Description : In abetalipoproteinemia, the biochemical defect is in (A) Apo-B synthesis (B) Lipprotein lipase activity (C) Cholesterol ester hydrolase (D) LCAT activity
Last Answer : Answer : A
Description : A significant feature of Tangier disease is (A) Impairment of chylomicron formation (B) Hypotriacylglycerolmia (C) Absence of Apo-C-II (D) Absence of Apo-C-I
Last Answer : Answer : C
Description : A significant feature of Broad Beta disease is (A) Hypocholesterolemia (B) Hypotriacylglycerolemia (C) Absence of Apo-D (D) Abnormality of Apo-E
Last Answer : Answer : D
Description : Richner-Hanhart syndrome is due to defect in (A) Tyrosinase (B) Phenylalanine hydroxylase (C) Hepatic tyrosine transaminase (D) Fumarylacetoacetate hydrolase
Last Answer : Answer : B
Description : Hyperargininemia, a defect in urea synthesis develops due to deficiency of the enzyme: (A) Ornithine transcarbamoylase (B) Argininosuccinase (C) Arginase (D) Argininosuccinate synthetase ENZYMES 157
Description : Lesch-Nyhan syndrome, the sex linked, recessive absence of HGPRTase, may lead to (A) Compulsive self destructive behaviour with elevated levels of urate in serum (B) Hypouricemia due to liver damage (C) Failure to thrive and megaloblastic anemia (D) Protein intolerance and hepatic encephalopathy
Description : In adrenogenital syndrome due to total absence of 21-hydroxylase in adrenal cortex, there is (A) Deficient secretion of glucocorticoids (B) Deficient secretion of mineralcorticoids (C) Excessive secretion of androgens (D) All of these
Description : Zellweger’s syndrome is due to inherited absence of (A) Peroxisomes (B) Phospholipase A1 (C) Acyl-Co-A dehydrogenase (D) Thiolase
Description : Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Select the correct statement. (a) Both are due to a quantitative defect in globin chain synthesis. (b ... problem of globin molecules. (d) Both are due to a qualitative defect in globin chain synthesis.
Last Answer : (b) Thalassemia is due to less synthesis of globin molecules
Description : Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement : (1) Both are due to a quantitative defect in globin chain synthesis (2 ... problem of globin molecules (4) Both are due to a qualitative defect in globin chain synthesis
Last Answer : (2) Thalassemia is due to less synthesis of globin molecules
Description : Hunter’s syndrome results from absence of (A) Hexosaminidase A (B) Iduronate sulphatase (C) Neuraminidase (D) Arylsulphatase B
Description : Complete absence of hypoxanthine guanine phospharibosyl transferase causes (A) Primary gout (B) Immunodeficiency (C) Uric acid stones (D) Lesh-Nyhan syndrome
Description : Mc Ardle’s syndrome is characterized by the absence of (A) Liver phosphorylase (B) Muscle phosphorylase (C) Branching enzyme (D) Debranching enzyme
Description : Phenytoin: 1) is a benzalkonium Derivative 2) is clinically effective serum level is in the range on 2-10 micrograms/ml. 3) A steady state blood level is achieved by 2-5 days 4) Can be used in management of alchohol withdrawl syndrome 5) Is the drug of choice in absence seizures.
Last Answer : Answers-4 Phenytoin is an imidazolidine derivative.It relates to barbiturates in chemical structure. Clinically effective seum level is in the range on 10-20 micrograms/ml. A steady state blood level is achieved by 7-10 days.
Description : Nascent HDL of intestinal origin acquires Apo C and Apo E from (A) Chylomicrons (B) VLDL (C) LDL (D) HDL of the hepatic origin
Description : Nascent HDL of intestinal origin lacks (A) Apo A (B) Apo C (C) Apo E (D) Apo C and Apo E
Description : LDL receptor is specific for (A) Apo B-48 and Apo B 100 (B) Apo B-48 and Apo E (C) Apo B-100 and Apo D (D) Apo B-100 and apo D
Description : Receptors for chylomicron remnants are (A) Apo A specific (B) Apo B-48 specific (C) Apo C specific (D) Apo E specific
Description : The largest alpolipoprotein is (A) Apo E (B) Apo B-48 (C) Apo B-100 (D) Apo A-I
Description : If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity ... C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167
Description : A Holoenzyme is (A) Functional unit (B) Apo enzyme (C) Coenzyme (D) All of these
Description : The apolipoprotein which acts as actiator of extrahepatic lipoprotein is (A) Apo-A (B) Apo-B (C) Apo-C (D) Apo-D
Description : Which of the following statement(s) is/are true concerning the various types of shock? a. Traumatic shock is more commonly associated with subsequent organ injury and multiorgan failure ... responds quickly to resuscitation e. Neurogenic shock occurs with the absence of sympathetic activity
Last Answer : Answer: a, b, d, e Classification schemes of shock based on cause have been developed for the seemingly dissimilar processes leading to circulatory collapse and the shock state. ... and pressor agents. The response to exogenous corticosteroids is usually dramatic and potentially life-saving
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : Tyrosinosis is due to defect in the enzyme: (A) Fumarylacetoacetate hydrolase (B) p-Hydroxyphenylpyruvate hydroxylase (C) Tyrosine transaminase (D) Tyrosine hydroxylase
Description : Defect of lack of fusion is mainly due to? (i) Improper heating.* (ii) Improper Gap (iii) Improper grinding (iv) None of above
Last Answer : (i) Improper heating.*
Description : Defect of High joint is due to ? (i) Early trimming of weld (ii) Excess provision of height during alignment.* (iii) Early grinding of weld (iv) None of above
Last Answer : (ii) Excess provision of height during alignment.
Description : Defect of low joint is due to? (i) Excess height (ii) Early trimming of weld (iii) Early grinding of weld (iv) Nil/Less provision of height during alignment.
Last Answer : (iv) Nil/Less provision of height during alignment.
Description : Defect of short of metal is mainly due to? (i) Less gap (ii) Excessive gap* (iii) Less weight of position (iv) None of above
Last Answer : (ii) Excessive gap*
Description : Defect of cracks in weld is mainly due to? (i) Early opening of mould.* (ii) Early trimming of weld (iii) Early grinding of weld (iv) None of above
Last Answer : (i) Early opening of mould.*
Description : Defect of Blow holes is due to? (i) Slag (ii) Moisture* (iii) Lack of heating (iv) Extra heating
Last Answer : (ii) Moisture*
Description : When mailing personal correspondence First Class from an APO?
Last Answer : when mailing personal correspondence, First Class, from an APOto a stateside address, what can you use in place of postage
Description : What is a que 100 APO pill?
Last Answer : Need answer
Description : The main product of glycolysis under aerobic conditions is a. Pyruvate b. Lactate c. None of these d. Both a and b Ans: A 2. The protein moiety of an enzyme is known as a. Holo enzyme b. Apo enzyme c. Co enzyme d. Enzyme
Last Answer : Ans: B
Description : The APO shall renew its Certificate of Accreditation once every how many years after the date of the Resolution granting the petition for re-accreditation and the issuance of the said certificate upon submission of the requirements? a. 2 years b. 3 years c. 4 years d. 6 years
Last Answer : 3 years
Description : The APO shall submit its nominations with complete documentation to the Commission not later than ______ prior to the expiry of the term of an incumbent chairman or member. a. 30 days b. 60 days c. 90 days d. 120 days
Last Answer : 60 days
Description : Non protein part of enzyme is called (a) Iso-enzyme (b) Holo-enzyme (c) Apo-enzyme (d)Prosthatic group
Last Answer : (d)Prosthatic group
Description : Amylopectinosis is caused due to absence of (A) Debranching enzyme (B) Branching enzyme (C) Acid maltase (D) Glucose-6-phosphatase
Description : Cori disease (Limit dextrinosis) is caused due to absence of (A) Branching enzyme (B) Debranching enzyme (C) Glycogen synthase (D) Phosphorylase
Description : Galactosemia is due the absence of which enzyme?
Last Answer : Galactose-1-phosphate uridyl transferase.
Description : Which of the following helps in monitoring the Test Progress:- i. Percentage of Test Case Execution ii. Percentage of work done in test environment preparation. iii. Defect Information e.g. defect density, ... ii,iii are correct and iv is incorrect c) i,ii are correct and iii,iv are incorrect
Last Answer : b) i,ii,iii are correct and iv is incorrect
Description : Bilirubin UDP-glucuronyl transferase is absent from liver in (A) Crigler-Najjar syndrome, type I (B) Gilbert’s disease (C) Crigler-Najjar syndrome, type II (D) Rotor’s syndrome
Description : In Hurler’s syndrome, urine shows the presence of (A) Keratan sulphate I (B) Chondroitin sulphate (C) Dermatan sulphate and heparan sulphate (D) Keratan sulphate II
Description : Lesch-Nyhan syndrome, the sex linked recessive disorder is due to the lack of the enzyme: (A) Hypoxanthine-guanine phosphoribosyl transferse (B) Xanthine oxidase (C) Adenine phosphoribosyl transferase (D) Adenosine deaminase
Description : Stein-leventhal syndrome is due to overproduction of (A) Estrogens (B) Androgens (C) Gastogens (D) Ethinyl estradiol
Description : Ehlers-Danlos syndrome characterized by hypermobile joints and skin abnormalities is due to (A) Abnormality in gene for procollagen (B) Deficiency of lysyl oxidase (C) Deficiency of prolyl hydroxylase (D) Deficiency of lysyl hydroxylase
Description : Renal ricket is caused by renal tubular defect (usually inherited) which interferes with reabsorption of (A) Calcium (B) Phosphorous (C) Sodium (D) Chloride
Description : The probable metabolic defect in gents is (A) A defect in excretion of uric acid by kidney (B) An overproduction of pyrimidines (C) An overproduction of uric acid (D) Rise in calcium leading to deposition of calcium urate
Description : Xeroderma pigmentosum results from a defect in (A) uvr ABC excinuclease (B) DNA polymerase I (C) DNA ligase (D) All of these
Description : The defect in adrenal cortex responsible for lack of glucocorticoids and mineralcorticoids is (A) Androstenedione deficiency (B) 17 α -OH progesterone deficiency (C) C-21 hydroxylase deficiency (D) Testosterone deficiency HORMONE METABOLISM 209