Description : Which one of the following statements concerning glucose metabolism is correct? (A) The conversion of Glucose to lactate occurs only in the R.B.C (B) Glucose enters most cells by a mechanism in ... ) An elevated level of insulin leads to a decreased level of fructose 2, 6-bisphosphate in hepatocyte
Last Answer : C
Description : Compared to the resting state, vigorously contracting muscle shows (A) An increased conversion of pyruvate to lactate (B) Decreased oxidation of pyruvate of CO2 and water (C) A decreased NADH/NAD+ ratio (D) Decreased concentration of AMP CARBOHYDRATES AND CARBOHYDRATE METABOLISM 21
Last Answer : A
Description : Isoenzymes of lactate dehydrogenase are useful for the diagnosis of (A) Heart disease (B) Kidney disease (C) Liver disease (D) Both (A) and (C)
Last Answer : Answer : D
Description : The number of ATP molecules required to convert 2 molecules of lactate into glucose in mammalian liver is (A) 2 (B) 4 (C) 5 (D) 6
Description : Cori’s cycle transfers (A) Glucose from muscles to liver (B) Lactate from muscles to liver (C) Lactate from liver to muscles (D) Pyruvate from liver to muscles
Last Answer : B
Description : Cholesterol is transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL
Description : Triglycerides are transported from liver to extrahepatic tissues by (A) Chylomicrons (B) VLDL (C) HDL (D) LDL
Last Answer : Answer : B
Description : Ammonia is transported from muscles to liver mainly in the form of (A) Free ammonia (B) Glutamine (C) Asparagine (C) Alanine
Description : Anion gap of plasma can be due to the presence of all the following except (A) Bicarbonate (B) Lactate (C) Pyruvate (D) Citrate
Last Answer : Answer : A
Description : Quantitatively, the most significant buffer system in plasma is (A) Phosphate buffer system (B) Carbonic acid-bicarbonate buffer system (C) Lactic acid-lactate buffer system (D) Protein buffer system
Description : Zn is present as prosthetic group in this enzyme: (A) Carbonic anhydrase (B) Carboxy peptidase (C) Lactate dehydrogenase (D) All of these
Description : Schardinger’s enzyme is (A) Lactate dehydrogenase (B) Xanthine dehydrogenase (C) Uric oxidase (D) L amino acid dehydrogenase
Description : Which of the following is not having an apoenzyme and coenzyme? (A) Lactate dehydrogenase (B) Succinate dehydrogenase (C) Malate dehydrogenase (D) Pepsin
Description : Coenzymes derived from the vitamin shown below are required by which of the following enzymes? (A) Lactate dehydrogenase (B) Glutamate dehydrogenase (C) Pyruvate dehydrogenase (D) Malate dehydrogenase
Last Answer : Answer : C
Description : Glucose cannot be synthesized from (A) Glycerol (B) Lactate (C) Alanine (D) Leucine
Description : A unique by-product of glycolysis in erythrocytes is (A) Lactate (B) 1, 3-Biphosphoglycerate (C) 2, 3-Biphosphoglycerate (D) All of these
Description : Phosphofructokinase is allosterically inhibited by (A) Fructose-1, 6-biphosphate (B) Lactate (C) Pyruvate (D) Citrate
Description : Which of the following is an allosteric enzyme? (A) Phosphohexose isomerase (B) Phosphotriose isomerase (C) Lactate dehydrogenase (D) Phosphofructokinase
Description : End product of aerobic glycolysis is (A) Acetyl CoA (B) Lactate (C) Pyruvate (D) CO2 and H2O
Description : Lactate dehydrogenase is a (A) Monomer (B) Dimer (C) Tetramer (D) Hexamer
Description : Lactate dehydrogenase is located in (A) Lysosomes (B) Mitochondria (C) Cytosol (D) Microsomes
Description : The first enzyme found to have isoenzymes was (A) Alkaline Phosphatase (B) Lactate dehydrogenase (C) Acid Phosphatase (D) Creatine kinase
Description : Which of the following isoenzyme of lactate dehydrogenase is raised in serum in myocardial infarction: (A) LD1 (B) LD2 (C) LD1 and LD2 (D) LD5
Description : Serum lactate dehydrogenase rises in (A) Viral hepatitis (B) Myocardial infarction (C) Carcinomatosis (D) All of these
Description : In non shivering thermogenesis (A) Glucose is oxidized to lactate (B) Fatty acids uncouple oxidative phosphorylation (C) Ethanol is formed (D) ATP is burned for heat production
Description : Which of the following intermediates of metabolism can be both a precursor and a product of glucose? (A) Lactate (B) Pyruvate (C) Alanine (D) Acetyl-CoA
Description : Pyruvate dehydrogenase a multienzyme complex is required for the production of (A) Acetyl-CoA (B) Lactate (C) Phosphoenolpyruvate (D) Enolpyruvate
Description : A reaction which may be considered an isomerisation is (A) Glucose 6-Phosphate fructose 6 phosphate (B) 3-Phosphoglycerate 2-phosphoglycerate (C) 2-phosphoglycerate phosphoenolpyruvate (D) Pyruvate Lactate
Description : Erythrocytes under normal conditions and microorganisms under anaerobic conditions may accumulate (A) NADPH (B) Pyruvate (C) Phosphoenolpyruvate (D) Lactate
Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase
Description : An enzyme catalyzing oxidoreduction, using oxygen as hydrogen acceptor is (A) Cytochrome oxidase (B) Lactate dehydrogenase (C) Malate dehydrogenase (D) Succinate dehydrogenase
Description : Example of an extracellular enzyme is (A) Lactate dehydrogenase (B) Cytochrome oxidase (C) Pancreatic lipase (D) Hexokinase
Description : Vitamin B12 deficiency can be diagnosed by urinary excretion of (A) Pyruvate (B) Methylmalonate (C) Malate (D) Lactate
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Description : Which one of the following compounds cannot give rise to the net synthesis of Glucose? (A) Lactate (B) Glycerol (C) α-ketoglutarate (D) Acetyl CoA
Description : Which one of the following would be expected in pyruvate kinase deficiency? (A) Increased levels of lactate in the R.B.C (B) Hemolytic anemia (C) Decreased ratio of ADP to ATP in R.B.C (D) Increased phosphorylation of Glucose to Glucose-6-phosphate
Description : Before pyruvic acid enters the TCA cycle it must be converted to (A) Acetyl CoA (B) Lactate (C) α-ketoglutarate (D) Citrate
Description : When O2 supply is inadequate, pyruvate is converted to (A) Phosphopyruvate (B) Acetyl CoA (C) Lactate (D) Alanine
Description : Which of the following metabolite integrates glucose and fatty acid metabolism? (A) Acetyl CoA (B) Pyruvate (C) Citrate (D) Lactate
Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate
Description : Lactate formed in muscles can be utilised through (A) Rapoport-Luebeling cycle (B) Glucose-alanine cycle (C) Cori’s cycle (D) Citric acid cycle
Description : In which condition pyruvate is produced, and when lactate?
Last Answer : In aerobic condition pyruvate is produced. When oxygen is lacking, lactate is produced.
Description : Lactate dehydrogenase has how many iso-enzymes?
Last Answer : H4, H3M, H2M2, M3H and M4 varieties, forming five iso-enzymes. All these five forms are seen in all persons.
Description : Lactate dehydrogenase has how many polypeptide subunits?
Last Answer : Four. It is a tetramer.
Description : Ribosomes similar to those of bacteria found in (A) Plant nuclei (B) Cardiac muscle cytoplasm (C) Liver endoplasmic reticulum (D) Neuronal cytoplasm
Description : Ribosomes similar to those of bacterial found in (A) Plant nucei (B) Cardiac muscle cytoplasm (C) Liver endoplasmic reticulum (D) Neuronal cytoplasm
Description : Which is incorrect ? Epinephrin promotes the glycogenolysis in (A) Muscle (B) Liver (C) Heart (D) None of these
Description : Insulin is required for the active uptake of glucose by most of the cells except (A) Muscle cells (B) Renal tubular cells (C) Adipocytes (D) Liver cells
Description : Glucagon (A) Increases protein synthesis (B) Inhibits lipolysis in adipocytes (C) Increases gluconeogenesis in liver (D) Stimulates muscle glycogenolysis
Description : Epinephrine stimulates glycogenolysis in (A) Liver (B) Muscle (C) Liver and muscle (D) Kidney