Description : Ketosis reflects (A) Increased hepatic glucose liberation (B) Increased fatty acid oxidation (C) Increased carbohydrate utilisation (D) Incresed gluconeogenesis
Last Answer : Answer : B
Description : Conversion of Alanine to carbohydrate is termed: (A) Glycogenesis (B) Gluconeogenesis (C) Glycogenolysis (D) Photosynthesis
Last Answer : B
Description : Glucocorticoids impair carbohydrate tolerance by: A. Promoting gluconeogenesis in liver B. Depressing glucose uptake into skeletal muscles C. Inhibiting insulin secretion D. Both A and B are correct
Last Answer : D. Both A and B are correct
Description : All of the following statements about thioredoxin reductase are true except: (A) It requires NADH as a coenzyme (B) Its substrates are ADP, GDP, CDP and UDP (C) It is activated by ATP (D) It is inhibited by dADP
Last Answer : Answer : A
Description : The chemical forces that bind most coenzymes and substrates to enzymes such as LDH are (A) Hydrogen bonds (B) Peptide bonds (C) Coordinate bonds (D) Covalent bonds
Last Answer : Answer : D
Description : Lock' and Key' model of enzyme action proposed by Fisher implies that (A) The active site is flexible and adjusts to substrate (B) The active site requires removal of PO4 group ( ... complementary in shape to that of the substrate (D) Substrates change conformation prior to active site interaction
Last Answer : Answer : C
Description : Enzymes which catalyse binding of two substrates by covalent bonds are known as (A) Lyases (B) Hydrolases (C) Ligases (D) Oxidoreductases
Description : Enzymes leading to the high energy phosphorylation of substrates during glycolysis include which of the following? (A) Phosphoglycerate kinase (B) Enolase (C) Pyruvate Kinase (D) Glyceraldehyde-3-phosphate dehydrogenase
Description : Enzyme involved in joining together two substrates is (A) Glutamine synthetase (B) Aldolase (C) Gunaine deaminase (D) Arginase
Description : If curve X in the graph (below) represents no inhibition for the reaction of the enzyme with its substrates, the curve representing the competitive inhibition, of the same reaction is (A) A (B) B (C) C (D) D
Description : Fischer's lock and key' model of the enzyme action implies that (A) The active site is complementary in shape to that of substance only after interaction. (B) The active site is ... change conformation prior to active site interaction (D) The active site is flexible and adjusts to substrate
Description : Most amino acids are substrates for transamination except (A) Alanine (B) Threonine (C) Serine (D) Valine
Description : Carbon skeleton of the following amino acid can serve as a substance for gluconeogenesis (A) Cysteine (B) Aspartate (C) Glutamate (D) All of these
Description : Epinephrine causes in muscle: (A) Gluconeogenesis (B) Glycogenesis (C) Glycolysis (D) Glycogenolysis
Description : Which one of the following statements is incorrect? (A) Insulin increases glucose phosphorylation (B) Insulin increases glycolysis (C) Insulin augments HMP shunt (D) Insulin promotes gluconeogenesis
Description : Excessive secretion of glucocorticoids raises blood glucose by (A) Decreasing glycogenesis (B) Increasing glycogenolysis (C) Increasing gluconeogenesis (D) Inhibiting HMP shunt
Description : Glucocorticoids increase all of the following except (A) Gluconeogenesis (B) Lipolysis in extremities (C) Synthesis of elcosanoida (D) Hepatic glycogenesis
Description : Epinephrine increases all of the following except (A) Glycogenolysis in muscles (B) Lipolysis in adipose tissue (C) Gluconeogenesis in muscles (D) Glucagon secretion
Description : Epinephrine decreases (A) Glycogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Lipolysis
Description : Insulin increases (A) Glycogenesis (B) Gluconeogenesis (C) Lipolysis (D) Blood glucose
Description : Insulin decreases (A) Glycogenesis (B) Glyolysis (C) Gluconeogenesis (D) Tubular reabsorption of glucose
Description : Glucagon (A) Increases protein synthesis (B) Inhibits lipolysis in adipocytes (C) Increases gluconeogenesis in liver (D) Stimulates muscle glycogenolysis
Description : Insulin stimulates (A) Hepatic glycogenolysis (B) Hepatic glycogenesis (C) Lipolysis (D) Gluconeogenesis
Description : Growth hormone causes hyperglycemia. It is a result of (A) Decreased peripheral utilization of glucose (B) Decreased hepatic production via gluconeogenesis (C) Increased glycolysis in muscle (D) Decrersed lipolysis
Description : Gluconeogenesis does not occur in (A) Brain (B) Kidneys (C) Muscles (D) Liver
Description : The glycerol for fatty acid esterification in adipocytes is (A) For the most part, derived from glucose (B) Obtained primarily from phosphorylation of glycerol by glycerol kinase (C) Formed from gluconeogenesis (D) Formed from glycogenolysis ENZYMES 153
Description : Phlorizin inhibits (A) Renal tubular reabsorption of glucose (B) Glycolysis (C) Gluconeogenesis (D) Glycogenolysis
Description : An enzyme involved in gluconeogenesis is (A) Pyruvate kinase (B) Pyruvate carboxylase (C) Hexokinase (D) Phosphohexose isomerase
Description : The sites for gluconeogenesis are (A) Liver and kidney (B) Skin and pancreas (C) Lung and brain (D) Intestine and lens of eye
Description : Most major metabolic pathways are considered mainly either anabolic or catabolic. Which of the following pathway is most correctly considered to be amphibolic? (A) Citric acid cycle (B) Gluconeogenesis (C) Lipolysis (D) Glycolysis
Description : NADP is required as a coenzyme in (A) Glycolysis (B) Citric acid cycle (C) HMP shunt (D) Gluconeogenesis
Description : A pathway that requires NADPH as a cofactor is (A) Extramitochondrial folic acid synthesis (B) Ketone body formation (C) Glycogenesis (D) Gluconeogenesis
Description : The process of breakdown of glycogen to glucose in the liver and pyruvate and lacate in the muscle is known as (A) Glyogenesis (B) Glycogenolysis (C) Gluconeogenesis (D) Cellular degradation
Description : Hypoglycemia depresses insulin secretion and thus increases the rate of (A) Hydrolysis (B) Reduction (C) Gluconeogenesis (D) Respiratory acidosis
Description : Which of the following products of triacylglycerol breakdown and subsequent β-Oxidation may undergo gluconeogenesis? (A) Acetyl CoA (B) Porpionyl CoA (C) All ketone bodies (D) Some amino acids
Description : In ad ipose t issue prostag land ins decrease (A) Lipogenesis (B) Lipolysis (C) Gluconeogenesis (D) Glycogenolysis
Description : The synthesis of glucose from pyruvate by gluconeogenesis (A) Requires the participation of biotin (B) Occurs exclusively in the cytosol (C) Is inhibited by elevated level of insulin (D) Requires oxidation/reduction of FAD
Last Answer : A
Description : Which of the following reactions is unique to gluconeogenesis? (A) Lactate Pyruvate (B) Phosphoenol pyruvate pyruvate (C) Oxaloacetate phosphoenol pyruvate (D) Glucose-6-phosphate Fructose-6-phosphate
Last Answer : C
Description : Which of the following statements regarding T.C.A cycle is true? (A) It is an anaerobic process (B) It occurs in cytosol (C) It contains no intermediates for Gluconeogenesis (D) It is amphibolic in nature
Last Answer : D
Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis
Description : Synthesis of Glucose from amino acids is termed as (A) Glycolysis (B) Gluconeogenesis (C) Glycogenesis (D) Lipogenesis
Description : Two conditions in which gluconeogenesis is increased are (A) Diabetes mellitus and atherosclerosis (B) Fed condition and thyrotoxicosis (C) Diabetes mellitus and Starvation (D) Alcohol intake and cigarette smoking
Description : Which one of the following is a rate limiting enzyme of gluconeogenesis? (A) Hexokinase (B) Phsophofructokinase (C) Pyruvate carboxylase (D) Pyruvate kinase
Description : The 4 rate limiting enzymes of gluconeogenesis are (A) Glucokinase, Pyruvate carboxylae phosphoenol pyruvate carboxykinase and glucose-6-phosphatase (B) Pyruvate carboxylase, phosphoenol ... fructokinase, pyruvate carboxylase, phosphoenol pyruvate carboxykinase and fructose 1, 6 diphosphatase
Description : Gluconeogenesis is increased in the following condition: (A) Diabetes insipidus (B) Diabetes Mellitus (C) Hypothyroidism (D) Liver diseases
Description : The blood sugar raising action of the hormones of suprarenal cortex is due to (A) Gluconeogenesis (B) Glycogenolysis (C) Glucagon-like activity (D) Due to inhibition of glomerular filtration
Description : The conversion of alanine to glucose is termed (A) Glycolysis (B) Oxidative decarboxylation (C) Specific dynamic action (D) Gluconeogenesis
Description : Ethanol decreases gluconeogenesis by (A) Inhibiting glucose-6-phosphatase (B) Inhibiting PEP carboxykinase (C) Converting NAD+ into NADH and decreasing the availability of pyruvate (D) Converting NAD+ into NADH and decreasing the availability of lactate
Description : An amphibolic pathway among the following is (A) HMP shunt (B) Glycolysis (C) Citirc acid cycle (D) Gluconeogenesis
Description : Gluconeogenesis is decreased by (A) Glucagon (B) Epinephrine (C) Glucocorticoids (D) Insulin