Description : ‘Clearing factor’ is (A) Lipoprotein lipase (B) Crotonase (C) 7-dehydro cholesterol (D) β-sitosterol
Last Answer : Answer : A
Description : Six months after beginning atorvastatin, the patient's total and LDL cholesterol concentrations remained above normal and he continued to have anginal attacks despite good adherence to his antianginal ... Increased endocytosis of HDL by the liver (e) Increased lipid hydrolysis by lipoprotein lipase
Last Answer : Ans: C
Description : The following is true of bezafibrate except: A. It activates lipoprotein lipase B. It mainly lowers serum triglyceride level with smaller effect on LDL cholesterol level C. It increases the incidence of myopathy due to statins D. It tends to lower plasma fibrinogen level
Last Answer : C. It increases the incidence of myopathy due to statins
Description : The β-ring of 7-dehydrocholesterol is cleaved to form cholecalciferol by (A) Infrared light (B) Dim light (C) Ultraviolet irridation with sunlight (D) Light of the tube lights
Last Answer : Answer : C
Description : Steroid hormones are synthesised from (A) Cholesterol (B) 7-Dehydrocholesterol (C) Calcitriol (D) 7-Hydroxycholesterol
Description : Calcitriol inhibits the conversion of (A) Cholesterol into 7-dehydrocholesterol (B) Cholecalciferol into 1-hydroxycholecalciferol (C) Cholecalciferol into 25-hydroxycholecalciferol (D) 25-Hydroxycholecalciferol into 1,25- dihydroxycholecalciferol
Last Answer : Answer : D
Description : Parathormone is required for the conversion of (A) Cholecalciferol into 1-hydroxycholecalciferol (B) Cholecalciferol into 25-hydroxycholecalciferol (C) 25-Hydroxycholecalciferol into calcitriol (D) Cholesterol into 7-dehydrocholesterol
Description : A metabolite which is common to pathways of cholesterol biosynthesis from acetyl-CoA and cholecalciferol formation from cholesterol is (A) Zymosterol (B) Lumisterol (C) Ergosterol (D) 7 Dehydrocholesterol
Description : Select the hypocholesterolemic drug which interferes with intestinal absorption of bile salts and cholesterol, and secondarily increases cholesterol turnover in the liver: A. Gemfibrozil B. Cholestyramine C. Lovastatin D. Bezafibrate
Last Answer : B. Cholestyramine
Description : An important zinc containing enzyme is (A) Carboxypeptidase A (B) Isocitrate dehydrogenase (C) Cholinesterate (D) Lipoprotein lipase
Description : The principal action of insulin in adipose tissue is to inhibit the activity of the (A) Hormone sensitive lipoprotein lipase (B) Glycerol phosphate acyltransferase (C) Acetyl-CoA carboxylase (D) Pyruvate dehydrogenase
Description : A non-functional plasma enzyme is (A) Psudocholinesterase (B) Lipoprotein lipase (C) Proenzyme of blood coagulation (D) Lipase
Description : An example of functional plasma enzyme is (A) Lipoprotein lipase (B) Amylase (C) Aminotransferase (D) Lactate dehydrogenase
Description : Non steroidal anti inflammatory drugs, such as aspirin act by inhibiting the activity of the enzyme: (A) Lipoxygenase (B) Cyclooxygenase (C) Phospholipase A2 (D) Lipoprotein lipase
Last Answer : Answer : B
Description : The triacyl glycerol present in plasma lipoproteins are hydrolyzed by (A) Linqual lipase (B) Pancreatic lipase (C) Colipase (D) Lipoprotein lipase
Description : Genetic deficiency of lipoprotein lipase causes hyperlipoproteinaemia of following type: (A) Type I (B) Type IIa (C) Type IIb (D) Type V
Description : Apolipoprotein C-II is an activator of (A) Lecithin cholesterola acyl transferase (B) Phospholipase C (C) Extrahepatic lipoprotein lipase (D) Hepatic lipoprotein lipase
Description : Lipoprotein lipase deficiency is associated with: 1) Abetalipoproteinaemia 2) Combined hyperlipidaemia 3) Familial combined hyperlipidaemia 4) Familial Hypercholesterolaemia 5) Marked Hypertriglyceridaemia
Last Answer : Answers-5 Lipoprotein lipase deficiency is autosomal recessive and associated with increased chylomicrons and marked hypertriglyceridaemia.
Description : The immediate parent of α, β and γ endorphins is (A) Pro-opiomelanocortin (B) β-lipotropin (C) ATCH (D) Lipoprotein
Description : The compound which has the lowest density is (A) Chylomicron (B) β-Lipoprotein (C) α-Lipoprotein (D) pre β-Lipoprotein
Description : The β-lipoprotein fraction increases in severe (A) Diabetes Mellitus (B) Uremia (C) Nephritis (D) Muscular dystrophy
Description : Free fatty acids are transported in the blood (A) Combined with albumin (B) Combined with fatty acid binding protein (C) Combined with β -lipoprotein (D) In unbound free salts
Description : Which of the following is a dipeptide? (A) Anserine (B) Glutathione (C) Glucagon (D) β -Lipoprotein
Description : A 65-year old patient has colon carcinoma metastatic to the liver and lungs. He has had a weight loss of 10 kg. Cytokine-dependent tumor cachexia is attributable to which of the ... is impaired e. Partial reversal of differentiated adipocytes to pre-adipocyte morphology and gene expression occurs
Last Answer : Answer: a, b, c, d, e Tumor cachexia appears to be mediated by TNFa. Lipopolysaccharide (LPS), as well as other cytokines, activate a variety of inflammatory cells, most ... chronic syndromes of anorexia, weight loss, and cachexia that are associated with both chronic infection and malignancy
Description : Choose the correct statement(s) about actions of insulin: A. It favours translocation of glucose transporters from intracellular site to the plasma membrane B. It enhances transcription of lipoprotein ... vascular endothelium C. It increases production of the enzyme glucokinase D. All of the above
Last Answer : D. All of the above
Description : The major source of extracellular cholesterol for human tissue is (A) Very low density lipoprotein (B) High density lipoprotein (C) Low density lipoprotein (D) Albumin
Description : This lipoprotein removes cholesterol from the body (A) HDL (B) VLDL (C) IDL (D) Chylomicrons
Description : The lipoprotein richest in cholesterol is (A) Chylomicrons (B) VLDL (C) LDL (D) HDL
Description : With respect to lipoprotein transport and metabolism in the body, the following statements are correct EXCEPT: 1) Arterial walls contain cells with LDL receptors. 2) Cholesterol is required for the ... is assembled in the extracellular space. 5) VLDL transformation to LDL occurs in adipose tissue.
Last Answer : Answers-3 Chylomicrons are formed in the gut from exogenous triacylglycerols and cholesterol. They are released into the lymph and thereby enter the blood.They are not formed in the liver.
Description : Maximum cholesterol content is in which lipoprotein?
Last Answer : LDL (Beta lipoprotein).
Description : A provitamin D synthesized in human beings is (A) Ergosterol (B) 7-Dehydrocholesterol (C) Cholecalciferol (D) 25-Hydroxycholecalciferol
Description : Provitamin D3 is (A) Cholecalciferol (B) Ergosterol (C) 7-Dehydrocholesterol (D) Ergocaliferol
Description : The most potent Vitamin D metabolite is (A) 25-Hydroxycholecalciferol (B) 1,25-Dihydroxycholecalciferol (C) 24, 25-Dihydroxycholecalciferol (D) 7-Dehydrocholesterol
Description : The structure shown below is of (A) Cholecalciferol (B) 25-Hydroxycholecalciferol (C) Ergocalciferol (D) 7-Dehydrocholesterol
Description : Used as a laxative, liquid paraffin has the following drawbacks except: A. It interferes with absorption of fat soluble vitamins B. It is unpleasant to swallow C. It causes griping D. It can produce foreign body granulomas
Last Answer : C. It causes griping
Description : The following is true of aluminium hydroxide gel except: A. It is a weak and slowly reacting antacid B. Its acid neutralizing capacity decreases on storage C. It interferes with absorption of phosphate in the intestine D. It causes loose motions as a side effect
Last Answer : D. It causes loose motions as a side effec
Description : In abetalipoproteinemia, the biochemical defect is in (A) Apo-B synthesis (B) Lipprotein lipase activity (C) Cholesterol ester hydrolase (D) LCAT activity
Description : Which one of the following statements is true regarding digestion and absorption of food in humans? (a) Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions ... amylase in our mouth. (d) Oxyntic cells in our stomach secrete the proenzyme pepsinogen.
Last Answer : (a) Fructose and amino acids are absorbed through intestinal mucosa with the help of carrier ions like Na
Last Answer : (B) 1,25-Dihydroxycholecalciferol
Description : Characteristic absorption bands exhibited by ferrocytochrome: (A) α band (B) β band (C) α and β bands (D) α, β and γ bands
Description : The acetyl CoA formed on β-oxidation of all long chain fatty acids is metabolized under normal circumstances to (A) CO2 and water (B) Cholesterol (C) Fatty acids (D) Ketone bodies
Description : Which of the following is wrongly matched in the given table? Microbe Product Application (a) Streptococcus Streptokinase Removal of clot from blood vessel (b) Clostridium butylicum Lipase ... Cyclosporin A Immuno- suppressive drug (d) Monascus purpureus Statins Lowering of blood cholesterol
Last Answer : (b) Clostridium butylicum Lipase Removal of oil stains
Description : Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride
Description : A competitive inhibitor of an enzyme has which of the following properties? (A) It is frequently a feedback inhibitor (B) It becomes covalently attached to an enzyme (C) It decreases the Vmax (D) It interferes with substrate binding to the enzyme
Description : Hypolipidemic drugs reduce serum cholesterol and triacylglycerol. The effect of clofibrate is attributed to (A) Block in absorption from G.I.T. (B) Decrease in secretion of triacylglycerol and cholesterol ... by liver (C) Block in the reabsorption of bile acids (D) Decreased synthesis of cholesterol
Description : Lipase can act only at pH: (A) 2.5–4 (B) 3.5–5 (C) 4 to 5 (D) 5–7
Description : Correct ordering of lipoprotein molecules from lowest to the greater density is (A) LDL, IDL, VLDL, chylomicron (B) Chylomicron, VLDL, IDL, LDL (C) VLDL, IDL, LDL, chylomicron (D) LDL, VLDL, IDL, chylomicron
Description : The lipoprotein with the fastest electrophoretic mobility and lowest TG content are (A) VLDL (B) LDL (C) HDL (D) Chylomicrones
Description : The first lipoprotein to be secreted by the liver is (A) VLDL (B) nascent VLDL (C) LDL (D) IDL