Description : All the following statements about fibronectin are true except (A) It is glycoprotein (B) It is a triple helix (C) It is present in extra cellular matrix (D) It binds with integrin receptors of cell
Last Answer : Answer : A
Description : Which of the following is an adhesion glycoprotein? A. Fibronectin. B. Tenascin. C. Laminin. D. Hyaluronic acid. E. Collagen type IV.
Last Answer : Answer: ABC DISCUSSION: Cell adhesion glycoproteins such as fibronectin, vitronectin, laminin, and tenascin provide a railroad track to facilitate epithelial and mesenchymal cell migration over the wound ... , and collagen type IV is a protein that is a crucial component of basement membrane
Description : Insulin binding sites are present on the (A) α-subunits of insulin receptor (B) β-subunits of insulin receptor (C) γ-subunits of insulin receptor (D) α-and β−subunits of insulin receptor
Description : Tetracycline hydrochloride conditioning of root surfaces in periodontal surgery is to: A. Sterilise the root surface B. May enhance binding of fibronectin and fibroblast C. Aids in re-mineralising the root surface D. Assist the biding of lamina dura E. Prevents post operative infections
Last Answer : B. May enhance binding of fibronectin and fibroblast
Description : The function of a viral capsid is A.protection against the viral genome from physical and enzymatic destruction B.providing binding sites that enable the virus to attach to specific receptor sites on the host ... C.serving as a vehicle of transmission from one host to another D.all of the above
Last Answer : D.all of the above
Description : Glycophorin is present in cell membranes of (A) Erythrocytes (B) Platelets (C) Neutrophils (D) Liver
Description : Phosphorylated IRS-1 activates GRB-2 which is (A) G-protein receptor binding protein-2 (B) Growth factor receptor binding protein-2 (C) Growth hormone receptor binding protein-2 (D) Glucocorticoid receptor binding protein-2 226 MCQs IN BIOCHEMISTRY
Last Answer : Answer : B
Description : Binding of growth hormone to its receptor results in increased transcription of (A) c-fos gene (B) c-myc gene (C) p-53 gene (D) None of these
Description : Binding of growth hormone to its receptor results in phosphorylation of (A) JAK-2 (B) Growth hormone receptor (C) STATs (D) All of these
Last Answer : Answer : D
Description : Binding of insulin to its receptor activates (A) Adenylate cyclase (B) Guanylate cyclase (C) Phospholipase C (D) Tyrosine kinase
Description : The only correct statement about hormone receptors is (A) Receptors for protein hormones are present in cytosol (B) Receptors for steroid hormones are membrane bound (C) Hormone-receptor binding is irreversible (D) Receptors can undergo down regulation and up regulatoin
Description : Fibronectin is involved in (A) Cell adhension (B) Cell movement (C) Both (A) and (B) (D) None of these
Description : When compared to unfractionated heparin, low molecular weight heparins have (a) Preferential binding affinity to factor Xa relative to Iia (thrombin) (b) Shorter half-lives (c) Dose – dependent renal clearance
Last Answer : Ans: A
Description : The termination of heparin activity by protamine sulfate is due to (a) A chelating action (b) The inhibition of gastrointestinal absorption of heparin (c) The displacement of heparin-plasma protein binding (d) An acid-base interaction (e) The prothrombin-like activity of protamine
Last Answer : Ans: D
Description : The following examples are important heteropolysaccharides except (A) Amylopectin (B) Heparin (C) Peptidoglycan (D) Hyaluronic acid
Last Answer : A
Description : Ascorbic acid is required to synthesise all of the following except (A) Collagen (B) Bile acids (C) Bile pigments (D) Epinephrine
Last Answer : Answer : C
Description : Abnormal collagen structure is seen in all of the following except (A) I-cell disease (B) Osteogenesis imperfecta (C) Menke’s disease (D) Ehlers-Danlos sydrome
Description : All of the following are glycoproteins except (A) Collagen (B) Albumin (C) Transferrin (D) IgM
Description : All the following statement about hydroxyproline are true except (A) There is no codon for hydroxyproline (B) It is present in large amounts in collagen (C) Free proline cannot be hydroxylated to hydroxyproline (D) Hydroxylation of proline residues is catalysed by a dioxygenase
Description : If a coenzyme is required in an enzyme reaction, the former usually has the function of (A) Acting as an acceptor for one of the cleavage products of the substrate (B) Enhancing the specificity ... C) Increasing the number of receptor sites of the apo enzyme (D) Activating the substrate ENZYMES 167
Description : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as
Last Answer : `Ca^(+2),IP_(3),C-AMP` etc. Are generated after binding of hormone on receptor present on membrane thus these are termed as
Description : Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of ... protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor
Last Answer : Answer: a, d Although most hormone and other messenger receptors are extracellular, intracellular receptors have been identified. The hormone messengers involved for these receptors are primarily ... DNA-binding domain of the receptor. Activation involves the dissociation of the inhibitor protein
Description : Which of the following statement(s) is/are true concerning cell membrane receptors? a. The largest family of cell surface receptors are the G-protein-linked receptors b. Activities of the ... through the use adenylate cyclase d. Tyrosine kinase receptors are considered G-protein-linked receptors
Last Answer : Answer: a, c All water-soluble regulatory molecules bind to the cell surface receptor proteins. Binding of the appropriate ligand evokes an intracellular signal which usually regulates ... are adenylate cyclase, which converts ATP to cAMP, and the polyphosphoinositide-specific phospholipase C
Description : G-proteins: a. are activated by the binding of an extracellular ligand to a membrane receptor b. can be mutated in tumour cells c. mediate the action of glucocorticoid hormone d. they are inactivated by cholera toxins
Last Answer : are activated by the binding of an extracellular ligand to a membrane receptor
Description : _____ cells have antibodies on their surface that perform receptor functions by binding to antigen (epitope). a. T b. B c. NK d. A-C are correct
Last Answer : b. B
Description : The _____ cell contains on its surface a CD4 receptor site that enhances binding to the macrophage. a. Helper T b. molecular patterns (PAMPs) c. plasma d. B
Last Answer : a. IgG
Description : Clonal selection includes a. Antigen-receptor binding on B cells. b. Antibody secretion recognizing same epitope as on B cell receptors. c. Differentiation of B cells into plasma cells and memory cells. d. All the above (A—C) are correct.
Last Answer : d. All the above (A—C) are correct.
Description : Aliskiren acts by (A) inhibiting the conversion of Angiotensin I to II (B) inhibiting the release of rennin (C) inhibiting the binding of Angiotensin II to the receptor (D) inhibiting the action of aldosterone
Last Answer : (B) inhibiting the release of rennin
Description : Which is associated with a steroid hormone? A) cyclic AMP B) the second messenger system C) production of new proteins D) activation of proteins present in an inactive form E) binding of a protein to a surface receptor on the plasma membrane
Last Answer : C) production of new proteins
Description : The binding of prokaryotic DNA dependent RNA polymerase to promoter sites of genes is inhibited by the antibiotic: (A) Puromycin (B) Rifamycin (C) Terramycin (D) Streptomycin
Description : Tetracylin prevents synthesis of polypeptide by (A) Blocking mRNA formation from DNA (B) Releasing peptides from mRNA-tRNA complex (C) Competing with mRNA for ribosomal binding sites (D) Preventing binding of aminoacyl tRNA
Description : The following action(s) of heparin is/are essential for inhibition of factor Xa: A. Facilitation of antithrombin III mediated inhibition of factor XIIa B. Provision of scaffold for the clotting factor ... configurational change in antithrombin III to expose its interacting sites D. Both A' and B
Last Answer : C. Induction of a configurational change in antithrombin III to expose its interacting sites
Description : All the following statements about epidermal growth factor are true except (A) It is a protein (B) It possess quaternary structure (C) Its receptor is made up of a single polypeptide chain (D) Its receptor possesses tyrosine kinase domain
Description : All the following statements about TSH are true except (A) It is a glycoprotein (B) It is made up of α- and β-subunits (C) Receptor recognition involves both the subunits (D) Its subunit is identical with those of FSH and LH
Description : Heparin is contraindicated in patients suffering from the following diseases except: A. Pulmonary tuberculosis B. Bleeding due to defibrination syndrome C. Subacute bacterial endoc
Last Answer : B. Bleeding due to defibrination syndrome
Description : Low molecular weight heparins have the following advantages over unfractionated heparin except: A. Higher efficacy in arterial thrombosis B. Less frequent dosing C. Higher and more consistent subcutaneous bioavailability D. Laboratory monitoring of response not required
Last Answer : A. Higher efficacy in arterial thrombosis
Description : The following is true of heparin except: A. Sudden stoppage of continuous heparin therapy causes rebound increase in blood coagulability B. High doses of heparin inhibit platelet aggregation ... active circulating anticoagulant D. Heparin clears lipemic plasma in vivo but not in vitro
Last Answer : C. Heparin is the physiologically active circulating anticoagulant
Description : All the following cells produces collagen except :-
Last Answer : All the following cells produces collagen except :- A. Osteoblast B. Chondroblast C. Fibro blast D. Mast cells
Description : Factors that decrease collagen synthesis include all of the following except: A. Protein depletion. B. Infection. C. Anemia. D. Advanced age. E. Hypoxia.
Last Answer : Answer: C DISCUSSION: Collagen synthesis, an integral part of wound healing, is affected by many local and systemic factors. Protein depletion impairs fibroplasia. Hypoproteinemia leads to diminution of ... more than any other factor, wound infection is associated with the risk of wound failure
Description : Chemotactic factors are produced by EXCEPT: D A. Lymphocytes B. Monocytes C. Endothelial cells D. Collagen
Last Answer : Collagen
Description : Receptor sites for neurotransmitters are present on (a) pre-synaptic membrane (b) tips of axons (c) post-synaptic membrane (d) membranes of synaptic vesicles.
Last Answer : (c) post-synaptic membrane
Description : Which of the following is NOT correct about hormones? A) Hormones are generally found across the animal kingdom. B) Hormones may be used at a distance from where the hormone is made. C) ... target cell. E) Hormones are directed to the target organ and avoid contact with non-target cells.
Last Answer : E) Hormones are directed to the target organ and avoid contact with non-target cells.
Description : Select the correct statement about benzodiazepines (BZDs): A. All BZDs facilitate GABA mediated Cl¯ influx into neurones B. Different BZDs exert the same degrees of hypnotic, anxiolytic and anticonvulsant ... at all neuronal sites D. The muscle relaxant action of BZDs is not blocked by flumazenil
Last Answer : A. All BZDs facilitate GABA mediated Cl¯ influx into neurones
Description : Receptor sites for neurotransmitters are present on : (1) Pre-synaptic membrane (2) Tips of axons (3) Post-synaptic membrane (4) Membrane of synaptic vesicles
Last Answer : (3) Post-synaptic membrane
Description : Heparin releasable hepatic lipase converts (A) VLDL remnants into LDL (B) Nascent HDL into HDL (C) HDL2 into HDL3 (D) HDL3 into HDL2
Description : Hyaluronidase hydrolyses (A) Hyaluronic acid (B) Chondroitin sulphate (C) Heparin (D) Hyaluronic acid and chondroitin sulphate
Description : Synovial fluid contains (A) Heparin (B) Hyaluronic acid (C) Chondroitin sulphate (D) Keratin sulphate
Last Answer : B
Description : N–Acetylglucosamnine is present in (A) Hyaluronic acid (B) Chondroitin sulphate (C) Heparin (D) All of these
Description : A heteropolysacchraide among the following is (A) Inulin (B) Cellulose (C) Heparin (D) Dextrin
Last Answer : C
Description : α–D–Glucuronic acid is present in (A) Hyaluronic acid (B) Chondroitin sulphate (C) Heparin (D) All of these