Description : All the following statements about ceruloplasmin are correct except (A) It is a copper-containing protein (B) It possesses oxidase activity (C) It is synthesised in intestinal mucosa (D) Its plasma level is decreased inWilson’s disease
Last Answer : Answer : C
Description : Ceruloplasmin is absent in (A) Cirrhosis of liver (B) Wilson’s disease (C) Menke’s disease (D) Copper deficiency
Last Answer : Answer : B
Description : All the following statements about Wilson’s disease are correct except (A) It is a genetic disease (B) The defect involves copper-dependent P-type ATPase (C) Copper is deposited in liver, basal ganglia and around cornea (D) Plasma copper level is increased in it
Last Answer : Answer : D
Description : Menke’s disease (Kinky or steel hair disease) is a X-linked disease characterized by (A) High levels of plasma copper (B) High levels of ceruloplasmin (C) Low levels of plasma copper and of ceuloplasmin (D) High level of hepatic copper
Description : All of the following are true of Wilson’s disease except (A) Low total plasma Cu (B) Elevated urinary copper (C) Arthritis (D) Aminoaciduria
Description : Iron absorption is hampered by (A) In achlorhydria (B) When ferritin content of intestinal mucosa is low (C) When saturation of plasma transferring is low (D) When erythropoietic activity is increased
Last Answer : Answer : A
Description : What is ceruloplasmin? (A) Plasma protein (B) Stored form of copper (C) Both A and B (D) None of these
Description : The surface tension in intestinal lumen between fat droplets and aqueous medium is decreased by (A) Bile Salts (B) Bile acids (C) Conc. H2SO4 (D) Acetic acid
Last Answer : A
Description : Which of the following medications used for the treatment of obesity prevents the absorption of triglycerides? a) Orlistat (Xenical) Orlistat (Xenical) prevents the absorption of triglycerides. Side effects of ... (Prozac) has not been approved by the FDA for use in the treatment of obesity.
Last Answer : a) Orlistat (Xenical) Orlistat (Xenical) prevents the absorption of triglycerides. Side effects of Xenical may include increased bowel movements, gas with oily discharge, decreased food absorption, decreased bile flow, and decreased absorption of some vitamins.
Description : A high plasma calcium level decreases intestinal absorption of calcium by (A) Stimulating the secretion of parathormone (B) Inhibiting the secretion of parathormone (C) Decreasing the synthesis of cholecalciferol (D) Inhibiting the secretion of thyrocalcitonin
Description : Current concepts concerning the intestinal absorption of triacylglycerols are that (A) They must be completely hydrolysed before the constituent fatty acids can be absorbed (B) They are hydrolysed partially ... portal blood (D) In the absence of bile the hydrolysis of triacyl glycerols is absorbed
Description : In case of wilson’s disease, the features include all of the following except (A) Progressive hepatic cirrhosis (B) Keyser Fleisher ring (C) Aminoaciduria (D) Urinary excretion of Cu is decreased
Description : Hypolipidemic drugs reduce serum cholesterol and triacylglycerol. The effect of clofibrate is attributed to (A) Block in absorption from G.I.T. (B) Decrease in secretion of triacylglycerol and cholesterol ... by liver (C) Block in the reabsorption of bile acids (D) Decreased synthesis of cholesterol
Last Answer : (A) Bile Salts
Description : Select the hypocholesterolemic drug which interferes with intestinal absorption of bile salts and cholesterol, and secondarily increases cholesterol turnover in the liver: A. Gemfibrozil B. Cholestyramine C. Lovastatin D. Bezafibrate
Last Answer : B. Cholestyramine
Description : Wilson’s disease is a condition of toxicosis of (A) Iron (B) Copper (C) Chromium (D) Molybdenum
Description : Drugs which undergo high degree of first-pass metabolism in liver: A. Have low oral bioavailability B. Are excreted primarily in bile C. Are contraindicated in liver disease D. Exhibit zero order kinetics of elimination
Last Answer : A. Have low oral bioavailability
Description : All the following statements about obstructive jaundice are true except (A) Prothrombin time may be prolonged due to impaired absorption of vitamin K (B) Serum alkaline phosphatase may be raised ... systemic circulation due to biliary obstruction (D) There is no defect in conjugation of bilirubin
Description : Intestinal absorption of magnesium is increased in (A) Calcium deficient diet (B) High calcium diet (C) High oxalate diet (D) High phytate diet
Description : PTH causes all of the following except (A) Increased intestinal absorption of calcium (B) Increased intestinal absorption of phosphate (C) Increased tubular reabsorption of calcium (D) Increased tubular reabsorption of phosphate
Description : Cholesterol is excreted as such into ________. (A) Urine (B) Faeces (C) Bile (D) Tears FATS AND FATTY ACID METABOLISM 99
Description : Which of the following statements about Menke’s disease are true. (A) It is an inherited disorder of copper metabolism (B) It occurs only in males (C) Plasma copper is increased in it (D) Hair becomes steely and kinky in it
Description : Serum ferroxidase level decreases in (A) Gaucher’s disease (B) Cirrhosis of liver (C) Acute pancreatitis (D) Wilson’s disease ENZYMES 143
Description : Serum acid phosphatase level increases in (A) Metastatic carcinoma of prostate (B) Myocardial infarction (C) Wilson’s disease (D) Liver diseases
Description : Ceruloplasmin oxidizes (A) Copper (B) Iron (C) Both (A) and (B) (D) None of these
Description : Oedema can occur when (A) Plasma Na and Cl are decreased (B) Plasma Na and Cl are increased (C) Plasma proteins are decreased (D) Plasma proteins are increased
Description : Increased serum alanine during fasting is due to (A) Breakdown of muscle proteins (B) Decreased utilization of non essential amino acids (C) Leakage of aminoacids to plasma (D) Impaired renal function
Description : The following metabolic abnormalities occur in Diabetes mellitus except (A) Increased plasma FFA (B) Increased pyruvate carboxylase activate (C) Decreased lipogenesis (D) Decreased gluconeogenesis
Last Answer : B
Description : Under certain circumstances, the gut may become a source of sepsis and serve as the motor of systemic inflammatory response syndrome. Microbial translocation is the process by which microorganisms ... intestinal mucosal permeability c. Decreased host defense mechanisms d. Lack of enteral feeding
Last Answer : Answer: a, b, c, d 99 Translocation is promoted in three general ways: 1) altered permeability of the intestinal mucosa as caused by shock, sepsis, distant injury, or cell toxins; 2) ... trauma patient d. Fifty percent of non-nitrogen caloric requirements should be provided in the form of fat
Description : Secretin causes all of the following except (A) Secretion of pancreatic juice (B) Secretion of bile (C) Inhibition of gastric secretion (D) Stimulation of intestinal motility
Description : On average red blood cells live around 120 days. The spleen is the main organ where old red blood cells are destroyed. During the red blood cell destruction the heme groups turn into bilirubin and this substance is then captured by the liver and later excreted in the bowels as part of the bile.
Last Answer : What are the functions of the spleen?
Description : Zinc deficiency occurs commonly in (A) Acrodermatitis enteropathica (B) Wilson’s disease (C) Xeroderma pigmentosum (D) Menke’s disease
Description : Accumulation of trytophan in blood is known as (A) Pompe’s disease (B) Wilson’s disease (C) Wolman’s disease (D) Hartnup’s disease
Description : Deficiency of vitamin B12 can occur because of (A) Decreased intake of vitamin B12 (B) Atrophy of gastric mucosa (C) Intestinal malabsorption (D) All of these
Description : Characteristics of Vitamin D and its metabolites include which one of the following? (a) Act to decrease serum levels of calcium (b) Activation of their Vitamin D receptors increases cellular CAMP ... Vitamin D increase renal excretion of calcium (e) Vitamin D deficiency results in Pager's disease
Last Answer : Ans: C
Description : How bile salts help in the absorption of dietary lipids?
Last Answer : By emulsifying the lipids and producing micelles of lipids.
Description : Answer: a, b, c, d Free oxygen radicals are chemical species that are intermediates in the normal process of cellular respiration. Oxidants that are free radicals have been implicated as initiators of ... a. C-reactive protein b. Serum amyloid c. a -Proteinase inhibitor d. Fibrinogen e. Albumin
Last Answer : Answer: a, b, c, d The acute-phase response is a series of homeostatic responses of the organism to tissue injury in infection and inflammation. After an inflammatory stimulus occurs, a number ... 30% to 50% of the level before injury. The reason for the decrease in production is poorly understood
Description : Each of the following may contribute to formation of oedema EXCEPT C A. decreased plasma oncotic pressure increased intravascular hydrostatic pressure C. increased serum albumin D. decreased serum proteins
Last Answer : increased serum albumi
Description : Each of the following produce edema EXCEPT: C A. Decreased plasma protein B. Depletion of sodium C. Increased capillary hydrostatic pressure D. None of these
Last Answer : Increased capillary hydrostatic pressure
Description : The following occur in untreated insulin dependent diabetes mellitus: a. diuresis b. decreased plasma amino acid c. increased plasma fatty acid d. ketonuria
Last Answer : ketonuria
Description : Calcium absorption is interfered by (A) Protein in diet (B) Phytic acid in cereals (C) Alkaline intestinal pH (D) Vitamin D
Description : Intestinal absorption of zinc is retarded by (A) Calcium (B) Cadmium (C) Phytate (D) All of these
Description : Calcitriol facilitates calcium absorption by increasing the synthesis of the following in intestinal mucosa: (A) Calcium Binding Protein (B) Alkaline Phosphatase (C) Calcium-dependent ATPase (D) All of these
Description : Intestinal absorption of calcium occurs by (A) Active takeup (B) Simple diffusion (C) Facilitated diffusion (D) Endocytosis
Description : Intestinal absorption of chromium is shared with (A) Mn (B) Mg (C) Ca (D) Zn
Description : The harmone acting directly on intestinal mucosa and stimulating glucose absorption is (A) Insulin (B) Glucagon (C) Thyroxine (D) Vasopressin
Description : Vitamin C enhances the intestinal absorption of (A) Potassium (B) Iodine (C) Iron (D) None of these
Description : Bile, an emulsifier liquid, is made by the liver and later stored within the gallbladder and released in the duodenum. Bile is composed of bile salts, cholesterol and bile pigments. ... enzymes that break fats into simpler fatty acids and glycerol. Digestion System - Image Diversity: gallbladder
Last Answer : What is the adnexal organ of the digestive system in which bile is stored?
Description : A young infant may be feeding entirely on mother's milk which is white in colour but the stools which the infant passes out is quite yellowish. What is this yellow colour due to? (a) ... bile juice (b) Undigested milk protein casein (c) Pancreatic juice poured into duodenum (d) Intestinal juice
Last Answer : (a) Bile pigments passed through bile juice