino acyl tRNA, the number of ATP required by the amino acid on the charged tRNA is (A) Zero (B) One (C) Two (D) Four
Description : The α-amino group of the new amino acyl tRNA in the A site carries out a nucleophilic attack on the esterified carboxyl group of the peptidyl tRNA occupying the P site. This reaction is catalysed by (A) DNA polymerase (B) RNA polymerase (C) Peptidyl transferase (D) DNA ligase
Description : The newly entering amino acyl tRNA into A site requires (A) EF-II (B) Ribosomal RNA (C) mRNA (D) EF-I
Description : In the process of elongation of chain binding of amino acyl tRNA to the A site requires (A) A proper codon recognition (B) GTP (C) EF-II (D) GDP
Description : The enzyme amino acyl tRNA synthetase is involved in (A) Dissociation of discharged tRNA from 80S ribosome (B) Charging of tRNA with specific amino acids (C) Termination of protein synthesis (D) Nucleophilic attack on esterified carboxyl group of peptidyl tRNA
Description : What is the action of tetracycline in prokaryotes? A- It blocks translocation reaction on ribosomes B- It blocks peptidyltransferase reaction on ribosomes C- It blocks the binding of amino-acyl tRNA to the A site of ribosomes D- Not known with certainity
Last Answer : It blocks the binding of amino-acyl tRNA to the A site of ribosomes
Description : Which of the following statement(s) is/are true concerning translation of the mRNA message to protein synthesis? a. An adaptor molecule, tRNA, recognizes specific nucleic acid bases and unites them ... and the free amino acid occurs in the free cytoplasm d. Complete protein synthesis takes hours
Last Answer : Answer: a, b The synthesis of protein involves conversion from a four-letter nucleotide language to one of 20 chemically distinct amino acids. This process is referred to as ... translation and be moving down the mRNA molecules simultaneously, thus increasing the rate of protein synthesis
Description : Which of the following step of translation does not consume a high energy phosphate bond? (a) Peptidyl transferase reaction (b) Aminoacyl tRNA binding to A-site (c) Translocation (d) Amino acid activation
Last Answer : (b) Aminoacyl tRNA binding to A-site
Last Answer : (a) Peptidyl transferase reaction
Description : What happens at the ribosome in the production of a protein? a. mRNA brings the codon b. tRNA brings the anticodon c. the amino acids are linked by polypeptide bonds d. translation e. all the above
Last Answer : c. the amino acids are linked by polypeptide bonds
Description : A characteristic of protein synthesis in both the archaea and eukarya is A.transcription and translation are coupled B.translation is inhibited by diphtheria toxin C.proteins are synthesized from D-, ... L-, isomers of amino acids D.the initiator tRNA is charged with N-formyl- methionine
Last Answer : C.proteins are synthesized from
Description : A characteristic of protein synthesis in both the archaea and eukarya is A- transcription and translation are coupled B- translation is inhibited by diphtheria toxin C- .proteins are synthesized from D-, rather than L-, isomers of amino acids D- the initiator tRNA is charged with N-formyl-methionine
Last Answer : .proteins are synthesized from D-, rather than L-, isomers of amino acids
Description : Translation results in the formation of (A) mRNA (B) tRNA (C) rRNA (D) A protein molecule
Description : In eukaryotic cells (A) Formylated tRNA is important for initiation of translation (B) Cyclohexamide blocks elongation during translation (C) Cytosolic ribosomes are smaller than those found in prokaryotes (D) Erythromycin inhibits elongation during translation
Description : Translation results in a product known as (A) Protein (B) tRNA (C) mRNA (D) rRNA
Description : In RNA moleule ‘Caps’ (A) Allow tRNA to be processed (B) Are unique to eukaryotic mRNA (C) Occur at the 3’ end of tRNA (D) Allow correct translation of prokaryotic mRNA
Description : Tetracyclines inhibit binding of amino acyl tRNAs to (A) 30 S ribosomal subunits (B) 40 S ribosomal subunits (C) 50 S ribosomal subunits (D) 60 S ribosomal subunits
Description : ATP is required for (A) Fusion of 40S and 60S of ribosome (B) Accommodation tRNA amino acid in a site of ribosome (C) Movement of ribosome along mRNA (D) formation of tRNA amino acid complex
Description : GTP is not required for (A) Capping L of mRNA (B) Fusion of 40S and 60S of ribosome (C) Accommodation of tRNA amino acid (D) Formation of tRNA amino acid complex
Description : All the following statements about recognition of a codon on mRNA by an anticodon on tRNA are correct except (A) The recognition of the third base of the codon is not very precise (B) ... degeneracy of the genetic code (D) Wobble results in incorporation of incorrect amino acids in the protein
Description : All the following statements about tRNA are correct except (A) A given tRNA can be charged with only one particular amino acid (B) The amino acid is recognized by the anticodon of tRNA (C) The amino acid is attached to end of tRNA (D) The anticodon of tRNA finds the complementary codon on mRNA
Description : Amino acid is attached to tRNA at (A) 5’-End (B) 3’-End (C) Anticodon (D) DHU loop
Description : Initiation of protein synthesis begins with binding of (A) 40S ribosomal unit on mRNA (B) 60S ribosomal unit (C) Charging of tRNA with specific amino acid (D) Attachment of aminoacyl tRNA on mRNA
Description : Degeneracy of genetic code implies that (A) Codons do not code for specific amino acid (B) Multiple codons must decode the same amino acids (C) No anticodon on tRNA molecule (D) Specific codon decodes many amino acids
Description : .The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon
Last Answer : (d) recognition of an anti-codon.
Description : The first phase of translation is (a) binding of mRNA to ribosome (b) recognition of DNA molecule (c) aminoacylation of tRNA (d) recognition of an anti-codon.
Last Answer : c) aminoacylation of tRNA
Description : what is the role of trna during translation?
Last Answer : It links the correct amino acids together
Description : Which one of the following is wrongly matched? (a) Transcription - Writing information from DNA to tRNA. (b) Translation - Using information in mRNA to make protein. (c) Repressor protein - Binds to operator to stop enzyme synthesis. (d) Operon - Structural genes, operator and promoter.
Last Answer : (c) Repressor protein - Binds to operator to stop enzyme synthesis.
Description : During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.
Last Answer : (c) association of 30S mRNA with formyl-met- tRNA
Last Answer : (d) Operon - Structural genes, operator and promoter
Description : .During translation initiation in prokaryotes, a GTP molecule is needed in (a) formation of formyl-met-tRNA (b) binding of 30S subunit of ribosome with mRNA (c) association of 30S mRNA with formyl-met- tRNA (d) association of 50S subunit of ribosome with initiation complex.
Description : Insertion of a base in a gene can cause (A) Change in reading frame (B) Garbled amino acid sequence in the encoded protein (C) Premature termination of translation (D) All of these
Description : Which of the following sequences has helped in identifying eukaryotes, eubacteria and A- Signature sequence B- Signal sequence C- Shine-Dalgarno sequence D- Amino acid sequence
Last Answer : Signature sequence
Description : Which of the following sequences has helped in identifying eukaryotes, eubacteria and archeabacterial cell types? A- Signature sequence B- Signal sequence C- Shine-Dalgarno sequence D- Amino acid sequence
Description : The RNA that pick up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis is called (a) rRNA (b) RNA (c) mRNA (d) tRNA.
Last Answer : a) rRNA
Description : Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.
Last Answer : (b) tRNA
Description : The RNA that pick up specific amino acid from amino acid pool in the cytoplasm to ribosome during protein synthesis is called (a) rRNA (b) RNA (c) mRNA (d) tRNA
Last Answer : tRNA
Description : .Amino acid sequence, in protein synthesis is decided by the sequence of (a) rRNA (b) tRNA (c) mRNA (d) cDNA.
Last Answer : (c) mRNA
Description : Site in the ribosome from which the tRNA donates amino acids to the growing polypeptide chain is A- P site B- O site C- T site D- A site
Last Answer : P site
Description : During amino acid activation a(n) A-amino acid is bound to tRNA B- amino acid is bound to mRNA C-methyl group is attached to rRNA D-methyl group is attached to an amino acid
Last Answer : amino acid is bound to tRNA