Description : Markedly increased concentration responsible for kernicterus in hemolytic disease of the newborn. A A. Unconjugated bilirubin B. Conjugated bilirubin C. Both D. None of these
Last Answer : Unconjugated bilirubin
Description : A mixture of conjugated and unconjugated bilirubin is found in the circulation in (A) Hemolytic jaundice (B) Hepatic jaundice (C) Obstructive jaundice (D) Post hepatic jaundice
Last Answer : Answer : B
Description : Unconjugated bilirubin in serum is soluble in (A) Water (B) Alkalis (C) Acids (D) Methanal
Last Answer : Answer : D
Description : An increase in serum unconjugated bilirubin occurs in (A) Hemolytic jaundice (B) Obstructive jaundice (C) Nephritis (D) Glomerulonephritis
Last Answer : Answer : A
Description : The normal range of indirect (unconjugated) bilirubin in serum is (A) 0–0.1 mg/100 ml (B) 0.1–0.2 mg/100 ml (C) 0.2–0.7 mg/100 ml (D) 0.8–1.0 mg/100 ml
Last Answer : Answer : C
Description : All the following statements about obstructive jaundice are true except (A) Conjugated bilirubin in serum is normal (B) Total bilirubin in serum is raised (C) Bile salts are present in urine (D) Serum alkaline phosphatase is raised
Description : The normal range of direct reacting (conjugated) serum bilirubin is (A) 0–0.1 mg/100 ml (B) 0.1–0.4 mg/100 ml (C) 0.4–06 mg/100 ml (D) 0.5–1 mg/100 ml
Description : Which of the following is true of Gilbert's syndrome? 1) inheritance is autosomal recessive 2) serum conjugated bilirubin levels are elevated 3) serum bilirubin levels are decreased by fasting 4) serum bilirubin levels are decreased by liver enzyme inducers 5) there is bilirubinuria
Last Answer : Answers-4 Gilbert's syndrome is inherited in autosomal dominant fashion and affects 2-5% of the population. UDP glucuronyl transferase levels are reduced leading to an unconjugated hyperbilirubinaemia. ... the bilirubin is reabsorbed in the proximal tubule some bilirubin is detectable in the urine.
Description : One of the causes of hemolytic jaundice is (A) G-6 phosphatase deficiency (B) Increased conjugated bilirubin (C) Glucokinase deficiency (D) Phosphoglucomutase deficiency
Description : What is significance of high unconjugated bilirubin?
Last Answer : What is the answer ?
Description : Unconjugated bilirubin is derived principally from: C A. glucuronyl transferase activity B. toxic liver injury C. breakdown of senescent red blood cells D. None of these
Last Answer : breakdown of senescent red blood cells
Description : Which type of jaundice in adults is the result of increased destruction of red blood cells? a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot ... is the result of liver disease. d) Non-obstructive Non-obstructive jaundice occurs with hepatitis.
Last Answer : a) Hemolytic Hemolytic jaundice results because, although the liver is functioning normally, it cannot excrete the bilirubin as quickly as it is formed.
Description : Excretion of conjugated bilirubin from liver cells into biliary canaliculi is defective in (A) Gilbert’s disease (B) Crigler-Najjar syndrome (C) Lucey-Driscoll syndrome (D) Rotor’s syndrome
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : On average red blood cells live around 120 days. The spleen is the main organ where old red blood cells are destroyed. During the red blood cell destruction the heme groups turn into bilirubin and this substance is then captured by the liver and later excreted in the bowels as part of the bile.
Last Answer : What are the functions of the spleen?
Description : If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of (A) Serum ALT (B) Serum 5’ nucleotidase (C) Serum Pseudo cholinesterase (D) None of these
Description : Jaundice is visible when serum bilirubin exceeds (A) 0.5 mg/100 ml (B) 0.8 mg/100 ml (C) 1 mg/100 ml (D) 2.4 mg/100 ml
Description : The normal range of total serum bilirubin is (A) 0.2–1.2 mg/100 ml (B) 1.5–1.8 mg/100 ml (C) 2.0–4.0 mg/100 ml (D) Above 7.0 mg/100 ml
Description : Which one of the following tests would be most effective in ruling out the presence of active hepatocellular disease? A. Serum alanine aminotransferase (ALT) B. Serum total bilirubin C. cell surface markers D. None of these
Last Answer : Serum alanine aminotransferase (ALT)
Description : Reviewing the laboratory findings of the client, the nurse would found which findings are elevated? 1. White blood cell count 2. Total serum bilirubin 3. Alkaline phosphate 4. Red blood cell count 5. Cholesterol 6. Serum amylase A. 1, 2, and 3 B. 2, 3, and 4 C. 3, 5, and 6 D. 1, 2, and 6
Last Answer : A. 1, 2, and 3
Description : Down regulation is (A) Increased destruction of a hormone (B) Feed back inhibition of hormone secretion (C) Decreased concentration of a hormone in blood (D) Decrease in number of receptors for a hormone
Description : Which one of the following is true of IgE? 1) Is present in plasma in the same concentration as IgG 2) Is increased acutely in an asthmatic attack 3) Crosses the normal placenta 4) Is increased in the serum of atopic individuals 5) Is involved in type 2 hypersensitivity
Last Answer : Answers-4 IgG is the predominant form of immunoglobulin in plasma at a concentration around 10,000 times that of IgE. IgG crosses the placenta to confer immunity to the fetus but IgE does ... frequently increased in those with atopy but serum IgE does not rise acutely during an asthmatic attack.
Description : In hemolytic jaundice, bilirubin in urine is (A) Usually absent (B) Usually present (C) Increased very much (D) Very low
Description : In obstructive jaundice, urinary bilirubin is (A) Absent (B) Increased (C) Present (D) Present in small amount
Description : Increased urobilinogen in urine and absence of bilirubin in the urine suggests (A) Obstructive jaundice (B) Hemolytic jaundice (C) Viral hepatitis (D) Toxic jaundice
Description : Which of the following concerning the conjugation of bilirubin is correct? 1) is catalysed by a glucuronyl transferase 2) occurs in the Kupfer cells of the liver 3) is increased by valproate 4) is inhibited by rifampicin 5) is impaired in Dubin-Johnson syndrome
Last Answer : Answers-1 b - Hepatocytes. c - Enzyme inhibitor. d - Enzyme inducer. e - Conjugation is OK but excretion from the hepatocyte into the bile is impaired. (Gilbert's syndrome ... bilirubinaemia. Dubin-Johnson syndrome - bilirubin can't Depart from the hepatocyte - conjugated bilirubinaemia.)
Description : Predominantly unconjugated hyperbilirubinemia is typical of: A A. intravascular hemolysis B. carcinoma of common bile ducts C. carcinoma of gall bladder D. None of these
Last Answer : intravascular hemolysis
Description : In Vitamin D poisoning (hyper-vitaminosis) (A) Both serum and urinary “Ca” (B) The serum Ca is low and urinary calcium high (C) The serum “Ca” is increased and urinary “Ca” is normal (D) Both serum and urinary “Ca” are low
Description : One of the symptoms of low serum potassium concentration includes (A) Muscle weakness (B) Confusion (C) Numbness (D) Tingling of extremities WATER AND ELECTROLYTE BALANCE 283
Description : After operative removal of the parathyroid glands resulting into hypoparathyroidism the concentration of the serum calcium may drop below (A) 11 mg (B) 10 mg (C) 9 mg (D) 7 mg
Description : An extracellular fluid having a higher concentration of chloride than serum is (A) Bile (B) Sweat (C) CSF (D) Pancreatic juice
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) is decreased in (A) Rickets (B) Hypoparathyroidism (C) Hyperparathyroidism (D) Renal failure
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) in children is about (A) 30 (B) 40 (C) 50 (D) 60
Description : The product of serum calcium concentration (mg/dl) and serum inorganic phosphorous concentration (mg/dl) in adults is about (A) 30 (B) 40 (C) 50 (D) 60
Description : The correct statement about serum inorganic phosphorous concentration is (A) It is higher in men than in women (B) It is higher in women than in men (C) It is higher in adults than in children (D) It is higher in children than in adults
Description : The normal serum concentration of ceruloplasmin in mg/100 ml varies between (A) 5–10 (B) 10–20 (C) 25–43 (D) 50–100
Description : The normal serum of concentration of copper in mg/100 ml varies between (A) 0–5 (B) 50–100 (C) 100–200 (D) 200–300
Description : The immunoglobulin having least concentration in serum is (A) Ig A (B) Ig M (C) Ig D (D) Ig E
Description : The normal serum concentration of 24,25- dihydroxycholecalciferol in ng/ml is (A) 8–20 (B) 25–50 (C) 1–5 (D) 60–100
Description : The normal serum concentration of 1,25- dihydroxycholecalciferol in pg/ml is (A) 26–65 (B) 1–5 (C) 5–20 (D) 80–100
Description : The normal serum concentration of 25-hydroxycholecalciferol in ng/ml is (A) 0–8 (B) 60–100 (C) 100–150 (D) 8–55
Description : The normal serum concentration of vitamin A in mg/100 ml is (A) 5–10 (B) 15–60 (C) 100–150 (D) 0–5
Description : The following statement(s) is/are true concerning initial microbiologic diagnostic techniques. a. Appropriate expeditious transport of specimens to the microbiology laboratory is essential for obtaining accurate ... a 4-to 8-fold increase over the MIC to be considered clinically efficacious.
Last Answer : Answer: a, c, d Because most surgical infections are polymicrobial, specimens should be cultured for aerobic and anaerobic bacteria, as well as fungi. Although aerobic and aerotolerant ... fold increase over MIC during the peak serum level have been demonstrated to be clinically efficacious
Description : Rank the following laboratory tests and procedures in terms of their relative value to a 65-year-old woman who is to undergo elective resection of a sigmoid cancer. A. Carcinoembryonic antigen (CEA). B. ... Arterial blood oxygen tension (PaO 2) on room air. G. Serum sodium concentration (Na+).
Last Answer : Answer: CDFEBAG DISCUSSION: The most important test by far is the electrocardiogram, with its capacity to indicate signs of occult heart disease. The second most important evaluation is the hemoglobin ... for resection of the colon is always normal and would be of least value among these tests
Description : Relative to fexofenadine, diphenhydramine is more likely to (a) Be used for treatment of asthma (b) Be used for treatment of gastroesophageal reflux disease (c) Cause cardiac arrhythmias in ... ) Have efficacy in the prevention of motion sickness (e) Increase the serum concentration of warfarin
Last Answer : Ans: D
Description : A 55 year-old female complaining of vague tiredness is found to have a serum corrected calcium concentration of 2.9 mmol/l. Examination was unremarkable. Which of the following results ... 4) Low normal plasma phosphate concentration 5) Low normal serum 25-hydroxyvitamin D concentration
Last Answer : Answers-3 Bit too easy really. A high or even normal PTH concentration in the presence of hypercalcaemia would support the diagnosis of hyperparathyroidism. A high urinary Calcium concentration may ... but neither confirm the diagnosis. Elevated 1,25 VitD suggests a diagnosis of hypervitaminosis D.
Description : Hyperventilation: a. decreases cerebral blood flow b. increases ionized calcium concentration in the serum c. causes hypocapnia d. causes metabolic alkalosis
Last Answer : causes hypocapnia
Description : The following are found in higher concentration in the tear than in the serum: a. sodium b. potassium c. Ig G d. glucose
Last Answer : potassium
Description : The tear film: a. has a higher pH than the serum b. has a lower concentration of glucose than the serum c. the oily component is secreted by the meibomian glands d. all above
Last Answer : all above
Description : For therapeutic effect in manic depressive illness, steady-state serum lithium concentration should be maintained between: A. 0.2–0.4 mEq/L B. 0.5–0.8 mEq/L C. 1.0–1.3 mEq/L D. 1.5–2.5 mEq/L
Last Answer : B. 0.5–0.8 mEq/L