A protein rich in hydroxyproline is (A) Prolamin (B) Procollagen (C) Collagen (D) Proinsulin

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Answer :

Answer : C

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Description : The vitamin required for the formation of hydroxyproline (in collagen) is (A) Vitamin C (B) Vitamin A (C) Vitamin D (D) Vitamin E

Last Answer : Answer : A

Description : Collagen and elastin have the following similarity: (A) Both are triple helices (B) Both have hydroxyproline residues (C) Both have hydrolysine residues (D) Both are glycoproteins

Last Answer : Answer : A

Description : All the following statement about hydroxyproline are true except (A) There is no codon for hydroxyproline (B) It is present in large amounts in collagen (C) Free proline cannot be hydroxylated to hydroxyproline (D) Hydroxylation of proline residues is catalysed by a dioxygenase

Last Answer : Answer : D

Description : Which of the following statement(s) is/are true concerning the proliferative phase of wound healing? a. The macrophage is the predominant cell type b. The pink or purple-red appearance of a wound ... amino acids, hydroxyproline and hydroxylysine d. The predominant collagen type in a scar is type 3

Last Answer : Answer: b, c The proliferative phase of wound healing begins with the formation of a provisional matrix of fibrin and fibronectin as part of the initial clot formation. Initially, the provisional ... The principal collagen type scar is type 1, with lesser amounts of type 3 collagen also present

Description : Which of the following interfere with normal collagen formation or cross-linking? A. Beta-aminopropionitrile. B. Iron chelators. C. Vitamin C depletion. D. Proline analogs (e.g., cis-hydroxyproline). E. D-Penicillamine.

Last Answer : Answer: ABCDE DISCUSSION: Intramolecular and intermolecular cross-links are crucial for collagen structural stability. Formation of cross-links can be inhibited by two ... concentration, proline analogs prevent collagen formation with minimal effects on noncollagenase protein synthesis

Description : Which of the following protein is rich in cysteine? (A) Elastine (B) Collagen (C) Fibrin (D) Keratin

Last Answer : Answer : D

Description : A protein rich in cysteine is (A) Collagen (B) Keratin (C) Haemoglobin (D) Gelatin

Last Answer : Answer : B

Description : The amino acid from which synthesis of the protein of hair keratin takes place is (A) Alanine (B) Methionine (C) Proline (D) Hydroxyproline

Last Answer : Answer : B

Description : Ehlers-Danlos syndrome characterized by hypermobile joints and skin abnormalities is due to (A) Abnormality in gene for procollagen (B) Deficiency of lysyl oxidase (C) Deficiency of prolyl hydroxylase (D) Deficiency of lysyl hydroxylase

Last Answer : Answer : A

Description : Collagen is very rich in (A) Glycine (B) Serine (C) Aspartic acid (D) Glutamic acid

Last Answer : Answer : A

Description : Proinsulin has (A) 74 amino acids (B) 86 amino acids (C) 105 amino acids (D) 109 amino acids

Last Answer : Answer : B

Description : Pre-proinsulin contains a signal sequence having (A) 9 amino acid residues (B) 19 amino acid residues (C) 27 amino acid residues (D) 33 amino acid residues

Last Answer : Answer : B

Description : What is proinsulin?

Last Answer : Insulin is synthesised as a large single polypeptide. Middle part of it is then removed, to form the A and B chains of insulin.

Description : Sulphur is made available to the body by the amino acids: (A) Cystine and methionine (B) Taurine and alanine (C) Proline and hydroxyproline (D) Arginine and lysine MINERAL METABOLISM 191

Last Answer : Answer : A

Description : Covalent modification of an enzyme usually involves phosphorylation / dephosphorylation of (A) Serine residue (B) Proline residue (C) Hydroxylysine residue (D) Hydroxyproline residue

Last Answer : Answer : A

Description : Carnitine is synthesized from (A) Lysine and methionine (B) Glycine and arginine (C) Aspartate and glutamate (D) Proline and hydroxyproline

Last Answer : Answer : A

Description : All of the following statements about proline are true except (A) It is an imino acid (B) It can be synthesized from glutamate (C) It can be catabolised to glutamate (D) Free proline can be hydroxylated to hydroxyproline

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Description : A protein having both structural and enzymatic traits is (A) Myosin (B) Collagen (C) Trypsin (D) Actin

Last Answer : Answer : A

Description : The most abundant protein in bones is (A) Collagen type I (B) Collagen type II (C) Collagen type III (D) Non-collagen proteins

Last Answer : Answer : A

Description : The most abundant protein in mammals is (A) Albumin (B) Haemoglobin (C) Collagen (D) Elastin

Last Answer : Answer : C

Description : In contrast to adult wound healing with scar formation, which of the following are characteristic of scarless fetal skin repair? A. Matrix rich in hyaluronic acid. B. Increased inflammatory response. C. Increased production of TGF-b. D. No collagen deposition. E. Minimal angiogenesis.

Last Answer : Answer: AE DISCUSSION: The ability of a fetus to heal without scar formation depends on its gestational age at the time of injury and the size of the wound defect. In ... repair has possible clinical applications in the modulation of adult fibrotic diseases and abnormal scar-forming conditions

Description : Which of the following statements is not correct? (a) In man insulin is synthesised as a proinsulin. (b) The proinsulin has an extra peptide called C-peptide. (c) The functional insulin has A and B chains linked together by hydrogen bonds. (d) Genetically engineered insulin is produced in E.Coli.

Last Answer : (c) The functional insulin has A and B chains linked together by hydrogen bonds.

Description : With regard to insulin: a. it is a 51 amino acid peptide b. it is formed by removal of C-chain from proinsulin c. it is produced by the alpha cells of the pancreas d. it alters the rate of enzyme synthesis

Last Answer : it alters the rate of enzyme synthesis

Description : Human insulins are obtained by the following sources/methods except: A. Cadaver pancreas B. Proinsulin recombinant bacterial C. Precursor yeast recombinant D. Enzyme modification of pork insulin

Last Answer : . Cadaver pancreas

Description : What protein forms a bridge between exposed vessel wall collagen and platelet surface receptors?

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Description : Factors that decrease collagen synthesis include all of the following except: A. Protein depletion. B. Infection. C. Anemia. D. Advanced age. E. Hypoxia.

Last Answer : Answer: C DISCUSSION: Collagen synthesis, an integral part of wound healing, is affected by many local and systemic factors. Protein depletion impairs fibroplasia. Hypoproteinemia leads to diminution of ... more than any other factor, wound infection is associated with the risk of wound failure

Description : Which one is the most abundant protein in the animal world? (a) Trypsin (b) Haemoglobin (c) Collagen (d) Insulin

Last Answer : (c) Collagen

Description : Which one of the following is the most abundant protein in the animals? (a) Haemoglobin (b) Collagen (c) Lectin (d) Insulin

Last Answer : (b) Collagen

Description : Collagen is (a) fibrous protein (b) globular protein (c) lipid (d) carbohydrate.

Last Answer : (a) fibrous protein

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Last Answer : Correct Answer: 3) Collagen

Description : This major protein component of connective tissue in mammals comprises most of the organic matter of skin, tendons, bones, and teeth, and occurs as fibrous inclusions in most other body structures. Is this material: a) elastin b) collagen c) fatty acids d) keratin

Last Answer : ANSWER: B -- collagen 

Description : The greatest buffering capacity at physiologic pH would be provided by a protein rich in which of the following amino acids ? (A) Lysine (B) Histidine (C) Aspartic acid (D) Valine

Last Answer : Answer : B

Description : The 2 energy rich compounds needed for protein biosynthesis are (A) ATP and GTP (B) ATP and UTP (C) ATP and CTP (D) ATP and TTP

Last Answer : Answer : A

Description : Give an example of a nutritionally rich protein (first class protein).

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Description : Fibronectin has binding sites for all of the following except (A) Glycophorin (B) Collagen (C) Heparin (D) Integrin receptor

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Description : Marfan’s syndrome results from a mutation in the gene coding: (A) Collagen (B) Elastin (C) Fibrillin (D) Keratin

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Description : A deficiency of copper effects the formation of normal collagen by reducing the activity of which of the following enzyme? (A) Prolyl hydroxylase (B) Lysyl oxidase (C) Lysyl hydroxylase (D) Glucosyl transferase

Last Answer : Answer : B

Description : Ascorbic acid is required to synthesise all of the following except (A) Collagen (B) Bile acids (C) Bile pigments (D) Epinephrine

Last Answer : Answer : C

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Description : Proteins that constitute keratin, collagen and elastin in body are (A) Protamines (B) Phosphol proteins (C) Scleroproteins (D) Metaproteins

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Description : Abnormal collagen structure is seen in all of the following except (A) I-cell disease (B) Osteogenesis imperfecta (C) Menke’s disease (D) Ehlers-Danlos sydrome

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Description : All of the following are glycoproteins except (A) Collagen (B) Albumin (C) Transferrin (D) IgM

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