Description : Bassen-Kornzweig syndrome is due to (A) Absence of Apo-C-II (B) Defect in Apo-B synthesis (C) Absence of Apo-E (D) Absence of Apo-D
Last Answer : Answer : B
Description : Wolman’s disease is due to deficiency of (A) Cholesteryl ester hydrolase (B) Hexosaminidase A (C) α-Fucosidase (D) Arylsulphatase A
Last Answer : Answer : A
Description : Tyrosinosis is due to defect in the enzyme: (A) Fumarylacetoacetate hydrolase (B) p-Hydroxyphenylpyruvate hydroxylase (C) Tyrosine transaminase (D) Tyrosine hydroxylase
Description : Richner-Hanhart syndrome is due to defect in (A) Tyrosinase (B) Phenylalanine hydroxylase (C) Hepatic tyrosine transaminase (D) Fumarylacetoacetate hydrolase
Description : LCAT is (A) Lactose choline alamine transferse (B) Lecithin cholesterol acyl transferase (C) Lecithin carnitine acyl transferase (D) Lanoleate carbamoyl acyl transferase
Description : Salivary lipase hydrolyses the ester bond at (A) Position 1 of triglycerides (B) Position 2 of triglycerides (C) Position 3 of triglycerides (D) All of these
Last Answer : Answer : C
Description : LCAT activity is associated with which of the lipo-protein complex? (A) VLDL (B) Chylomicrones (C) IDL (D) HDL
Last Answer : Answer : D
Description : Six months after beginning atorvastatin, the patient's total and LDL cholesterol concentrations remained above normal and he continued to have anginal attacks despite good adherence to his antianginal ... Increased endocytosis of HDL by the liver (e) Increased lipid hydrolysis by lipoprotein lipase
Last Answer : Ans: C
Description : Activity of ceruloplasmin shown in vitro: (A) Reductase (B) Hydrolase (C) Ligase (D) Oxidase
Description : Cholesterol circulates in blood stream chiefly as (A) Free cholesterol (B) Ester cholesterol (C) Low density lipoproteins (D) Low density lipoproteins and high density lipoproteins
Description : Most animal tissues contain appreciable amounts of lipid, when in the form of depot fat it consists largely of (A) Cholesterol ester (B) Phosphatides (C) Chylomicrons (D) Triacylglycerol
Description : Palmitic, oleic or stearic acid ester of cholesterol used in manufacture of cosmetic creams is (A) Elaidic oil (B) Lanoline (C) Spermaceti (D) Chaulmoogric oil FATS AND FATTY ACID METABOLISM 75
Description : Which of the following statement is correct about membrane cholesterol? (A) The hydroxyl group is located near the centre of the lipid layer (B) Most of the cholesterol is in the form ... forms a rigid, planar structure (D) The hydrocarbon chain of cholesterol projects into the extracellular fluid
Last Answer : C
Description : ‘Clearing factor’ is (A) Lipoprotein lipase (B) Crotonase (C) 7-dehydro cholesterol (D) β-sitosterol
Description : This interferes with cholesterol absorption (A) Lipoprotein lipase (B) Creatinase (C) 7-dehydrocholesterol (D) β-sitosterol
Description : Which of the following regulates lipolysis in adipocytes? (A) Activation of fatty acid synthesis mediated by CAMP (B) Glycerol phosphorylation to prevent futile esterification of fatty acids (C) ... result of hormone stimulated increases in CAMP levels (D) Activation of CAMP production by Insulin
Description : The apolipoprotein which acts as activator of LCAT is (A) A-I (B) A-IV (C) C-II (D) D
Description : The lipoprotein associated with activation of LCAT is (A) HDL (B) LDL (C) VLDL (D) IDL
Description : What is LCAT?
Last Answer : The free cholesterol is esterified by LCAT the esterified cholesterol is then incorporated into HDL disc, to form mature HDL. So for excretion of cholesterol, LCAT is necessary.
Description : Hyperargininemia, a defect in urea synthesis develops due to deficiency of the enzyme: (A) Ornithine transcarbamoylase (B) Argininosuccinase (C) Arginase (D) Argininosuccinate synthetase ENZYMES 157
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Description : Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase
Description : Pancreatic lipase requires for its activity: (A) Co-lipase (B) Bile salts (C) Phospholipids (D) All of these
Description : Which of the following statement is correct about membrane cholesterol? (A) The hydroxyl group is located near the centre of the lipid layer (B) Most of the cholesterol is in the form ... forms a rigid, planar Structure (D) The hydrocarbon chain of cholesterol projects into the extracellular fluid
Last Answer : (C) The steroid nucleus form forms a rigid, planar Structure
Description : The biochemical mechanism of action of digitalis is associated with (a) A decrease in calcium uptake by the sarcoplasmic reticulum (b) An increase in ATP synthesis (c) A modification of the actin molecule (d) An increase in systolic intracellular calcium levels (e) A block of sodium/calcium exchange
Last Answer : Ans: D
Description : Genes control (a) Protein synthesis but not heredity (b) Protein synthesis and heredity (c) Heredity but not protein synthesis (d) Biochemical reaction of some enzymes
Last Answer : Ans:(b)
Description : Which enzyme is concerned with transfer of electrons? (A) Desmolase (B) Hydrolase (C) Dehydrogenase (D) Transaminase
Description : In which of the following types of enzymes, water may be added to a C—C double bond without breaking the bond? (A) Hydrolase (B) Hydratase (C) Hydroxylase (D) Oxygenase
Description : In which of the following types of enzyme water may be added to a C—C double bond without breaking the bond? (A) Hydrolase (B) Hydratase (C) Hydroxylase (D) Esterase
Description : If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity ... C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167
Description : Urease is a (A) Lyase (B) Ligase (C) Isomerase (D) Hydrolase
Description : The decarboxylation reaction in HMP shunt is catalysed by (A) Gluconolactone hydrolase (B) 6-Phosphogluconate dehydrogenase (C) 6-Phosphogluconate decarboxylase (D) Transaldolase
Description : The enzyme hexokinase is a (A) Hydrolase (B) Oxidoreductase (C) Transferase (D) Ligase
Description : Neonatal tyrosinemia is due to deficiency of the enzyme: (A) p-Hydroxyphenylpyruvate hydroxylase (B) Fumarylacetoacetate hydrolase (C) Phenylalanine hydroxylase (D) Tyrosine dehydrogenase
Description : The enzyme which can add water to a carbon-carbon double bond or remove water to create a double bond without breaking the bond is (A) Hydratase (B) Hydroxylase (C) Hydrolase (D) Esterase
Description : A Holoenzyme is (A) Functional unit (B) Apo enzyme (C) Coenzyme (D) All of these
Description : Pancreatic lipose is an enzyme which hydrolyzes facts. It acts as a/an (A) peptidase (B) hydrolase (C) carbohydrates (D) dehydrogenase
Description : Nascent HDL of intestinal origin acquires Apo C and Apo E from (A) Chylomicrons (B) VLDL (C) LDL (D) HDL of the hepatic origin
Description : Nascent HDL of intestinal origin lacks (A) Apo A (B) Apo C (C) Apo E (D) Apo C and Apo E
Description : LDL receptor is specific for (A) Apo B-48 and Apo B 100 (B) Apo B-48 and Apo E (C) Apo B-100 and Apo D (D) Apo B-100 and apo D
Description : Receptors for chylomicron remnants are (A) Apo A specific (B) Apo B-48 specific (C) Apo C specific (D) Apo E specific
Description : Alkaptonuria occurs due to deficiency of the enzyme: (A) Maleylacetoacetate isomerase (B) Homogentisate oxidase (C) p-Hydroxyphenylpyruvate hydroxylase (D) Fumarylacetoacetate hydrolase
Description : A significant feature of Broad Beta disease is (A) Hypocholesterolemia (B) Hypotriacylglycerolemia (C) Absence of Apo-D (D) Abnormality of Apo-E
Description : A significant feature of Tangier disease is (A) Impairment of chylomicron formation (B) Hypotriacylglycerolmia (C) Absence of Apo-C-II (D) Absence of Apo-C-I
Description : The largest alpolipoprotein is (A) Apo E (B) Apo B-48 (C) Apo B-100 (D) Apo A-I
Description : Transfer of the carbamoyl moiety of carbamoyl phosphate to ornithine is catalysed by a liver mitochondrial enzyme: (A) Carbamoyl phosphate synthetase (B) Ornithine transcarbamoylase (C) N-acetyl glutamate synthetase (D) N-acetyl glutamate hydrolase
Description : The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D
Description : Give an example of a hydrolase.
Last Answer : Acetyl choline esterase.
Description : Which of the following is wrongly matched in the given table? Microbe Product Application (a) Streptococcus Streptokinase Removal of clot from blood vessel (b) Clostridium butylicum Lipase ... Cyclosporin A Immuno- suppressive drug (d) Monascus purpureus Statins Lowering of blood cholesterol
Last Answer : (b) Clostridium butylicum Lipase Removal of oil stains
Description : The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level
Last Answer : C. It increases the incidence of myopathy due to statins