Liposomes are (A) Lipid bilayered (B) Water in the middle (C) Carriers of drugs (D) All of these

Liposomes are (A) Lipid bilayered (B) Water in the middle (C) Carriers of drugs (D) All of these
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Mention the application of liposomes in pharmacy.

Description : Mention the application of liposomes in pharmacy.

Last Answer : i)Used in disease caused by intracellular parasites e.g. malaria, tuberculosis and amoebiasis. ii)Liposomes entrapped insulin active orally and can be replaced by intramuscular administration if ... vi)Liposome entrapped actinomycin-D and nitrogen mustard are more effective than parent drug.

6 The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : 6 The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Description : The blood-brain barrier, which restricts entry of many drugs into brain, is constituted by: A. P-glycoprotein efflux carriers in brain capillary cells B. Tight junctions between endothelial cells of brain capillaries C. Enzymes present in brain capillary walls D. All of the above

Last Answer : D. All of the above

Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs C. They do not worsen blood lipid profile D. They do not impair work performance

Description : Advantages of angiotensin converting enzyme inhibitors as antihypertensive include the following except: A. They tend to reverse left ventricular hypertrophy B. Their efficacy is not reduced by nonsteroidal ... . They do not worsen blood lipid profile D. They do not impair work performance

Last Answer : B. Their efficacy is not reduced by nonsteroidal antiinflammatory drugs

Biotransformation of drugs is primarily directed to: A. Activate the drug B. Inactivate the drug C. Convert lipid soluble drugs into nonlipid soluble metabolites D. Convert nonlipid soluble drugs into lipid soluble metabolites

Description : Biotransformation of drugs is primarily directed to: A. Activate the drug B. Inactivate the drug C. Convert lipid soluble drugs into nonlipid soluble metabolites D. Convert nonlipid soluble drugs into lipid soluble metabolites

Last Answer : C. Convert lipid soluble drugs into nonlipid soluble metabolites

Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage of lipid soluble drugs into the brain C. It limits entry of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Description : Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage ... of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Last Answer : D. It regulates passage of substances from brain into blood

Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Description : Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Last Answer : A. Highly lipid soluble drugs

04. The main mechanism of most drugs absorption in GI tract is: a) Active transport (carrier-mediated diffusion) b) Filtration (aqueous diffusion) c) Endocytosis and exocytosis d) Passive diffusion (lipid diffusion)

Description : 04. The main mechanism of most drugs absorption in GI tract is: a) Active transport (carrier-mediated diffusion) b) Filtration (aqueous diffusion) c) Endocytosis and exocytosis d) Passive diffusion (lipid diffusion)

Last Answer : PHARMACOKINETICS

Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage of lipid soluble drugs into the brain C. It limits entry of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Description : Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage ... of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Last Answer : D. It regulates passage of substances from brain into blood

Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Description : Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Last Answer : A. Highly lipid soluble drugs

The most important factor which governs diffusion of drugs across capillaries other than those in the brain is: A. Blood flow through the capillary B. Lipid solubility of the drug C. pKa value of the drug D. pH of the medium

Description : The most important factor which governs diffusion of drugs across capillaries other than those in the brain is: A. Blood flow through the capillary B. Lipid solubility of the drug C. pKa value of the drug D. pH of the medium

Last Answer : A. Blood flow through the capillary

Biotransformation of drugs is primarily directed to: A. Activate the drug B. Inactivate the drug C. Convert lipid soluble drugs into nonlipid soluble metabolites D. Convert nonlipid soluble drugs into lipid soluble metabolites

Description : Biotransformation of drugs is primarily directed to: A. Activate the drug B. Inactivate the drug C. Convert lipid soluble drugs into nonlipid soluble metabolites D. Convert nonlipid soluble drugs into lipid soluble metabolites

Last Answer : C. Convert lipid soluble drugs into nonlipid soluble metabolites

Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage of lipid soluble drugs into the brain C. It limits entry of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Description : Which of the following is not true of the blood-brain barrier: A. It is constituted by tight junctions between the endothelial cells of brain capillaries and the glial tissue B. It allows passage ... of highly ionized drugs into the brain D. It regulates passage of substances from brain into blood

Last Answer : D. It regulates passage of substances from brain into blood

Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Description : Marked redistribution is a feature of: A. Highly lipid soluble drugs B. Poorly lipid soluble drugs C. Depot preparations D. Highly plasma protein bound drugs

Last Answer : A. Highly lipid soluble drugs

The most important factor which governs diffusion of drugs across capillaries other than those in the brain is: A. Blood flow through the capillary B. Lipid solubility of the drug C. pKa value of the drug D. pH of the medium

Description : The most important factor which governs diffusion of drugs across capillaries other than those in the brain is: A. Blood flow through the capillary B. Lipid solubility of the drug C. pKa value of the drug D. pH of the medium

Last Answer : A. Blood flow through the capillary

G-proteins act as (A) Hormone carriers (B) Hormone receptors (C) Second messengers (D) Signal transducers

Description : G-proteins act as (A) Hormone carriers (B) Hormone receptors (C) Second messengers (D) Signal transducers

Last Answer : Answer : D

All the following statements about steroid hormones are true except (A) They are hydrophobic (B) They require carriers to transport them in circulation (C) Their receptors are intracellular (D) They require cyclic AMP as second messenger

Description : All the following statements about steroid hormones are true except (A) They are hydrophobic (B) They require carriers to transport them in circulation (C) Their receptors are intracellular (D) They require cyclic AMP as second messenger

Last Answer : Answer : D

All the following statements about hormones are true except (A) All of them require specific carriers in plasma (B) All of them require specific receptors in target cells (C) Some of them are subject to feedback regulation (D) Some of them increase the transcription of certain genes

Description : All the following statements about hormones are true except (A) All of them require specific carriers in plasma (B) All of them require specific receptors in target cells (C) Some of them are subject to feedback regulation (D) Some of them increase the transcription of certain genes

Last Answer : Answer : A

The correct sequence of cytochrome carriers in respiratory chain is (A) Cyt b—cyt c—cyt c1—cyt aa3 (B) Cyt aa3— cyt b—cyt c—cyt c1 (C) Cyt b—cyt c1—cyt c—cyt aa3 (D) Cyt b—cyt aa3—cyt c1— cyt c

Description : The correct sequence of cytochrome carriers in respiratory chain is (A) Cyt b—cyt c—cyt c1—cyt aa3 (B) Cyt aa3— cyt b—cyt c—cyt c1 (C) Cyt b—cyt c1—cyt c—cyt aa3 (D) Cyt b—cyt aa3—cyt c1— cyt c

Last Answer : Answer : C

The redox carriers are grouped into respiratory chain complex (A) In the inner mitochondrial membrane (B) In mitochondiral matrix (C) On the outer mitochondrial membrane (D) On the inner surface of outer mitochondrial membrane

Description : The redox carriers are grouped into respiratory chain complex (A) In the inner mitochondrial membrane (B) In mitochondiral matrix (C) On the outer mitochondrial membrane (D) On the inner surface of outer mitochondrial membrane

Last Answer : Answer : A

Biological activity of tocopherols has been attributed in part to their action as (A) Antioxidant (B) Anticoagulents (C) Provitamin (D) Carriers in electron transport system

Description : Biological activity of tocopherols has been attributed in part to their action as (A) Antioxidant (B) Anticoagulents (C) Provitamin (D) Carriers in electron transport system

Last Answer : Answer : B

Action of insulin on lipid metabolism is (A) It increases lipolysis and increases triglyceride synthesis (B) It decreases lipolysis and increases triglyceride synthesis (C) It decreases lipolysis and decreases triglyceride synthesis (D) It increases synthesis of triglyceride and increased ketogenesis

Description : Action of insulin on lipid metabolism is (A) It increases lipolysis and increases triglyceride synthesis (B) It decreases lipolysis and increases triglyceride synthesis (C) It decreases ... and decreases triglyceride synthesis (D) It increases synthesis of triglyceride and increased ketogenesis

Last Answer : Answer : B

B.M.R. is raised in (A) Polycythemia (B) Starvation (C) Lipid nephrosis (D) Hypothyroidism

Description : B.M.R. is raised in (A) Polycythemia (B) Starvation (C) Lipid nephrosis (D) Hypothyroidism

Last Answer : Answer : A

Humans most easily tolerate a lack of the nutrient: (A) Protein (B) Lipid (C) Iodine (D) Carbohydrate

Description : Humans most easily tolerate a lack of the nutrient: (A) Protein (B) Lipid (C) Iodine (D) Carbohydrate

Last Answer : Answer : D

An enzyme is a (A) Carbohydrate (B) Lipid (C) Protein (D) Nucleic acid ENZYMES 171

Description : An enzyme is a (A) Carbohydrate (B) Lipid (C) Protein (D) Nucleic acid ENZYMES 171

Last Answer : Answer : C

Humans most easily tolerate a lack of which of the following nutrients? (A) Protein (B) Iodine (C) Carbohydrate (D) Lipid

Description : Humans most easily tolerate a lack of which of the following nutrients? (A) Protein (B) Iodine (C) Carbohydrate (D) Lipid

Last Answer : Answer : C

High iodine value of a lipid indicates (A) Polymerization (B) Carboxyl groups (C) Hydroxyl groups (D) Unsaturation

Description : High iodine value of a lipid indicates (A) Polymerization (B) Carboxyl groups (C) Hydroxyl groups (D) Unsaturation

Last Answer : Answer : D

Which of the following features is predicted by the Nicolson–Singer fluid mosaic model of biological membranes? (A) Membrane lipids do not diffuse laterally (B) Membrane lipid is primarily in a monolayer form (C) Membrane lipids freely flip-flop (D) Membrane proteins may diffuse laterally

Description : Which of the following features is predicted by the Nicolson–Singer fluid mosaic model of biological membranes? (A) Membrane lipids do not diffuse laterally (B) Membrane lipid is primarily in a monolayer form (C) Membrane lipids freely flip-flop (D) Membrane proteins may diffuse laterally

Last Answer : Answer : D

Most animal tissues contain appreciable amounts of lipid, when in the form of depot fat it consists largely of (A) Cholesterol ester (B) Phosphatides (C) Chylomicrons (D) Triacylglycerol

Description : Most animal tissues contain appreciable amounts of lipid, when in the form of depot fat it consists largely of (A) Cholesterol ester (B) Phosphatides (C) Chylomicrons (D) Triacylglycerol

Last Answer : Answer : D

The calorific value of lipid is (A) 4.0 Kcal/gm (B) 6.0 Kcal/gm (C) 9.0 Kcal/gm (D) 15 Kcal/gm

Description : The calorific value of lipid is (A) 4.0 Kcal/gm (B) 6.0 Kcal/gm (C) 9.0 Kcal/gm (D) 15 Kcal/gm

Last Answer : Answer : C

Which of the following lipid is absorbed actively from intestines? (A) Glycerol (B) Cholesterol (C) Monoacylglycerol (D) None of these

Description : Which of the following lipid is absorbed actively from intestines? (A) Glycerol (B) Cholesterol (C) Monoacylglycerol (D) None of these

Last Answer : Answer : D

Lipid stores are mainly present in (A) Liver (B) Brain (C) Muscles (D) Adipose tissue

Description : Lipid stores are mainly present in (A) Liver (B) Brain (C) Muscles (D) Adipose tissue

Last Answer : Answer : D

The major lipid in chylomicrons is (A) Triglycerides (B) Phospholipids (C) Cholesterol (D) Free fatty acids

Description : The major lipid in chylomicrons is (A) Triglycerides (B) Phospholipids (C) Cholesterol (D) Free fatty acids

Last Answer : Answer : A

A lipid containing alcoholic amine residue is (A) Phosphatidic acid (B) Ganglioside (C) Glucocerebroside (D) Sphingomyelin

Description : A lipid containing alcoholic amine residue is (A) Phosphatidic acid (B) Ganglioside (C) Glucocerebroside (D) Sphingomyelin

Last Answer : Answer : D

Deficiency of urea cycle enzymes results into accumulation of citrulline argininosuccinate arginine in the liver resulting in increasing concentration of …….. in the blood. (A) Calcium (B) Sodium (C) Ammonia (D) Lipid

Description : Deficiency of urea cycle enzymes results into accumulation of citrulline argininosuccinate arginine in the liver resulting in increasing concentration of …….. in the blood. (A) Calcium (B) Sodium (C) Ammonia (D) Lipid

Last Answer : Answer : C

Michaelis – Menten equation is used to explain the effect of substrate concentration on (A) Carbohydrate (B) Enzyme (C) Lipid (D) Protein

Description : Michaelis – Menten equation is used to explain the effect of substrate concentration on (A) Carbohydrate (B) Enzyme (C) Lipid (D) Protein

Last Answer : Answer : B

Deficiency of biotin results in decrease in (A) Amino acid synthesis (B) Lipid synthesis (C) Kidney (D) Fatty acid synthesis

Description : Deficiency of biotin results in decrease in (A) Amino acid synthesis (B) Lipid synthesis (C) Kidney (D) Fatty acid synthesis

Last Answer : Answer : D

The building up and breaking down of protoplasm are concerned with the metabolism of (A) Carbohydrate (B) Lipid (C) Protein (D) Minerals

Description : The building up and breaking down of protoplasm are concerned with the metabolism of (A) Carbohydrate (B) Lipid (C) Protein (D) Minerals

Last Answer : Answer : C

Lipid content of egg white is (A) 12% (B) 33% (C) 10–11% (D) Traces

Description : Lipid content of egg white is (A) 12% (B) 33% (C) 10–11% (D) Traces

Last Answer : Answer : D

A lipid bilayer is permeable to (A) Urea (B) Fructose (C) Glucose (D) Potassium

Description : A lipid bilayer is permeable to (A) Urea (B) Fructose (C) Glucose (D) Potassium

Last Answer : A

The ability of the cell membrane to act as a selective barrier depends upon (A) The lipid composition of the membrane (B) The pores which allows small molecules (C) The special mediated transport systems (D) All of these

Description : The ability of the cell membrane to act as a selective barrier depends upon (A) The lipid composition of the membrane (B) The pores which allows small molecules (C) The special mediated transport systems (D) All of these

Last Answer : D

Which of the following statement is correct about membrane cholesterol? (A) The hydroxyl group is located near the centre of the lipid layer (B) Most of the cholesterol is in the form of a cholesterol ester (C) The steroid nucleus form forms a rigid, planar structure (D) The hydrocarbon chain of cholesterol projects into the extracellular fluid

Description : Which of the following statement is correct about membrane cholesterol? (A) The hydroxyl group is located near the centre of the lipid layer (B) Most of the cholesterol is in the form ... forms a rigid, planar structure (D) The hydrocarbon chain of cholesterol projects into the extracellular fluid

Last Answer : C

All the following processes occur rapidly in the membrane lipid bilayer except (A) Flexing of fatty acyl chains (B) Lateral diffusion of phospholipids (C) Transbilayer diffusion of phopholipids (D) Rotation of phospholipids around their long axes

Description : All the following processes occur rapidly in the membrane lipid bilayer except (A) Flexing of fatty acyl chains (B) Lateral diffusion of phospholipids (C) Transbilayer diffusion of phopholipids (D) Rotation of phospholipids around their long axes

Last Answer : C

Which of the following phospholipids is localized to a greater extent in the outer leaflet of the membrane lipid bilayer? (A) Choline phosphoglycerides (B) Ethanolamine phosphoglycerides (C) Inositol phosphoglycerides (D) Serine phosphoglycerides

Description : Which of the following phospholipids is localized to a greater extent in the outer leaflet of the membrane lipid bilayer? (A) Choline phosphoglycerides (B) Ethanolamine phosphoglycerides (C) Inositol phosphoglycerides (D) Serine phosphoglycerides

Last Answer : A

Which of the following features would be expected on lipid analysis in a 57 year old female with two year history of primary biliary cirrhosis? 1) A lipaemic appearance of the serum would be expected. 2) is treated with clofibrate therapy 3) is characteristically associated with tendon xanthomas 4) is characteristically associated with palmar xanthomas 5) No evidence of a dyslipidaemia would be expected with this short a duration of disease

Description : Which of the following features would be expected on lipid analysis in a 57 year old female with two year history of primary biliary cirrhosis? 1) A lipaemic appearance of the serum would be ... xanthomas 5) No evidence of a dyslipidaemia would be expected with this short a duration of disease

Last Answer : Answers-4 In prolonged cholestasis features include: increased serum cholesterol, a moderate increase in triglyceride, the serum is not lipaemic, and reduced HDL levels. Clinical features include: ... persisted for more than 3 months sometimes fat deposits may involve bone and peripheral nerves.

Why do cell phone carriers push you to always upgrade your phone?

Description : Why do cell phone carriers push you to always upgrade your phone?

Last Answer : This last guy couldn't understand why I didn't have a smartphone, I told him very abruptly my dislike for smartphones, and he told me , well they still make the flip at least up grade to a new flip ... with my phone and if it dies I will upgrade then and not before, he just couldn't understand that.

What do you think of the US Navy's new carrier's price tag?(Details)

Description : What do you think of the US Navy's new carrier's price tag?(Details)

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Do you know the steps to switching cellular carriers?

Description : Do you know the steps to switching cellular carriers?

Last Answer : What is Project Fi?

Are US air carriers looking to purchase Tupelov TU-214s?

Description : Are US air carriers looking to purchase Tupelov TU-214s?

Last Answer : I don’t know, but the main problems of Russian aircraft was maintenance. That said most US carriers buy equipment that is similar and has the common parts, i.e. engines, aeronautics, computers.. The Russian planes would be different.